Cntn6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cntn6
Entrez Gene ID	27256
Full Name	contactin 6
Synonyms	NB-3
General protein information	Preferred Names contactin 6 Names contactin-6 neural adhesion molecule neural recognition molecule NB-3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q41
Summary	glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule; may play a role in axonogenesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013225.1	NP_037357.1	contactin-6 precursor
XM_017592492.1	XP_017447981.1	contactin-6 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CNTN6	XP_516244.2
Rattus norvegicus (Norway rat)	Cntn6	NP_037357.1
Canis lupus familiaris (dog)	CNTN6	XP_005632304.1
Mus musculus (house mouse)	Cntn6	NP_059079.2
Homo sapiens (human)	CNTN6	NP_055276.1
	CNTN6	XP_001101681.1
Bos taurus (cattle)	CNTN6	NP_001178388.1
Gallus gallus (chicken)	CNTN6	XP_004944758.1

Gene Ontology
Bibliography

Related articles in PubMed

Adropin is a brain membrane-bound protein regulating physical activity via the NB-3/Notch signaling pathway in mice.
Wong CM, Wang Y, Lee JT, Huang Z, Wu D, Xu A, Lam KS
The Journal of biological chemistry289(37)25976-86(2014 Sep)

Contribution of the neural cell recognition molecule NB-3 to synapse formation between parallel fibers and Purkinje cells in mouse.
Sakurai K, Toyoshima M, Ueda H, Matsubara K, Takeda Y, Karagogeos D, Shimoda Y, Watanabe K
Developmental neurobiology69(12)811-24(2009 Oct)

NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes.
Cui XY, Hu QD, Tekaya M, Shimoda Y, Ang BT, Nie DY, Sun L, Hu WP, Karsak M, Duka T, Takeda Y, Ou LY, Dawe GS, Yu FG, Ahmed S, Jin LH, Schachner M, Watanabe K, Arsenijevic Y, Xiao ZC
The Journal of biological chemistry279(24)25858-65(2004 Jun)

Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup.
Takeda Y, Akasaka K, Lee S, Kobayashi S, Kawano H, Murayama S, Takahashi N, Hashimoto K, Kano M, Asano M, Sudo K, Iwakura Y, Watanabe K
Journal of neurobiology56(3)252-65(2003 Sep)

Novel neural adhesion molecules in the Contactin/F3 subgroup of the immunoglobulin superfamily: isolation and characterization of cDNAs from rat brain.
Ogawa J, Kaneko H, Masuda T, Nagata S, Hosoya H, Watanabe K
Neuroscience letters218(3)173-6(1996 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NB-3/Notch1 pathway promotes neural progenitor cell differentiation into oligodendrocytes via Deltex1.
Title: NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes.

Immunohistochemistry of the cerebellum from 3-month-old rats demonstrates that lobules 1-8 are distinct from lobules 9 and 10 with respect to localization of NB-3 protein.
Title: Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup.

The following Cntn6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cntn6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa60777	XM_017592492.1 Latest version!	Rattus norvegicus contactin 6 (Cntn6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
ORa42507	NM_013225.1 Latest version!	Rattus norvegicus contactin 6 (Cntn6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$755.30 $1079.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cntn6 ( XM_017592492.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447981.1 Rattus norvegicus contactin 6 (Cntn6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa60777
Clone ID Related Accession (Same CDS sequence)	XM_017592492.1
Accession Version	XM_017592492.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3012bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	contactin-6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGTTGC TATGGAAACT GGTAATTCTG CTGCCACTCA TAAACTCTTG TGCAGGTGAG 
AGTCGTTTTA CTCGTCCTAT TTTTATCCAG GAGCCACAGG ATGTCATTTT TCCGTTGGAT 
TTATCTAGAT CTGAAATTAT TCTGAGTTGT ACTGCAAGTG GATACCCTTC TCCCCACTAC 
AGGTGGAAAC AGAATGGTAC AGACATTGAC TTCAGCATGA CTTATCACTA TAGGTTGGAT 
GGAGGCAGTT TGGCCATCAG CAGCCCCAGA ACAGATCAAG ATATTGGCAT ATACCAGTGT 
CTGGCCACCA ATCCGGTGGG CACCATTCTG AGTAGAAAAG CCAAACTACA GTTTGCATAT 
ATTGAAGACT TTGAAACCAA ATCCAGAAGC ACGGTCTCTG TCCGGGAAGG TCAAGGAGTG 
GTACTCCTCT GTGGCCCACC ACCACATTTT GGAGAATTAT CATATGATTG GACCTTCAAT 
GATAACCCTT TGTATGTTCA AGAGGACAAG CGACGATTTG TATCTCAAAA CACAGGGAAC 
TTGTACATTG CCAAAGTAGA ACCGTCTGAT GTGGGCAATT ATACTTGCTT TGTCACAAAC 
AAAGAGGCCC ACAGAAGTGT CCAAGGACCA CCTACTCCTT TAGTGCAGCG CACTGATGGT 
GTCATGGGGG AATATGAGCC AAAGATTGAA GTGCGTTTTC CTGAAACAAT ACAAGCTGCA 
AAGGATTCAT CTGTAAAACT GGAATGCTTT GCCCTTGGAA ATCCAGTCCC TGATATTAGT 
TGGAGGCGGT TGGATGGAAG CCCGATGCCA GGGAAAGTCA AGTACAGCAA CTCCCAAGCT 
ACCCTTGAAA TCCCCAAGTT TCAACAAGAG GATGAAGGCT TCTATGAGTG CGTTGCAGGT 
AACCTTCGAG GAAGAAACCT TGCAAAGGGT CAACTCATTT TCTATGCTCC TCCAGAATGG 
GAACAGAAAA TCCAAAATAC ATACCTTTCT ATCTATGACA GCTTGTTTTG GGAATGCAAA 
GCTAGTGGAA ACCCAAATCC TTCGTACACG TGGCTAAAGA ATGGTGAACG TCTCAACACA 
GAAGAGAGAA TTCAGACTGA AAATGGGACT CTTATCATCA CCATGCTGAA CGTGTCAGAC 
TCTGGGATCT ACCAGTGTGC TGCAGAAAAC AAGTATCAGA CAATTTATGC AAATGCAGAA 
TTGAGAGTTT TAGCCTCAGC TCCAGATTTC TCAAAAAATC CCATTAAAAA AATTTCAGTT 
GTTCAAGTTG GTGGTGACAT TTCAATCGAA TGCAAACCAA ACGCTTTCCC CAAACCTGTG 
TACTCTTGGG ATGGTGGGAG AGATTACAAA AAAATAAATG AACCTGTTTT TTTCTTGGAG 
GATGGTAGCC TTAAGATATG CAATGTTACC AGATCAGATG CTGGATCTTA TACTTGCGTA 
GCCACAAATC AATTTGGCAA TGGGAAAAGC AGTGGTAGTC TCATCGTAAA AGAGCGAACG 
GTCATTACAG TACCACCGTC TAAAATGGAT GTTACAGTTG GAGAGAGCAT TGTCTTACCC 
TGCCAGGTGT CTCATGATCC CACCATGGAA GTTCTCTTTG TTTGGTACTT CAATGGAGAT 
GTCATAGATT TAAAGAAAGG AGTGGCTCAT TTTGAACGAA TTGGGGGTGA ATCTGTTGGG 
GATTTGATGA TAAGGAATAT TCAATTAGGC CATTCGGGAA AATATCTATG CACAGTACAA 
ACAACACTAG AACGCTTGTC TGCTGTCGCT GATATCATTG TGAGAGGTCC TCCTGGTCCC 
CCAGAAGATG TAAAAGTGGA GCACATCTCT AGTACCACGT CCCAGCTCAG CTGGAGACCT 
GGTCCTGATA ATAACAGCCC CATTCAAATT TTTACCATTC AGACTCGGAC ACCCTTCTCT 
GTGGGCTGGC AAGCTGTTGC CACAGTCCCT GAAATTCTCA ATGGACAGAC ATACAATGCA 
ACAGTCATTG GTTTGAGTCC TTGGGTGGAA TATGAATTTC GTGTTGTTGC TGGGAACAAC 
ATTGGAATTG GAGAGCCAAG CAAACCATCA GAGTTGCTGA GAACCAAAGC ATCAATCCCC 
AATGTGGCAC CAGTAAATAT CAATGGAGGT GGTGGGAGCA GATCGGAACT TGTCATTACG 
TGGGAGCCTA TTCCAGAAGA ACTACAGAAT GGAGAGGGGT TTGGATATAT CATCATGTTC 
CGGCCAGTGG GCTCAACAAC CTGGATGAAA GAAAAGGTGG CTCTTGTAGA ATCTTCAAAG 
TTCATCTACA GAAATGAAAG CATCATGCCT TTGTCTCCCT TTGAAGTCAA AGTGGGAGTG 
TACAACAATG AAGGCGAAGG TTCCCTGAGT ACCGTGTCTA TTGTCTACTC TGGGGAAGAT 
GAACCTCGGC TGGCTCCAAG AGGAACTTCT GTCCAGAGTT TTTCTGCTTC TGACATGGAG 
GTTTCCTGGA ATGCCATTGC TTGGAATAGA AACACTGGAA GAGTGCTGGG CTATGAGGTC 
TTATACTGGA CTGACAACTC CAAAGAATCT ATGATTGGGA AAATTAGAGT CAGTGGAAAT 
GTCACAACCA AGAATATTAC AGGGCTAAGA GCTAATACGA TTTACTTTGC TTCTGTGAGA 
GCCTACAACA CTGCAGGGAC AGGACCCTCA AGTCCACCAG TTAATGTCAC CACGAAAAAG 
TCCCCACCTA GCCAACCACC AGCAAACATT GCCTGGAAGC TGTCAAATTC CAAATTATGC 
CTGAACTGGG AGCATGTAAA AACTATGGAA AATGAGTCTG AAGTGCTGGG CTACAAGATC 
CTCTATCGGC AGAACCGACA GAGTAAAACT CATGTCTTGG AAACAAATAA TACATCAGCT 
GAGCTACTGG TTCCATTTGA AGAAGACTAT TTGATCGAAA TCAGAACAGT CAGTGATGGT 
GGAGACGGAA GCAGTAGTGA GGAAATCAGA ATTCCAAAAA TGTCAAGTGA GTTCAGTTGC 
TGCTTTGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447981.1
CDS	82..3093
Translation	MRLLWKLVILLPLINSCAGESRFTRPIFIQEPQDVIFPLDLSRSEIILSCTASGYPSPHYRWKQNGTDIDFSMTYHYRLDGGSLAISSPRTDQDIGIYQCLATNPVGTILSRKAKLQFAYIEDFETKSRSTVSVREGQGVVLLCGPPPHFGELSYDWTFNDNPLYVQEDKRRFVSQNTGNLYIAKVEPSDVGNYTCFVTNKEAHRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPMPGKVKYSNSQATLEIPKFQQEDEGFYECVAGNLRGRNLAKGQLIFYAPPEWEQKIQNTYLSIYDSLFWECKASGNPNPSYTWLKNGERLNTEERIQTENGTLIITMLNVSDSGIYQCAAENKYQTIYANAELRVLASAPDFSKNPIKKISVVQVGGDISIECKPNAFPKPVYSWDGGRDYKKINEPVFFLEDGSLKICNVTRSDAGSYTCVATNQFGNGKSSGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPTMEVLFVWYFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLGHSGKYLCTVQTTLERLSAVADIIVRGPPGPPEDVKVEHISSTTSQLSWRPGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGQTYNATVIGLSPWVEYEFRVVAGNNIGIGEPSKPSELLRTKASIPNVAPVNINGGGGSRSELVITWEPIPEELQNGEGFGYIIMFRPVGSTTWMKEKVALVESSKFIYRNESIMPLSPFEVKVGVYNNEGEGSLSTVSIVYSGEDEPRLAPRGTSVQSFSASDMEVSWNAIAWNRNTGRVLGYEVLYWTDNSKESMIGKIRVSGNVTTKNITGLRANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLSNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHVLETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSEFSCCFV

Target ORF information:

RefSeq Version	XM_017592492.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus contactin 6 (Cntn6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592492.1

ORF Insert Sequence:

ATGAGGTTGC TATGGAAACT GGTAATTCTG CTGCCACTCA TAAACTCTTG TGCAGGTGAG 
AGTCGTTTTA CTCGTCCTAT TTTTATCCAG GAGCCACAGG ATGTCATTTT TCCGTTGGAT 
TTATCTAGAT CTGAAATTAT TCTGAGTTGT ACTGCAAGTG GATACCCTTC TCCCCACTAC 
AGGTGGAAAC AGAATGGTAC AGACATTGAC TTCAGCATGA CTTATCACTA TAGGTTGGAT 
GGAGGCAGTT TGGCCATCAG CAGCCCCAGA ACAGATCAAG ATATTGGCAT ATACCAGTGT 
CTGGCCACCA ATCCGGTGGG CACCATTCTG AGTAGAAAAG CCAAACTACA GTTTGCATAT 
ATTGAAGACT TTGAAACCAA ATCCAGAAGC ACGGTCTCTG TCCGGGAAGG TCAAGGAGTG 
GTACTCCTCT GTGGCCCACC ACCACATTTT GGAGAATTAT CATATGATTG GACCTTCAAT 
GATAACCCTT TGTATGTTCA AGAGGACAAG CGACGATTTG TATCTCAAAA CACAGGGAAC 
TTGTACATTG CCAAAGTAGA ACCGTCTGAT GTGGGCAATT ATACTTGCTT TGTCACAAAC 
AAAGAGGCCC ACAGAAGTGT CCAAGGACCA CCTACTCCTT TAGTGCAGCG CACTGATGGT 
GTCATGGGGG AATATGAGCC AAAGATTGAA GTGCGTTTTC CTGAAACAAT ACAAGCTGCA 
AAGGATTCAT CTGTAAAACT GGAATGCTTT GCCCTTGGAA ATCCAGTCCC TGATATTAGT 
TGGAGGCGGT TGGATGGAAG CCCGATGCCA GGGAAAGTCA AGTACAGCAA CTCCCAAGCT 
ACCCTTGAAA TCCCCAAGTT TCAACAAGAG GATGAAGGCT TCTATGAGTG CGTTGCAGGT 
AACCTTCGAG GAAGAAACCT TGCAAAGGGT CAACTCATTT TCTATGCTCC TCCAGAATGG 
GAACAGAAAA TCCAAAATAC ATACCTTTCT ATCTATGACA GCTTGTTTTG GGAATGCAAA 
GCTAGTGGAA ACCCAAATCC TTCGTACACG TGGCTAAAGA ATGGTGAACG TCTCAACACA 
GAAGAGAGAA TTCAGACTGA AAATGGGACT CTTATCATCA CCATGCTGAA CGTGTCAGAC 
TCTGGGATCT ACCAGTGTGC TGCAGAAAAC AAGTATCAGA CAATTTATGC AAATGCAGAA 
TTGAGAGTTT TAGCCTCAGC TCCAGATTTC TCAAAAAATC CCATTAAAAA AATTTCAGTT 
GTTCAAGTTG GTGGTGACAT TTCAATCGAA TGCAAACCAA ACGCTTTCCC CAAACCTGTG 
TACTCTTGGG ATGGTGGGAG AGATTACAAA AAAATAAATG AACCTGTTTT TTTCTTGGAG 
GATGGTAGCC TTAAGATATG CAATGTTACC AGATCAGATG CTGGATCTTA TACTTGCGTA 
GCCACAAATC AATTTGGCAA TGGGAAAAGC AGTGGTAGTC TCATCGTAAA AGAGCGAACG 
GTCATTACAG TACCACCGTC TAAAATGGAT GTTACAGTTG GAGAGAGCAT TGTCTTACCC 
TGCCAGGTGT CTCATGATCC CACCATGGAA GTTCTCTTTG TTTGGTACTT CAATGGAGAT 
GTCATAGATT TAAAGAAAGG AGTGGCTCAT TTTGAACGAA TTGGGGGTGA ATCTGTTGGG 
GATTTGATGA TAAGGAATAT TCAATTAGGC CATTCGGGAA AATATCTATG CACAGTACAA 
ACAACACTAG AACGCTTGTC TGCTGTCGCT GATATCATTG TGAGAGGTCC TCCTGGTCCC 
CCAGAAGATG TAAAAGTGGA GCACATCTCT AGTACCACGT CCCAGCTCAG CTGGAGACCT 
GGTCCTGATA ATAACAGCCC CATTCAAATT TTTACCATTC AGACTCGGAC ACCCTTCTCT 
GTGGGCTGGC AAGCTGTTGC CACAGTCCCT GAAATTCTCA ATGGACAGAC ATACAATGCA 
ACAGTCATTG GTTTGAGTCC TTGGGTGGAA TATGAATTTC GTGTTGTTGC TGGGAACAAC 
ATTGGAATTG GAGAGCCAAG CAAACCATCA GAGTTGCTGA GAACCAAAGC ATCAATCCCC 
AATGTGGCAC CAGTAAATAT CAATGGAGGT GGTGGGAGCA GATCGGAACT TGTCATTACG 
TGGGAGCCTA TTCCAGAAGA ACTACAGAAT GGAGAGGGGT TTGGATATAT CATCATGTTC 
CGGCCAGTGG GCTCAACAAC CTGGATGAAA GAAAAGGTGG CTCTTGTAGA ATCTTCAAAG 
TTCATCTACA GAAATGAAAG CATCATGCCT TTGTCTCCCT TTGAAGTCAA AGTGGGAGTG 
TACAACAATG AAGGCGAAGG TTCCCTGAGT ACCGTGTCTA TTGTCTACTC TGGGGAAGAT 
GAACCTCGGC TGGCTCCAAG AGGAACTTCT GTCCAGAGTT TTTCTGCTTC TGACATGGAG 
GTTTCCTGGA ATGCCATTGC TTGGAATAGA AACACTGGAA GAGTGCTGGG CTATGAGGTC 
TTATACTGGA CTGACAACTC CAAAGAATCT ATGATTGGGA AAATTAGAGT CAGTGGAAAT 
GTCACAACCA AGAATATTAC AGGGCTAAGA GCTAATACGA TTTACTTTGC TTCTGTGAGA 
GCCTACAACA CTGCAGGGAC AGGACCCTCA AGTCCACCAG TTAATGTCAC CACGAAAAAG 
TCCCCACCTA GCCAACCACC AGCAAACATT GCCTGGAAGC TGTCAAATTC CAAATTATGC 
CTGAACTGGG AGCATGTAAA AACTATGGAA AATGAGTCTG AAGTGCTGGG CTACAAGATC 
CTCTATCGGC AGAACCGACA GAGTAAAACT CATGTCTTGG AAACAAATAA TACATCAGCT 
GAGCTACTGG TTCCATTTGA AGAAGACTAT TTGATCGAAA TCAGAACAGT CAGTGATGGT 
GGAGACGGAA GCAGTAGTGA GGAAATCAGA ATTCCAAAAA TGTCAAGTGA GTTCAGTTGC 
TGCTTTGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cntn6 ( NM_013225.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037357.1 Rattus norvegicus contactin 6 (Cntn6), mRNA.

Price & Availability↑

CloneID	ORa42507
Clone ID Related Accession (Same CDS sequence)	NM_013225.1
Accession Version	NM_013225.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3087bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	contactin-6 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D87248.1. On Dec 17, 2003 this sequence version replaced XM_346713.1. ##Evidence-Data-START## Transcript exon combination :: D87248.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGGTTGC TATGGAAACT GGTAATTCTG CTGCCACTCA TAAACTCTTG TGCAGGTGAG 
AGTCGTTTTA CTCGTCCTAT TTTTATCCAG GAGCCACAGG ATGTCATTTT TCCGTTGGAT 
TTATCTAGAT CTGAAATTAT TCTGAGTTGT ACTGCAAGTG GATACCCTTC TCCCCACTAC 
AGGTGGAAAC AGAATGGTAC AGACATTGAC TTCAGCATGA CTTATCACTA TAGGTTGGAT 
GGAGGCAGTT TGGCCATCAG CAGCCCCAGA ACAGATCAAG ATATTGGCAT ATACCAGTGT 
CTGGCCACCA ATCCGGTGGG CACCATTCTG AGTAGAAAAG CCAAACTACA GTTTGCATAT 
ATTGAAGACT TTGAAACCAA ATCCAGAAGC ACGGTCTCTG TCCGGGAAGG TCAAGGAGTG 
GTACTCCTCT GTGGCCCACC ACCACATTTT GGAGAATTAT CATATGATTG GACCTTCAAT 
GATAACCCTT TGTATGTTCA AGAGGACAAG CGACGATTTG TATCTCAAAA CACAGGGAAC 
TTGTACATTG CCAAAGTAGA ACCGTCTGAT GTGGGCAATT ATACTTGCTT TGTCACAAAC 
AAAGAGGCCC ACAGAAGTGT CCAAGGACCA CCTACTCCTT TAGTGCAGCG CACTGATGGT 
GTCATGGGGG AATATGAGCC AAAGATTGAA GTGCGTTTTC CTGAAACAAT ACAAGCTGCA 
AAGGATTCAT CTGTAAAACT GGAATGCTTT GCCCTTGGAA ATCCAGTCCC TGATATTAGT 
TGGAGGCGGT TGGATGGAAG CCCGATGCCA GGGAAAGTCA AGTACAGCAA CTCCCAAGCT 
ACCCTTGAAA TCCCCAAGTT TCAACAAGAG GATGAAGGCT TCTATGAGTG CGTTGCAGGT 
AACCTTCGAG GAAGAAACCT TGCAAAGGGT CAACTCATTT TCTATGCTCC TCCAGAATGG 
GAACAGAAAA TCCAAAATAC ATACCTTTCT ATCTATGACA GCTTGTTTTG GGAATGCAAA 
GCTAGTGGAA ACCCAAATCC TTCGTACACG TGGCTAAAGA ATGGTGAACG TCTCAACACA 
GAAGAGAGAA TTCAGACTGA AAATGGGACT CTTATCATCA CCATGCTGAA CGTGTCAGAC 
TCTGGGATCT ACCAGTGTGC TGCAGAAAAC AAATATCAGA CAATTTATGC AAATGCAGAA 
TTGAGAGTTT TAGCCTCAGC TCCAGATTTC TCAAAAAATC CCATTAAAAA AATTTCAGTT 
GTTCAAGTTG GTGGTGACAT TTCAATCGAA TGCAAACCAA ACGCTTTCCC CAAAGCATCT 
ATTTCCTGGA AAAGAGGAAC GGAGAACCTG AAGCAAAGTA AAAGAGTTTT TTTCTTGGAG 
GATGGTAGCC TTAAGATATG CAATGTTACC AGATCAGATG CTGGATCTTA TACTTGCGTA 
GCCACAAATC AATTTGGCAA TGGGAAAAGC AGTGGTAGTC TCATCGTAAA AGAGCGAACG 
GTCATTACAG TACCACCGTC TAAAATGGAT GTTACAGTTG GAGAGAGCAT TGTCTTACCC 
TGCCAGGTGT CTCATGATCC CACCATGGAA GTTCTCTTTG TTTGGTACTT CAATGGAGAT 
GTCATAGATT TAAAGAAAGG AGTGGCTCAT TTTGAACGAA TTGGGGGTGA ATCTGTTGGG 
GATTTGATGA TAAGGAATAT TCAATTAGGC CATTCGGGAA AATATCTATG CACAGTACAA 
ACAACACTAG AACGCTTGTC TGCTGTCGCT GATATCATTG TGAGAGGTCC TCCTGGTCCC 
CCAGAAGATG TAAAAGTGGA GCACATCTCT AGTACCACGT CCCAGCTCAG CTGGAGACCT 
GGTCCTGATA ATAACAGCCC CATTCAAATT TTTACCATTC AGACTCGGAC ACCCTTCTCT 
GTGGGCTGGC AAGCTGTTGC CACAGTCCCT GAAATTCTCA ATGGACAGAC ATACAATGCA 
ACAGTCATTG GTTTGAGTCC TTGGGTGGAA TATGAATTTC GTGTTGTTGC TGGGAACAAC 
ATTGGAATTG GAGAGCCAAG CAAACCATCA GAGTTGCTGA GAACCAAAGC ATCAATCCCC 
AATGTGGCAC CAGTAAATAT CAATGGAGGT GGTGGGAGCA GATCGGAACT TGTCATTACG 
TGGGAGCCTA TTCCAGAAGA ACTACAGAAT GGAGAGGGGT TTGGATATAT CATCATGTTC 
CGGCCAGTGG GCTCAACAAC CTGGATGAAA GAAAAGGTGG CTCTTGTAGA ATCTTCAAAG 
TTCATCTACA GAAATGAAAG CATCATGCCT TTGTCTCCCT TTGAAGTCAA AGTGGGAGTG 
TACAACAATG AAGGCGAAGG TTCCCTGAGT ACCGTGTCTA TTGTCTACTC TGGGGAAGAT 
GAACCTCGGC TGGCTCCAAG AGGAACTTCT GTCCAGAGTT TTTCTGCTTC TGACATGGAG 
GTTTCCTGGA ATGCCATTGC TTGGAATAGA AACACTGGAA GAGTGCTGGG CTATGAGGTC 
TTATACTGGA CTGACAACTC CAAAGAATCT ATGATTGGGA AAATTAGAGT CAGTGGAAAT 
GTCACAACCA AGAATATTAC AGGGCTAAGA GCTAATACGA TTTACTTTGC TTCTGTGAGA 
GCCTACAACA CTGCAGGGAC AGGACCCTCA AGTCCACCAG TTAATGTCAC CACGAAAAAG 
TCCCCACCTA GCCAACCACC AGCAAACATT GCCTGGAAGC TGTCAAATTC CAAATTATGC 
CTGAACTGGG AGCATGTAAA AACTATGGAA AATGAGTCTG AAGTGCTGGG CTACAAGATC 
CTCTATCGGC AGAACCGACA GAGTAAAACT CATGTCTTGG AAACAAATAA TACATCAGCT 
GAGCTACTGG TTCCATTTGA AGAAGACTAT TTGATCGAAA TCAGAACAGT CAGTGATGGT 
GGAGACGGAA GCAGTAGTGA GGAAATCAGA ATTCCAAAAA TGTCAAGTTT GAGTTCCGTG 
GGAGTTCAGA TCTTGAAGCC CAGTACCCAG TTCCTGACAA TGGTTGGATT TTTTTACTGT 
TTTGTTATTC AGCCACTTTC ACGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037357.1
CDS	188..3274
Translation	MRLLWKLVILLPLINSCAGESRFTRPIFIQEPQDVIFPLDLSRSEIILSCTASGYPSPHYRWKQNGTDIDFSMTYHYRLDGGSLAISSPRTDQDIGIYQCLATNPVGTILSRKAKLQFAYIEDFETKSRSTVSVREGQGVVLLCGPPPHFGELSYDWTFNDNPLYVQEDKRRFVSQNTGNLYIAKVEPSDVGNYTCFVTNKEAHRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPMPGKVKYSNSQATLEIPKFQQEDEGFYECVAGNLRGRNLAKGQLIFYAPPEWEQKIQNTYLSIYDSLFWECKASGNPNPSYTWLKNGERLNTEERIQTENGTLIITMLNVSDSGIYQCAAENKYQTIYANAELRVLASAPDFSKNPIKKISVVQVGGDISIECKPNAFPKASISWKRGTENLKQSKRVFFLEDGSLKICNVTRSDAGSYTCVATNQFGNGKSSGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPTMEVLFVWYFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLGHSGKYLCTVQTTLERLSAVADIIVRGPPGPPEDVKVEHISSTTSQLSWRPGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGQTYNATVIGLSPWVEYEFRVVAGNNIGIGEPSKPSELLRTKASIPNVAPVNINGGGGSRSELVITWEPIPEELQNGEGFGYIIMFRPVGSTTWMKEKVALVESSKFIYRNESIMPLSPFEVKVGVYNNEGEGSLSTVSIVYSGEDEPRLAPRGTSVQSFSASDMEVSWNAIAWNRNTGRVLGYEVLYWTDNSKESMIGKIRVSGNVTTKNITGLRANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLSNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHVLETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSVGVQILKPSTQFLTMVGFFYCFVIQPLSR

Target ORF information:

RefSeq Version	NM_013225.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus contactin 6 (Cntn6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013225.1

ORF Insert Sequence:

ATGAGGTTGC TATGGAAACT GGTAATTCTG CTGCCACTCA TAAACTCTTG TGCAGGTGAG 
AGTCGTTTTA CTCGTCCTAT TTTTATCCAG GAGCCACAGG ATGTCATTTT TCCGTTGGAT 
TTATCTAGAT CTGAAATTAT TCTGAGTTGT ACTGCAAGTG GATACCCTTC TCCCCACTAC 
AGGTGGAAAC AGAATGGTAC AGACATTGAC TTCAGCATGA CTTATCACTA TAGGTTGGAT 
GGAGGCAGTT TGGCCATCAG CAGCCCCAGA ACAGATCAAG ATATTGGCAT ATACCAGTGT 
CTGGCCACCA ATCCGGTGGG CACCATTCTG AGTAGAAAAG CCAAACTACA GTTTGCATAT 
ATTGAAGACT TTGAAACCAA ATCCAGAAGC ACGGTCTCTG TCCGGGAAGG TCAAGGAGTG 
GTACTCCTCT GTGGCCCACC ACCACATTTT GGAGAATTAT CATATGATTG GACCTTCAAT 
GATAACCCTT TGTATGTTCA AGAGGACAAG CGACGATTTG TATCTCAAAA CACAGGGAAC 
TTGTACATTG CCAAAGTAGA ACCGTCTGAT GTGGGCAATT ATACTTGCTT TGTCACAAAC 
AAAGAGGCCC ACAGAAGTGT CCAAGGACCA CCTACTCCTT TAGTGCAGCG CACTGATGGT 
GTCATGGGGG AATATGAGCC AAAGATTGAA GTGCGTTTTC CTGAAACAAT ACAAGCTGCA 
AAGGATTCAT CTGTAAAACT GGAATGCTTT GCCCTTGGAA ATCCAGTCCC TGATATTAGT 
TGGAGGCGGT TGGATGGAAG CCCGATGCCA GGGAAAGTCA AGTACAGCAA CTCCCAAGCT 
ACCCTTGAAA TCCCCAAGTT TCAACAAGAG GATGAAGGCT TCTATGAGTG CGTTGCAGGT 
AACCTTCGAG GAAGAAACCT TGCAAAGGGT CAACTCATTT TCTATGCTCC TCCAGAATGG 
GAACAGAAAA TCCAAAATAC ATACCTTTCT ATCTATGACA GCTTGTTTTG GGAATGCAAA 
GCTAGTGGAA ACCCAAATCC TTCGTACACG TGGCTAAAGA ATGGTGAACG TCTCAACACA 
GAAGAGAGAA TTCAGACTGA AAATGGGACT CTTATCATCA CCATGCTGAA CGTGTCAGAC 
TCTGGGATCT ACCAGTGTGC TGCAGAAAAC AAATATCAGA CAATTTATGC AAATGCAGAA 
TTGAGAGTTT TAGCCTCAGC TCCAGATTTC TCAAAAAATC CCATTAAAAA AATTTCAGTT 
GTTCAAGTTG GTGGTGACAT TTCAATCGAA TGCAAACCAA ACGCTTTCCC CAAAGCATCT 
ATTTCCTGGA AAAGAGGAAC GGAGAACCTG AAGCAAAGTA AAAGAGTTTT TTTCTTGGAG 
GATGGTAGCC TTAAGATATG CAATGTTACC AGATCAGATG CTGGATCTTA TACTTGCGTA 
GCCACAAATC AATTTGGCAA TGGGAAAAGC AGTGGTAGTC TCATCGTAAA AGAGCGAACG 
GTCATTACAG TACCACCGTC TAAAATGGAT GTTACAGTTG GAGAGAGCAT TGTCTTACCC 
TGCCAGGTGT CTCATGATCC CACCATGGAA GTTCTCTTTG TTTGGTACTT CAATGGAGAT 
GTCATAGATT TAAAGAAAGG AGTGGCTCAT TTTGAACGAA TTGGGGGTGA ATCTGTTGGG 
GATTTGATGA TAAGGAATAT TCAATTAGGC CATTCGGGAA AATATCTATG CACAGTACAA 
ACAACACTAG AACGCTTGTC TGCTGTCGCT GATATCATTG TGAGAGGTCC TCCTGGTCCC 
CCAGAAGATG TAAAAGTGGA GCACATCTCT AGTACCACGT CCCAGCTCAG CTGGAGACCT 
GGTCCTGATA ATAACAGCCC CATTCAAATT TTTACCATTC AGACTCGGAC ACCCTTCTCT 
GTGGGCTGGC AAGCTGTTGC CACAGTCCCT GAAATTCTCA ATGGACAGAC ATACAATGCA 
ACAGTCATTG GTTTGAGTCC TTGGGTGGAA TATGAATTTC GTGTTGTTGC TGGGAACAAC 
ATTGGAATTG GAGAGCCAAG CAAACCATCA GAGTTGCTGA GAACCAAAGC ATCAATCCCC 
AATGTGGCAC CAGTAAATAT CAATGGAGGT GGTGGGAGCA GATCGGAACT TGTCATTACG 
TGGGAGCCTA TTCCAGAAGA ACTACAGAAT GGAGAGGGGT TTGGATATAT CATCATGTTC 
CGGCCAGTGG GCTCAACAAC CTGGATGAAA GAAAAGGTGG CTCTTGTAGA ATCTTCAAAG 
TTCATCTACA GAAATGAAAG CATCATGCCT TTGTCTCCCT TTGAAGTCAA AGTGGGAGTG 
TACAACAATG AAGGCGAAGG TTCCCTGAGT ACCGTGTCTA TTGTCTACTC TGGGGAAGAT 
GAACCTCGGC TGGCTCCAAG AGGAACTTCT GTCCAGAGTT TTTCTGCTTC TGACATGGAG 
GTTTCCTGGA ATGCCATTGC TTGGAATAGA AACACTGGAA GAGTGCTGGG CTATGAGGTC 
TTATACTGGA CTGACAACTC CAAAGAATCT ATGATTGGGA AAATTAGAGT CAGTGGAAAT 
GTCACAACCA AGAATATTAC AGGGCTAAGA GCTAATACGA TTTACTTTGC TTCTGTGAGA 
GCCTACAACA CTGCAGGGAC AGGACCCTCA AGTCCACCAG TTAATGTCAC CACGAAAAAG 
TCCCCACCTA GCCAACCACC AGCAAACATT GCCTGGAAGC TGTCAAATTC CAAATTATGC 
CTGAACTGGG AGCATGTAAA AACTATGGAA AATGAGTCTG AAGTGCTGGG CTACAAGATC 
CTCTATCGGC AGAACCGACA GAGTAAAACT CATGTCTTGG AAACAAATAA TACATCAGCT 
GAGCTACTGG TTCCATTTGA AGAAGACTAT TTGATCGAAA TCAGAACAGT CAGTGATGGT 
GGAGACGGAA GCAGTAGTGA GGAAATCAGA ATTCCAAAAA TGTCAAGTTT GAGTTCCGTG 
GGAGTTCAGA TCTTGAAGCC CAGTACCCAG TTCCTGACAA TGGTTGGATT TTTTTACTGT 
TTTGTTATTC AGCCACTTTC ACGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Adropin is a brain membrane-bound protein regulating physical activity via the NB-3/Notch signaling pathway in mice.
The Journal of biological chemistry289(37)25976-86(2014 Sep)
Wong CM,Wang Y,Lee JT,Huang Z,Wu D,Xu A,Lam KS

Contribution of the neural cell recognition molecule NB-3 to synapse formation between parallel fibers and Purkinje cells in mouse.
Developmental neurobiology69(12)811-24(2009 Oct)
Sakurai K,Toyoshima M,Ueda H,Matsubara K,Takeda Y,Karagogeos D,Shimoda Y,Watanabe K

NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes.
The Journal of biological chemistry279(24)25858-65(2004 Jun)
Cui XY,Hu QD,Tekaya M,Shimoda Y,Ang BT,Nie DY,Sun L,Hu WP,Karsak M,Duka T,Takeda Y,Ou LY,Dawe GS,Yu FG,Ahmed S,Jin LH,Schachner M,Watanabe K,Arsenijevic Y,Xiao ZC

Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup.
Journal of neurobiology56(3)252-65(2003 Sep)
Takeda Y,Akasaka K,Lee S,Kobayashi S,Kawano H,Murayama S,Takahashi N,Hashimoto K,Kano M,Asano M,Sudo K,Iwakura Y,Watanabe K

Novel neural adhesion molecules in the Contactin/F3 subgroup of the immunoglobulin superfamily: isolation and characterization of cDNAs from rat brain.
Neuroscience letters218(3)173-6(1996 Nov)
Ogawa J,Kaneko H,Masuda T,Nagata S,Hosoya H,Watanabe K