Thrb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Thrb
Entrez Gene ID	24831
Full Name	thyroid hormone receptor beta
Synonyms	C-erba-beta,ERBA2,Nr1a2,RATT3REC,T3rec,TRbeta
General protein information	Preferred Names thyroid hormone receptor beta Names thyroid hormone receptor beta TRbeta2Delta c-erbA-2 nuclear receptor subfamily 1 group A member 2 thyroid hormone receptor beta 3 thyroid hormone receptor beta2delta thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p16
Summary	nuclear hormone receptor for triiodothyronine (T3); mediates the biological activities of thyroid hormone [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012672.3	NP_036804.2	thyroid hormone receptor beta isoform 1
NM_001270854.1	NP_001257783.1	thyroid hormone receptor beta isoform 2
XM_017599580.1	XP_017455069.1	thyroid hormone receptor beta isoform X1
XM_017599581.1	XP_017455070.1	thyroid hormone receptor beta isoform X3
XM_006251709.3	XP_006251771.1	thyroid hormone receptor beta isoform X2

Pathways from BioSystems

Homologies

	THRB	XP_001090554.1
Gallus gallus (chicken)	THRB	NP_001239150.1
Pan troglodytes (chimpanzee)	THRB	XP_001163850.1
Canis lupus familiaris (dog)	THRB	XP_862690.2
Homo sapiens (human)	THRB	NP_001239563.1
Bos taurus (cattle)	THRB	XP_005226243.1
Rattus norvegicus (Norway rat)	Thrb	NP_001257783.1
Danio rerio (zebrafish)	thrb	NP_571415.1
Mus musculus (house mouse)	Thrb	NP_001106888.1
Xenopus tropicalis (tropical clawed frog)	thrb	NP_001039270.1

Gene Ontology
Bibliography

Related articles in PubMed

Thyroid receptor ? involvement in the effects of acute nicotine on hippocampus-dependent memory.
Leach PT, Kenney JW, Connor DA, Gould TJ
Neuropharmacology93155-63(2015 Jun)

Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats.
Frau C, Loi R, Petrelli A, Perra A, Menegon S, Kowalik MA, Pinna S, Leoni VP, Fornari F, Gramantieri L, Ledda-Columbano GM, Giordano S, Columbano A
Hepatology (Baltimore, Md.)61(1)249-59(2015 Jan)

Nuclear corepressors mediate the repression of phospholipase A2 group IIa gene transcription by thyroid hormone.
Sharma P, Thakran S, Deng X, Elam MB, Park EA
The Journal of biological chemistry288(23)16321-33(2013 Jun)

In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue.
Matsen ME, Thaler JP, Wisse BE, Guyenet SJ, Meek TH, Ogimoto K, Cubelo A, Fischer JD, Kaiyala KJ, Schwartz MW, Morton GJ
American journal of physiology. Endocrinology and metabolism304(7)E734-46(2013 Apr)

Protein-disulfide isomerase regulates the thyroid hormone receptor-mediated gene expression via redox factor-1 through thiol reduction-oxidation.
Hashimoto S, Imaoka S
The Journal of biological chemistry288(3)1706-16(2013 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonstrated that Thyroid receptor beta involvement in the effects of acute nicotine on hippocampus-dependent memory
Title: Thyroid receptor ? involvement in the effects of acute nicotine on hippocampus-dependent memory.

down-regulated in hepatocellular carcinoma
Title: Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats.

a novel inverse recruitment mechanism in which liganded TRbeta recruits corepressors to inhibit PLA2g2a expression.
Title: Nuclear corepressors mediate the repression of phospholipase A2 group IIa gene transcription by thyroid hormone.

Although systemic administration of thrb agonist increases energy expenditure and induces further weight loss in STZ-diabetic rats, it neither increased brown adipose tissue glucose uptake nor attenuated diabetic hyperglycemia.
Title: In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue.

Protein-disulfide isomerase regulates the thyroid hormone receptor-mediated gene expression via redox factor-1 through thiol reduction-oxidation.
Title: Protein-disulfide isomerase regulates the thyroid hormone receptor-mediated gene expression via redox factor-1 through thiol reduction-oxidation.

The following Thrb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Thrb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13238	NM_001270854.1 Latest version!	Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa13306	NM_012672.3 Latest version!	Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa13306	XM_017599581.1 Latest version!	Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa36538	XM_006251709.3 Latest version!	Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa58524	XM_017599580.1 Latest version!	Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Thrb ( NM_001270854.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257783.1 Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa13238
Clone ID Related Accession (Same CDS sequence)	NM_001270854.1
Accession Version	NM_001270854.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Rattus norvegicus(Norway rat)
Product	thyroid hormone receptor beta isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07017060.1, AABR07017059.1 and AABR07017058.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J03933.1, J03819.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTCCTA ACAGTATGAC AGAAAATGGC CTTCCAGCCT GGGACAAACA GAAGCCCCAT 
CCAGACCGAG GCCAGGACTG GAAGCTGGTA GGAATGTCCG AAGCCTGCCT GCACAGGAAG 
AGCCATGTGG AGAGGCGTGG TGCATTGAAG AATGAGCAAA CATCCTCACA CCTCATCCAG 
GCCACTTGGG CGAGCTCTAT ATTCCATCTG GATCCAGACG ATGTGAACGA TCAGAGCGTC 
TCAAGCGCCC AGACTTTCCA GACCGAAGAG AAGAAATGTA AAGGGTATAT CCCCAGCTAT 
CTAGACAAGG ATGAGCTCTG CGTAGTGTGC GGGGACAAAG CCACGGGGTA CCACTATCGC 
TGCATCACCT GTGAAGGCTG CAAGGGTTTC TTTAGAAGAA CCATTCAGAA AAGTCTCCAT 
CCATCTTACT CCTGTAAATA TGAAGGGAAG TGCATCATAG ACAAAGTCAC CCGTAACCAG 
TGCCAGGAAT GTCGCTTTAA GAAATGCATC TATGTTGGCA TGGCAACAGA CCTGGTGCTG 
GATGACAGCA AGAGGCTAGC CAAGAGGAAG CTGATAGAAG AGAACCGTGA GAAGAGGCGG 
CGGGAAGAGC TACAGAAATC CATTGGGCAT AAGCCAGAGC CCACGGATGA GGAATGGGAG 
CTCATCAAGA CAGTCACCGA GGCCCACGTG GCCACCAATG CCCAGGGCAG CCACTGGAAG 
CAGAAGCGGA AATTTCTGCC TGAAGACATT GGACAAGCAC CCATTGTGAA CGCCCCGGAA 
GGTGGCAAGG TTGATCTGGA AGCCTTCAGC CATTTTACAA AAATCATCAC ACCAGCAATC 
ACCAGAGTGG TGGATTTCGC CAAAAAGTTG CCCATGTTTT GTGAGCTGCC CTGTGAAGAC 
CAGATCATCC TCCTCAAAGG CTGCTGCATG GAGATCATGT CCCTCCGAGC TGCTGTGCGC 
TATGACCCAG ACAGCGAGAC TCTAACCTTG AATGGGGAAA TGGCAGTGAC ACGGGGCCAG 
CTGAAAAACG GAGGTCTTGG GGTGGTGTCA GATGCGATCT TTGACCTGGG CATGTCTCTG 
TCGTCTTTCA ACCTGGATGA CACGGAGGTT GCCCTGCTTC AAGCCGTCCT GCTGATGTCT 
TCAGATCGCC CAGGGCTAGC TTGTGTTGAG AGAATTGAGA AATACCAAGA CAGTTTCCTG 
TTGGCCTTTG AACACTATAT CAATTACCGG AAGCACCATG TGACACACTT TTGGCCCAAA 
CTCCTGATGA AGGTGACGGA CCTGCGGATG ATTGGAGCGT GCCACGCCAG CCGCTTCCTG 
CACATGAAGG TGGAGTGCCC CACCGAGCTC TTCCCGCCTC TCTTCTTGGA AGTCTTTGAG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257783.1
CDS	254..1639
Translation	MTPNSMTENGLPAWDKQKPHPDRGQDWKLVGMSEACLHRKSHVERRGALKNEQTSSHLIQATWASSIFHLDPDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKSLHPSYSCKYEGKCIIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPDSETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED

Target ORF information:

RefSeq Version	NM_001270854.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270854.1

ORF Insert Sequence:

ATGACTCCTA ACAGTATGAC AGAAAATGGC CTTCCAGCCT GGGACAAACA GAAGCCCCAT 
CCAGACCGAG GCCAGGACTG GAAGCTGGTA GGAATGTCCG AAGCCTGCCT GCACAGGAAG 
AGCCATGTGG AGAGGCGTGG TGCATTGAAG AATGAGCAAA CATCCTCACA CCTCATCCAG 
GCCACTTGGG CGAGCTCTAT ATTCCATCTG GATCCAGACG ATGTGAACGA TCAGAGCGTC 
TCAAGCGCCC AGACTTTCCA GACCGAAGAG AAGAAATGTA AAGGGTATAT CCCCAGCTAT 
CTAGACAAGG ATGAGCTCTG CGTAGTGTGC GGGGACAAAG CCACGGGGTA CCACTATCGC 
TGCATCACCT GTGAAGGCTG CAAGGGTTTC TTTAGAAGAA CCATTCAGAA AAGTCTCCAT 
CCATCTTACT CCTGTAAATA TGAAGGGAAG TGCATCATAG ACAAAGTCAC CCGTAACCAG 
TGCCAGGAAT GTCGCTTTAA GAAATGCATC TATGTTGGCA TGGCAACAGA CCTGGTGCTG 
GATGACAGCA AGAGGCTAGC CAAGAGGAAG CTGATAGAAG AGAACCGTGA GAAGAGGCGG 
CGGGAAGAGC TACAGAAATC CATTGGGCAT AAGCCAGAGC CCACGGATGA GGAATGGGAG 
CTCATCAAGA CAGTCACCGA GGCCCACGTG GCCACCAATG CCCAGGGCAG CCACTGGAAG 
CAGAAGCGGA AATTTCTGCC TGAAGACATT GGACAAGCAC CCATTGTGAA CGCCCCGGAA 
GGTGGCAAGG TTGATCTGGA AGCCTTCAGC CATTTTACAA AAATCATCAC ACCAGCAATC 
ACCAGAGTGG TGGATTTCGC CAAAAAGTTG CCCATGTTTT GTGAGCTGCC CTGTGAAGAC 
CAGATCATCC TCCTCAAAGG CTGCTGCATG GAGATCATGT CCCTCCGAGC TGCTGTGCGC 
TATGACCCAG ACAGCGAGAC TCTAACCTTG AATGGGGAAA TGGCAGTGAC ACGGGGCCAG 
CTGAAAAACG GAGGTCTTGG GGTGGTGTCA GATGCGATCT TTGACCTGGG CATGTCTCTG 
TCGTCTTTCA ACCTGGATGA CACGGAGGTT GCCCTGCTTC AAGCCGTCCT GCTGATGTCT 
TCAGATCGCC CAGGGCTAGC TTGTGTTGAG AGAATTGAGA AATACCAAGA CAGTTTCCTG 
TTGGCCTTTG AACACTATAT CAATTACCGG AAGCACCATG TGACACACTT TTGGCCCAAA 
CTCCTGATGA AGGTGACGGA CCTGCGGATG ATTGGAGCGT GCCACGCCAG CCGCTTCCTG 
CACATGAAGG TGGAGTGCCC CACCGAGCTC TTCCCGCCTC TCTTCTTGGA AGTCTTTGAG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Thrb ( NM_012672.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036804.2 Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa13306
Clone ID Related Accession (Same CDS sequence)	NM_012672.3 , XM_017599581.1
Accession Version	NM_012672.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Rattus norvegicus(Norway rat)
Product	thyroid hormone receptor beta isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07017060.1, AABR07017059.1 and AABR07017058.1. On Aug 4, 2012 this sequence version replaced NM_012672.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTCCTA ACAGTATGAC AGAAAATGGC CTTCCAGCCT GGGACAAACA GAAGCCCCAT 
CCAGACCGAG GCCAGGACTG GAAGCTGGTA GGAATGTCCG AAGCCTGCCT GCACAGGAAG 
AGCCATGTGG AGAGGCGTGG TGCATTGAAG AATGAGCAAA CATCCTCACA CCTCATCCAG 
GCCACTTGGG CGAGCTCTAT ATTCCATCTG GATCCAGACG ATGTGAACGA TCAGAGCGTC 
TCAAGCGCCC AGACTTTCCA GACCGAAGAG AAGAAATGTA AAGGGTATAT CCCCAGCTAT 
CTAGACAAGG ATGAGCTCTG CGTAGTGTGC GGGGACAAAG CCACGGGGTA CCACTATCGC 
TGCATCACCT GTGAAGGCTG CAAGCCTTCT CACACCAGAG ACGAGAAGAC AGGGATTTGG 
TTCCATACAG ACACCAGTTC TACCTCTCTG CATTCGGTCT GGATGTTGTC CTCAAGGCAG 
TGGGACCCTG AGGGTTTCTT TAGAAGAACC ATTCAGAAAA GTCTCCATCC ATCTTACTCC 
TGTAAATATG AAGGGAAGTG CATCATAGAC AAAGTCACCC GTAACCAGTG CCAGGAATGT 
CGCTTTAAGA AATGCATCTA TGTTGGCATG GCAACAGACC TGGTGCTGGA TGACAGCAAG 
AGGCTAGCCA AGAGGAAGCT GATAGAAGAG AACCGTGAGA AGAGGCGGCG GGAAGAGCTA 
CAGAAATCCA TTGGGCATAA GCCAGAGCCC ACGGATGAGG AATGGGAGCT CATCAAGACA 
GTCACCGAGG CCCACGTGGC CACCAATGCC CAGGGCAGCC ACTGGAAGCA GAAGCGGAAA 
TTTCTGCCTG AAGACATTGG ACAAGCACCC ATTGTGAACG CCCCGGAAGG TGGCAAGGTT 
GATCTGGAAG CCTTCAGCCA TTTTACAAAA ATCATCACAC CAGCAATCAC CAGAGTGGTG 
GATTTCGCCA AAAAGTTGCC CATGTTTTGT GAGCTGCCCT GTGAAGACCA GATCATCCTC 
CTCAAAGGCT GCTGCATGGA GATCATGTCC CTCCGAGCTG CTGTGCGCTA TGACCCAGAC 
AGCGAGACTC TAACCTTGAA TGGGGAAATG GCAGTGACAC GGGGCCAGCT GAAAAACGGA 
GGTCTTGGGG TGGTGTCAGA TGCGATCTTT GACCTGGGCA TGTCTCTGTC GTCTTTCAAC 
CTGGATGACA CGGAGGTTGC CCTGCTTCAA GCCGTCCTGC TGATGTCTTC AGATCGCCCA 
GGGCTAGCTT GTGTTGAGAG AATTGAGAAA TACCAAGACA GTTTCCTGTT GGCCTTTGAA 
CACTATATCA ATTACCGGAA GCACCATGTG ACACACTTTT GGCCCAAACT CCTGATGAAG 
GTGACGGACC TGCGGATGAT TGGAGCGTGC CACGCCAGCC GCTTCCTGCA CATGAAGGTG 
GAGTGCCCCA CCGAGCTCTT CCCGCCTCTC TTCTTGGAAG TCTTTGAGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036804.2
CDS	254..1747
Translation	MTPNSMTENGLPAWDKQKPHPDRGQDWKLVGMSEACLHRKSHVERRGALKNEQTSSHLIQATWASSIFHLDPDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKPSHTRDEKTGIWFHTDTSSTSLHSVWMLSSRQWDPEGFFRRTIQKSLHPSYSCKYEGKCIIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPDSETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED

Target ORF information:

RefSeq Version	NM_012672.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012672.3

ORF Insert Sequence:

ATGACTCCTA ACAGTATGAC AGAAAATGGC CTTCCAGCCT GGGACAAACA GAAGCCCCAT 
CCAGACCGAG GCCAGGACTG GAAGCTGGTA GGAATGTCCG AAGCCTGCCT GCACAGGAAG 
AGCCATGTGG AGAGGCGTGG TGCATTGAAG AATGAGCAAA CATCCTCACA CCTCATCCAG 
GCCACTTGGG CGAGCTCTAT ATTCCATCTG GATCCAGACG ATGTGAACGA TCAGAGCGTC 
TCAAGCGCCC AGACTTTCCA GACCGAAGAG AAGAAATGTA AAGGGTATAT CCCCAGCTAT 
CTAGACAAGG ATGAGCTCTG CGTAGTGTGC GGGGACAAAG CCACGGGGTA CCACTATCGC 
TGCATCACCT GTGAAGGCTG CAAGCCTTCT CACACCAGAG ACGAGAAGAC AGGGATTTGG 
TTCCATACAG ACACCAGTTC TACCTCTCTG CATTCGGTCT GGATGTTGTC CTCAAGGCAG 
TGGGACCCTG AGGGTTTCTT TAGAAGAACC ATTCAGAAAA GTCTCCATCC ATCTTACTCC 
TGTAAATATG AAGGGAAGTG CATCATAGAC AAAGTCACCC GTAACCAGTG CCAGGAATGT 
CGCTTTAAGA AATGCATCTA TGTTGGCATG GCAACAGACC TGGTGCTGGA TGACAGCAAG 
AGGCTAGCCA AGAGGAAGCT GATAGAAGAG AACCGTGAGA AGAGGCGGCG GGAAGAGCTA 
CAGAAATCCA TTGGGCATAA GCCAGAGCCC ACGGATGAGG AATGGGAGCT CATCAAGACA 
GTCACCGAGG CCCACGTGGC CACCAATGCC CAGGGCAGCC ACTGGAAGCA GAAGCGGAAA 
TTTCTGCCTG AAGACATTGG ACAAGCACCC ATTGTGAACG CCCCGGAAGG TGGCAAGGTT 
GATCTGGAAG CCTTCAGCCA TTTTACAAAA ATCATCACAC CAGCAATCAC CAGAGTGGTG 
GATTTCGCCA AAAAGTTGCC CATGTTTTGT GAGCTGCCCT GTGAAGACCA GATCATCCTC 
CTCAAAGGCT GCTGCATGGA GATCATGTCC CTCCGAGCTG CTGTGCGCTA TGACCCAGAC 
AGCGAGACTC TAACCTTGAA TGGGGAAATG GCAGTGACAC GGGGCCAGCT GAAAAACGGA 
GGTCTTGGGG TGGTGTCAGA TGCGATCTTT GACCTGGGCA TGTCTCTGTC GTCTTTCAAC 
CTGGATGACA CGGAGGTTGC CCTGCTTCAA GCCGTCCTGC TGATGTCTTC AGATCGCCCA 
GGGCTAGCTT GTGTTGAGAG AATTGAGAAA TACCAAGACA GTTTCCTGTT GGCCTTTGAA 
CACTATATCA ATTACCGGAA GCACCATGTG ACACACTTTT GGCCCAAACT CCTGATGAAG 
GTGACGGACC TGCGGATGAT TGGAGCGTGC CACGCCAGCC GCTTCCTGCA CATGAAGGTG 
GAGTGCCCCA CCGAGCTCTT CCCGCCTCTC TTCTTGGAAG TCTTTGAGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Thrb ( XM_017599581.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455070.1 Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa13306
Clone ID Related Accession (Same CDS sequence)	NM_012672.3 , XM_017599581.1
Accession Version	XM_017599581.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	thyroid hormone receptor beta isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTCCTA ACAGTATGAC AGAAAATGGC CTTCCAGCCT GGGACAAACA GAAGCCCCAT 
CCAGACCGAG GCCAGGACTG GAAGCTGGTA GGAATGTCCG AAGCCTGCCT GCACAGGAAG 
AGCCATGTGG AGAGGCGTGG TGCATTGAAG AATGAGCAAA CATCCTCACA CCTCATCCAG 
GCCACTTGGG CGAGCTCTAT ATTCCATCTG GATCCAGACG ATGTGAACGA TCAGAGCGTC 
TCAAGCGCCC AGACTTTCCA GACCGAAGAG AAGAAATGTA AAGGGTATAT CCCCAGCTAT 
CTAGACAAGG ATGAGCTCTG CGTAGTGTGC GGGGACAAAG CCACGGGGTA CCACTATCGC 
TGCATCACCT GTGAAGGCTG CAAGCCTTCT CACACCAGAG ACGAGAAGAC AGGGATTTGG 
TTCCATACAG ACACCAGTTC TACCTCTCTG CATTCGGTCT GGATGTTGTC CTCAAGGCAG 
TGGGACCCTG AGGGTTTCTT TAGAAGAACC ATTCAGAAAA GTCTCCATCC ATCTTACTCC 
TGTAAATATG AAGGGAAGTG CATCATAGAC AAAGTCACCC GTAACCAGTG CCAGGAATGT 
CGCTTTAAGA AATGCATCTA TGTTGGCATG GCAACAGACC TGGTGCTGGA TGACAGCAAG 
AGGCTAGCCA AGAGGAAGCT GATAGAAGAG AACCGTGAGA AGAGGCGGCG GGAAGAGCTA 
CAGAAATCCA TTGGGCATAA GCCAGAGCCC ACGGATGAGG AATGGGAGCT CATCAAGACA 
GTCACCGAGG CCCACGTGGC CACCAATGCC CAGGGCAGCC ACTGGAAGCA GAAGCGGAAA 
TTTCTGCCTG AAGACATTGG ACAAGCACCC ATTGTGAACG CCCCGGAAGG TGGCAAGGTT 
GATCTGGAAG CCTTCAGCCA TTTTACAAAA ATCATCACAC CAGCAATCAC CAGAGTGGTG 
GATTTCGCCA AAAAGTTGCC CATGTTTTGT GAGCTGCCCT GTGAAGACCA GATCATCCTC 
CTCAAAGGCT GCTGCATGGA GATCATGTCC CTCCGAGCTG CTGTGCGCTA TGACCCAGAC 
AGCGAGACTC TAACCTTGAA TGGGGAAATG GCAGTGACAC GGGGCCAGCT GAAAAACGGA 
GGTCTTGGGG TGGTGTCAGA TGCGATCTTT GACCTGGGCA TGTCTCTGTC GTCTTTCAAC 
CTGGATGACA CGGAGGTTGC CCTGCTTCAA GCCGTCCTGC TGATGTCTTC AGATCGCCCA 
GGGCTAGCTT GTGTTGAGAG AATTGAGAAA TACCAAGACA GTTTCCTGTT GGCCTTTGAA 
CACTATATCA ATTACCGGAA GCACCATGTG ACACACTTTT GGCCCAAACT CCTGATGAAG 
GTGACGGACC TGCGGATGAT TGGAGCGTGC CACGCCAGCC GCTTCCTGCA CATGAAGGTG 
GAGTGCCCCA CCGAGCTCTT CCCGCCTCTC TTCTTGGAAG TCTTTGAGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455070.1
CDS	375..1868
Translation	MTPNSMTENGLPAWDKQKPHPDRGQDWKLVGMSEACLHRKSHVERRGALKNEQTSSHLIQATWASSIFHLDPDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKPSHTRDEKTGIWFHTDTSSTSLHSVWMLSSRQWDPEGFFRRTIQKSLHPSYSCKYEGKCIIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPDSETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED

Target ORF information:

RefSeq Version	XM_017599581.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599581.1

ORF Insert Sequence:

ATGACTCCTA ACAGTATGAC AGAAAATGGC CTTCCAGCCT GGGACAAACA GAAGCCCCAT 
CCAGACCGAG GCCAGGACTG GAAGCTGGTA GGAATGTCCG AAGCCTGCCT GCACAGGAAG 
AGCCATGTGG AGAGGCGTGG TGCATTGAAG AATGAGCAAA CATCCTCACA CCTCATCCAG 
GCCACTTGGG CGAGCTCTAT ATTCCATCTG GATCCAGACG ATGTGAACGA TCAGAGCGTC 
TCAAGCGCCC AGACTTTCCA GACCGAAGAG AAGAAATGTA AAGGGTATAT CCCCAGCTAT 
CTAGACAAGG ATGAGCTCTG CGTAGTGTGC GGGGACAAAG CCACGGGGTA CCACTATCGC 
TGCATCACCT GTGAAGGCTG CAAGCCTTCT CACACCAGAG ACGAGAAGAC AGGGATTTGG 
TTCCATACAG ACACCAGTTC TACCTCTCTG CATTCGGTCT GGATGTTGTC CTCAAGGCAG 
TGGGACCCTG AGGGTTTCTT TAGAAGAACC ATTCAGAAAA GTCTCCATCC ATCTTACTCC 
TGTAAATATG AAGGGAAGTG CATCATAGAC AAAGTCACCC GTAACCAGTG CCAGGAATGT 
CGCTTTAAGA AATGCATCTA TGTTGGCATG GCAACAGACC TGGTGCTGGA TGACAGCAAG 
AGGCTAGCCA AGAGGAAGCT GATAGAAGAG AACCGTGAGA AGAGGCGGCG GGAAGAGCTA 
CAGAAATCCA TTGGGCATAA GCCAGAGCCC ACGGATGAGG AATGGGAGCT CATCAAGACA 
GTCACCGAGG CCCACGTGGC CACCAATGCC CAGGGCAGCC ACTGGAAGCA GAAGCGGAAA 
TTTCTGCCTG AAGACATTGG ACAAGCACCC ATTGTGAACG CCCCGGAAGG TGGCAAGGTT 
GATCTGGAAG CCTTCAGCCA TTTTACAAAA ATCATCACAC CAGCAATCAC CAGAGTGGTG 
GATTTCGCCA AAAAGTTGCC CATGTTTTGT GAGCTGCCCT GTGAAGACCA GATCATCCTC 
CTCAAAGGCT GCTGCATGGA GATCATGTCC CTCCGAGCTG CTGTGCGCTA TGACCCAGAC 
AGCGAGACTC TAACCTTGAA TGGGGAAATG GCAGTGACAC GGGGCCAGCT GAAAAACGGA 
GGTCTTGGGG TGGTGTCAGA TGCGATCTTT GACCTGGGCA TGTCTCTGTC GTCTTTCAAC 
CTGGATGACA CGGAGGTTGC CCTGCTTCAA GCCGTCCTGC TGATGTCTTC AGATCGCCCA 
GGGCTAGCTT GTGTTGAGAG AATTGAGAAA TACCAAGACA GTTTCCTGTT GGCCTTTGAA 
CACTATATCA ATTACCGGAA GCACCATGTG ACACACTTTT GGCCCAAACT CCTGATGAAG 
GTGACGGACC TGCGGATGAT TGGAGCGTGC CACGCCAGCC GCTTCCTGCA CATGAAGGTG 
GAGTGCCCCA CCGAGCTCTT CCCGCCTCTC TTCTTGGAAG TCTTTGAGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Thrb ( XM_006251709.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006251771.1 Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant X2, mRNA.

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CloneID	ORa36538
Clone ID Related Accession (Same CDS sequence)	XM_006251709.3
Accession Version	XM_006251709.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	thyroid hormone receptor beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251709.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGTATGG ATGTACGCTG TCCCAGTATA TGCACTGCTC CGGGGAGCAG GGGGCTGGCA 
AGTGCGTGCA TGGAGCGTGT GTGTATATGT AAAGCAGGAC TGCACCTGGA TACCAAAATG 
AACTACTGCG TGCCAGAGGT ACACGAAGTG TGCCCAGCTG CCGGCAGCAA CCGTTACATG 
CAGGTCACTG ACTACCTCGC GTATCTGGAA GACAGTCCGG CTTACAGTGG CTGCGATGTC 
CAAGCTGTGC CCGGTAGCAG CATATATCTG GAACAGGCCT GGACTCTGAA TCAGCCTTAT 
ACCTGTAGTT ACCCTGGAAA CCTGTTTAAA AGCAAGGACT CTGACTTGGA CATGGCCCTG 
AGTCAGTACA GCCAGCCTGC ACATCTCCCC GAAGAAAAGC CTTTTCCTCA AGTGCGGTCG 
CCTCCGCACT CACACAAAAA AGGGTATATC CCCAGCTATC TAGACAAGGA TGAGCTCTGC 
GTAGTGTGCG GGGACAAAGC CACGGGGTAC CACTATCGCT GCATCACCTG TGAAGGCTGC 
AAGGGTTTCT TTAGAAGAAC CATTCAGAAA AGTCTCCATC CATCTTACTC CTGTAAATAT 
GAAGGGAAGT GCATCATAGA CAAAGTCACC CGTAACCAGT GCCAGGAATG TCGCTTTAAG 
AAATGCATCT ATGTTGGCAT GGCAACAGAC CTGGTGCTGG ATGACAGCAA GAGGCTAGCC 
AAGAGGAAGC TGATAGAAGA GAACCGTGAG AAGAGGCGGC GGGAAGAGCT ACAGAAATCC 
ATTGGGCATA AGCCAGAGCC CACGGATGAG GAATGGGAGC TCATCAAGAC AGTCACCGAG 
GCCCACGTGG CCACCAATGC CCAGGGCAGC CACTGGAAGC AGAAGCGGAA ATTTCTGCCT 
GAAGACATTG GACAAGCACC CATTGTGAAC GCCCCGGAAG GTGGCAAGGT TGATCTGGAA 
GCCTTCAGCC ATTTTACAAA AATCATCACA CCAGCAATCA CCAGAGTGGT GGATTTCGCC 
AAAAAGTTGC CCATGTTTTG TGAGCTGCCC TGTGAAGACC AGATCATCCT CCTCAAAGGC 
TGCTGCATGG AGATCATGTC CCTCCGAGCT GCTGTGCGCT ATGACCCAGA CAGCGAGACT 
CTAACCTTGA ATGGGGAAAT GGCAGTGACA CGGGGCCAGC TGAAAAACGG AGGTCTTGGG 
GTGGTGTCAG ATGCGATCTT TGACCTGGGC ATGTCTCTGT CGTCTTTCAA CCTGGATGAC 
ACGGAGGTTG CCCTGCTTCA AGCCGTCCTG CTGATGTCTT CAGATCGCCC AGGGCTAGCT 
TGTGTTGAGA GAATTGAGAA ATACCAAGAC AGTTTCCTGT TGGCCTTTGA ACACTATATC 
AATTACCGGA AGCACCATGT GACACACTTT TGGCCCAAAC TCCTGATGAA GGTGACGGAC 
CTGCGGATGA TTGGAGCGTG CCACGCCAGC CGCTTCCTGC ACATGAAGGT GGAGTGCCCC 
ACCGAGCTCT TCCCGCCTCT CTTCTTGGAA GTCTTTGAGG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006251771.1
CDS	110..1654
Translation	MCMDVRCPSICTAPGSRGLASACMERVCICKAGLHLDTKMNYCVPEVHEVCPAAGSNRYMQVTDYLAYLEDSPAYSGCDVQAVPGSSIYLEQAWTLNQPYTCSYPGNLFKSKDSDLDMALSQYSQPAHLPEEKPFPQVRSPPHSHKKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKSLHPSYSCKYEGKCIIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPDSETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED

Target ORF information:

RefSeq Version	XM_006251709.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006251709.3

ORF Insert Sequence:

ATGTGTATGG ATGTACGCTG TCCCAGTATA TGCACTGCTC CGGGGAGCAG GGGGCTGGCA 
AGTGCGTGCA TGGAGCGTGT GTGTATATGT AAAGCAGGAC TGCACCTGGA TACCAAAATG 
AACTACTGCG TGCCAGAGGT ACACGAAGTG TGCCCAGCTG CCGGCAGCAA CCGTTACATG 
CAGGTCACTG ACTACCTCGC GTATCTGGAA GACAGTCCGG CTTACAGTGG CTGCGATGTC 
CAAGCTGTGC CCGGTAGCAG CATATATCTG GAACAGGCCT GGACTCTGAA TCAGCCTTAT 
ACCTGTAGTT ACCCTGGAAA CCTGTTTAAA AGCAAGGACT CTGACTTGGA CATGGCCCTG 
AGTCAGTACA GCCAGCCTGC ACATCTCCCC GAAGAAAAGC CTTTTCCTCA AGTGCGGTCG 
CCTCCGCACT CACACAAAAA AGGGTATATC CCCAGCTATC TAGACAAGGA TGAGCTCTGC 
GTAGTGTGCG GGGACAAAGC CACGGGGTAC CACTATCGCT GCATCACCTG TGAAGGCTGC 
AAGGGTTTCT TTAGAAGAAC CATTCAGAAA AGTCTCCATC CATCTTACTC CTGTAAATAT 
GAAGGGAAGT GCATCATAGA CAAAGTCACC CGTAACCAGT GCCAGGAATG TCGCTTTAAG 
AAATGCATCT ATGTTGGCAT GGCAACAGAC CTGGTGCTGG ATGACAGCAA GAGGCTAGCC 
AAGAGGAAGC TGATAGAAGA GAACCGTGAG AAGAGGCGGC GGGAAGAGCT ACAGAAATCC 
ATTGGGCATA AGCCAGAGCC CACGGATGAG GAATGGGAGC TCATCAAGAC AGTCACCGAG 
GCCCACGTGG CCACCAATGC CCAGGGCAGC CACTGGAAGC AGAAGCGGAA ATTTCTGCCT 
GAAGACATTG GACAAGCACC CATTGTGAAC GCCCCGGAAG GTGGCAAGGT TGATCTGGAA 
GCCTTCAGCC ATTTTACAAA AATCATCACA CCAGCAATCA CCAGAGTGGT GGATTTCGCC 
AAAAAGTTGC CCATGTTTTG TGAGCTGCCC TGTGAAGACC AGATCATCCT CCTCAAAGGC 
TGCTGCATGG AGATCATGTC CCTCCGAGCT GCTGTGCGCT ATGACCCAGA CAGCGAGACT 
CTAACCTTGA ATGGGGAAAT GGCAGTGACA CGGGGCCAGC TGAAAAACGG AGGTCTTGGG 
GTGGTGTCAG ATGCGATCTT TGACCTGGGC ATGTCTCTGT CGTCTTTCAA CCTGGATGAC 
ACGGAGGTTG CCCTGCTTCA AGCCGTCCTG CTGATGTCTT CAGATCGCCC AGGGCTAGCT 
TGTGTTGAGA GAATTGAGAA ATACCAAGAC AGTTTCCTGT TGGCCTTTGA ACACTATATC 
AATTACCGGA AGCACCATGT GACACACTTT TGGCCCAAAC TCCTGATGAA GGTGACGGAC 
CTGCGGATGA TTGGAGCGTG CCACGCCAGC CGCTTCCTGC ACATGAAGGT GGAGTGCCCC 
ACCGAGCTCT TCCCGCCTCT CTTCTTGGAA GTCTTTGAGG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Thrb ( XM_017599580.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455069.1 Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa58524
Clone ID Related Accession (Same CDS sequence)	XM_017599580.1
Accession Version	XM_017599580.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1653bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	thyroid hormone receptor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGTATGG ATGTACGCTG TCCCAGTATA TGCACTGCTC CGGGGAGCAG GGGGCTGGCA 
AGTGCGTGCA TGGAGCGTGT GTGTATATGT AAAGCAGGAC TGCACCTGGA TACCAAAATG 
AACTACTGCG TGCCAGAGGT ACACGAAGTG TGCCCAGCTG CCGGCAGCAA CCGTTACATG 
CAGGTCACTG ACTACCTCGC GTATCTGGAA GACAGTCCGG CTTACAGTGG CTGCGATGTC 
CAAGCTGTGC CCGGTAGCAG CATATATCTG GAACAGGCCT GGACTCTGAA TCAGCCTTAT 
ACCTGTAGTT ACCCTGGAAA CCTGTTTAAA AGCAAGGACT CTGACTTGGA CATGGCCCTG 
AGTCAGTACA GCCAGCCTGC ACATCTCCCC GAAGAAAAGC CTTTTCCTCA AGTGCGGTCG 
CCTCCGCACT CACACAAAAA AGGGTATATC CCCAGCTATC TAGACAAGGA TGAGCTCTGC 
GTAGTGTGCG GGGACAAAGC CACGGGGTAC CACTATCGCT GCATCACCTG TGAAGGCTGC 
AAGCCTTCTC ACACCAGAGA CGAGAAGACA GGGATTTGGT TCCATACAGA CACCAGTTCT 
ACCTCTCTGC ATTCGGTCTG GATGTTGTCC TCAAGGCAGT GGGACCCTGA GGGTTTCTTT 
AGAAGAACCA TTCAGAAAAG TCTCCATCCA TCTTACTCCT GTAAATATGA AGGGAAGTGC 
ATCATAGACA AAGTCACCCG TAACCAGTGC CAGGAATGTC GCTTTAAGAA ATGCATCTAT 
GTTGGCATGG CAACAGACCT GGTGCTGGAT GACAGCAAGA GGCTAGCCAA GAGGAAGCTG 
ATAGAAGAGA ACCGTGAGAA GAGGCGGCGG GAAGAGCTAC AGAAATCCAT TGGGCATAAG 
CCAGAGCCCA CGGATGAGGA ATGGGAGCTC ATCAAGACAG TCACCGAGGC CCACGTGGCC 
ACCAATGCCC AGGGCAGCCA CTGGAAGCAG AAGCGGAAAT TTCTGCCTGA AGACATTGGA 
CAAGCACCCA TTGTGAACGC CCCGGAAGGT GGCAAGGTTG ATCTGGAAGC CTTCAGCCAT 
TTTACAAAAA TCATCACACC AGCAATCACC AGAGTGGTGG ATTTCGCCAA AAAGTTGCCC 
ATGTTTTGTG AGCTGCCCTG TGAAGACCAG ATCATCCTCC TCAAAGGCTG CTGCATGGAG 
ATCATGTCCC TCCGAGCTGC TGTGCGCTAT GACCCAGACA GCGAGACTCT AACCTTGAAT 
GGGGAAATGG CAGTGACACG GGGCCAGCTG AAAAACGGAG GTCTTGGGGT GGTGTCAGAT 
GCGATCTTTG ACCTGGGCAT GTCTCTGTCG TCTTTCAACC TGGATGACAC GGAGGTTGCC 
CTGCTTCAAG CCGTCCTGCT GATGTCTTCA GATCGCCCAG GGCTAGCTTG TGTTGAGAGA 
ATTGAGAAAT ACCAAGACAG TTTCCTGTTG GCCTTTGAAC ACTATATCAA TTACCGGAAG 
CACCATGTGA CACACTTTTG GCCCAAACTC CTGATGAAGG TGACGGACCT GCGGATGATT 
GGAGCGTGCC ACGCCAGCCG CTTCCTGCAC ATGAAGGTGG AGTGCCCCAC CGAGCTCTTC 
CCGCCTCTCT TCTTGGAAGT CTTTGAGGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455069.1
CDS	112..1764
Translation	MCMDVRCPSICTAPGSRGLASACMERVCICKAGLHLDTKMNYCVPEVHEVCPAAGSNRYMQVTDYLAYLEDSPAYSGCDVQAVPGSSIYLEQAWTLNQPYTCSYPGNLFKSKDSDLDMALSQYSQPAHLPEEKPFPQVRSPPHSHKKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKPSHTRDEKTGIWFHTDTSSTSLHSVWMLSSRQWDPEGFFRRTIQKSLHPSYSCKYEGKCIIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPDSETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED

Target ORF information:

RefSeq Version	XM_017599580.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus thyroid hormone receptor beta (Thrb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599580.1

ORF Insert Sequence:

ATGTGTATGG ATGTACGCTG TCCCAGTATA TGCACTGCTC CGGGGAGCAG GGGGCTGGCA 
AGTGCGTGCA TGGAGCGTGT GTGTATATGT AAAGCAGGAC TGCACCTGGA TACCAAAATG 
AACTACTGCG TGCCAGAGGT ACACGAAGTG TGCCCAGCTG CCGGCAGCAA CCGTTACATG 
CAGGTCACTG ACTACCTCGC GTATCTGGAA GACAGTCCGG CTTACAGTGG CTGCGATGTC 
CAAGCTGTGC CCGGTAGCAG CATATATCTG GAACAGGCCT GGACTCTGAA TCAGCCTTAT 
ACCTGTAGTT ACCCTGGAAA CCTGTTTAAA AGCAAGGACT CTGACTTGGA CATGGCCCTG 
AGTCAGTACA GCCAGCCTGC ACATCTCCCC GAAGAAAAGC CTTTTCCTCA AGTGCGGTCG 
CCTCCGCACT CACACAAAAA AGGGTATATC CCCAGCTATC TAGACAAGGA TGAGCTCTGC 
GTAGTGTGCG GGGACAAAGC CACGGGGTAC CACTATCGCT GCATCACCTG TGAAGGCTGC 
AAGCCTTCTC ACACCAGAGA CGAGAAGACA GGGATTTGGT TCCATACAGA CACCAGTTCT 
ACCTCTCTGC ATTCGGTCTG GATGTTGTCC TCAAGGCAGT GGGACCCTGA GGGTTTCTTT 
AGAAGAACCA TTCAGAAAAG TCTCCATCCA TCTTACTCCT GTAAATATGA AGGGAAGTGC 
ATCATAGACA AAGTCACCCG TAACCAGTGC CAGGAATGTC GCTTTAAGAA ATGCATCTAT 
GTTGGCATGG CAACAGACCT GGTGCTGGAT GACAGCAAGA GGCTAGCCAA GAGGAAGCTG 
ATAGAAGAGA ACCGTGAGAA GAGGCGGCGG GAAGAGCTAC AGAAATCCAT TGGGCATAAG 
CCAGAGCCCA CGGATGAGGA ATGGGAGCTC ATCAAGACAG TCACCGAGGC CCACGTGGCC 
ACCAATGCCC AGGGCAGCCA CTGGAAGCAG AAGCGGAAAT TTCTGCCTGA AGACATTGGA 
CAAGCACCCA TTGTGAACGC CCCGGAAGGT GGCAAGGTTG ATCTGGAAGC CTTCAGCCAT 
TTTACAAAAA TCATCACACC AGCAATCACC AGAGTGGTGG ATTTCGCCAA AAAGTTGCCC 
ATGTTTTGTG AGCTGCCCTG TGAAGACCAG ATCATCCTCC TCAAAGGCTG CTGCATGGAG 
ATCATGTCCC TCCGAGCTGC TGTGCGCTAT GACCCAGACA GCGAGACTCT AACCTTGAAT 
GGGGAAATGG CAGTGACACG GGGCCAGCTG AAAAACGGAG GTCTTGGGGT GGTGTCAGAT 
GCGATCTTTG ACCTGGGCAT GTCTCTGTCG TCTTTCAACC TGGATGACAC GGAGGTTGCC 
CTGCTTCAAG CCGTCCTGCT GATGTCTTCA GATCGCCCAG GGCTAGCTTG TGTTGAGAGA 
ATTGAGAAAT ACCAAGACAG TTTCCTGTTG GCCTTTGAAC ACTATATCAA TTACCGGAAG 
CACCATGTGA CACACTTTTG GCCCAAACTC CTGATGAAGG TGACGGACCT GCGGATGATT 
GGAGCGTGCC ACGCCAGCCG CTTCCTGCAC ATGAAGGTGG AGTGCCCCAC CGAGCTCTTC 
CCGCCTCTCT TCTTGGAAGT CTTTGAGGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Thyroid receptor ? involvement in the effects of acute nicotine on hippocampus-dependent memory.
Neuropharmacology93155-63(2015 Jun)
Leach PT,Kenney JW,Connor DA,Gould TJ

Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats.
Hepatology (Baltimore, Md.)61(1)249-59(2015 Jan)
Frau C,Loi R,Petrelli A,Perra A,Menegon S,Kowalik MA,Pinna S,Leoni VP,Fornari F,Gramantieri L,Ledda-Columbano GM,Giordano S,Columbano A

Nuclear corepressors mediate the repression of phospholipase A2 group IIa gene transcription by thyroid hormone.
The Journal of biological chemistry288(23)16321-33(2013 Jun)
Sharma P,Thakran S,Deng X,Elam MB,Park EA

In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue.
American journal of physiology. Endocrinology and metabolism304(7)E734-46(2013 Apr)
Matsen ME,Thaler JP,Wisse BE,Guyenet SJ,Meek TH,Ogimoto K,Cubelo A,Fischer JD,Kaiyala KJ,Schwartz MW,Morton GJ

Protein-disulfide isomerase regulates the thyroid hormone receptor-mediated gene expression via redox factor-1 through thiol reduction-oxidation.
The Journal of biological chemistry288(3)1706-16(2013 Jan)
Hashimoto S,Imaoka S

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Thrb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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