Hist1h4m cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hist1h4m
Entrez Gene ID	291152
Full Name	histone cluster 1, H4m
Synonyms	Hist1h4b,Hist4h4
General protein information	Preferred Names histone cluster 1, H4m Names histone H4 histone 1, H4m
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001271221.1	NP_001258150.1	histone H4

Pathways from BioSystems

Homologies

	LOC696253	XP_001085940.1
Gallus gallus (chicken)	HIST1H46L5	XP_001233095.1
Mus musculus (house mouse)	Hist1h4d	NP_783585.1
Rattus norvegicus (Norway rat)	Hist1h4m	NP_001258150.1
Homo sapiens (human)	HIST1H4A	NP_003529.1
Bos taurus (cattle)	LOC516742	XP_002686104.1
Oryza sativa (rice)	Os07g0549900	NP_001175250.1
Danio rerio (zebrafish)	LOC100005308	XP_001339600.2
Caenorhabditis elegans (roundworm)	his-67	NP_492641.1
Pan troglodytes (chimpanzee)	LOC748532	XP_003311105.1
Drosophila melanogaster (fruit fly)	His4:CG33887	NP_001027337.1
Xenopus tropicalis (tropical clawed frog)	LOC100495257	XP_002933937.1

Gene Ontology
Bibliography

Related articles in PubMed

Detection of histone acetylation levels in the dorsal hippocampus reveals early tagging on specific residues of H2B and H4 histones in response to learning.
Bousiges O, Neidl R, Majchrzak M, Muller MA, Barbelivien A, Pereira de Vasconcelos A, Schneider A, Loeffler JP, Cassel JC, Boutillier AL
PloS one8(3)e57816(2013)

Correlation between the expression of the histone H4 mRNA variant H4-v.1 and the levels of histone H4-(86-100) and H4-(89-102) (OGP) in various rat tissues and alveolar macrophages.
Poirier R, Lemaire I, Dumont M, Leduc N, Le HT, Lemaire S
Peptides26(8)1503-11(2005 Aug)

Biosynthesis of osteogenic growth peptide via alternative translational initiation at AUG85 of histone H4 mRNA.
Bab I, Smith E, Gavish H, Attar-Namdar M, Chorev M, Chen YC, Muhlrad A, Birnbaum MJ, Stein G, Frenkel B
The Journal of biological chemistry274(20)14474-81(1999 May)

Evidence indicating proximity in the nucleosome between the histone H4 N termini and the globular domain of histone H1.
Ban?res JL, Essalouh L, Jariel-Encontre I, Mesnier D, Garrod S, Parello J
Journal of molecular biology243(1)48-59(1994 Oct)

[Primary structure of glycine-rich and arginine-rich histone isolated from chloroleukemic tumor of the rat].
Sautiere P, Tyrou D, Moschetto Y, Biserte G
Biochimie53(4)479-83(1971)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

H3, H4 and H2B underwent differential acetylation at specific sites depending on whether rats had been exposed to the context of a task without having to learn or had to learn about a place or fear.
Title: Detection of histone acetylation levels in the dorsal hippocampus reveals early tagging on specific residues of H2B and H4 histones in response to learning.

The following Hist1h4m gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hist1h4m cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00020	NM_001271221.1 Latest version!	Rattus norvegicus histone cluster 1, H4m (Hist1h4m), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hist1h4m ( NM_001271221.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001258150.1 Rattus norvegicus histone cluster 1, H4m (Hist1h4m), mRNA.

Price & Availability↑

CloneID	ORa00020
Clone ID Related Accession (Same CDS sequence)	NM_001271221.1
Accession Version	NM_001271221.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Rattus norvegicus(Norway rat)
Product	histone H4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAHX01091907.1. On Sep 9, 2012 this sequence version replaced XM_003752998.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence. The genomic coordinates used for the transcript record were based on alignments.

ATGTCTGGCC GAGGTAAGGG CGGGAAGGGT CTGGGCAAAG GCGGCGCTAA GCGCCACCGC 
AAAGTCCTGC GCGACAACAT CCAGGGCATC ACTAAGCCCG CCATCCGCCG CTTGGCTCGG 
CGGGGAGGAG TGAAGCGCAT CTCCGGCCTC ATCTACGAGG AGACCCGCGG TGTGCTGAAG 
GTGTTCCTGG AGAACGTGAT CCGCGACGCC GTCACCTACA CAGAGCACGC CAAGCGCAAG 
ACTGTCACTG CCATGGATGT TGTCTATGCG CTTAAGCGCC AGGGCCGCAC TCTCTACGGC 
TTCGGTGGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258150.1
CDS	1..312
Translation	MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG

Target ORF information:

RefSeq Version	NM_001271221.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus histone cluster 1, H4m (Hist1h4m), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271221.1

ORF Insert Sequence:

ATGTCTGGCC GAGGTAAGGG CGGGAAGGGT CTGGGCAAAG GCGGCGCTAA GCGCCACCGC 
AAAGTCCTGC GCGACAACAT CCAGGGCATC ACTAAGCCCG CCATCCGCCG CTTGGCTCGG 
CGGGGAGGAG TGAAGCGCAT CTCCGGCCTC ATCTACGAGG AGACCCGCGG TGTGCTGAAG 
GTGTTCCTGG AGAACGTGAT CCGCGACGCC GTCACCTACA CAGAGCACGC CAAGCGCAAG 
ACTGTCACTG CCATGGATGT TGTCTATGCG CTTAAGCGCC AGGGCCGCAC TCTCTACGGC 
TTCGGTGGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Detection of histone acetylation levels in the dorsal hippocampus reveals early tagging on specific residues of H2B and H4 histones in response to learning.
PloS one8(3)e57816(2013)
Bousiges O,Neidl R,Majchrzak M,Muller MA,Barbelivien A,Pereira de Vasconcelos A,Schneider A,Loeffler JP,Cassel JC,Boutillier AL

Correlation between the expression of the histone H4 mRNA variant H4-v.1 and the levels of histone H4-(86-100) and H4-(89-102) (OGP) in various rat tissues and alveolar macrophages.
Peptides26(8)1503-11(2005 Aug)
Poirier R,Lemaire I,Dumont M,Leduc N,Le HT,Lemaire S

Biosynthesis of osteogenic growth peptide via alternative translational initiation at AUG85 of histone H4 mRNA.
The Journal of biological chemistry274(20)14474-81(1999 May)
Bab I,Smith E,Gavish H,Attar-Namdar M,Chorev M,Chen YC,Muhlrad A,Birnbaum MJ,Stein G,Frenkel B

Evidence indicating proximity in the nucleosome between the histone H4 N termini and the globular domain of histone H1.
Journal of molecular biology243(1)48-59(1994 Oct)
Ban?res JL,Essalouh L,Jariel-Encontre I,Mesnier D,Garrod S,Parello J

[Primary structure of glycine-rich and arginine-rich histone isolated from chloroleukemic tumor of the rat].
Biochimie53(4)479-83(1971)
Sautiere P,Tyrou D,Moschetto Y,Biserte G