IL2 cDNA ORF clone, Oryctolagus cuniculus(rabbit)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL2
Entrez Gene ID	100302458
Full Name	interleukin 2
Synonyms	TCGF
Gene Type	protein-coding
Organism	Oryctolagus cuniculus(rabbit)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001163180.1	NP_001156652.1	interleukin-2 isoform 1 precursor
NM_001171099.1	NP_001164570.1	interleukin-2 isoform 2 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

[Role of interleukin 2 on apoptosis of lens epithelium cells in intraocular non-infective inflammation induced by iron].
Li XM, Wang W
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology43(10)902-5(2007 Oct)

The complete cDNA sequences of IL-2, IL-4, IL-6 AND IL-10 from the European rabbit (Oryctolagus cuniculus).
Perkins HD, van Leeuwen BH, Hardy CM, Kerr PJ
Cytokine12(6)555-65(2000 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IL-2 activates the STAT3 pathway, protects the lens epithelium cells and reduce the damage caused by inflammation reactions.
Title: [Role of interleukin 2 on apoptosis of lens epithelium cells in intraocular non-infective inflammation induced by iron].

The following IL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OOb00215	NM_001163180.1 Latest version!	Oryctolagus cuniculus interleukin 2 (IL2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OOb00250	NM_001171099.1 Latest version!	Oryctolagus cuniculus interleukin 2 (IL2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL2 ( NM_001163180.1 ) cDNA ORF clone, Oryctolagus cuniculus(rabbit) -> NP_001156652.1 Oryctolagus cuniculus interleukin 2 (IL2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OOb00215
Clone ID Related Accession (Same CDS sequence)	NM_001163180.1
Accession Version	NM_001163180.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Oryctolagus cuniculus(rabbit)
Product	interleukin-2 isoform 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF068057.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AF068057.1, EF586071.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00013641 [ECO:0000348] ##Evidence-Data-END##

ATGTACAAAG TACAACTCTT GTCTTGCATT GCACTAACTC TTGCACTCCT TACAAGCAGT 
GCACCTACTT CAAGTTCTAC AAAGGAAACA CAGGAACAAC TGGATCAGCT ACTGCTGGAT 
TTACAGGTGC TTTTGAAAGG AGTTAATGAT TATAAGAATT CCAAACTTTC CAGGATGCTC 
ACATTCAAAT TTTATATGCC CAAGAAGGTC ACAGAATTGA AACATCTTCA GTGTCTAGAA 
GAAGAACTCA AACCTCTGGA GGAAGTGCTT AACTTAGCTC AAGGCAAAAA CTCTCATGGG 
GGAAATACCA GAGAATCAAT CAGCAATATT AATGTAACAG TTCTGAAACT AAAGGGATCT 
GAAACATTCA TGTGTGAATA CGATGAGACA GTTACCATTG TAGAATTTCT GAACAGATGG 
ATCACCTTTT GTCAAAGCAT CATCTCAGCA TCGAGTTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001156652.1
CDS	48..509
Translation	MYKVQLLSCIALTLALLTSSAPTSSSTKETQEQLDQLLLDLQVLLKGVNDYKNSKLSRMLTFKFYMPKKVTELKHLQCLEEELKPLEEVLNLAQGKNSHGGNTRESISNINVTVLKLKGSETFMCEYDETVTIVEFLNRWITFCQSIISASSS

Target ORF information:

RefSeq Version	NM_001163180.1
Organism	Oryctolagus cuniculus(rabbit)
Definition	Oryctolagus cuniculus interleukin 2 (IL2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001163180.1

ORF Insert Sequence:

ATGTACAAAG TACAACTCTT GTCTTGCATT GCACTAACTC TTGCACTCCT TACAAGCAGT 
GCACCTACTT CAAGTTCTAC AAAGGAAACA CAGGAACAAC TGGATCAGCT ACTGCTGGAT 
TTACAGGTGC TTTTGAAAGG AGTTAATGAT TATAAGAATT CCAAACTTTC CAGGATGCTC 
ACATTCAAAT TTTATATGCC CAAGAAGGTC ACAGAATTGA AACATCTTCA GTGTCTAGAA 
GAAGAACTCA AACCTCTGGA GGAAGTGCTT AACTTAGCTC AAGGCAAAAA CTCTCATGGG 
GGAAATACCA GAGAATCAAT CAGCAATATT AATGTAACAG TTCTGAAACT AAAGGGATCT 
GAAACATTCA TGTGTGAATA CGATGAGACA GTTACCATTG TAGAATTTCT GAACAGATGG 
ATCACCTTTT GTCAAAGCAT CATCTCAGCA TCGAGTTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL2 ( NM_001171099.1 ) cDNA ORF clone, Oryctolagus cuniculus(rabbit) -> NP_001164570.1 Oryctolagus cuniculus interleukin 2 (IL2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OOb00250
Clone ID Related Accession (Same CDS sequence)	NM_001171099.1
Accession Version	NM_001171099.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Oryctolagus cuniculus(rabbit)
Product	interleukin-2 isoform 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF169168.1. Transcript Variant: This variant (2) lacks an exon in the coding region compared to variant 1. The encoded protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AF169168.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00013641, SAMN00013655 [ECO:0000350] ##Evidence-Data-END##

ATGTACAAAG TACAACTCTT GTCTTGCATT GCACTAACTC TTGCACTCCT TACAAGCAGT 
GCACCTACTT CAAGTTCTAC AAAGGAAACA CAGGAACAAC TGGATCAGCT ACTGCTGGAT 
TTACAGGTGC TTTTGAAAGG AGTTAATGTC ACAGAATTGA AACATCTTCA GTGTCTAGAA 
GAAGAACTCA AACCTCTGGA GGAAGTGCTT AACTTAGCTC AAGGCAAAAA CTCTCATGGG 
GGAAATACCA GAGAATCAAT CAGCAATATT AATGTAACAG TTCTGAAACT AAAGGGATCT 
GAAACATTCA TGTGTGAATA CGATGAGACA GTTACCATTG TAGAATTTCT GAACAGATGG 
ATCACCTTTT GTCAAAGCAT CATCTCAGCA TCGAGTTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001164570.1
CDS	1..402
Translation	MYKVQLLSCIALTLALLTSSAPTSSSTKETQEQLDQLLLDLQVLLKGVNVTELKHLQCLEEELKPLEEVLNLAQGKNSHGGNTRESISNINVTVLKLKGSETFMCEYDETVTIVEFLNRWITFCQSIISASSS

Target ORF information:

RefSeq Version	NM_001171099.1
Organism	Oryctolagus cuniculus(rabbit)
Definition	Oryctolagus cuniculus interleukin 2 (IL2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001171099.1

ORF Insert Sequence:

ATGTACAAAG TACAACTCTT GTCTTGCATT GCACTAACTC TTGCACTCCT TACAAGCAGT 
GCACCTACTT CAAGTTCTAC AAAGGAAACA CAGGAACAAC TGGATCAGCT ACTGCTGGAT 
TTACAGGTGC TTTTGAAAGG AGTTAATGTC ACAGAATTGA AACATCTTCA GTGTCTAGAA 
GAAGAACTCA AACCTCTGGA GGAAGTGCTT AACTTAGCTC AAGGCAAAAA CTCTCATGGG 
GGAAATACCA GAGAATCAAT CAGCAATATT AATGTAACAG TTCTGAAACT AAAGGGATCT 
GAAACATTCA TGTGTGAATA CGATGAGACA GTTACCATTG TAGAATTTCT GAACAGATGG 
ATCACCTTTT GTCAAAGCAT CATCTCAGCA TCGAGTTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

[Role of interleukin 2 on apoptosis of lens epithelium cells in intraocular non-infective inflammation induced by iron].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology43(10)902-5(2007 Oct)
Li XM,Wang W

The complete cDNA sequences of IL-2, IL-4, IL-6 AND IL-10 from the European rabbit (Oryctolagus cuniculus).
Cytokine12(6)555-65(2000 Jun)
Perkins HD,van Leeuwen BH,Hardy CM,Kerr PJ