Pinx1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pinx1
Entrez Gene ID	305963
Full Name	PIN2/TERF1 interacting, telomerase inhibitor 1
Synonyms	RGD1566025
General protein information	Preferred Names PIN2/TERF1 interacting, telomerase inhibitor 1 Names PIN2/TERF1-interacting telomerase inhibitor 1 PIN2-interacting protein 1 Pin2-interacting protein X1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001083337.1	NP_001076806.1	PIN2/TERF1-interacting telomerase inhibitor 1
XM_006252181.3	XP_006252243.1	PIN2/TERF1-interacting telomerase inhibitor 1 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	PINX1	NP_060354.4
	PINX1	XP_001089816.1
Rattus norvegicus (Norway rat)	Pinx1	NP_001076806.1
Canis lupus familiaris (dog)	PINX1	XP_003639935.1
Bos taurus (cattle)	PINX1	NP_001029725.1
Mus musculus (house mouse)	Pinx1	NP_082504.1

Gene Ontology
Bibliography

Related articles in PubMed

PinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual roles.
Yoo JE, Park YN, Oh BK
The Journal of biological chemistry289(10)6886-98(2014 Mar)

PinX1 is involved in telomerase recruitment and regulates telomerase function by mediating its localization.
Cheung DH, Kung HF, Huang JJ, Shaw PC
FEBS letters586(19)3166-71(2012 Sep)

Telomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongation.
Soohoo CY, Shi R, Lee TH, Huang P, Lu KP, Zhou XZ
The Journal of biological chemistry286(5)3894-906(2011 Feb)

PinX1 is recruited to the mitotic chromosome periphery by Nucleolin and facilitates chromosome congression.
Li N, Yuan K, Yan F, Huo Y, Zhu T, Liu X, Guo Z, Yao X
Biochemical and biophysical research communications384(1)76-81(2009 Jun)

Human PinX1 mediates TRF1 accumulation in nucleolus and enhances TRF1 binding to telomeres.
Yoo JE, Oh BK, Park YN
Journal of molecular biology388(5)928-40(2009 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pinx1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pinx1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10906	NM_001083337.1 Latest version!	Rattus norvegicus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa36795	XM_006252181.3 Latest version!	Rattus norvegicus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pinx1 ( NM_001083337.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001076806.1 Rattus norvegicus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), mRNA.

Price & Availability↑

CloneID	ORa10906
Clone ID Related Accession (Same CDS sequence)	NM_001083337.1
Accession Version	NM_001083337.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 996bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Rattus norvegicus(Norway rat)
Product	PIN2/TERF1-interacting telomerase inhibitor 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EF446165.1. On or before Mar 25, 2007 this sequence version replaced XM_224282.4, XM_001065542.1. ##Evidence-Data-START## Transcript exon combination :: EF446165.1, BC158553.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCGATGC TAGCGGAGCG TCGGCGGAAG CAGAAATGGG CTGTGGATCC CAGAAATACT 
GCGTGGAGTA ATGATGATTC CAAGTTTGGC CAGAAGATGC TTGAGAAGAT GGGGTGGTCT 
AAAGGAAAGG GTTTGGGGGC TCAGGAGCAA GGAGCCACAG AACATATTAA AGTTAAAGTT 
AAAAATAACC ACCTGGGACT TGGAGCTACA AACAATAATG AAGACAACTG GATTGCTCAC 
CAGGATGACT TCAACCAGCT TTTGGCAGCA CTCAACACTT GCCATGGTCA GGAAACAGCA 
GACTCCTCAG ACAACAAGGA AAAGAAATCT TTTAGCCTTG AAGAAAAATC CAAAATCTCC 
AAAAACCGGG TTCATTATAT GAAATTCACC AAAGGGAAGG ACCTGTCCTC TCGGAGCGAA 
ACCGACCTGG ATTGTATTTT TGGAAAAAGG AGGAACAAGA AGCTTGCTCA GGACGGCTGC 
AGCAACTCCA CTGCGGATGA GGCGGACACC TCCCTGACCA CGACCACAAC CACAACCAGT 
GCCTTCACCA TCCAGGAATA TTTTGCCAAG AGGATGGCCC AGTTAAAGAG CAAGTCACAG 
GCCGCAGCTC CAGGGTCTGA CCTTTCAGAG ACCCCCATTG AATGGAAAAA GGGAAAGAAA 
AAAACCAAAG AGGCAGCAGG CACAGATATA GAGAACTCTC CCCAACACAA GGCCAAGCGG 
CATAAAAAGA AGAAGCGAGT GGAAGCAGAG AGGGGGCCTG CGGCCAAGAA GAGAGACCAA 
GTCGAGCTGC AGCCTGGAGG CCCCAGTGGG GACGAGTGTT CCGACGCCTC TGTGGAGGCT 
GCAGAGGATC GTGTGCAGAC ACCAGACACC CAGGATGATG TCCCAAAGCC CAGGAAGAGG 
AGAGCAAAGA AGACGCTGCA GAGGCCAGGA GGAGTGGCAG TAGACACTGC ACCGGACAGC 
GCACCAGTGA AGAAGAAGAA GAAAGTTTCC AGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001076806.1
CDS	1..996
Translation	MSMLAERRRKQKWAVDPRNTAWSNDDSKFGQKMLEKMGWSKGKGLGAQEQGATEHIKVKVKNNHLGLGATNNNEDNWIAHQDDFNQLLAALNTCHGQETADSSDNKEKKSFSLEEKSKISKNRVHYMKFTKGKDLSSRSETDLDCIFGKRRNKKLAQDGCSNSTADEADTSLTTTTTTTSAFTIQEYFAKRMAQLKSKSQAAAPGSDLSETPIEWKKGKKKTKEAAGTDIENSPQHKAKRHKKKKRVEAERGPAAKKRDQVELQPGGPSGDECSDASVEAAEDRVQTPDTQDDVPKPRKRRAKKTLQRPGGVAVDTAPDSAPVKKKKKVSR

Target ORF information:

RefSeq Version	NM_001083337.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001083337.1

ORF Insert Sequence:

ATGTCGATGC TAGCGGAGCG TCGGCGGAAG CAGAAATGGG CTGTGGATCC CAGAAATACT 
GCGTGGAGTA ATGATGATTC CAAGTTTGGC CAGAAGATGC TTGAGAAGAT GGGGTGGTCT 
AAAGGAAAGG GTTTGGGGGC TCAGGAGCAA GGAGCCACAG AACATATTAA AGTTAAAGTT 
AAAAATAACC ACCTGGGACT TGGAGCTACA AACAATAATG AAGACAACTG GATTGCTCAC 
CAGGATGACT TCAACCAGCT TTTGGCAGCA CTCAACACTT GCCATGGTCA GGAAACAGCA 
GACTCCTCAG ACAACAAGGA AAAGAAATCT TTTAGCCTTG AAGAAAAATC CAAAATCTCC 
AAAAACCGGG TTCATTATAT GAAATTCACC AAAGGGAAGG ACCTGTCCTC TCGGAGCGAA 
ACCGACCTGG ATTGTATTTT TGGAAAAAGG AGGAACAAGA AGCTTGCTCA GGACGGCTGC 
AGCAACTCCA CTGCGGATGA GGCGGACACC TCCCTGACCA CGACCACAAC CACAACCAGT 
GCCTTCACCA TCCAGGAATA TTTTGCCAAG AGGATGGCCC AGTTAAAGAG CAAGTCACAG 
GCCGCAGCTC CAGGGTCTGA CCTTTCAGAG ACCCCCATTG AATGGAAAAA GGGAAAGAAA 
AAAACCAAAG AGGCAGCAGG CACAGATATA GAGAACTCTC CCCAACACAA GGCCAAGCGG 
CATAAAAAGA AGAAGCGAGT GGAAGCAGAG AGGGGGCCTG CGGCCAAGAA GAGAGACCAA 
GTCGAGCTGC AGCCTGGAGG CCCCAGTGGG GACGAGTGTT CCGACGCCTC TGTGGAGGCT 
GCAGAGGATC GTGTGCAGAC ACCAGACACC CAGGATGATG TCCCAAAGCC CAGGAAGAGG 
AGAGCAAAGA AGACGCTGCA GAGGCCAGGA GGAGTGGCAG TAGACACTGC ACCGGACAGC 
GCACCAGTGA AGAAGAAGAA GAAAGTTTCC AGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pinx1 ( XM_006252181.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252243.1 Rattus norvegicus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa36795
Clone ID Related Accession (Same CDS sequence)	XM_006252181.3
Accession Version	XM_006252181.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1101bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	PIN2/TERF1-interacting telomerase inhibitor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252181.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGCCAG TCATCAGGAG GCAGAGTCCG CTCTCCCGCT CTCTCACCCT CAGGGATGGC 
TCACCCATGC CTTTGTCATC TGGGCCAGCT CCACTGTGCT GCCTTGGGTT TTCTTATCAG 
AAAGGTCGGC GGAAGCAGAA ATGGGCTGTG GATCCCAGAA ATACTGCGTG GAGTAATGAT 
GATTCCAAGT TTGGCCAGAA GATGCTTGAG AAGATGGGGT GGTCTAAAGG AAAGGGTTTG 
GGGGCTCAGG AGCAAGGAGC CACAGAACAT ATTAAAGTTA AAGTTAAAAA TAACCACCTG 
GGACTTGGAG CTACAAACAA TAATGAAGAC AACTGGATTG CTCACCAGGA TGACTTCAAC 
CAGCTTTTGG CAGCACTCAA CACTTGCCAT GGTCAGGAAA CAGCAGATTC CTCAGACAAC 
AAGGAAAAGA AATCTTTTAG CCTTGAAGAA AAATCCAAAA TCTCCAAAAA CCGGGTTCAT 
TATATGAAAT TCACCAAAGG GAAGGACCTG TCCTCTCGGA GCGAAACCGA CCTGGATTGT 
ATTTTTGGAA AAAGGAGGAA CAAGAAGCTT GCTCAGGACG GCTGCAGCAA CTCCACTGCG 
GATGAGGCGG ACACCTCCCT GACCACGACC ACAACCACAA CCAGTGCCTT CACCATCCAG 
GAATATTTTG CCAAGAGGAT GGCCCAGTTA AAGAGCAAGT CACAGGCCGC AGCTCCAGGG 
TCTGACCTTT CAGAGACCCC CATTGAATGG AAAAAGGGAA AGAAAAAAAC CAAAGAGGCA 
GCAGGCACAG ATATAGAGAA CTCTCCCCAA CACAAGGCCA AGCGGCATAA AAAGAAGAAG 
CGAGTGGAAG CAGAGAGGGG GCCTGCGGCC AAGAAGAGAG ACCAAGTCGA GCTGCAGCCT 
GGAGGCCCCA GTGGGGACGA GTGTTCCGAC GCCTCTGTGG AGGCTGCAGA GGATCGTGTG 
CAGACACCAG ACACCCAGGA TGATGTCCCA AAGCCCAGGA AGAGGAGAGC AAAGAAGACG 
CTGCAGAGGC CAGGAGGAGT GGCAGTAGAC ACTGCACCGG ACAGCGCACC AGTGAAGAAG 
AAGAAGAAAG TTTCCAGATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252243.1
CDS	816..1916
Translation	MPPVIRRQSPLSRSLTLRDGSPMPLSSGPAPLCCLGFSYQKGRRKQKWAVDPRNTAWSNDDSKFGQKMLEKMGWSKGKGLGAQEQGATEHIKVKVKNNHLGLGATNNNEDNWIAHQDDFNQLLAALNTCHGQETADSSDNKEKKSFSLEEKSKISKNRVHYMKFTKGKDLSSRSETDLDCIFGKRRNKKLAQDGCSNSTADEADTSLTTTTTTTSAFTIQEYFAKRMAQLKSKSQAAAPGSDLSETPIEWKKGKKKTKEAAGTDIENSPQHKAKRHKKKKRVEAERGPAAKKRDQVELQPGGPSGDECSDASVEAAEDRVQTPDTQDDVPKPRKRRAKKTLQRPGGVAVDTAPDSAPVKKKKKVSR

Target ORF information:

RefSeq Version	XM_006252181.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252181.3

ORF Insert Sequence:

ATGCCGCCAG TCATCAGGAG GCAGAGTCCG CTCTCCCGCT CTCTCACCCT CAGGGATGGC 
TCACCCATGC CTTTGTCATC TGGGCCAGCT CCACTGTGCT GCCTTGGGTT TTCTTATCAG 
AAAGGTCGGC GGAAGCAGAA ATGGGCTGTG GATCCCAGAA ATACTGCGTG GAGTAATGAT 
GATTCCAAGT TTGGCCAGAA GATGCTTGAG AAGATGGGGT GGTCTAAAGG AAAGGGTTTG 
GGGGCTCAGG AGCAAGGAGC CACAGAACAT ATTAAAGTTA AAGTTAAAAA TAACCACCTG 
GGACTTGGAG CTACAAACAA TAATGAAGAC AACTGGATTG CTCACCAGGA TGACTTCAAC 
CAGCTTTTGG CAGCACTCAA CACTTGCCAT GGTCAGGAAA CAGCAGATTC CTCAGACAAC 
AAGGAAAAGA AATCTTTTAG CCTTGAAGAA AAATCCAAAA TCTCCAAAAA CCGGGTTCAT 
TATATGAAAT TCACCAAAGG GAAGGACCTG TCCTCTCGGA GCGAAACCGA CCTGGATTGT 
ATTTTTGGAA AAAGGAGGAA CAAGAAGCTT GCTCAGGACG GCTGCAGCAA CTCCACTGCG 
GATGAGGCGG ACACCTCCCT GACCACGACC ACAACCACAA CCAGTGCCTT CACCATCCAG 
GAATATTTTG CCAAGAGGAT GGCCCAGTTA AAGAGCAAGT CACAGGCCGC AGCTCCAGGG 
TCTGACCTTT CAGAGACCCC CATTGAATGG AAAAAGGGAA AGAAAAAAAC CAAAGAGGCA 
GCAGGCACAG ATATAGAGAA CTCTCCCCAA CACAAGGCCA AGCGGCATAA AAAGAAGAAG 
CGAGTGGAAG CAGAGAGGGG GCCTGCGGCC AAGAAGAGAG ACCAAGTCGA GCTGCAGCCT 
GGAGGCCCCA GTGGGGACGA GTGTTCCGAC GCCTCTGTGG AGGCTGCAGA GGATCGTGTG 
CAGACACCAG ACACCCAGGA TGATGTCCCA AAGCCCAGGA AGAGGAGAGC AAAGAAGACG 
CTGCAGAGGC CAGGAGGAGT GGCAGTAGAC ACTGCACCGG ACAGCGCACC AGTGAAGAAG 
AAGAAGAAAG TTTCCAGATA G