Mgst2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mgst2
Entrez Gene ID	295037
Full Name	microsomal glutathione S-transferase 2
General protein information	Preferred Names microsomal glutathione S-transferase 2 Names microsomal glutathione S-transferase 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q26

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106430.1	NP_001099900.1	microsomal glutathione S-transferase 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	MGST2	NP_001069850.1
Gallus gallus (chicken)	MGST2	XP_001234230.1
Xenopus tropicalis (tropical clawed frog)	LOC101731146	XP_004911179.1
Homo sapiens (human)	MGST2	NP_002404.1
	MGST2	XP_001088512.1
Pan troglodytes (chimpanzee)	MGST2	XP_003310520.1
Mus musculus (house mouse)	Mgst2	NP_778160.2
Rattus norvegicus (Norway rat)	Mgst2	NP_001099900.1
Danio rerio (zebrafish)	mgst2	NP_001038767.1
Canis lupus familiaris (dog)	MGST2	XP_005631834.1
Xenopus tropicalis (tropical clawed frog)	LOC100127860	NP_001106626.1

Gene Ontology
Bibliography

Related articles in PubMed

Catalytic characterization of human microsomal glutathione S-transferase 2: identification of rate-limiting steps.
Ahmad S, Niegowski D, Wetterholm A, Haeggstr?m JZ, Morgenstern R, Rinaldo-Matthis A
Biochemistry52(10)1755-64(2013 Mar)

Enhanced expressions and activations of leukotriene C4 synthesis enzymes in D-galactosamine/lipopolysaccharide-induced rat fulminant hepatic failure model.
Ma KF, Yang HY, Chen Z, Qi LY, Zhu DY, Lou YJ
World journal of gastroenterology14(17)2748-56(2008 May)

Sodium nitroprusside regulates mRNA expressions of LTC4 synthesis enzymes in hepatic ischemia/reperfusion injury rats via NF-kappaB signaling pathway.
Yang SL, Chen LJ, Kong Y, Xu D, Lou YJ
Pharmacology80(1)11-20(2007)

Molecular and catalytic properties of three rat leukotriene C(4) synthase homologs.
Schr?der O, Sj?str?m M, Qiu H, Stein J, Jakobsson PJ, Haeggstr?m JZ
Biochemical and biophysical research communications312(2)271-6(2003 Dec)

The role of glutathione-S-transferase in anti-cancer drug resistance.
Townsend DM, Tew KD
Oncogene22(47)7369-75(2003 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Liver mGST2 was up-regulated in rat model of fulminant hepatic failure.
Title: Enhanced expressions and activations of leukotriene C4 synthesis enzymes in D-galactosamine/lipopolysaccharide-induced rat fulminant hepatic failure model.

The following Mgst2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mgst2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01228	NM_001106430.1 Latest version!	Rattus norvegicus microsomal glutathione S-transferase 2 (Mgst2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mgst2 ( NM_001106430.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099900.1 Rattus norvegicus microsomal glutathione S-transferase 2 (Mgst2), mRNA.

Price & Availability↑

CloneID	ORa01228
Clone ID Related Accession (Same CDS sequence)	NM_001106430.1
Accession Version	NM_001106430.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	microsomal glutathione S-transferase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474003.2. On or before Oct 4, 2007 this sequence version replaced XM_215562.3, XM_001054384.1, XM_001054438.1. ##Evidence-Data-START## Transcript exon combination :: BG664314.1, FM106588.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689594, SAMEA2689597 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGGGG ATTCAAGCCT GCTGGCTGCA GTCTCCCTTC TCTCTGCCTG TCAGCAAAGT 
TATTTTGCTT TGCAAGTCGG ACGAGTAAGA TTAAAATACA AGATCGCACC TCCAGCAGTC 
ACGGGCTCTC TGGAGTTTGA GAGAATATTT CGCGCACAGC AAAACTCTTT GGAGTTTTAT 
TCCGTATTCA TCATATCGCT GTGGATGGCT GGATGGTATT TCAATCAAGT TTTTGCAACC 
TGTCTGGGTC TCCTGTACAT ATACGCCCGT CACAAGTATT TCTGGGGCTA TGCAGAAGCC 
GCTGAAAAAA GGATCATTGG TTTCCGGCTG AGCCTGGGCA TTTTGGCCTT GCTGACTGTC 
CTCGCTGTCC TGGGGGTAGC AAGCAGATTC CTGGACGAAT ACCTGGACTT TCATGTTGCC 
AAGAAACTGA AGCGGCCCTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099900.1
CDS	167..610
Translation	MAGDSSLLAAVSLLSACQQSYFALQVGRVRLKYKIAPPAVTGSLEFERIFRAQQNSLEFYSVFIISLWMAGWYFNQVFATCLGLLYIYARHKYFWGYAEAAEKRIIGFRLSLGILALLTVLAVLGVASRFLDEYLDFHVAKKLKRPF

Target ORF information:

RefSeq Version	NM_001106430.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus microsomal glutathione S-transferase 2 (Mgst2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106430.1

ORF Insert Sequence:

ATGGCGGGGG ATTCAAGCCT GCTGGCTGCA GTCTCCCTTC TCTCTGCCTG TCAGCAAAGT 
TATTTTGCTT TGCAAGTCGG ACGAGTAAGA TTAAAATACA AGATCGCACC TCCAGCAGTC 
ACGGGCTCTC TGGAGTTTGA GAGAATATTT CGCGCACAGC AAAACTCTTT GGAGTTTTAT 
TCCGTATTCA TCATATCGCT GTGGATGGCT GGATGGTATT TCAATCAAGT TTTTGCAACC 
TGTCTGGGTC TCCTGTACAT ATACGCCCGT CACAAGTATT TCTGGGGCTA TGCAGAAGCC 
GCTGAAAAAA GGATCATTGG TTTCCGGCTG AGCCTGGGCA TTTTGGCCTT GCTGACTGTC 
CTCGCTGTCC TGGGGGTAGC AAGCAGATTC CTGGACGAAT ACCTGGACTT TCATGTTGCC 
AAGAAACTGA AGCGGCCCTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Catalytic characterization of human microsomal glutathione S-transferase 2: identification of rate-limiting steps.
Biochemistry52(10)1755-64(2013 Mar)
Ahmad S,Niegowski D,Wetterholm A,Haeggstr?m JZ,Morgenstern R,Rinaldo-Matthis A

Enhanced expressions and activations of leukotriene C4 synthesis enzymes in D-galactosamine/lipopolysaccharide-induced rat fulminant hepatic failure model.
World journal of gastroenterology14(17)2748-56(2008 May)
Ma KF,Yang HY,Chen Z,Qi LY,Zhu DY,Lou YJ

Sodium nitroprusside regulates mRNA expressions of LTC4 synthesis enzymes in hepatic ischemia/reperfusion injury rats via NF-kappaB signaling pathway.
Pharmacology80(1)11-20(2007)
Yang SL,Chen LJ,Kong Y,Xu D,Lou YJ

Molecular and catalytic properties of three rat leukotriene C(4) synthase homologs.
Biochemical and biophysical research communications312(2)271-6(2003 Dec)
Schr?der O,Sj?str?m M,Qiu H,Stein J,Jakobsson PJ,Haeggstr?m JZ

The role of glutathione-S-transferase in anti-cancer drug resistance.
Oncogene22(47)7369-75(2003 Oct)
Townsend DM,Tew KD