Hspa12b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hspa12b
Entrez Gene ID	311427
Full Name	heat shock protein family A (Hsp70) member 12B
General protein information	Preferred Names heat shock protein family A (Hsp70) member 12B Names heat shock 70 kDa protein 12B heat shock protein 12B heat shock protein 70kDa 12B
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q36

mRNA and Protein(s)

mRNA	Protein	Name
XM_006235028.3	XP_006235090.1	heat shock 70 kDa protein 12B isoform X1
NM_001107778.1	NP_001101248.1	heat shock 70 kDa protein 12B
XM_006235027.3	XP_006235089.1	heat shock 70 kDa protein 12B isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Regulation of A-Kinase-Anchoring Protein 12 by Heat Shock Protein A12B to Prevent Ventricular Dysfunction Following Acute Myocardial Infarction in Diabetic Rats.
Selvaraju V, Suresh SC, Thirunavukkarasu M, Mannu J, Foye JLC, Mathur PP, Palesty JA, Sanchez JA, McFadden DW, Maulik N
Journal of cardiovascular translational research10(2)209-220(2017 Apr)

Expression of HSPA12B in acute cardiac allograft rejection in rats.
Shi J, Yang D, Cong X, Li Y, Yang X, Liu Y
Pathology, research and practice211(1)20-6(2015 Jan)

The role of HSPA12B in regulating neuronal apoptosis.
Kang L, Zhang G, Yan Y, Ke K, Wu X, Gao Y, Li J, Zhu L, Wu Q, Zhou Z
Neurochemical research38(2)311-20(2013 Feb)

Lipopolysaccharide-evoked HSPA12B expression by activation of MAPK cascade in microglial cells of the spinal cord.
Cui Z, Wang P, Sun L, Liu H, Yang J, Li X, Kang L, Huang Y, Shen A, Cheng C
Journal of the neurological sciences294(1-2)29-37(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

HSPA12B overexpression interacts with AKAP12 and downregulate TXNIP in diabetic rats following acute myocardial infarction.
Title: Regulation of A-Kinase-Anchoring Protein 12 by Heat Shock Protein A12B to Prevent Ventricular Dysfunction Following Acute Myocardial Infarction in Diabetic Rats.

HSPA12B might play crucial roles in heart pathophysiology after transplantation
Title: Expression of HSPA12B in acute cardiac allograft rejection in rats.

The expression of HSPA12B may be required for protecting neurons from ischemic insults.
Title: The role of HSPA12B in regulating neuronal apoptosis.

results suggested HSPA12B may be important for host defense in microglia-mediated immune response; understanding the cell signal pathway may provide a novel strategy against inflammatory and immune reaction in neuroinflammtion in CNS
Title: Lipopolysaccharide-evoked HSPA12B expression by activation of MAPK cascade in microglial cells of the spinal cord.

The following Hspa12b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hspa12b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa05943	NM_001107778.1 Latest version!	Rattus norvegicus heat shock protein family A (Hsp70) member 12B (Hspa12b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa26396	XM_006235027.3 Latest version!	Rattus norvegicus heat shock protein 12B (Hspa12b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa26396	XM_006235028.3 Latest version!	Rattus norvegicus heat shock protein 12B (Hspa12b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hspa12b ( NM_001107778.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101248.1 Rattus norvegicus heat shock protein family A (Hsp70) member 12B (Hspa12b), mRNA.

Price & Availability↑

CloneID	ORa05943
Clone ID Related Accession (Same CDS sequence)	NM_001107778.1
Accession Version	NM_001107778.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-01-21
Organism	Rattus norvegicus(Norway rat)
Product	heat shock 70 kDa protein 12B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473949.1. On or before Oct 4, 2007 this sequence version replaced XM_230610.4, XM_001079421.1, XM_001079432.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTTGACTG TCCCAGAAAT GGGCCTTCAA GGGCTGTATA TCAGCTCTAG TCCAGAAAGG 
TCCCCGGTGC CCAGCCCTCC CGGCTCCCCA AGGACCCAGG AAAGCTGTGG CATTGCTCCC 
CTCACGCCTT CACAGTCTCC AAAGCCAGAG GTCCGAGCTC CACAGCGGGC TTCCTTCTCT 
GTGGTTGTGG CCATCGACTT TGGGACCACA TCCAGTGGCT ATGCCTTCAG TTTTGCTACT 
GACCCTGAGG CCATTCACAT GATGAGGAAA TGGGAGGGAG GGGACCCAGG CGTGGCCCAC 
CAGAAGACCC CCACTTGCCT GCTGCTGACC CCAGAAGGCA TCTTCCACAG TTTTGGCTAC 
ACTGCCCGTG ACTACTACCA CGACCTAGAC CCTGAGGAGG CTCGGGACTG GCTCTACTTT 
GAGAAGTTTA AGATGAAGAT CCACAGTGCC ACTGATCTTA CCTTGAAGAC CCAGCTAGAG 
GCAGTAAACG GAAAGAAGAT GCTGGCCCTG GAGGTGTTTG CCCATGCCCT CCGCTTCTTC 
AAGGAACATG CCCTTCAGGA GCTAAGGGAG CAGAGCGAGT GCATGCTTGA GAAGGATGCT 
GTGCGCTGGG TGCTGACAGT GCCTGCCATC TGGAAACAGC CAGCTAAACA GTTCATGAGA 
GAGGCTGCCT ACCTGGCTGG CCTGGTGTCT CGAGAAGATG CAGAAAAACT ACTCATTGCC 
CTGGAGCCTG AGGCTGCCTC GGTCTACTGT CGGAAACTTC GTCTGCACCA GCTCATGGAC 
CTGAGTAGCC GGACTGCAGG TGGTGGGCGC CTGGGTGAGC GGCGGTCCAT TGACTCCAGC 
TTCCGACATG CCCGAGAGCA GCTGCGGAGG TCTCGCCACA GCCGAACATT CCTGGTGGAG 
TCCGGTGTGG GAGAACTGTG GTCAGAGATG CAAGAAGGAG ACCGCTACAT GGTGGCAGAC 
TGTGGGGGTG GCACTGTGGA CCTGACGGTA CACCAACTGG AGCAGCCTCA TGGAACCCTC 
AAGGAGCTGT ACAAGGCTTC TGGCAAGCGG CCCTTATGGT GCAGTAGGGG TGGACCTGGC 
CTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101248.1
CDS	142..1227
Translation	MLTVPEMGLQGLYISSSPERSPVPSPPGSPRTQESCGIAPLTPSQSPKPEVRAPQRASFSVVVAIDFGTTSSGYAFSFATDPEAIHMMRKWEGGDPGVAHQKTPTCLLLTPEGIFHSFGYTARDYYHDLDPEEARDWLYFEKFKMKIHSATDLTLKTQLEAVNGKKMLALEVFAHALRFFKEHALQELREQSECMLEKDAVRWVLTVPAIWKQPAKQFMREAAYLAGLVSREDAEKLLIALEPEAASVYCRKLRLHQLMDLSSRTAGGGRLGERRSIDSSFRHAREQLRRSRHSRTFLVESGVGELWSEMQEGDRYMVADCGGGTVDLTVHQLEQPHGTLKELYKASGKRPLWCSRGGPGL

Target ORF information:

RefSeq Version	NM_001107778.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus heat shock protein family A (Hsp70) member 12B (Hspa12b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107778.1

ORF Insert Sequence:

ATGTTGACTG TCCCAGAAAT GGGCCTTCAA GGGCTGTATA TCAGCTCTAG TCCAGAAAGG 
TCCCCGGTGC CCAGCCCTCC CGGCTCCCCA AGGACCCAGG AAAGCTGTGG CATTGCTCCC 
CTCACGCCTT CACAGTCTCC AAAGCCAGAG GTCCGAGCTC CACAGCGGGC TTCCTTCTCT 
GTGGTTGTGG CCATCGACTT TGGGACCACA TCCAGTGGCT ATGCCTTCAG TTTTGCTACT 
GACCCTGAGG CCATTCACAT GATGAGGAAA TGGGAGGGAG GGGACCCAGG CGTGGCCCAC 
CAGAAGACCC CCACTTGCCT GCTGCTGACC CCAGAAGGCA TCTTCCACAG TTTTGGCTAC 
ACTGCCCGTG ACTACTACCA CGACCTAGAC CCTGAGGAGG CTCGGGACTG GCTCTACTTT 
GAGAAGTTTA AGATGAAGAT CCACAGTGCC ACTGATCTTA CCTTGAAGAC CCAGCTAGAG 
GCAGTAAACG GAAAGAAGAT GCTGGCCCTG GAGGTGTTTG CCCATGCCCT CCGCTTCTTC 
AAGGAACATG CCCTTCAGGA GCTAAGGGAG CAGAGCGAGT GCATGCTTGA GAAGGATGCT 
GTGCGCTGGG TGCTGACAGT GCCTGCCATC TGGAAACAGC CAGCTAAACA GTTCATGAGA 
GAGGCTGCCT ACCTGGCTGG CCTGGTGTCT CGAGAAGATG CAGAAAAACT ACTCATTGCC 
CTGGAGCCTG AGGCTGCCTC GGTCTACTGT CGGAAACTTC GTCTGCACCA GCTCATGGAC 
CTGAGTAGCC GGACTGCAGG TGGTGGGCGC CTGGGTGAGC GGCGGTCCAT TGACTCCAGC 
TTCCGACATG CCCGAGAGCA GCTGCGGAGG TCTCGCCACA GCCGAACATT CCTGGTGGAG 
TCCGGTGTGG GAGAACTGTG GTCAGAGATG CAAGAAGGAG ACCGCTACAT GGTGGCAGAC 
TGTGGGGGTG GCACTGTGGA CCTGACGGTA CACCAACTGG AGCAGCCTCA TGGAACCCTC 
AAGGAGCTGT ACAAGGCTTC TGGCAAGCGG CCCTTATGGT GCAGTAGGGG TGGACCTGGC 
CTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hspa12b ( XM_006235028.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006235090.1 Rattus norvegicus heat shock protein 12B (Hspa12b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa26396
Clone ID Related Accession (Same CDS sequence)	XM_006235028.3 , XM_006235027.3
Accession Version	XM_006235028.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2058bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	heat shock 70 kDa protein 12B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006235028.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACTG TCCCAGAAAT GGGCCTTCAA GGGCTGTATA TCAGCTCTAG TCCAGAAAGG 
TCCCCGGTGC CCAGCCCTCC CGGCTCCCCA AGGACCCAGG AAAGCTGTGG CATTGCTCCC 
CTCACGCCTT CACAGTCTCC AAAGCCAGAG GTCCGAGCTC CACAGCGGGC TTCCTTCTCT 
GTGGTTGTGG CCATCGACTT TGGGACCACA TCCAGTGGCT ATGCCTTCAG TTTTGCTACT 
GACCCTGAGG CCATTCACAT GATGAGGAAA TGGGAGGGAG GGGACCCAGG CGTGGCCCAC 
CAGAAGACCC CCACTTGCCT GCTGCTGACC CCAGAAGGCA TCTTCCACAG TTTTGGCTAC 
ACTGCCCGTG ACTACTACCA CGACCTAGAC CCTGAGGAGG CTCGGGACTG GCTCTACTTT 
GAGAAGTTTA AGATGAAGAT CCACAGTGCC ACTGATCTTA CCTTGAAGAC CCAGCTAGAG 
GCAGTAAACG GAAAGAAGAT GCTGGCCCTG GAGGTGTTTG CCCATGCCCT CCGCTTCTTC 
AAGGAACATG CCCTTCAGGA GCTAAGGGAG CAGAGCGAGT GCATGCTTGA GAAGGATGCT 
GTGCGCTGGG TGCTGACAGT GCCTGCCATC TGGAAACAGC CAGCTAAACA GTTCATGAGA 
GAGGCTGCCT ACCTGGCTGG CCTGGTGTCT CGAGAAGATG CAGAAAAACT ACTCATTGCC 
CTGGAGCCTG AGGCTGCCTC GGTCTACTGT CGGAAACTTC GTCTGCACCA GCTCATGGAC 
CTGAGTAGCC GGACTGCAGG TGGTGGGCGC CTGGGTGAGC GGCGGTCCAT TGACTCCAGC 
TTCCGACATG CCCGAGAGCA GCTGCGGAGG TCTCGCCACA GCCGAACATT CCTGGTGGAG 
TCCGGTGTGG GAGAACTGTG GTCAGAGATG CAAGAAGGAG ACCGCTACAT GGTGGCAGAC 
TGTGGGGGTG GCACTGTGGA CCTGACGGTA CACCAACTGG AGCAGCCTCA TGGAACCCTC 
AAGGAGCTGT ACAAGGCTTC TGGCGGCCCT TATGGTGCAG TAGGGGTGGA CCTGGCCTTT 
GAGCAGCTGC TCTGCCGCAT ATTTGGGGAG GACTTCATCG CCAAGTTCAA AAGGCAACGG 
CCAGCTGCTT GGGTGGATCT AACCATTGCC TTCGAGGCCC GCAAACGCAC CGCAGGCCCG 
CACCGTGCGG GGGCGCTCAA CATTTCGCTT CCCTTCTCTT TCATTGACTT CTACCGCAAG 
CAACGAGGCC ACAATGTGGA GACGGCCCTG CGCAGGAGCA GTGTGAACTT CGTGAAGTGG 
TCTTCACAGG GGATGCTCCG GATGTCCTGT GAAGCTATGA ATGAGCTGTT TCAGCCCACA 
GTCAGCGGGA TCATCCAACA CATAGAGATG CTGTTGGCTA AGCCTGAGGT GCAGGGTGTG 
AAGCTGCTAT TCCTGGTGGG CGGCTTTGCG GAGTCAGCGG TGCTGCAGCA CGCGGTGCAG 
GAAGCTCTAG GCAATCGTGG CCTGCGGGTG GTGGTCCCGC ACGATGTGGG CCTCACCATC 
CTCAAGGGAG CAGTGCTCTT CGGCCAGGCA CCTGGTGTGG TGCGGGTGCG CCGCTCCCCG 
CTCACTTACG GTGTGGGCGT GCTCAATCGT TTTGTGCCTG GCCACCACCC ACCAGAGAAA 
TTGCTGGTTC GGGATGGGCG CCGCTGGTGC ACTGATGTCT TTGAGCGCTT TGTCGCAGCA 
GAGCAGTCGG TGGCCCTAGG AGAGGAGGTG CGGCGCAGCT ACTGTCCCGC GCGCCCCGGC 
CAGCGGCGTG TGCTCATCAA TCTGTACTGC TGCGCTGCGG AGGACGCGCG CTTCATCACT 
GACCCTGGTG TACGCAAGTG TGGTGCGCTC AGCCTGGAGC TTGAGCCTGA AGGCAGCCCA 
GAAAACACGG GCACGTCCCC CAGCCGCCGT GAGATCCGTG CTGCCATGCA GTTTGGAGAT 
ACTGAGATTA AGGTCACTGC TGTGGATGTC AGCACCAATC GCTCAGTGCG GGCAGCCATC 
GACTTTCTTT CCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006235090.1
CDS	182..2239
Translation	MLTVPEMGLQGLYISSSPERSPVPSPPGSPRTQESCGIAPLTPSQSPKPEVRAPQRASFSVVVAIDFGTTSSGYAFSFATDPEAIHMMRKWEGGDPGVAHQKTPTCLLLTPEGIFHSFGYTARDYYHDLDPEEARDWLYFEKFKMKIHSATDLTLKTQLEAVNGKKMLALEVFAHALRFFKEHALQELREQSECMLEKDAVRWVLTVPAIWKQPAKQFMREAAYLAGLVSREDAEKLLIALEPEAASVYCRKLRLHQLMDLSSRTAGGGRLGERRSIDSSFRHAREQLRRSRHSRTFLVESGVGELWSEMQEGDRYMVADCGGGTVDLTVHQLEQPHGTLKELYKASGGPYGAVGVDLAFEQLLCRIFGEDFIAKFKRQRPAAWVDLTIAFEARKRTAGPHRAGALNISLPFSFIDFYRKQRGHNVETALRRSSVNFVKWSSQGMLRMSCEAMNELFQPTVSGIIQHIEMLLAKPEVQGVKLLFLVGGFAESAVLQHAVQEALGNRGLRVVVPHDVGLTILKGAVLFGQAPGVVRVRRSPLTYGVGVLNRFVPGHHPPEKLLVRDGRRWCTDVFERFVAAEQSVALGEEVRRSYCPARPGQRRVLINLYCCAAEDARFITDPGVRKCGALSLELEPEGSPENTGTSPSRREIRAAMQFGDTEIKVTAVDVSTNRSVRAAIDFLSN

Target ORF information:

RefSeq Version	XM_006235028.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus heat shock protein 12B (Hspa12b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006235028.3

ORF Insert Sequence:

ATGTTGACTG TCCCAGAAAT GGGCCTTCAA GGGCTGTATA TCAGCTCTAG TCCAGAAAGG 
TCCCCGGTGC CCAGCCCTCC CGGCTCCCCA AGGACCCAGG AAAGCTGTGG CATTGCTCCC 
CTCACGCCTT CACAGTCTCC AAAGCCAGAG GTCCGAGCTC CACAGCGGGC TTCCTTCTCT 
GTGGTTGTGG CCATCGACTT TGGGACCACA TCCAGTGGCT ATGCCTTCAG TTTTGCTACT 
GACCCTGAGG CCATTCACAT GATGAGGAAA TGGGAGGGAG GGGACCCAGG CGTGGCCCAC 
CAGAAGACCC CCACTTGCCT GCTGCTGACC CCAGAAGGCA TCTTCCACAG TTTTGGCTAC 
ACTGCCCGTG ACTACTACCA CGACCTAGAC CCTGAGGAGG CTCGGGACTG GCTCTACTTT 
GAGAAGTTTA AGATGAAGAT CCACAGTGCC ACTGATCTTA CCTTGAAGAC CCAGCTAGAG 
GCAGTAAACG GAAAGAAGAT GCTGGCCCTG GAGGTGTTTG CCCATGCCCT CCGCTTCTTC 
AAGGAACATG CCCTTCAGGA GCTAAGGGAG CAGAGCGAGT GCATGCTTGA GAAGGATGCT 
GTGCGCTGGG TGCTGACAGT GCCTGCCATC TGGAAACAGC CAGCTAAACA GTTCATGAGA 
GAGGCTGCCT ACCTGGCTGG CCTGGTGTCT CGAGAAGATG CAGAAAAACT ACTCATTGCC 
CTGGAGCCTG AGGCTGCCTC GGTCTACTGT CGGAAACTTC GTCTGCACCA GCTCATGGAC 
CTGAGTAGCC GGACTGCAGG TGGTGGGCGC CTGGGTGAGC GGCGGTCCAT TGACTCCAGC 
TTCCGACATG CCCGAGAGCA GCTGCGGAGG TCTCGCCACA GCCGAACATT CCTGGTGGAG 
TCCGGTGTGG GAGAACTGTG GTCAGAGATG CAAGAAGGAG ACCGCTACAT GGTGGCAGAC 
TGTGGGGGTG GCACTGTGGA CCTGACGGTA CACCAACTGG AGCAGCCTCA TGGAACCCTC 
AAGGAGCTGT ACAAGGCTTC TGGCGGCCCT TATGGTGCAG TAGGGGTGGA CCTGGCCTTT 
GAGCAGCTGC TCTGCCGCAT ATTTGGGGAG GACTTCATCG CCAAGTTCAA AAGGCAACGG 
CCAGCTGCTT GGGTGGATCT AACCATTGCC TTCGAGGCCC GCAAACGCAC CGCAGGCCCG 
CACCGTGCGG GGGCGCTCAA CATTTCGCTT CCCTTCTCTT TCATTGACTT CTACCGCAAG 
CAACGAGGCC ACAATGTGGA GACGGCCCTG CGCAGGAGCA GTGTGAACTT CGTGAAGTGG 
TCTTCACAGG GGATGCTCCG GATGTCCTGT GAAGCTATGA ATGAGCTGTT TCAGCCCACA 
GTCAGCGGGA TCATCCAACA CATAGAGATG CTGTTGGCTA AGCCTGAGGT GCAGGGTGTG 
AAGCTGCTAT TCCTGGTGGG CGGCTTTGCG GAGTCAGCGG TGCTGCAGCA CGCGGTGCAG 
GAAGCTCTAG GCAATCGTGG CCTGCGGGTG GTGGTCCCGC ACGATGTGGG CCTCACCATC 
CTCAAGGGAG CAGTGCTCTT CGGCCAGGCA CCTGGTGTGG TGCGGGTGCG CCGCTCCCCG 
CTCACTTACG GTGTGGGCGT GCTCAATCGT TTTGTGCCTG GCCACCACCC ACCAGAGAAA 
TTGCTGGTTC GGGATGGGCG CCGCTGGTGC ACTGATGTCT TTGAGCGCTT TGTCGCAGCA 
GAGCAGTCGG TGGCCCTAGG AGAGGAGGTG CGGCGCAGCT ACTGTCCCGC GCGCCCCGGC 
CAGCGGCGTG TGCTCATCAA TCTGTACTGC TGCGCTGCGG AGGACGCGCG CTTCATCACT 
GACCCTGGTG TACGCAAGTG TGGTGCGCTC AGCCTGGAGC TTGAGCCTGA AGGCAGCCCA 
GAAAACACGG GCACGTCCCC CAGCCGCCGT GAGATCCGTG CTGCCATGCA GTTTGGAGAT 
ACTGAGATTA AGGTCACTGC TGTGGATGTC AGCACCAATC GCTCAGTGCG GGCAGCCATC 
GACTTTCTTT CCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hspa12b ( XM_006235027.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006235089.1 Rattus norvegicus heat shock protein 12B (Hspa12b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa26396
Clone ID Related Accession (Same CDS sequence)	XM_006235028.3 , XM_006235027.3
Accession Version	XM_006235027.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2058bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	heat shock 70 kDa protein 12B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006235027.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACTG TCCCAGAAAT GGGCCTTCAA GGGCTGTATA TCAGCTCTAG TCCAGAAAGG 
TCCCCGGTGC CCAGCCCTCC CGGCTCCCCA AGGACCCAGG AAAGCTGTGG CATTGCTCCC 
CTCACGCCTT CACAGTCTCC AAAGCCAGAG GTCCGAGCTC CACAGCGGGC TTCCTTCTCT 
GTGGTTGTGG CCATCGACTT TGGGACCACA TCCAGTGGCT ATGCCTTCAG TTTTGCTACT 
GACCCTGAGG CCATTCACAT GATGAGGAAA TGGGAGGGAG GGGACCCAGG CGTGGCCCAC 
CAGAAGACCC CCACTTGCCT GCTGCTGACC CCAGAAGGCA TCTTCCACAG TTTTGGCTAC 
ACTGCCCGTG ACTACTACCA CGACCTAGAC CCTGAGGAGG CTCGGGACTG GCTCTACTTT 
GAGAAGTTTA AGATGAAGAT CCACAGTGCC ACTGATCTTA CCTTGAAGAC CCAGCTAGAG 
GCAGTAAACG GAAAGAAGAT GCTGGCCCTG GAGGTGTTTG CCCATGCCCT CCGCTTCTTC 
AAGGAACATG CCCTTCAGGA GCTAAGGGAG CAGAGCGAGT GCATGCTTGA GAAGGATGCT 
GTGCGCTGGG TGCTGACAGT GCCTGCCATC TGGAAACAGC CAGCTAAACA GTTCATGAGA 
GAGGCTGCCT ACCTGGCTGG CCTGGTGTCT CGAGAAGATG CAGAAAAACT ACTCATTGCC 
CTGGAGCCTG AGGCTGCCTC GGTCTACTGT CGGAAACTTC GTCTGCACCA GCTCATGGAC 
CTGAGTAGCC GGACTGCAGG TGGTGGGCGC CTGGGTGAGC GGCGGTCCAT TGACTCCAGC 
TTCCGACATG CCCGAGAGCA GCTGCGGAGG TCTCGCCACA GCCGAACATT CCTGGTGGAG 
TCCGGTGTGG GAGAACTGTG GTCAGAGATG CAAGAAGGAG ACCGCTACAT GGTGGCAGAC 
TGTGGGGGTG GCACTGTGGA CCTGACGGTA CACCAACTGG AGCAGCCTCA TGGAACCCTC 
AAGGAGCTGT ACAAGGCTTC TGGCGGCCCT TATGGTGCAG TAGGGGTGGA CCTGGCCTTT 
GAGCAGCTGC TCTGCCGCAT ATTTGGGGAG GACTTCATCG CCAAGTTCAA AAGGCAACGG 
CCAGCTGCTT GGGTGGATCT AACCATTGCC TTCGAGGCCC GCAAACGCAC CGCAGGCCCG 
CACCGTGCGG GGGCGCTCAA CATTTCGCTT CCCTTCTCTT TCATTGACTT CTACCGCAAG 
CAACGAGGCC ACAATGTGGA GACGGCCCTG CGCAGGAGCA GTGTGAACTT CGTGAAGTGG 
TCTTCACAGG GGATGCTCCG GATGTCCTGT GAAGCTATGA ATGAGCTGTT TCAGCCCACA 
GTCAGCGGGA TCATCCAACA CATAGAGATG CTGTTGGCTA AGCCTGAGGT GCAGGGTGTG 
AAGCTGCTAT TCCTGGTGGG CGGCTTTGCG GAGTCAGCGG TGCTGCAGCA CGCGGTGCAG 
GAAGCTCTAG GCAATCGTGG CCTGCGGGTG GTGGTCCCGC ACGATGTGGG CCTCACCATC 
CTCAAGGGAG CAGTGCTCTT CGGCCAGGCA CCTGGTGTGG TGCGGGTGCG CCGCTCCCCG 
CTCACTTACG GTGTGGGCGT GCTCAATCGT TTTGTGCCTG GCCACCACCC ACCAGAGAAA 
TTGCTGGTTC GGGATGGGCG CCGCTGGTGC ACTGATGTCT TTGAGCGCTT TGTCGCAGCA 
GAGCAGTCGG TGGCCCTAGG AGAGGAGGTG CGGCGCAGCT ACTGTCCCGC GCGCCCCGGC 
CAGCGGCGTG TGCTCATCAA TCTGTACTGC TGCGCTGCGG AGGACGCGCG CTTCATCACT 
GACCCTGGTG TACGCAAGTG TGGTGCGCTC AGCCTGGAGC TTGAGCCTGA AGGCAGCCCA 
GAAAACACGG GCACGTCCCC CAGCCGCCGT GAGATCCGTG CTGCCATGCA GTTTGGAGAT 
ACTGAGATTA AGGTCACTGC TGTGGATGTC AGCACCAATC GCTCAGTGCG GGCAGCCATC 
GACTTTCTTT CCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006235089.1
CDS	302..2359
Translation	MLTVPEMGLQGLYISSSPERSPVPSPPGSPRTQESCGIAPLTPSQSPKPEVRAPQRASFSVVVAIDFGTTSSGYAFSFATDPEAIHMMRKWEGGDPGVAHQKTPTCLLLTPEGIFHSFGYTARDYYHDLDPEEARDWLYFEKFKMKIHSATDLTLKTQLEAVNGKKMLALEVFAHALRFFKEHALQELREQSECMLEKDAVRWVLTVPAIWKQPAKQFMREAAYLAGLVSREDAEKLLIALEPEAASVYCRKLRLHQLMDLSSRTAGGGRLGERRSIDSSFRHAREQLRRSRHSRTFLVESGVGELWSEMQEGDRYMVADCGGGTVDLTVHQLEQPHGTLKELYKASGGPYGAVGVDLAFEQLLCRIFGEDFIAKFKRQRPAAWVDLTIAFEARKRTAGPHRAGALNISLPFSFIDFYRKQRGHNVETALRRSSVNFVKWSSQGMLRMSCEAMNELFQPTVSGIIQHIEMLLAKPEVQGVKLLFLVGGFAESAVLQHAVQEALGNRGLRVVVPHDVGLTILKGAVLFGQAPGVVRVRRSPLTYGVGVLNRFVPGHHPPEKLLVRDGRRWCTDVFERFVAAEQSVALGEEVRRSYCPARPGQRRVLINLYCCAAEDARFITDPGVRKCGALSLELEPEGSPENTGTSPSRREIRAAMQFGDTEIKVTAVDVSTNRSVRAAIDFLSN

Target ORF information:

RefSeq Version	XM_006235027.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus heat shock protein 12B (Hspa12b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006235027.3

ORF Insert Sequence:

ATGTTGACTG TCCCAGAAAT GGGCCTTCAA GGGCTGTATA TCAGCTCTAG TCCAGAAAGG 
TCCCCGGTGC CCAGCCCTCC CGGCTCCCCA AGGACCCAGG AAAGCTGTGG CATTGCTCCC 
CTCACGCCTT CACAGTCTCC AAAGCCAGAG GTCCGAGCTC CACAGCGGGC TTCCTTCTCT 
GTGGTTGTGG CCATCGACTT TGGGACCACA TCCAGTGGCT ATGCCTTCAG TTTTGCTACT 
GACCCTGAGG CCATTCACAT GATGAGGAAA TGGGAGGGAG GGGACCCAGG CGTGGCCCAC 
CAGAAGACCC CCACTTGCCT GCTGCTGACC CCAGAAGGCA TCTTCCACAG TTTTGGCTAC 
ACTGCCCGTG ACTACTACCA CGACCTAGAC CCTGAGGAGG CTCGGGACTG GCTCTACTTT 
GAGAAGTTTA AGATGAAGAT CCACAGTGCC ACTGATCTTA CCTTGAAGAC CCAGCTAGAG 
GCAGTAAACG GAAAGAAGAT GCTGGCCCTG GAGGTGTTTG CCCATGCCCT CCGCTTCTTC 
AAGGAACATG CCCTTCAGGA GCTAAGGGAG CAGAGCGAGT GCATGCTTGA GAAGGATGCT 
GTGCGCTGGG TGCTGACAGT GCCTGCCATC TGGAAACAGC CAGCTAAACA GTTCATGAGA 
GAGGCTGCCT ACCTGGCTGG CCTGGTGTCT CGAGAAGATG CAGAAAAACT ACTCATTGCC 
CTGGAGCCTG AGGCTGCCTC GGTCTACTGT CGGAAACTTC GTCTGCACCA GCTCATGGAC 
CTGAGTAGCC GGACTGCAGG TGGTGGGCGC CTGGGTGAGC GGCGGTCCAT TGACTCCAGC 
TTCCGACATG CCCGAGAGCA GCTGCGGAGG TCTCGCCACA GCCGAACATT CCTGGTGGAG 
TCCGGTGTGG GAGAACTGTG GTCAGAGATG CAAGAAGGAG ACCGCTACAT GGTGGCAGAC 
TGTGGGGGTG GCACTGTGGA CCTGACGGTA CACCAACTGG AGCAGCCTCA TGGAACCCTC 
AAGGAGCTGT ACAAGGCTTC TGGCGGCCCT TATGGTGCAG TAGGGGTGGA CCTGGCCTTT 
GAGCAGCTGC TCTGCCGCAT ATTTGGGGAG GACTTCATCG CCAAGTTCAA AAGGCAACGG 
CCAGCTGCTT GGGTGGATCT AACCATTGCC TTCGAGGCCC GCAAACGCAC CGCAGGCCCG 
CACCGTGCGG GGGCGCTCAA CATTTCGCTT CCCTTCTCTT TCATTGACTT CTACCGCAAG 
CAACGAGGCC ACAATGTGGA GACGGCCCTG CGCAGGAGCA GTGTGAACTT CGTGAAGTGG 
TCTTCACAGG GGATGCTCCG GATGTCCTGT GAAGCTATGA ATGAGCTGTT TCAGCCCACA 
GTCAGCGGGA TCATCCAACA CATAGAGATG CTGTTGGCTA AGCCTGAGGT GCAGGGTGTG 
AAGCTGCTAT TCCTGGTGGG CGGCTTTGCG GAGTCAGCGG TGCTGCAGCA CGCGGTGCAG 
GAAGCTCTAG GCAATCGTGG CCTGCGGGTG GTGGTCCCGC ACGATGTGGG CCTCACCATC 
CTCAAGGGAG CAGTGCTCTT CGGCCAGGCA CCTGGTGTGG TGCGGGTGCG CCGCTCCCCG 
CTCACTTACG GTGTGGGCGT GCTCAATCGT TTTGTGCCTG GCCACCACCC ACCAGAGAAA 
TTGCTGGTTC GGGATGGGCG CCGCTGGTGC ACTGATGTCT TTGAGCGCTT TGTCGCAGCA 
GAGCAGTCGG TGGCCCTAGG AGAGGAGGTG CGGCGCAGCT ACTGTCCCGC GCGCCCCGGC 
CAGCGGCGTG TGCTCATCAA TCTGTACTGC TGCGCTGCGG AGGACGCGCG CTTCATCACT 
GACCCTGGTG TACGCAAGTG TGGTGCGCTC AGCCTGGAGC TTGAGCCTGA AGGCAGCCCA 
GAAAACACGG GCACGTCCCC CAGCCGCCGT GAGATCCGTG CTGCCATGCA GTTTGGAGAT 
ACTGAGATTA AGGTCACTGC TGTGGATGTC AGCACCAATC GCTCAGTGCG GGCAGCCATC 
GACTTTCTTT CCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Regulation of A-Kinase-Anchoring Protein 12 by Heat Shock Protein A12B to Prevent Ventricular Dysfunction Following Acute Myocardial Infarction in Diabetic Rats.
Journal of cardiovascular translational research10(2)209-220(2017 Apr)
Selvaraju V,Suresh SC,Thirunavukkarasu M,Mannu J,Foye JLC,Mathur PP,Palesty JA,Sanchez JA,McFadden DW,Maulik N

Expression of HSPA12B in acute cardiac allograft rejection in rats.
Pathology, research and practice211(1)20-6(2015 Jan)
Shi J,Yang D,Cong X,Li Y,Yang X,Liu Y

The role of HSPA12B in regulating neuronal apoptosis.
Neurochemical research38(2)311-20(2013 Feb)
Kang L,Zhang G,Yan Y,Ke K,Wu X,Gao Y,Li J,Zhu L,Wu Q,Zhou Z

Lipopolysaccharide-evoked HSPA12B expression by activation of MAPK cascade in microglial cells of the spinal cord.
Journal of the neurological sciences294(1-2)29-37(2010 Jul)
Cui Z,Wang P,Sun L,Liu H,Yang J,Li X,Kang L,Huang Y,Shen A,Cheng C

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Hspa12b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム