Cxcr6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cxcr6
Entrez Gene ID	100124593
Full Name	C-X-C motif chemokine receptor 6
General protein information	Preferred Names C-X-C motif chemokine receptor 6 Names C-X-C chemokine receptor type 6 chemokine (C-X-C motif) receptor 6 chemokine receptor CXCR6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q32

mRNA and Protein(s)

mRNA	Protein	Name
NM_001102587.2	NP_001096057.1	C-X-C chemokine receptor type 6

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CXCR6	NP_001014859.1
Rattus norvegicus (Norway rat)	Cxcr6	NP_001096057.1
Homo sapiens (human)	CXCR6	NP_006555.1
Mus musculus (house mouse)	Cxcr6	NP_109637.3
Xenopus tropicalis (tropical clawed frog)	cxcr6	XP_002933456.1
Pan troglodytes (chimpanzee)	CXCR6	NP_001009051.1
	CXCR6	NP_001040606.1
Canis lupus familiaris (dog)	CXCR6	XP_851891.1

Gene Ontology
Bibliography

Related articles in PubMed

Dysregulated expression of MIG/CXCL9, IP-10/CXCL10 and CXCL16 and their receptors in systemic sclerosis.
Rabquer BJ, Tsou PS, Hou Y, Thirunavukkarasu E, Haines GK 3rd, Impens AJ, Phillips K, Kahaleh B, Seibold JR, Koch AE
Arthritis research & therapy13(1)R18(2011 Feb)

CXCR6 is expressed on T cells in both T helper type 1 (Th1) inflammation and allergen-induced Th2 lung inflammation but is only a weak mediator of chemotaxis.
Latta M, Mohan K, Issekutz TB
Immunology121(4)555-64(2007 Aug)

A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo.
Matloubian M, David A, Engel S, Ryan JE, Cyster JG
Nature immunology1(4)298-304(2000 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cxcr6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cxcr6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa63255	NM_001102587.2 Latest version!	Rattus norvegicus C-X-C motif chemokine receptor 6 (Cxcr6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cxcr6 ( NM_001102587.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001096057.1 Rattus norvegicus C-X-C motif chemokine receptor 6 (Cxcr6), mRNA.

Price & Availability↑

CloneID	ORa63255
Clone ID Related Accession (Same CDS sequence)	NM_001102587.2
Accession Version	NM_001102587.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-02
Organism	Rattus norvegicus(Norway rat)
Product	C-X-C chemokine receptor type 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DQ132631.1 and AABR07071820.1. On Mar 9, 2017 this sequence version replaced NM_001102587.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. COMPLETENESS: complete on the 3' end.

ATGGATGATG GGCATCAAGA GAAAGATCTG GACGATGACG TCTACGGGGG AGATCCCTGG 
CTCTTCAACA ACTCCAGTGG TAACAGCCAG GAACACAAAC GCTTCCTAAA GTTCAAGGAG 
GTTTTTCTGC CCTGCATGTA TCTGGTAGTG TTTGTCCTTG GACTGCTAGG GAACTCCCTG 
GTTCTGATTA TATACATTTT CTACCAGAGG CTGAGGAGTC TGACAGACGT GTTCCTGCTG 
AACTTGCCCC TGGCTGACCT GGTGTTTGTC TGTACTCTGC CCTTTTGGGC CTACGCAGGC 
ACCTATGAGT GGGTCTTTGG CACAGCCATG TGCAAAACTC TTCGAAGCAT GTATGCAATG 
AACTTCTACG TGTCCATGCT CACTCTCACC TGCATCACGG TGGATCGTTT CGTTGTAGTG 
GTCCAGGCTA CCAAGGCCTT CAACAGGCAG GCTAAGTGGA AGATCTGGGG CCAAGTCACT 
TGCTTGCTCA TCTGGGTAGT CTCCCTGCTG GTTTCTTTGC CACAGATCAT CTACAGCAGA 
GTTGGACATA TTGACAGGCT TATCTGTCAG TTCCACAACG AGGCGATATC GACTGTGGTT 
CTTGTTCTAC AGATGACTCT GGGGTTCTTC CTGCCATTGC TCACTATGAT TCTGTGCTAC 
TCAGGCATTA TCAAGACCTT GCTTCACGCT CGAAACTTCC AGAAGCACAA ATCTCTAAAG 
ATCATCTTCC TTGTAGTGGC TACGTTCCTG CTGACCCAGA CACCCTTCAA CATTGCCATG 
TTAATCCAGT GGATAAGTTG GGAATACAGT ACCATAACCA GCTTTCAGTA TGTCGTCTTA 
GTGACAGAGG CGATAGCATA CCTTCGGGCC TGCCTTAACC CTGTACTCTA TGCCTTTGTT 
GGCTTAAAGT TCCGGAAGAA CCTCTGGAAA CTTATGAAGG ACATCAGCTG CCTCTCTCGT 
CTGGGAGTCT CAAGTCAGTG GAAGTCTTCT GAGGACAATT CCAAGACTTG TTCTGCCTCC 
CACAATGCAG AGACCACCAG TATGTTCCAA TTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001096057.1
CDS	1..1056
Translation	MDDGHQEKDLDDDVYGGDPWLFNNSSGNSQEHKRFLKFKEVFLPCMYLVVFVLGLLGNSLVLIIYIFYQRLRSLTDVFLLNLPLADLVFVCTLPFWAYAGTYEWVFGTAMCKTLRSMYAMNFYVSMLTLTCITVDRFVVVVQATKAFNRQAKWKIWGQVTCLLIWVVSLLVSLPQIIYSRVGHIDRLICQFHNEAISTVVLVLQMTLGFFLPLLTMILCYSGIIKTLLHARNFQKHKSLKIIFLVVATFLLTQTPFNIAMLIQWISWEYSTITSFQYVVLVTEAIAYLRACLNPVLYAFVGLKFRKNLWKLMKDISCLSRLGVSSQWKSSEDNSKTCSASHNAETTSMFQL

Target ORF information:

RefSeq Version	NM_001102587.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus C-X-C motif chemokine receptor 6 (Cxcr6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001102587.2

ORF Insert Sequence:

ATGGATGATG GGCATCAAGA GAAAGATCTG GACGATGACG TCTACGGGGG AGATCCCTGG 
CTCTTCAACA ACTCCAGTGG TAACAGCCAG GAACACAAAC GCTTCCTAAA GTTCAAGGAG 
GTTTTTCTGC CCTGCATGTA TCTGGTAGTG TTTGTCCTTG GACTGCTAGG GAACTCCCTG 
GTTCTGATTA TATACATTTT CTACCAGAGG CTGAGGAGTC TGACAGACGT GTTCCTGCTG 
AACTTGCCCC TGGCTGACCT GGTGTTTGTC TGTACTCTGC CCTTTTGGGC CTACGCAGGC 
ACCTATGAGT GGGTCTTTGG CACAGCCATG TGCAAAACTC TTCGAAGCAT GTATGCAATG 
AACTTCTACG TGTCCATGCT CACTCTCACC TGCATCACGG TGGATCGTTT CGTTGTAGTG 
GTCCAGGCTA CCAAGGCCTT CAACAGGCAG GCTAAGTGGA AGATCTGGGG CCAAGTCACT 
TGCTTGCTCA TCTGGGTAGT CTCCCTGCTG GTTTCTTTGC CACAGATCAT CTACAGCAGA 
GTTGGACATA TTGACAGGCT TATCTGTCAG TTCCACAACG AGGCGATATC GACTGTGGTT 
CTTGTTCTAC AGATGACTCT GGGGTTCTTC CTGCCATTGC TCACTATGAT TCTGTGCTAC 
TCAGGCATTA TCAAGACCTT GCTTCACGCT CGAAACTTCC AGAAGCACAA ATCTCTAAAG 
ATCATCTTCC TTGTAGTGGC TACGTTCCTG CTGACCCAGA CACCCTTCAA CATTGCCATG 
TTAATCCAGT GGATAAGTTG GGAATACAGT ACCATAACCA GCTTTCAGTA TGTCGTCTTA 
GTGACAGAGG CGATAGCATA CCTTCGGGCC TGCCTTAACC CTGTACTCTA TGCCTTTGTT 
GGCTTAAAGT TCCGGAAGAA CCTCTGGAAA CTTATGAAGG ACATCAGCTG CCTCTCTCGT 
CTGGGAGTCT CAAGTCAGTG GAAGTCTTCT GAGGACAATT CCAAGACTTG TTCTGCCTCC 
CACAATGCAG AGACCACCAG TATGTTCCAA TTGTAA