MYOM2 cDNA ORF clone, Pterocles gutturalis(yellow-throated sandgrouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	MYOM2
Entrez Gene ID	104465649
Full Name	myomesin 2
Gene Type	protein-coding
Organism	Pterocles gutturalis(yellow-throated sandgrouse)

mRNA and Protein(s)

mRNA	Protein	Name
XM_010078776.1	XP_010077078.1	myomesin-2

Pathways from BioSystems
Gene Ontology

The following MYOM2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MYOM2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OPt36772	XM_010078776.1 Latest version!	Pterocles gutturalis myomesin 2 (MYOM2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$713.30 $1019.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MYOM2 ( XM_010078776.1 ) cDNA ORF clone, Pterocles gutturalis(yellow-throated sandgrouse) -> XP_010077078.1 Pterocles gutturalis myomesin 2 (MYOM2), mRNA.

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CloneID	OPt36772
Clone ID Related Accession (Same CDS sequence)	XM_010078776.1
Accession Version	XM_010078776.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2014-11-05
Organism	Pterocles gutturalis(yellow-throated sandgrouse)
Product	myomesin-2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_010125908.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Pterocles gutturalis Annotation Release 100 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END##

ATGGATCAGC ACCTCATCAG CAGTGGCAGC ATGGCTCCCC CAGCATGTAC TGTGACAGAT 
GCAAATGTGC ACCGTCCTCC TGGAGGGTCT GGCTCATCTG TTTTCCTCCT TCCCCTTTTC 
AGAGCTGATT TTGATGATTC TGCTACCTAC TCAGCAGTTG CAACAAATGT CCATGGGCAG 
GCATCCACTA ATTGTGCTGT GATTGTGCGA AGGTTCAGAG AGGATGAAGA GCCTCACCCA 
GCTGGGATAA TGCCCTTCCA CTTGCCCCTG TCATATGATG TTTGCTTCAC CCACATTGAT 
GTCCAGTTTC TGGAGAAGTT TGGAGTCACC TTTGGAACTG AAGGTGAAAC ACTGACCCTG 
AAGTGTTCTA TGCTGATCAC ACCAGACCTG AAAAGACTAC GACCTCGTGC TGAGTGGTAT 
AGAGATGACG TGCTGATAAA GGAATCCCAG TGGACAAAGC TGTATTTTGG AGAAGGCCAG 
GCAGCTCTGT CCTTTACCCA TCTGAACAAA GATGATGAAG GTTTATACAC CCTGCGCATG 
GTTACGAAAG GTGGAGTGAG TGAATACAGT GCATACCTGT TTGTCAGAGA TGCTGATGCA 
TTGATTGCGG GAGCACCAGG GGCACCGATG GATGTTAAAT GCCATGATGC TAACAGAGAC 
TATGTTATTG TTACCTGGAA ACCACCAAAC ACAACCAGTG AGAGCCCAGT CATTGGATAT 
TTTGTTGACA AGTGTGAAGT AGGTTTGGAA AACTGGGTCC AGTGCAATGA TGCTCCTGTA 
AAAATCTGCA AGTATCCTGT GACTGGTCTT TACGAGGGAC GGTCTTACAT ATTCCGTGTG 
AGAGCAGTGA ACAGTGCTGG CATTAGCAGG CCTTCTCGAG TCTCTGAACC AGTTGCAGCT 
CTTGACCCGG TTGACCTGGA GAGAACACAA AGTATTCATG TGGATGAAGG GCGAAAGATT 
GTGATCCGTA AGGATGACCT TGAAGGTGAT ATTCAGATTC CAGGCCCTCC TACCAATGTA 
CATGCTTCAG AAATCAGCAG AACGTATGTT GTACTCAGCT GGGATCCACC TGTTCCCCGT 
GGCAGGGAGC CGTTGACGTA TTTCATTGAG AAGTCTATGG TTGGCAGTGG AAGCTGGCAA 
AGAGTCAATG CGCAGGTTGC AGTAAAATCT CCTCGCTATG CAGTATTTGA CCTTGCAGAA 
GGAAAACCAT ATGTTTTCCG AGTCTTGTCA GCAAACAAGC ACGGCATCAG TGATCCATCT 
GAAATCACAA GCCCTATTCA ACCACAAGAT ACCATTGTTG TACCATCTGC ACCTGGTCGG 
GTGGTGGCCA CAAGAAATAC AAAAACATCA GTTGTAGTTC AATGGGATAA GCCAAAACAT 
GAAGAAGATT TATATGGCTA CTACATTGAC TATTCTGTGG TGGGATCAAA TCACTGGGAA 
CCTAGTAACC ATAAACCCAT TAAATATAAC AGGTTTGTTG TTCATGGTTT GGAAACTGGA 
GAGCAGTACA TCTTCCGTGT GAAAGCTGTG AATGCTGTAG GATTCAGTGA AAACTCACAG 
GAGTCAGAAG CTATAACAGT ACAGGCAGCC CTTACTTGTC CATCATATCC TCATGGTATC 
ACACTTCTGA ACTGTGATGG TCATTCAATG ACCCTTGGTT GGAAAGCACC AAGATACAGT 
GGAGGTTCAC CAATCCTTGG TTATTATTTG GATAAACGGG AAGCTAACCA TCGAAACTGG 
CATGAAGTAA ATTCTTCCCT TATCACCCGG ACAATTTATA CGGTGGAGGA TTTAACAGAA 
GATGCCTTCT ATGAATTCAA AGTTGCTGCT GCAAATCTGG TTGGAATAGG TCAACCTTCA 
GATCCCAGTG AGCATTTTAA GTGTAAAGCC TGGACTATGC CAGAACCTGG TCCTGCCTAT 
GATCTCACGA TTTGTGAAGT TAGAAATACA TCACTGGTTC TTCTGTGGAA AGCTCCCGTA 
TATGAAGGCA AAAGCCCTAT TACTGGGTAT TTAGTGGACT ATAAGGAAGT AGATACAGAA 
GACTGGATCA CTGCTAATGA AAAACCTACT TCAAAGCGCT ATTTGAAGGT CACTGATTTG 
CATGAAGGTC ATACCTATGT TTTCAAAGTT CGTGCAGTGA ATGATGCTGG GGTAGGCAAG 
TCATCTGAGA TATCTGAACC AGTGCTTGTT GAGGCACGGC CAGGAACAAA AGAAATCTTT 
TCAGGTGTGG ATGACGAGGG TAATATATAC CTGGCTTTTG AGTGCAAAGA AGCTACAGAT 
GCATCTCATT TTGCATGGGG TAAATCGTAT GAGGAGATTG AGGATTCTGA TAAGTTTAAG 
ATTGAAACAG AAGGAAATCA TTCTAAGCTG TACTTCAAAA ATCCTGATAA ATCAGACTTG 
GGAACCTATT CTATCGCAGT TAGTGACACA GACGGGGTTT CATCCAGCTT CATTATGGAT 
GATGAAGAGC TTGAACGTTT GATGGCATTA AGCAATGAAA TAAAGAATCC AACAATACCT 
CTGAAATCAG AATTAGCTTA TGAGGTTCTT GAGAAAGGAG AAGTTCGTTT CTGGATTCAG 
GCCGAAAGCT TATCACCAGA TTCTACCTTC AGATTCGTTA TTAATGATAA AGAAGTTGAA 
AACAGCGATA GGCATAAAAT AAATTGTGAC CGTTCAAATG GCATTATAGA AATGGTGATG 
GACCGGTTTA CAATTGACAA TGAAGGTACC TACACAGTAC AGATTCAAGA TGGAAAGGCC 
AAGAACCAGT CTTCATTAGT TCTCATTGGA GATGCATTCA AGGCAGTATT GGCTGAGTCT 
GAGCTCCAGC GAAAGGAATT TCTCAGGAAG CAAGGTCCTC ACTTCTCAGA GTTTTTGTAT 
TGGAAAGTTA CAGATGAATG TGAAGTTTTA CTTGCTTGTA AGGTTGCGAA CACAAAGAAG 
GAGACTGTTT TCAAGTGGTA TAGGGATGGT TCTGGGATTG ATGTTGATGA GGTGCCTGAT 
CTGCAGAAGG GAGAATGTCA CCTCACTATT CCCAAGCTTT CTCGCAAAGA TGAAGGAGTT 
TATAAGGCAA CACTATCAGA TGATAGAGGT CATGATGTAT CTACTCTTGA ATTATCAGGA 
AAAGTGTATG ATGATATAAT TCTGGCACTG AGTGGAGTCA GTGGTAAGTC AGCCTCTCAA 
CTGAAGATCC TTTGCACTGC GGAAGGAATA AGGCTCCAGT GTTTCTTGAA GTACTACAAT 
GAAGAAATGA AAGTCAACTG GTCTCATAGG GAATCTAAGA TTTCTTCTGG TGAAAAGATG 
AAGATTGGAG GTGGAGAGGA TGTTGCCTGG CTGCAGATAA GTGAACCCAC TGAAAAGGAT 
AAGGGGAACT ACACCTTTGA AATCTTTGGC CCCAAGGAAT CCTACAAACG CGTACTTGAT 
CTGTCTGGGC AAGCTTTTGA TGATGCATAT GCAGAATTTC AGCGACTCAA GGCAGCAGCT 
TTTGCTGAGA AAAATCGTGG TAAAGTCGTT GGTGGTTTGC CAGATGTTGT TACTATAATG 
GATGGAAAGA CGCTGAATCT GACCTGTACT GTGTTTGGAA ATCCTGACCC TGAAGTGGTT 
TGGTTCAAGA ACGACAAGGT CTTTGAACTT AATGAGCACT ATGCGTTTTC ACTGGAACAA 
GGGAAATATG CCAGTTTAAC AATCAAGGGA GTGACCTCAG ATGACTCGGG CAAATATAGC 
ATCCATGTCA AGAACAAGTA TGGCGGGGAA ACTGTGGATG TCACTGTAAG TGTGTACAGA 
CATGGTGAAA AAATGCCTGA AGTTAAGCCT GGCCAGCTTG CTAAACCCAG GCCAATACCA 
CCATCAGAAG AAGTCCTCAA ACCTGGGGGT GAGGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010077078.1
CDS	1..3879
Translation	MDQHLISSGSMAPPACTVTDANVHRPPGGSGSSVFLLPLFRADFDDSATYSAVATNVHGQASTNCAVIVRRFREDEEPHPAGIMPFHLPLSYDVCFTHIDVQFLEKFGVTFGTEGETLTLKCSMLITPDLKRLRPRAEWYRDDVLIKESQWTKLYFGEGQAALSFTHLNKDDEGLYTLRMVTKGGVSEYSAYLFVRDADALIAGAPGAPMDVKCHDANRDYVIVTWKPPNTTSESPVIGYFVDKCEVGLENWVQCNDAPVKICKYPVTGLYEGRSYIFRVRAVNSAGISRPSRVSEPVAALDPVDLERTQSIHVDEGRKIVIRKDDLEGDIQIPGPPTNVHASEISRTYVVLSWDPPVPRGREPLTYFIEKSMVGSGSWQRVNAQVAVKSPRYAVFDLAEGKPYVFRVLSANKHGISDPSEITSPIQPQDTIVVPSAPGRVVATRNTKTSVVVQWDKPKHEEDLYGYYIDYSVVGSNHWEPSNHKPIKYNRFVVHGLETGEQYIFRVKAVNAVGFSENSQESEAITVQAALTCPSYPHGITLLNCDGHSMTLGWKAPRYSGGSPILGYYLDKREANHRNWHEVNSSLITRTIYTVEDLTEDAFYEFKVAAANLVGIGQPSDPSEHFKCKAWTMPEPGPAYDLTICEVRNTSLVLLWKAPVYEGKSPITGYLVDYKEVDTEDWITANEKPTSKRYLKVTDLHEGHTYVFKVRAVNDAGVGKSSEISEPVLVEARPGTKEIFSGVDDEGNIYLAFECKEATDASHFAWGKSYEEIEDSDKFKIETEGNHSKLYFKNPDKSDLGTYSIAVSDTDGVSSSFIMDDEELERLMALSNEIKNPTIPLKSELAYEVLEKGEVRFWIQAESLSPDSTFRFVINDKEVENSDRHKINCDRSNGIIEMVMDRFTIDNEGTYTVQIQDGKAKNQSSLVLIGDAFKAVLAESELQRKEFLRKQGPHFSEFLYWKVTDECEVLLACKVANTKKETVFKWYRDGSGIDVDEVPDLQKGECHLTIPKLSRKDEGVYKATLSDDRGHDVSTLELSGKVYDDIILALSGVSGKSASQLKILCTAEGIRLQCFLKYYNEEMKVNWSHRESKISSGEKMKIGGGEDVAWLQISEPTEKDKGNYTFEIFGPKESYKRVLDLSGQAFDDAYAEFQRLKAAAFAEKNRGKVVGGLPDVVTIMDGKTLNLTCTVFGNPDPEVVWFKNDKVFELNEHYAFSLEQGKYASLTIKGVTSDDSGKYSIHVKNKYGGETVDVTVSVYRHGEKMPEVKPGQLAKPRPIPPSEEVLKPGGEA

Target ORF information:

RefSeq Version	XM_010078776.1
Organism	Pterocles gutturalis(yellow-throated sandgrouse)
Definition	Pterocles gutturalis myomesin 2 (MYOM2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010078776.1

ORF Insert Sequence:

ATGGATCAGC ACCTCATCAG CAGTGGCAGC ATGGCTCCCC CAGCATGTAC TGTGACAGAT 
GCAAATGTGC ACCGTCCTCC TGGAGGGTCT GGCTCATCTG TTTTCCTCCT TCCCCTTTTC 
AGAGCTGATT TTGATGATTC TGCTACCTAC TCAGCAGTTG CAACAAATGT CCATGGGCAG 
GCATCCACTA ATTGTGCTGT GATTGTGCGA AGGTTCAGAG AGGATGAAGA GCCTCACCCA 
GCTGGGATAA TGCCCTTCCA CTTGCCCCTG TCATATGATG TTTGCTTCAC CCACATTGAT 
GTCCAGTTTC TGGAGAAGTT TGGAGTCACC TTTGGAACTG AAGGTGAAAC ACTGACCCTG 
AAGTGTTCTA TGCTGATCAC ACCAGACCTG AAAAGACTAC GACCTCGTGC TGAGTGGTAT 
AGAGATGACG TGCTGATAAA GGAATCCCAG TGGACAAAGC TGTATTTTGG AGAAGGCCAG 
GCAGCTCTGT CCTTTACCCA TCTGAACAAA GATGATGAAG GTTTATACAC CCTGCGCATG 
GTTACGAAAG GTGGAGTGAG TGAATACAGT GCATACCTGT TTGTCAGAGA TGCTGATGCA 
TTGATTGCGG GAGCACCAGG GGCACCGATG GATGTTAAAT GCCATGATGC TAACAGAGAC 
TATGTTATTG TTACCTGGAA ACCACCAAAC ACAACCAGTG AGAGCCCAGT CATTGGATAT 
TTTGTTGACA AGTGTGAAGT AGGTTTGGAA AACTGGGTCC AGTGCAATGA TGCTCCTGTA 
AAAATCTGCA AGTATCCTGT GACTGGTCTT TACGAGGGAC GGTCTTACAT ATTCCGTGTG 
AGAGCAGTGA ACAGTGCTGG CATTAGCAGG CCTTCTCGAG TCTCTGAACC AGTTGCAGCT 
CTTGACCCGG TTGACCTGGA GAGAACACAA AGTATTCATG TGGATGAAGG GCGAAAGATT 
GTGATCCGTA AGGATGACCT TGAAGGTGAT ATTCAGATTC CAGGCCCTCC TACCAATGTA 
CATGCTTCAG AAATCAGCAG AACGTATGTT GTACTCAGCT GGGATCCACC TGTTCCCCGT 
GGCAGGGAGC CGTTGACGTA TTTCATTGAG AAGTCTATGG TTGGCAGTGG AAGCTGGCAA 
AGAGTCAATG CGCAGGTTGC AGTAAAATCT CCTCGCTATG CAGTATTTGA CCTTGCAGAA 
GGAAAACCAT ATGTTTTCCG AGTCTTGTCA GCAAACAAGC ACGGCATCAG TGATCCATCT 
GAAATCACAA GCCCTATTCA ACCACAAGAT ACCATTGTTG TACCATCTGC ACCTGGTCGG 
GTGGTGGCCA CAAGAAATAC AAAAACATCA GTTGTAGTTC AATGGGATAA GCCAAAACAT 
GAAGAAGATT TATATGGCTA CTACATTGAC TATTCTGTGG TGGGATCAAA TCACTGGGAA 
CCTAGTAACC ATAAACCCAT TAAATATAAC AGGTTTGTTG TTCATGGTTT GGAAACTGGA 
GAGCAGTACA TCTTCCGTGT GAAAGCTGTG AATGCTGTAG GATTCAGTGA AAACTCACAG 
GAGTCAGAAG CTATAACAGT ACAGGCAGCC CTTACTTGTC CATCATATCC TCATGGTATC 
ACACTTCTGA ACTGTGATGG TCATTCAATG ACCCTTGGTT GGAAAGCACC AAGATACAGT 
GGAGGTTCAC CAATCCTTGG TTATTATTTG GATAAACGGG AAGCTAACCA TCGAAACTGG 
CATGAAGTAA ATTCTTCCCT TATCACCCGG ACAATTTATA CGGTGGAGGA TTTAACAGAA 
GATGCCTTCT ATGAATTCAA AGTTGCTGCT GCAAATCTGG TTGGAATAGG TCAACCTTCA 
GATCCCAGTG AGCATTTTAA GTGTAAAGCC TGGACTATGC CAGAACCTGG TCCTGCCTAT 
GATCTCACGA TTTGTGAAGT TAGAAATACA TCACTGGTTC TTCTGTGGAA AGCTCCCGTA 
TATGAAGGCA AAAGCCCTAT TACTGGGTAT TTAGTGGACT ATAAGGAAGT AGATACAGAA 
GACTGGATCA CTGCTAATGA AAAACCTACT TCAAAGCGCT ATTTGAAGGT CACTGATTTG 
CATGAAGGTC ATACCTATGT TTTCAAAGTT CGTGCAGTGA ATGATGCTGG GGTAGGCAAG 
TCATCTGAGA TATCTGAACC AGTGCTTGTT GAGGCACGGC CAGGAACAAA AGAAATCTTT 
TCAGGTGTGG ATGACGAGGG TAATATATAC CTGGCTTTTG AGTGCAAAGA AGCTACAGAT 
GCATCTCATT TTGCATGGGG TAAATCGTAT GAGGAGATTG AGGATTCTGA TAAGTTTAAG 
ATTGAAACAG AAGGAAATCA TTCTAAGCTG TACTTCAAAA ATCCTGATAA ATCAGACTTG 
GGAACCTATT CTATCGCAGT TAGTGACACA GACGGGGTTT CATCCAGCTT CATTATGGAT 
GATGAAGAGC TTGAACGTTT GATGGCATTA AGCAATGAAA TAAAGAATCC AACAATACCT 
CTGAAATCAG AATTAGCTTA TGAGGTTCTT GAGAAAGGAG AAGTTCGTTT CTGGATTCAG 
GCCGAAAGCT TATCACCAGA TTCTACCTTC AGATTCGTTA TTAATGATAA AGAAGTTGAA 
AACAGCGATA GGCATAAAAT AAATTGTGAC CGTTCAAATG GCATTATAGA AATGGTGATG 
GACCGGTTTA CAATTGACAA TGAAGGTACC TACACAGTAC AGATTCAAGA TGGAAAGGCC 
AAGAACCAGT CTTCATTAGT TCTCATTGGA GATGCATTCA AGGCAGTATT GGCTGAGTCT 
GAGCTCCAGC GAAAGGAATT TCTCAGGAAG CAAGGTCCTC ACTTCTCAGA GTTTTTGTAT 
TGGAAAGTTA CAGATGAATG TGAAGTTTTA CTTGCTTGTA AGGTTGCGAA CACAAAGAAG 
GAGACTGTTT TCAAGTGGTA TAGGGATGGT TCTGGGATTG ATGTTGATGA GGTGCCTGAT 
CTGCAGAAGG GAGAATGTCA CCTCACTATT CCCAAGCTTT CTCGCAAAGA TGAAGGAGTT 
TATAAGGCAA CACTATCAGA TGATAGAGGT CATGATGTAT CTACTCTTGA ATTATCAGGA 
AAAGTGTATG ATGATATAAT TCTGGCACTG AGTGGAGTCA GTGGTAAGTC AGCCTCTCAA 
CTGAAGATCC TTTGCACTGC GGAAGGAATA AGGCTCCAGT GTTTCTTGAA GTACTACAAT 
GAAGAAATGA AAGTCAACTG GTCTCATAGG GAATCTAAGA TTTCTTCTGG TGAAAAGATG 
AAGATTGGAG GTGGAGAGGA TGTTGCCTGG CTGCAGATAA GTGAACCCAC TGAAAAGGAT 
AAGGGGAACT ACACCTTTGA AATCTTTGGC CCCAAGGAAT CCTACAAACG CGTACTTGAT 
CTGTCTGGGC AAGCTTTTGA TGATGCATAT GCAGAATTTC AGCGACTCAA GGCAGCAGCT 
TTTGCTGAGA AAAATCGTGG TAAAGTCGTT GGTGGTTTGC CAGATGTTGT TACTATAATG 
GATGGAAAGA CGCTGAATCT GACCTGTACT GTGTTTGGAA ATCCTGACCC TGAAGTGGTT 
TGGTTCAAGA ACGACAAGGT CTTTGAACTT AATGAGCACT ATGCGTTTTC ACTGGAACAA 
GGGAAATATG CCAGTTTAAC AATCAAGGGA GTGACCTCAG ATGACTCGGG CAAATATAGC 
ATCCATGTCA AGAACAAGTA TGGCGGGGAA ACTGTGGATG TCACTGTAAG TGTGTACAGA 
CATGGTGAAA AAATGCCTGA AGTTAAGCCT GGCCAGCTTG CTAAACCCAG GCCAATACCA 
CCATCAGAAG AAGTCCTCAA ACCTGGGGGT GAGGCATAA