Cox7c cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cox7c
Entrez Gene ID	100188937
Full Name	cytochrome c oxidase subunit 7C
Synonyms	Cox7c1
General protein information	Preferred Names cytochrome c oxidase subunit 7C Names cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase polypeptide VIIIA Cytochrome c oxidase polypeptide VIIc cytochrome c oxidase, subunit VIIc
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001134705.1	NP_001128177.1	cytochrome c oxidase subunit 7C, mitochondrial

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LOC100335836	XP_005209785.1
Danio rerio (zebrafish)	cox7c	NP_956289.1
Xenopus tropicalis (tropical clawed frog)	cox7c	NP_001165232.1
Canis lupus familiaris (dog)	LOC609990	XP_852456.2
Gallus gallus (chicken)	COX7C	XP_429181.3
Mus musculus (house mouse)	Cox7c	NP_031775.1
Canis lupus familiaris (dog)	LOC102155410	XP_005633504.1
Rattus norvegicus (Norway rat)	Cox7c	NP_001128177.1
	LOC100428967	XP_002804883.1

Gene Ontology
Bibliography

Related articles in PubMed

Reduced Mitochondrial Activity is Early and Steady in the Entorhinal Cortex but it is Mainly Unmodified in the Frontal Cortex in Alzheimer's Disease.
Armand-Ugon M, Ansoleaga B, Berjaoui S, Ferrer I
Current Alzheimer research14(12)1327-1334(2017)

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.
Zhao X, Le?n IR, Bak S, Mogensen M, Wrzesinski K, H?jlund K, Jensen ON
Molecular & cellular proteomics : MCP10(1)M110.000299(2011 Jan)

Proteomic analysis of the mouse liver mitochondrial inner membrane.
Da Cruz S, Xenarios I, Langridge J, Vilbois F, Parone PA, Martinou JC
The Journal of biological chemistry278(42)41566-71(2003 Oct)

Cytochrome-c oxidase in developing rat heart. Enzymic properties and amino-terminal sequences suggest identity of the fetal heart and the adult liver isoform.
Sch?gger H, Noack H, Halangk W, Brandt U, von Jagow G
European journal of biochemistry230(1)235-41(1995 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cox7c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cox7c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12126	NM_001134705.1 Latest version!	Rattus norvegicus cytochrome c oxidase subunit 7C (Cox7c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cox7c ( NM_001134705.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001128177.1 Rattus norvegicus cytochrome c oxidase subunit 7C (Cox7c), mRNA.

Price & Availability↑

CloneID	ORa12126
Clone ID Related Accession (Same CDS sequence)	NM_001134705.1
Accession Version	NM_001134705.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 192bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome c oxidase subunit 7C, mitochondrial
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI289576.1, BC166894.1 and BQ779631.1. ##Evidence-Data-START## Transcript exon combination :: FQ221226.1, BE126484.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906351, SAMN01906352 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGTTGGGCC AGAGTATCCG GAGGTTCACC ACCTCCGTGG TGCGTCGCAG CCACTATGAG 
GAGGGTCCGG GGAAGAATTT GCCGTTTTCA GTGGAAAACA AGTGGCGGTT ACTGCTTATG 
ATGACCGTGT ACTTTGGATC TGGATTTGCT GCTCCTTTCT TTATAGTAAG GCACCAGCTA 
CTTAAAAAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128177.1
CDS	142..333
Translation	MLGQSIRRFTTSVVRRSHYEEGPGKNLPFSVENKWRLLLMMTVYFGSGFAAPFFIVRHQLLKK

Target ORF information:

RefSeq Version	NM_001134705.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome c oxidase subunit 7C (Cox7c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134705.1

ORF Insert Sequence:

ATGTTGGGCC AGAGTATCCG GAGGTTCACC ACCTCCGTGG TGCGTCGCAG CCACTATGAG 
GAGGGTCCGG GGAAGAATTT GCCGTTTTCA GTGGAAAACA AGTGGCGGTT ACTGCTTATG 
ATGACCGTGT ACTTTGGATC TGGATTTGCT GCTCCTTTCT TTATAGTAAG GCACCAGCTA 
CTTAAAAAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Reduced Mitochondrial Activity is Early and Steady in the Entorhinal Cortex but it is Mainly Unmodified in the Frontal Cortex in Alzheimer's Disease.
Current Alzheimer research14(12)1327-1334(2017)
Armand-Ugon M,Ansoleaga B,Berjaoui S,Ferrer I

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.
Molecular & cellular proteomics : MCP10(1)M110.000299(2011 Jan)
Zhao X,Le?n IR,Bak S,Mogensen M,Wrzesinski K,H?jlund K,Jensen ON

Proteomic analysis of the mouse liver mitochondrial inner membrane.
The Journal of biological chemistry278(42)41566-71(2003 Oct)
Da Cruz S,Xenarios I,Langridge J,Vilbois F,Parone PA,Martinou JC

Cytochrome-c oxidase in developing rat heart. Enzymic properties and amino-terminal sequences suggest identity of the fetal heart and the adult liver isoform.
European journal of biochemistry230(1)235-41(1995 May)
Sch?gger H,Noack H,Halangk W,Brandt U,von Jagow G