Eif4e cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eif4e
Entrez Gene ID	117045
Full Name	eukaryotic translation initiation factor 4E
General protein information	Preferred Names eukaryotic translation initiation factor 4E Names eukaryotic translation initiation factor 4E eIF-4E eIF-4F 25 kDa subunit eukaryotic initiation factor 4E mRNA cap-binding protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q44
Summary	binds to the mRNA 7-methylguanosine cap and mediates mRNA binding to the 40S ribosome in the rate limiting step in translational initiation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008761488.2	XP_008759710.1	eukaryotic translation initiation factor 4E isoform X1
NM_053974.2	NP_446426.1	eukaryotic translation initiation factor 4E
XM_017590592.1	XP_017446081.1	eukaryotic translation initiation factor 4E isoform X2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	EIF4E	XP_005639275.1
Rattus norvegicus (Norway rat)	Eif4e	NP_446426.1
Danio rerio (zebrafish)	eif4ea	NP_571808.1
Drosophila melanogaster (fruit fly)	eIF4E-5	NP_648160.2
Danio rerio (zebrafish)	eif4eb	NP_001007778.1
Xenopus tropicalis (tropical clawed frog)	eif4e	NP_001015909.1
Homo sapiens (human)	EIF4E	NP_001124151.1
Bos taurus (cattle)	EIF4E	NP_776735.2
Mus musculus (house mouse)	Eif4e	NP_031943.3
Drosophila melanogaster (fruit fly)	eIF4E-3	NP_648194.1
Pan troglodytes (chimpanzee)	EIF4E	NP_001233399.1
	EIF4E	XP_001104976.1
Drosophila melanogaster (fruit fly)	eIF-4E	NP_729485.1
Drosophila melanogaster (fruit fly)	eIF4E-7	NP_726718.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007172	XP_001688027.1
Arabidopsis thaliana (thale cress)	EIF4E	NP_193538.1
Gallus gallus (chicken)	EIF4E	XP_420655.4
Drosophila melanogaster (fruit fly)	eIF4E-4	NP_648052.1
Caenorhabditis elegans (roundworm)	ife-3	NP_503124.1
Oryza sativa (rice)	Os01g0970400	NP_001045525.1

Gene Ontology
Bibliography

Related articles in PubMed

Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis.
Zhou Q, Liu C, Liu W, Zhang H, Zhang R, Liu J, Zhang J, Xu C, Liu L, Huang S, Chen L
Toxicological sciences : an official journal of the Society of Toxicology143(1)81-96(2015 Jan)

Dissociation of eIF4E-binding protein 2 (4E-BP2) from eIF4E independent of Thr37/Thr46 phosphorylation in the ischemic stress response.
Ayuso MI, Martinez-Alonso E, Salvador N, Bonova P, Regidor I, Alc?zar A
PloS one10(3)e0121958(2015)

An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program.
Yang G, Smibert CA, Kaplan DR, Miller FD
Neuron84(4)723-39(2014 Nov)

Requirement of Mammalian target of rapamycin complex 1 downstream effectors in cued fear memory reconsolidation and its persistence.
Huynh TN, Santini E, Klann E
The Journal of neuroscience : the official journal of the Society for Neuroscience34(27)9034-9(2014 Jul)

The scanning mechanism of eukaryotic translation initiation.
Hinnebusch AG
Annual review of biochemistry83779-812(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, resulting in caspase-dependent and -independent apoptosis in neuronal cells.
Title: Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis.

Cerebral ischemia and subsequent reperfusion induced dephosphorylation and phosphorylation of 4E-BP2 at Thr37/Thr46. The induced phosphorylation coincided with the release of 4E-BP2 from eIF4E, although two phosphorylated 4E-BP2 forms were bound to eIF4E.
Title: Dissociation of eIF4E-binding protein 2 (4E-BP2) from eIF4E independent of Thr37/Thr46 phosphorylation in the ischemic stress response.

TGFbeta induces signaling involving PI3kinase-dependent Mnk-1-mediated phosphorylation of eIF4E at Ser-209 to facilitate mesangial cell hypertrophy. A role for dissociation of 4EBP-1-eIF4E complex for Mnk-1-mediated phosphorylation of eIF4E.
Title: TGF?-induced PI 3 kinase-dependent Mnk-1 activation is necessary for Ser-209 phosphorylation of eIF4E and mesangial cell hypertrophy.

Expression of eIF4E in hippocampus is higher in vascular dementia treated with electroacupuncture compared to untreated.
Title: Effect of electroacupuncture on the expression of mTOR and eIF4E in hippocampus of rats with vascular dementia.

the eIF4E-eIF4G complex is more stringently required for plasticity induced by initial learning than for that triggered by reactivation of an existing memory.
Title: Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation.

The following Eif4e gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif4e cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12530	NM_053974.2 Latest version!	Rattus norvegicus eukaryotic translation initiation factor 4E (Eif4e), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa12530	XM_008761488.2 Latest version!	Rattus norvegicus eukaryotic translation initiation factor 4E (Eif4e), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa59594	XM_017590592.1 Latest version!	Rattus norvegicus eukaryotic translation initiation factor 4E (Eif4e), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eif4e ( NM_053974.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446426.1 Rattus norvegicus eukaryotic translation initiation factor 4E (Eif4e), mRNA.

Price & Availability↑

CloneID	ORa12530
Clone ID Related Accession (Same CDS sequence)	XM_008761488.2 , NM_053974.2
Accession Version	NM_053974.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	eukaryotic translation initiation factor 4E
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC087001.1. On Dec 26, 2004 this sequence version replaced NM_053974.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC087001.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGACTG TGGAACCGGA AACCACCCCT ACCACTAATC CCCCACCTGC GGAAGAGGAA 
AAAACAGAGT CTAATCAGGA GGTTGCTAAT CCAGAGCACT ATATTAAACA CCCTCTACAG 
AACAGGTGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTT 
CGGTTGATCT CTAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTATACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAGCAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TGCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGACGTGTGT GGAGCTGTTG TCAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC GACTGAATGT GAAAACAGAG ATGCAGTCAC ACACATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCGAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACAAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446426.1
CDS	14..667
Translation	MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Target ORF information:

RefSeq Version	NM_053974.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus eukaryotic translation initiation factor 4E (Eif4e), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053974.2

ORF Insert Sequence:

ATGGCGACTG TGGAACCGGA AACCACCCCT ACCACTAATC CCCCACCTGC GGAAGAGGAA 
AAAACAGAGT CTAATCAGGA GGTTGCTAAT CCAGAGCACT ATATTAAACA CCCTCTACAG 
AACAGGTGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTT 
CGGTTGATCT CTAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTATACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAGCAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TGCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGACGTGTGT GGAGCTGTTG TCAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC GACTGAATGT GAAAACAGAG ATGCAGTCAC ACACATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCGAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACAAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Eif4e ( XM_008761488.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008759710.1 Rattus norvegicus eukaryotic translation initiation factor 4E (Eif4e), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa12530
Clone ID Related Accession (Same CDS sequence)	XM_008761488.2 , NM_053974.2
Accession Version	XM_008761488.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	eukaryotic translation initiation factor 4E isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008761488.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACTG TGGAACCGGA AACCACCCCT ACCACTAATC CCCCACCTGC GGAAGAGGAA 
AAAACAGAGT CTAATCAGGA GGTTGCTAAT CCAGAGCACT ATATTAAACA CCCTCTACAG 
AACAGGTGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTT 
CGGTTGATCT CTAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTATACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAGCAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TGCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGACGTGTGT GGAGCTGTTG TCAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC GACTGAATGT GAAAACAGAG ATGCAGTCAC ACACATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCGAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACAAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008759710.1
CDS	125..778
Translation	MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Target ORF information:

RefSeq Version	XM_008761488.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus eukaryotic translation initiation factor 4E (Eif4e), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008761488.2

ORF Insert Sequence:

ATGGCGACTG TGGAACCGGA AACCACCCCT ACCACTAATC CCCCACCTGC GGAAGAGGAA 
AAAACAGAGT CTAATCAGGA GGTTGCTAAT CCAGAGCACT ATATTAAACA CCCTCTACAG 
AACAGGTGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTT 
CGGTTGATCT CTAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTATACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAGCAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TGCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGACGTGTGT GGAGCTGTTG TCAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC GACTGAATGT GAAAACAGAG ATGCAGTCAC ACACATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCGAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACAAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Eif4e ( XM_017590592.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017446081.1 Rattus norvegicus eukaryotic translation initiation factor 4E (Eif4e), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa59594
Clone ID Related Accession (Same CDS sequence)	XM_017590592.1
Accession Version	XM_017590592.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	eukaryotic translation initiation factor 4E isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACTG TGGAACCGGA AACCACCCCT ACCACTAATC CCCCACCTGC GGAAGAGGAA 
AAAACAGAGT CTAATCAGGA GGTTGCTAAT CCAGAGCACT ATATTAAACA CCCTCTACAG 
AACAGTCTAT ACAACCATAT CCAGTTGTCT AGTAATTTAA TGCCTGGCTG TGACTACTCA 
CTTTTTAAGG ATGGTATTGA GCCTATGTGG GAAGATGAGA AAAACAAACG GGGAGGACGA 
TGGCTAATTA CATTGAACAA GCAGCAGAGA CGAAGTGACC TCGATCGCTT TTGGCTAGAG 
ACACTGCTGT GCCTTATTGG AGAATCTTTT GATGACTACA GTGATGACGT GTGTGGAGCT 
GTTGTCAATG TTAGAGCTAA AGGTGATAAG ATAGCAATAT GGACGACTGA ATGTGAAAAC 
AGAGATGCAG TCACACACAT AGGGAGGGTA TACAAGGAAA GGTTAGGACT TCCTCCGAAG 
ATAGTGATTG GTTATCAGTC CCACGCAGAC ACAGCTACAA AGAGCGGCTC CACCACTAAA 
AATAGGTTTG TTGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017446081.1
CDS	178..735
Translation	MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNSLYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Target ORF information:

RefSeq Version	XM_017590592.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus eukaryotic translation initiation factor 4E (Eif4e), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017590592.1

ORF Insert Sequence:

ATGGCGACTG TGGAACCGGA AACCACCCCT ACCACTAATC CCCCACCTGC GGAAGAGGAA 
AAAACAGAGT CTAATCAGGA GGTTGCTAAT CCAGAGCACT ATATTAAACA CCCTCTACAG 
AACAGTCTAT ACAACCATAT CCAGTTGTCT AGTAATTTAA TGCCTGGCTG TGACTACTCA 
CTTTTTAAGG ATGGTATTGA GCCTATGTGG GAAGATGAGA AAAACAAACG GGGAGGACGA 
TGGCTAATTA CATTGAACAA GCAGCAGAGA CGAAGTGACC TCGATCGCTT TTGGCTAGAG 
ACACTGCTGT GCCTTATTGG AGAATCTTTT GATGACTACA GTGATGACGT GTGTGGAGCT 
GTTGTCAATG TTAGAGCTAA AGGTGATAAG ATAGCAATAT GGACGACTGA ATGTGAAAAC 
AGAGATGCAG TCACACACAT AGGGAGGGTA TACAAGGAAA GGTTAGGACT TCCTCCGAAG 
ATAGTGATTG GTTATCAGTC CCACGCAGAC ACAGCTACAA AGAGCGGCTC CACCACTAAA 
AATAGGTTTG TTGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis.
Toxicological sciences : an official journal of the Society of Toxicology143(1)81-96(2015 Jan)
Zhou Q,Liu C,Liu W,Zhang H,Zhang R,Liu J,Zhang J,Xu C,Liu L,Huang S,Chen L

Dissociation of eIF4E-binding protein 2 (4E-BP2) from eIF4E independent of Thr37/Thr46 phosphorylation in the ischemic stress response.
PloS one10(3)e0121958(2015)
Ayuso MI,Martinez-Alonso E,Salvador N,Bonova P,Regidor I,Alc?zar A

An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program.
Neuron84(4)723-39(2014 Nov)
Yang G,Smibert CA,Kaplan DR,Miller FD

Requirement of Mammalian target of rapamycin complex 1 downstream effectors in cued fear memory reconsolidation and its persistence.
The Journal of neuroscience : the official journal of the Society for Neuroscience34(27)9034-9(2014 Jul)
Huynh TN,Santini E,Klann E

The scanning mechanism of eukaryotic translation initiation.
Annual review of biochemistry83779-812(2014)
Hinnebusch AG

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Eif4e cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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