Dapk2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dapk2
Entrez Gene ID	300799
Full Name	death-associated protein kinase 2
General protein information	Preferred Names death-associated protein kinase 2 Names death-associated protein kinase 2 death-associated kinase 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q24

mRNA and Protein(s)

mRNA	Protein	Name
XM_008766241.2	XP_008764463.1	death-associated protein kinase 2 isoform X1
NM_001013109.1	NP_001013127.1	death-associated protein kinase 2

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Overexpression of microRNA-133a inhibits ischemia-reperfusion-induced cardiomyocyte apoptosis by targeting DAPK2.
Li S, Xiao FY, Shan PR, Su L, Chen DL, Ding JY, Wang ZQ
Journal of human genetics60(11)709-16(2015 Nov)

DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants.
Geering B, Stoeckle C, Rozman S, Oberson K, Benarafa C, Simon HU
Journal of leukocyte biology95(2)293-303(2014 Feb)

Down-regulation of death-associated protein kinase-2 is required for beta-catenin-induced anoikis resistance of malignant epithelial cells.
Li H, Ray G, Yoo BH, Erdogan M, Rosen KV
The Journal of biological chemistry284(4)2012-22(2009 Jan)

Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding.
Shani G, Henis-Korenblit S, Jona G, Gileadi O, Eisenstein M, Ziv T, Admon A, Kimchi A
The EMBO journal20(5)1099-113(2001 Mar)

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis.
Inbal B, Shani G, Cohen O, Kissil JL, Kimchi A
Molecular and cellular biology20(3)1044-54(2000 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MiR-133a overexpression may inhibit I/R injury-mediated cardiomyocyte apoptosis by targeting DAPK2, leading to reduced DAPK2 protein.
Title: Overexpression of microRNA-133a inhibits ischemia-reperfusion-induced cardiomyocyte apoptosis by targeting DAPK2.

The following Dapk2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dapk2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03415	NM_001013109.1 Latest version!	Rattus norvegicus death-associated protein kinase 2 (Dapk2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa45752	XM_008766241.2 Latest version!	Rattus norvegicus death-associated protein kinase 2 (Dapk2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dapk2 ( NM_001013109.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001013127.1 Rattus norvegicus death-associated protein kinase 2 (Dapk2), mRNA.

Price & Availability↑

CloneID	ORa03415
Clone ID Related Accession (Same CDS sequence)	NM_001013109.1
Accession Version	NM_001013109.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-26
Organism	Rattus norvegicus(Norway rat)
Product	death-associated protein kinase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC091410.1. On Mar 26, 2005 this sequence version replaced XM_217177.1. ##Evidence-Data-START## Transcript exon combination :: BC091410.1, DN947798.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689596, SAMEA2689597 [ECO:0000348] ##Evidence-Data-END##

ATGTTGTTAG ACAAGAATAT CCCCATTCCA CACATCAAGC TGATTGACTT TGGCTTGGCT 
CACGAAATAG AAGATGGAGT TGAATTTAAA AACATTTTTG GGACACCTGA ATTTGTTGCT 
CCAGAAATCG TGAACTATGA GCCACTGGGA CTGGAGGCAG ACATGTGGAG CATCGGAGTC 
ATCACCTACA TCCTTCTAAG TGGAGCATCC CCCTTCCTGG GAGACACAAA GCAAGAAACC 
CTGGCAAACA TCACTGCTGT GAGTTACGAC TTTGACGAGG AATTCTTCAG CCAGACCAGT 
GAGCTGGCCA AGGACTTCAT TCGGAAGCTT CTTGTGAAGG AGACCCGGAA ACGGCTTACC 
ATCCAAGAGG CTCTCAGGCA TCCCTGGATC ATGCCAGTGG ACAACCAGCA AGCCATGGTG 
CGCAGAGAGT CTGTGGTCAA CCTGGAGAAC TTTAAGAAGC AGTATGTCCG CAGGCGGTGG 
AAGCTGTCCT TCAGCATCGT CTCCCTGTGC AACCACCTCA CTCGCTCCCT GATGAAGAAG 
GTGCACTTGA GGACAAGTGA GGACCTGAGG AACTGCGAGA GTGACACGGA GGAGAACATT 
GCCAGGAGGA AAGCCCTTCA CCCCCGGAGG AGGAGCAGTA CCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013127.1
CDS	99..746
Translation	MLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWIMPVDNQQAMVRRESVVNLENFKKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRTSEDLRNCESDTEENIARRKALHPRRRSSTS

Target ORF information:

RefSeq Version	NM_001013109.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus death-associated protein kinase 2 (Dapk2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013109.1

ORF Insert Sequence:

ATGTTGTTAG ACAAGAATAT CCCCATTCCA CACATCAAGC TGATTGACTT TGGCTTGGCT 
CACGAAATAG AAGATGGAGT TGAATTTAAA AACATTTTTG GGACACCTGA ATTTGTTGCT 
CCAGAAATCG TGAACTATGA GCCACTGGGA CTGGAGGCAG ACATGTGGAG CATCGGAGTC 
ATCACCTACA TCCTTCTAAG TGGAGCATCC CCCTTCCTGG GAGACACAAA GCAAGAAACC 
CTGGCAAACA TCACTGCTGT GAGTTACGAC TTTGACGAGG AATTCTTCAG CCAGACCAGT 
GAGCTGGCCA AGGACTTCAT TCGGAAGCTT CTTGTGAAGG AGACCCGGAA ACGGCTTACC 
ATCCAAGAGG CTCTCAGGCA TCCCTGGATC ATGCCAGTGG ACAACCAGCA AGCCATGGTG 
CGCAGAGAGT CTGTGGTCAA CCTGGAGAAC TTTAAGAAGC AGTATGTCCG CAGGCGGTGG 
AAGCTGTCCT TCAGCATCGT CTCCCTGTGC AACCACCTCA CTCGCTCCCT GATGAAGAAG 
GTGCACTTGA GGACAAGTGA GGACCTGAGG AACTGCGAGA GTGACACGGA GGAGAACATT 
GCCAGGAGGA AAGCCCTTCA CCCCCGGAGG AGGAGCAGTA CCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dapk2 ( XM_008766241.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008764463.1 Rattus norvegicus death-associated protein kinase 2 (Dapk2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa45752
Clone ID Related Accession (Same CDS sequence)	XM_008766241.2
Accession Version	XM_008766241.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1458bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	death-associated protein kinase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008766241.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGAGTC CAAATATGGA GACATTCAAA CAGCAGAAGG TGGAGGACTT CTATGACATC 
GGAGAGGAGC TGGGCAGTGG CCAGTTCGCC ATCGTGAGGA AGTGCCGGGA GCAGAGCACG 
GGGCTAGAGT ACGCAGCCAA ATTCATCAAG AAGAGGCAGA GCCGGGCCAG CCGTCGGGGC 
GTGTGCCGGG AGGAAATCGA GCGGGAGGTG AGCATCCTGC GGCAGGTGCT GCACCCCAAC 
ATCATCACGC TGCACGACGT CTATGAGAAC CGCACCGATG TGGTGCTCAT CCTTGAGCTA 
GTTTCCGGAG GAGAACTGTT CGATTTCTTG GCCCAGAAGG AGTCGTTAAG TGAGGAGGAA 
GCCACCAGCT TCATTAAGCA GATCCTGGAT GGGGTGAATT ACCTTCATAC AAAGAAAATT 
GCTCACTTTG ATCTCAAGCC AGAAAACATT ATGTTGTTAG ACAAGAATAT CCCCATTCCA 
CACATCAAGC TGATTGACTT TGGCTTGGCT CACGAAATAG AAGATGGAGT TGAATTTAAA 
AACATTTTTG GGACACCTGA ATTTGTTGCT CCAGAAATCG TGAACTATGA GCCACTGGGA 
CTGGAGGCAG ACATGTGGAG CATCGGAGTC ATCACCTACA TCCTTCTAAG TGGAGCATCC 
CCCTTCCTGG GAGACACAAA GCAAGAAACC CTGGCAAACA TCACTGCTGT GAGTTACGAC 
TTTGACGAGG AATTCTTCAG CCAGACCAGT GAGCTGGCCA AGGACTTCAT TCGGAAGCTT 
CTTGTGAAGG AGACCCGGAA ACGGCTTACC ATCCAAGAGG CTCTCAGGCA TCCCTGGATC 
ATGTCAAAAG GAGAAGCCAG CGTCCCTGAG CAGTGGAAGA CACAACCTGC CCAGCTGAAG 
ACCAAACGCC TAAGAGAGTA TACCCTCAAA TGCCACTCCA GCATGCCCCC CAACAACACT 
TATGTCAACT TTGAACGTTT TGCTCACGTA GTAGAGGATG TGGCTCGGGT AGACGAGGGA 
TGCCATGCCC TCGCAGGAGC CCATGATACC CTGCAGGATG ATGTGGAGTC TTTGGTCTCC 
ATCTACAATG AGAAGGAGGC TTGGTACCGA GAGGAGAACG AGAATGCCCG TCATAACCTG 
TCCCAGCTCA AGTATGAGTT CCGCAAGGTG GAGTCCCTGA AGAAGCTTCT GAGAGAAGAC 
ATCCAGGCCG CAGGGGCCAG CCTTGGAGGT GTGGCCAGGA AGCTAGACCA TCTGCAGGTG 
CAGTTTGAGA CTCTGAGGCA GCAGCTGTCA GCAGACATTC AGTGGATGCA GGAAATGGCG 
GGCATACTCC AGCTGGAGAG TGGGAACACT GACGGCCACG CCTTGGGCTC CGTGTTCCAC 
CGGGACACCA GTGAGTCCCT ACCAGAGCTG CTCAACAGAT CACACACGGA GGGGATCCTG 
GCCGGCTTGA ATCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008764463.1
CDS	134..1591
Translation	MRSPNMETFKQQKVEDFYDIGEELGSGQFAIVRKCREQSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWIMSKGEASVPEQWKTQPAQLKTKRLREYTLKCHSSMPPNNTYVNFERFAHVVEDVARVDEGCHALAGAHDTLQDDVESLVSIYNEKEAWYREENENARHNLSQLKYEFRKVESLKKLLREDIQAAGASLGGVARKLDHLQVQFETLRQQLSADIQWMQEMAGILQLESGNTDGHALGSVFHRDTSESLPELLNRSHTEGILAGLNL

Target ORF information:

RefSeq Version	XM_008766241.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus death-associated protein kinase 2 (Dapk2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008766241.2

ORF Insert Sequence:

ATGAGGAGTC CAAATATGGA GACATTCAAA CAGCAGAAGG TGGAGGACTT CTATGACATC 
GGAGAGGAGC TGGGCAGTGG CCAGTTCGCC ATCGTGAGGA AGTGCCGGGA GCAGAGCACG 
GGGCTAGAGT ACGCAGCCAA ATTCATCAAG AAGAGGCAGA GCCGGGCCAG CCGTCGGGGC 
GTGTGCCGGG AGGAAATCGA GCGGGAGGTG AGCATCCTGC GGCAGGTGCT GCACCCCAAC 
ATCATCACGC TGCACGACGT CTATGAGAAC CGCACCGATG TGGTGCTCAT CCTTGAGCTA 
GTTTCCGGAG GAGAACTGTT CGATTTCTTG GCCCAGAAGG AGTCGTTAAG TGAGGAGGAA 
GCCACCAGCT TCATTAAGCA GATCCTGGAT GGGGTGAATT ACCTTCATAC AAAGAAAATT 
GCTCACTTTG ATCTCAAGCC AGAAAACATT ATGTTGTTAG ACAAGAATAT CCCCATTCCA 
CACATCAAGC TGATTGACTT TGGCTTGGCT CACGAAATAG AAGATGGAGT TGAATTTAAA 
AACATTTTTG GGACACCTGA ATTTGTTGCT CCAGAAATCG TGAACTATGA GCCACTGGGA 
CTGGAGGCAG ACATGTGGAG CATCGGAGTC ATCACCTACA TCCTTCTAAG TGGAGCATCC 
CCCTTCCTGG GAGACACAAA GCAAGAAACC CTGGCAAACA TCACTGCTGT GAGTTACGAC 
TTTGACGAGG AATTCTTCAG CCAGACCAGT GAGCTGGCCA AGGACTTCAT TCGGAAGCTT 
CTTGTGAAGG AGACCCGGAA ACGGCTTACC ATCCAAGAGG CTCTCAGGCA TCCCTGGATC 
ATGTCAAAAG GAGAAGCCAG CGTCCCTGAG CAGTGGAAGA CACAACCTGC CCAGCTGAAG 
ACCAAACGCC TAAGAGAGTA TACCCTCAAA TGCCACTCCA GCATGCCCCC CAACAACACT 
TATGTCAACT TTGAACGTTT TGCTCACGTA GTAGAGGATG TGGCTCGGGT AGACGAGGGA 
TGCCATGCCC TCGCAGGAGC CCATGATACC CTGCAGGATG ATGTGGAGTC TTTGGTCTCC 
ATCTACAATG AGAAGGAGGC TTGGTACCGA GAGGAGAACG AGAATGCCCG TCATAACCTG 
TCCCAGCTCA AGTATGAGTT CCGCAAGGTG GAGTCCCTGA AGAAGCTTCT GAGAGAAGAC 
ATCCAGGCCG CAGGGGCCAG CCTTGGAGGT GTGGCCAGGA AGCTAGACCA TCTGCAGGTG 
CAGTTTGAGA CTCTGAGGCA GCAGCTGTCA GCAGACATTC AGTGGATGCA GGAAATGGCG 
GGCATACTCC AGCTGGAGAG TGGGAACACT GACGGCCACG CCTTGGGCTC CGTGTTCCAC 
CGGGACACCA GTGAGTCCCT ACCAGAGCTG CTCAACAGAT CACACACGGA GGGGATCCTG 
GCCGGCTTGA ATCTCTGA