P4HTM cDNA ORF clone, Mus musculus(House mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	P4HTM
Entrez Gene ID	74443
Full Name	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
Synonyms	4933406E20Rik,AI853847,BB128974,HIF-PH4,HPH-4,P4H-TM,Ph-4
General protein information	Preferred Names prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) Names transmembrane prolyl 4-hydroxylase HIF-prolyl hydroxylase 4 hypoxia-inducible factor prolyl hydroxylase 4
Gene Type	protein-coding
Organism	Mus musculus(House mouse)
Genome	Chromosome: 9 Map Location: 9\|9 F2

mRNA and Protein(s)

mRNA	Protein	Name
NM_028944.4	NP_083220.3	transmembrane prolyl 4-hydroxylase isoform 1
NM_001357465.1	NP_001344394.1	transmembrane prolyl 4-hydroxylase isoform 2
XM_011242914.2	XP_011241216.1	transmembrane prolyl 4-hydroxylase isoform X1
XM_011242914.1	XP_011241216.1	transmembrane prolyl 4-hydroxylase isoform X1
NM_028944.3	NP_083220.3	transmembrane prolyl 4-hydroxylase

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	P4HTM	XP_003432873.1
Mus musculus (house mouse)	P4htm	NP_083220.3
Danio rerio (zebrafish)	LOC799930	XP_001340234.2
Homo sapiens (human)	P4HTM	NP_808808.1
Gallus gallus (chicken)	P4HTM	XP_003642061.1
Xenopus tropicalis (tropical clawed frog)	p4htm	XP_002933103.2
Rattus norvegicus (Norway rat)	P4htm	XP_217285.6
Pan troglodytes (chimpanzee)	P4HTM	XP_001160922.1
Bos taurus (cattle)	P4HTM	NP_001069583.1

Gene Ontology
Bibliography

Related articles in PubMed

Lack of P4H-TM in mice results in age-related retinal and renal alterations.
Leinonen H, Rossi M, Salo AM, Tiainen P, Hyv?rinen J, Pitk?nen M, Sormunen R, Miinalainen I, Zhang C, Soininen R, Kivirikko KI, Koskelainen A, Tanila H, Myllyharju J, Koivunen P
Human molecular genetics25(17)3810-3823(2016 09)

Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis.
Laitala A, Aro E, Walkinshaw G, M?ki JM, Rossi M, Heikkil? M, Savolainen ER, Arend M, Kivirikko KI, Koivunen P, Myllyharju J
Blood120(16)3336-44(2012 Oct)

Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.
Hyv?rinen J, Hassinen IE, Sormunen R, M?ki JM, Kivirikko KI, Koivunen P, Myllyharju J
The Journal of biological chemistry285(18)13646-57(2010 Apr)

Effect of adiponectin overexpression on stability of preexisting plaques by inducing prolyl-4-hydroxylase expression.
Li L, Cai XJ, Feng M, Rong YY, Zhang Y, Zhang M
Circulation journal : official journal of the Japanese Circulation Society74(3)552-9(2010 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results show that P4h-tm is expressed to a high degree in the mouse retinal pigment epithelium (RPE) and brain. P4h-tm-/- mice develop age-related renal dysfunction, resulting in proteinuria and impaired RPE functions, which eventually lead to an AMD-like pathology.
Title: Lack of P4H-TM in mice results in age-related retinal and renal alterations.

chronic stabilization of Hif-1alpha and Hif-2alpha by genetic knockdown of Hif-p4h-2 promotes cardioprotection by induction of many genes involved in glucose metabolism, cardiac function, and blood pressure.
Title: Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.

Adiponectin increases collagen production by inducing the expression of P4H, which may play a major role in the development of the thick fibrous cap of advanced atherosclerotic plaque
Title: Effect of adiponectin overexpression on stability of preexisting plaques by inducing prolyl-4-hydroxylase expression.

The following P4HTM gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the P4HTM cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu83791	NM_001357465.1 Latest version!	Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu71171	XM_011242914.2 Latest version!	Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu06348	NM_028944.4 Latest version!	Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
View Old Accession Versions >>
OMu71171	XM_011242914.1	Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OMu06348	NM_028944.3	Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

P4HTM ( XM_011242914.1 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_011241216.1 Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu71171
Clone ID Related Accession (Same CDS sequence)	XM_011242914.2 , XM_011242914.1
Accession Version	XM_011242914.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	transmembrane prolyl 4-hydroxylase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGGGT TACAGCGAAG CCAGATCCTG CCCACTGAGG AGTATGAGGA GGCGATGAGC 
GCCATGCAGG TCAGCCAGCT GGACCTCTTC CAGCTGTTGG ATCAGAACCA CGACGGTCGC 
CTGCAGCTCC GAGAGGTCCT GGCCCAGACT CGCCTGGGAA ATGGACGGTG GATGACTCCA 
GAGAACATTC AGGAGATGTA CTCTGCAATC AAAGCAGACC CTGACGGTGA TGGCGTGCTG 
AGTCTGCAGG AATTTTCCAA CATGGACCTC CGAGACTTCC ACAAGTACAT GAGGAGCCAT 
AAGGCAGAAT CCAATGAGCT GGTGAGGAAC AGCCACCACA CATGGCTCCA CCAGGGAGAG 
GGAGCACATC ACGTCATGCG TGCCATCCGC CAGAGGGTCC TGCGCCTCAC TCGCCTCTCC 
CCGGAGATTG TGGAGTTCAG TGAGCCACTA CAGGTTGTAC GATATGGTGA GGGAGGTCAC 
TACCATGCCC ATGTGGACAG CGGACCCGTG TACCCAGAGA CCATCTGCTC CCATACCAAG 
CTGGTAGCCA ATGAATCTGT ACCGTTTGAG ACCTCCTGTC GCTACATGAC AGTGCTGTTT 
TATTTGAACA ATGTCACCGG TGGGGGTGAG ACCGTCTTCC CTGTGGCAGA CAACAGGACC 
TATGATGAAA TGAGTCTGAT TCAGGATGAT GTCGATCTCC GGGACACTCG AAGGCACTGT 
GACAAGGGCA ACCTTCGTGT CAAGCCCCAG CAAGGAACTG CAGTCTTTTG GTACAACTAC 
CTTCCTGATG GGCAAGGCTG GGTGGGTGAA GTGGACGACT ACTCGTTGCA TGGGGGCTGC 
CTGGTCACCC GCGGCACCAA GTGGATCGCT AACAACTGGA TCAATGTGGA CCCTAGCCGG 
GCACGGCAAG CCTTGTTCCA GCAGGAGATG GCTCGTCTGG CTCGGGAAGG TGGCATGGAC 
TCACAACCCG AGTGGGCCTT GGACCGAGCC TACAGTGATG CCCGTGTGGA GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011241216.1
CDS	275..1291
Translation	MKGLQRSQILPTEEYEEAMSAMQVSQLDLFQLLDQNHDGRLQLREVLAQTRLGNGRWMTPENIQEMYSAIKADPDGDGVLSLQEFSNMDLRDFHKYMRSHKAESNELVRNSHHTWLHQGEGAHHVMRAIRQRVLRLTRLSPEIVEFSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGEVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGMDSQPEWALDRAYSDARVEL

Target ORF information:

RefSeq Version	XM_011242914.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011242914.1

ORF Insert Sequence:

ATGAAAGGGT TACAGCGAAG CCAGATCCTG CCCACTGAGG AGTATGAGGA GGCGATGAGC 
GCCATGCAGG TCAGCCAGCT GGACCTCTTC CAGCTGTTGG ATCAGAACCA CGACGGTCGC 
CTGCAGCTCC GAGAGGTCCT GGCCCAGACT CGCCTGGGAA ATGGACGGTG GATGACTCCA 
GAGAACATTC AGGAGATGTA CTCTGCAATC AAAGCAGACC CTGACGGTGA TGGCGTGCTG 
AGTCTGCAGG AATTTTCCAA CATGGACCTC CGAGACTTCC ACAAGTACAT GAGGAGCCAT 
AAGGCAGAAT CCAATGAGCT GGTGAGGAAC AGCCACCACA CATGGCTCCA CCAGGGAGAG 
GGAGCACATC ACGTCATGCG TGCCATCCGC CAGAGGGTCC TGCGCCTCAC TCGCCTCTCC 
CCGGAGATTG TGGAGTTCAG TGAGCCACTA CAGGTTGTAC GATATGGTGA GGGAGGTCAC 
TACCATGCCC ATGTGGACAG CGGACCCGTG TACCCAGAGA CCATCTGCTC CCATACCAAG 
CTGGTAGCCA ATGAATCTGT ACCGTTTGAG ACCTCCTGTC GCTACATGAC AGTGCTGTTT 
TATTTGAACA ATGTCACCGG TGGGGGTGAG ACCGTCTTCC CTGTGGCAGA CAACAGGACC 
TATGATGAAA TGAGTCTGAT TCAGGATGAT GTCGATCTCC GGGACACTCG AAGGCACTGT 
GACAAGGGCA ACCTTCGTGT CAAGCCCCAG CAAGGAACTG CAGTCTTTTG GTACAACTAC 
CTTCCTGATG GGCAAGGCTG GGTGGGTGAA GTGGACGACT ACTCGTTGCA TGGGGGCTGC 
CTGGTCACCC GCGGCACCAA GTGGATCGCT AACAACTGGA TCAATGTGGA CCCTAGCCGG 
GCACGGCAAG CCTTGTTCCA GCAGGAGATG GCTCGTCTGG CTCGGGAAGG TGGCATGGAC 
TCACAACCCG AGTGGGCCTT GGACCGAGCC TACAGTGATG CCCGTGTGGA GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

P4HTM ( NM_001357465.1 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_001344394.1 Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu83791
Clone ID Related Accession (Same CDS sequence)	NM_001357465.1
Accession Version	NM_001357465.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-20
Organism	Mus musculus(house mouse)
Product	transmembrane prolyl 4-hydroxylase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK046783.1, BF471971.1 and CT571271.12. Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BF471971.1, BE945943.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAG CGGTGGCGAC CGTGCAGCGG CCTGAGGCTG AGACAGTCGA GGAGGCCTCA 
AATCTTCAGT GGCCGCTACC ACCGGAGCAT CGCCCTTCCG GGGCAGCGAC CAGACCAGGC 
GATAGTGAAG ACGCCCCGGT GCGGCCACTG TGCAAGCCGC GGGGCATCTG TTCCCGTGCC 
TACTTCTTGG TGCTGATGGT GTTCGTGCAC CTGTACTTGG GCAACGTGCT GGCCCTGCTG 
CTCTTCGTGC ACTACAGCAA CGGAGACGAG AGCACAGACC CCGGACCCCA GCGCCGCGAG 
CAGAGCCCCC AGCCAGTGCC AACCTTGGGT CCCCTCACCC GGCTGGAGGG CATCAAGGTG 
GGATATGAGC GGAAAGTCCA GGTGGTCGCG GGCAGGGATC ACTTCATCCG AACCCTCAGC 
CTCAAGCCGC TGCTTTTTGA AATCCCAGGC TTCCTGAGTG ACGAGGAGTG TCGGCTCATC 
ATCCACCTGG CACAGATGAA AGGGTTACAG CGAAGCCAGA TCCTGCCCAC TGAGGAGTAT 
GAGGAGGCGA TGAGCGCCAT GCAGGTCAGC CAGCTGGACC TCTTCCAGCT GTTGGATCAG 
AACCACGACG GTCGCCTGCA GCTCCGAGAG CAGGTCTGGG GATGGATATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001344394.1
CDS	49..699
Translation	MAAAVATVQRPEAETVEEASNLQWPLPPEHRPSGAATRPGDSEDAPVRPLCKPRGICSRAYFLVLMVFVHLYLGNVLALLLFVHYSNGDESTDPGPQRREQSPQPVPTLGPLTRLEGIKVGYERKVQVVAGRDHFIRTLSLKPLLFEIPGFLSDEECRLIIHLAQMKGLQRSQILPTEEYEEAMSAMQVSQLDLFQLLDQNHDGRLQLREQVWGWI

Target ORF information:

RefSeq Version	NM_001357465.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001357465.1

ORF Insert Sequence:

ATGGCGGCAG CGGTGGCGAC CGTGCAGCGG CCTGAGGCTG AGACAGTCGA GGAGGCCTCA 
AATCTTCAGT GGCCGCTACC ACCGGAGCAT CGCCCTTCCG GGGCAGCGAC CAGACCAGGC 
GATAGTGAAG ACGCCCCGGT GCGGCCACTG TGCAAGCCGC GGGGCATCTG TTCCCGTGCC 
TACTTCTTGG TGCTGATGGT GTTCGTGCAC CTGTACTTGG GCAACGTGCT GGCCCTGCTG 
CTCTTCGTGC ACTACAGCAA CGGAGACGAG AGCACAGACC CCGGACCCCA GCGCCGCGAG 
CAGAGCCCCC AGCCAGTGCC AACCTTGGGT CCCCTCACCC GGCTGGAGGG CATCAAGGTG 
GGATATGAGC GGAAAGTCCA GGTGGTCGCG GGCAGGGATC ACTTCATCCG AACCCTCAGC 
CTCAAGCCGC TGCTTTTTGA AATCCCAGGC TTCCTGAGTG ACGAGGAGTG TCGGCTCATC 
ATCCACCTGG CACAGATGAA AGGGTTACAG CGAAGCCAGA TCCTGCCCAC TGAGGAGTAT 
GAGGAGGCGA TGAGCGCCAT GCAGGTCAGC CAGCTGGACC TCTTCCAGCT GTTGGATCAG 
AACCACGACG GTCGCCTGCA GCTCCGAGAG CAGGTCTGGG GATGGATATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

P4HTM ( XM_011242914.2 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_011241216.1 Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu71171
Clone ID Related Accession (Same CDS sequence)	XM_011242914.2 , XM_011242914.1
Accession Version	XM_011242914.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	transmembrane prolyl 4-hydroxylase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011242914.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGGGT TACAGCGAAG CCAGATCCTG CCCACTGAGG AGTATGAGGA GGCGATGAGC 
GCCATGCAGG TCAGCCAGCT GGACCTCTTC CAGCTGTTGG ATCAGAACCA CGACGGTCGC 
CTGCAGCTCC GAGAGGTCCT GGCCCAGACT CGCCTGGGAA ATGGACGGTG GATGACTCCA 
GAGAACATTC AGGAGATGTA CTCTGCAATC AAAGCAGACC CTGACGGTGA TGGCGTGCTG 
AGTCTGCAGG AATTTTCCAA CATGGACCTC CGAGACTTCC ACAAGTACAT GAGGAGCCAT 
AAGGCAGAAT CCAATGAGCT GGTGAGGAAC AGCCACCACA CATGGCTCCA CCAGGGAGAG 
GGAGCACATC ACGTCATGCG TGCCATCCGC CAGAGGGTCC TGCGCCTCAC TCGCCTCTCC 
CCGGAGATTG TGGAGTTCAG TGAGCCACTA CAGGTTGTAC GATATGGTGA GGGAGGTCAC 
TACCATGCCC ATGTGGACAG CGGACCCGTG TACCCAGAGA CCATCTGCTC CCATACCAAG 
CTGGTAGCCA ATGAATCTGT ACCGTTTGAG ACCTCCTGTC GCTACATGAC AGTGCTGTTT 
TATTTGAACA ATGTCACCGG TGGGGGTGAG ACCGTCTTCC CTGTGGCAGA CAACAGGACC 
TATGATGAAA TGAGTCTGAT TCAGGATGAT GTCGATCTCC GGGACACTCG AAGGCACTGT 
GACAAGGGCA ACCTTCGTGT CAAGCCCCAG CAAGGAACTG CAGTCTTTTG GTACAACTAC 
CTTCCTGATG GGCAAGGCTG GGTGGGTGAA GTGGACGACT ACTCGTTGCA TGGGGGCTGC 
CTGGTCACCC GCGGCACCAA GTGGATCGCT AACAACTGGA TCAATGTGGA CCCTAGCCGG 
GCACGGCAAG CCTTGTTCCA GCAGGAGATG GCTCGTCTGG CTCGGGAAGG TGGCATGGAC 
TCACAACCCG AGTGGGCCTT GGACCGAGCC TACAGTGATG CCCGTGTGGA GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011241216.1
CDS	1171..2187
Translation	MKGLQRSQILPTEEYEEAMSAMQVSQLDLFQLLDQNHDGRLQLREVLAQTRLGNGRWMTPENIQEMYSAIKADPDGDGVLSLQEFSNMDLRDFHKYMRSHKAESNELVRNSHHTWLHQGEGAHHVMRAIRQRVLRLTRLSPEIVEFSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGEVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGMDSQPEWALDRAYSDARVEL

Target ORF information:

RefSeq Version	XM_011242914.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011242914.2

ORF Insert Sequence:

ATGAAAGGGT TACAGCGAAG CCAGATCCTG CCCACTGAGG AGTATGAGGA GGCGATGAGC 
GCCATGCAGG TCAGCCAGCT GGACCTCTTC CAGCTGTTGG ATCAGAACCA CGACGGTCGC 
CTGCAGCTCC GAGAGGTCCT GGCCCAGACT CGCCTGGGAA ATGGACGGTG GATGACTCCA 
GAGAACATTC AGGAGATGTA CTCTGCAATC AAAGCAGACC CTGACGGTGA TGGCGTGCTG 
AGTCTGCAGG AATTTTCCAA CATGGACCTC CGAGACTTCC ACAAGTACAT GAGGAGCCAT 
AAGGCAGAAT CCAATGAGCT GGTGAGGAAC AGCCACCACA CATGGCTCCA CCAGGGAGAG 
GGAGCACATC ACGTCATGCG TGCCATCCGC CAGAGGGTCC TGCGCCTCAC TCGCCTCTCC 
CCGGAGATTG TGGAGTTCAG TGAGCCACTA CAGGTTGTAC GATATGGTGA GGGAGGTCAC 
TACCATGCCC ATGTGGACAG CGGACCCGTG TACCCAGAGA CCATCTGCTC CCATACCAAG 
CTGGTAGCCA ATGAATCTGT ACCGTTTGAG ACCTCCTGTC GCTACATGAC AGTGCTGTTT 
TATTTGAACA ATGTCACCGG TGGGGGTGAG ACCGTCTTCC CTGTGGCAGA CAACAGGACC 
TATGATGAAA TGAGTCTGAT TCAGGATGAT GTCGATCTCC GGGACACTCG AAGGCACTGT 
GACAAGGGCA ACCTTCGTGT CAAGCCCCAG CAAGGAACTG CAGTCTTTTG GTACAACTAC 
CTTCCTGATG GGCAAGGCTG GGTGGGTGAA GTGGACGACT ACTCGTTGCA TGGGGGCTGC 
CTGGTCACCC GCGGCACCAA GTGGATCGCT AACAACTGGA TCAATGTGGA CCCTAGCCGG 
GCACGGCAAG CCTTGTTCCA GCAGGAGATG GCTCGTCTGG CTCGGGAAGG TGGCATGGAC 
TCACAACCCG AGTGGGCCTT GGACCGAGCC TACAGTGATG CCCGTGTGGA GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

P4HTM ( NM_028944.4 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_083220.3 Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu06348
Clone ID Related Accession (Same CDS sequence)	NM_028944.4 , NM_028944.3
Accession Version	NM_028944.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-20
Organism	Mus musculus(house mouse)
Product	transmembrane prolyl 4-hydroxylase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK046783.1 and BE944288.1. On Oct 28, 2017 this sequence version replaced NM_028944.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK046783.1, AK047714.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAG CGGTGGCGAC CGTGCAGCGG CCTGAGGCTG AGACAGTCGA GGAGGCCTCA 
AATCTTCAGT GGCCGCTACC ACCGGAGCAT CGCCCTTCCG GGGCAGCGAC CAGACCAGGC 
GATAGTGAAG ACGCCCCGGT GCGGCCACTG TGCAAGCCGC GGGGCATCTG TTCCCGTGCC 
TACTTCTTGG TGCTGATGGT GTTCGTGCAC CTGTACTTGG GCAACGTGCT GGCCCTGCTG 
CTCTTCGTGC ACTACAGCAA CGGAGACGAG AGCACAGACC CCGGACCCCA GCGCCGCGAG 
CAGAGCCCCC AGCCAGTGCC AACCTTGGGT CCCCTCACCC GGCTGGAGGG CATCAAGGTG 
GGATATGAGC GGAAAGTCCA GGTGGTCGCG GGCAGGGATC ACTTCATCCG AACCCTCAGC 
CTCAAGCCGC TGCTTTTTGA AATCCCAGGC TTCCTGAGTG ACGAGGAGTG TCGGCTCATC 
ATCCACCTGG CACAGATGAA AGGGTTACAG CGAAGCCAGA TCCTGCCCAC TGAGGAGTAT 
GAGGAGGCGA TGAGCGCCAT GCAGGTCAGC CAGCTGGACC TCTTCCAGCT GTTGGATCAG 
AACCACGACG GTCGCCTGCA GCTCCGAGAG GTCCTGGCCC AGACTCGCCT GGGAAATGGA 
CGGTGGATGA CTCCAGAGAA CATTCAGGAG ATGTACTCTG CAATCAAAGC AGACCCTGAC 
GGTGATGGCG TGCTGAGTCT GCAGGAATTT TCCAACATGG ACCTCCGAGA CTTCCACAAG 
TACATGAGGA GCCATAAGGC AGAATCCAAT GAGCTGGTGA GGAACAGCCA CCACACATGG 
CTCCACCAGG GAGAGGGAGC ACATCACGTC ATGCGTGCCA TCCGCCAGAG GGTCCTGCGC 
CTCACTCGCC TCTCCCCGGA GATTGTGGAG TTCAGTGAGC CACTACAGGT TGTACGATAT 
GGTGAGGGAG GTCACTACCA TGCCCATGTG GACAGCGGAC CCGTGTACCC AGAGACCATC 
TGCTCCCATA CCAAGCTGGT AGCCAATGAA TCTGTACCGT TTGAGACCTC CTGTCGCTAC 
ATGACAGTGC TGTTTTATTT GAACAATGTC ACCGGTGGGG GTGAGACCGT CTTCCCTGTG 
GCAGACAACA GGACCTATGA TGAAATGAGT CTGATTCAGG ATGATGTCGA TCTCCGGGAC 
ACTCGAAGGC ACTGTGACAA GGGCAACCTT CGTGTCAAGC CCCAGCAAGG AACTGCAGTC 
TTTTGGTACA ACTACCTTCC TGATGGGCAA GGCTGGGTGG GTGAAGTGGA CGACTACTCG 
TTGCATGGGG GCTGCCTGGT CACCCGCGGC ACCAAGTGGA TCGCTAACAA CTGGATCAAT 
GTGGACCCTA GCCGGGCACG GCAAGCCTTG TTCCAGCAGG AGATGGCTCG TCTGGCTCGG 
GAAGGTGGCA TGGACTCACA ACCCGAGTGG GCCTTGGACC GAGCCTACAG TGATGCCCGT 
GTGGAGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083220.3
CDS	49..1560
Translation	MAAAVATVQRPEAETVEEASNLQWPLPPEHRPSGAATRPGDSEDAPVRPLCKPRGICSRAYFLVLMVFVHLYLGNVLALLLFVHYSNGDESTDPGPQRREQSPQPVPTLGPLTRLEGIKVGYERKVQVVAGRDHFIRTLSLKPLLFEIPGFLSDEECRLIIHLAQMKGLQRSQILPTEEYEEAMSAMQVSQLDLFQLLDQNHDGRLQLREVLAQTRLGNGRWMTPENIQEMYSAIKADPDGDGVLSLQEFSNMDLRDFHKYMRSHKAESNELVRNSHHTWLHQGEGAHHVMRAIRQRVLRLTRLSPEIVEFSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGEVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGMDSQPEWALDRAYSDARVEL

Target ORF information:

RefSeq Version	NM_028944.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028944.4

ORF Insert Sequence:

ATGGCGGCAG CGGTGGCGAC CGTGCAGCGG CCTGAGGCTG AGACAGTCGA GGAGGCCTCA 
AATCTTCAGT GGCCGCTACC ACCGGAGCAT CGCCCTTCCG GGGCAGCGAC CAGACCAGGC 
GATAGTGAAG ACGCCCCGGT GCGGCCACTG TGCAAGCCGC GGGGCATCTG TTCCCGTGCC 
TACTTCTTGG TGCTGATGGT GTTCGTGCAC CTGTACTTGG GCAACGTGCT GGCCCTGCTG 
CTCTTCGTGC ACTACAGCAA CGGAGACGAG AGCACAGACC CCGGACCCCA GCGCCGCGAG 
CAGAGCCCCC AGCCAGTGCC AACCTTGGGT CCCCTCACCC GGCTGGAGGG CATCAAGGTG 
GGATATGAGC GGAAAGTCCA GGTGGTCGCG GGCAGGGATC ACTTCATCCG AACCCTCAGC 
CTCAAGCCGC TGCTTTTTGA AATCCCAGGC TTCCTGAGTG ACGAGGAGTG TCGGCTCATC 
ATCCACCTGG CACAGATGAA AGGGTTACAG CGAAGCCAGA TCCTGCCCAC TGAGGAGTAT 
GAGGAGGCGA TGAGCGCCAT GCAGGTCAGC CAGCTGGACC TCTTCCAGCT GTTGGATCAG 
AACCACGACG GTCGCCTGCA GCTCCGAGAG GTCCTGGCCC AGACTCGCCT GGGAAATGGA 
CGGTGGATGA CTCCAGAGAA CATTCAGGAG ATGTACTCTG CAATCAAAGC AGACCCTGAC 
GGTGATGGCG TGCTGAGTCT GCAGGAATTT TCCAACATGG ACCTCCGAGA CTTCCACAAG 
TACATGAGGA GCCATAAGGC AGAATCCAAT GAGCTGGTGA GGAACAGCCA CCACACATGG 
CTCCACCAGG GAGAGGGAGC ACATCACGTC ATGCGTGCCA TCCGCCAGAG GGTCCTGCGC 
CTCACTCGCC TCTCCCCGGA GATTGTGGAG TTCAGTGAGC CACTACAGGT TGTACGATAT 
GGTGAGGGAG GTCACTACCA TGCCCATGTG GACAGCGGAC CCGTGTACCC AGAGACCATC 
TGCTCCCATA CCAAGCTGGT AGCCAATGAA TCTGTACCGT TTGAGACCTC CTGTCGCTAC 
ATGACAGTGC TGTTTTATTT GAACAATGTC ACCGGTGGGG GTGAGACCGT CTTCCCTGTG 
GCAGACAACA GGACCTATGA TGAAATGAGT CTGATTCAGG ATGATGTCGA TCTCCGGGAC 
ACTCGAAGGC ACTGTGACAA GGGCAACCTT CGTGTCAAGC CCCAGCAAGG AACTGCAGTC 
TTTTGGTACA ACTACCTTCC TGATGGGCAA GGCTGGGTGG GTGAAGTGGA CGACTACTCG 
TTGCATGGGG GCTGCCTGGT CACCCGCGGC ACCAAGTGGA TCGCTAACAA CTGGATCAAT 
GTGGACCCTA GCCGGGCACG GCAAGCCTTG TTCCAGCAGG AGATGGCTCG TCTGGCTCGG 
GAAGGTGGCA TGGACTCACA ACCCGAGTGG GCCTTGGACC GAGCCTACAG TGATGCCCGT 
GTGGAGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

P4HTM ( NM_028944.3 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_083220.3 Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), mRNA.

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CloneID	OMu06348
Clone ID Related Accession (Same CDS sequence)	NM_028944.4 , NM_028944.3
Accession Version	NM_028944.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-22
Organism	Mus musculus(House mouse)
Product	transmembrane prolyl 4-hydroxylase
Comment	PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CT571271.12. On Mar 21, 2007 this sequence version replaced NM_028944.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK047714.1, AK046783.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCAG CGGTGGCGAC CGTGCAGCGG CCTGAGGCTG AGACAGTCGA GGAGGCCTCA 
AATCTTCAGT GGCCGCTACC ACCGGAGCAT CGCCCTTCCG GGGCAGCGAC CAGACCAGGC 
GATAGTGAAG ACGCCCCGGT GCGGCCACTG TGCAAGCCGC GGGGCATCTG TTCCCGTGCC 
TACTTCTTGG TGCTGATGGT GTTCGTGCAC CTGTACTTGG GCAACGTGCT GGCCCTGCTG 
CTCTTCGTGC ACTACAGCAA CGGAGACGAG AGCACAGACC CCGGACCCCA GCGCCGCGAG 
CAGAGCCCCC AGCCAGTGCC AACCTTGGGT CCCCTCACCC GGCTGGAGGG CATCAAGGTG 
GGATATGAGC GGAAAGTCCA GGTGGTCGCG GGCAGGGATC ACTTCATCCG AACCCTCAGC 
CTCAAGCCGC TGCTTTTTGA AATCCCAGGC TTCCTGAGTG ACGAGGAGTG TCGGCTCATC 
ATCCACCTGG CACAGATGAA AGGGTTACAG CGAAGCCAGA TCCTGCCCAC TGAGGAGTAT 
GAGGAGGCGA TGAGCGCCAT GCAGGTCAGC CAGCTGGACC TCTTCCAGCT GTTGGATCAG 
AACCACGACG GTCGCCTGCA GCTCCGAGAG GTCCTGGCCC AGACTCGCCT GGGAAATGGA 
CGGTGGATGA CTCCAGAGAA CATTCAGGAG ATGTACTCTG CAATCAAAGC AGACCCTGAC 
GGTGATGGCG TGCTGAGTCT GCAGGAATTT TCCAACATGG ACCTCCGAGA CTTCCACAAG 
TACATGAGGA GCCATAAGGC AGAATCCAAT GAGCTGGTGA GGAACAGCCA CCACACATGG 
CTCCACCAGG GAGAGGGAGC ACATCACGTC ATGCGTGCCA TCCGCCAGAG GGTCCTGCGC 
CTCACTCGCC TCTCCCCGGA GATTGTGGAG TTCAGTGAGC CACTACAGGT TGTACGATAT 
GGTGAGGGAG GTCACTACCA TGCCCATGTG GACAGCGGAC CCGTGTACCC AGAGACCATC 
TGCTCCCATA CCAAGCTGGT AGCCAATGAA TCTGTACCGT TTGAGACCTC CTGTCGCTAC 
ATGACAGTGC TGTTTTATTT GAACAATGTC ACCGGTGGGG GTGAGACCGT CTTCCCTGTG 
GCAGACAACA GGACCTATGA TGAAATGAGT CTGATTCAGG ATGATGTCGA TCTCCGGGAC 
ACTCGAAGGC ACTGTGACAA GGGCAACCTT CGTGTCAAGC CCCAGCAAGG AACTGCAGTC 
TTTTGGTACA ACTACCTTCC TGATGGGCAA GGCTGGGTGG GTGAAGTGGA CGACTACTCG 
TTGCATGGGG GCTGCCTGGT CACCCGCGGC ACCAAGTGGA TCGCTAACAA CTGGATCAAT 
GTGGACCCTA GCCGGGCACG GCAAGCCTTG TTCCAGCAGG AGATGGCTCG TCTGGCTCGG 
GAAGGTGGCA TGGACTCACA ACCCGAGTGG GCCTTGGACC GAGCCTACAG TGATGCCCGT 
GTGGAGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083220.3
CDS	37..1548
Translation	MAAAVATVQRPEAETVEEASNLQWPLPPEHRPSGAATRPGDSEDAPVRPLCKPRGICSRAYFLVLMVFVHLYLGNVLALLLFVHYSNGDESTDPGPQRREQSPQPVPTLGPLTRLEGIKVGYERKVQVVAGRDHFIRTLSLKPLLFEIPGFLSDEECRLIIHLAQMKGLQRSQILPTEEYEEAMSAMQVSQLDLFQLLDQNHDGRLQLREVLAQTRLGNGRWMTPENIQEMYSAIKADPDGDGVLSLQEFSNMDLRDFHKYMRSHKAESNELVRNSHHTWLHQGEGAHHVMRAIRQRVLRLTRLSPEIVEFSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGEVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGMDSQPEWALDRAYSDARVEL

Target ORF information:

RefSeq Version	NM_028944.3
Organism	Mus musculus(House mouse)
Definition	Mus musculus prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028944.3

ORF Insert Sequence:

ATGGCGGCAG CGGTGGCGAC CGTGCAGCGG CCTGAGGCTG AGACAGTCGA GGAGGCCTCA 
AATCTTCAGT GGCCGCTACC ACCGGAGCAT CGCCCTTCCG GGGCAGCGAC CAGACCAGGC 
GATAGTGAAG ACGCCCCGGT GCGGCCACTG TGCAAGCCGC GGGGCATCTG TTCCCGTGCC 
TACTTCTTGG TGCTGATGGT GTTCGTGCAC CTGTACTTGG GCAACGTGCT GGCCCTGCTG 
CTCTTCGTGC ACTACAGCAA CGGAGACGAG AGCACAGACC CCGGACCCCA GCGCCGCGAG 
CAGAGCCCCC AGCCAGTGCC AACCTTGGGT CCCCTCACCC GGCTGGAGGG CATCAAGGTG 
GGATATGAGC GGAAAGTCCA GGTGGTCGCG GGCAGGGATC ACTTCATCCG AACCCTCAGC 
CTCAAGCCGC TGCTTTTTGA AATCCCAGGC TTCCTGAGTG ACGAGGAGTG TCGGCTCATC 
ATCCACCTGG CACAGATGAA AGGGTTACAG CGAAGCCAGA TCCTGCCCAC TGAGGAGTAT 
GAGGAGGCGA TGAGCGCCAT GCAGGTCAGC CAGCTGGACC TCTTCCAGCT GTTGGATCAG 
AACCACGACG GTCGCCTGCA GCTCCGAGAG GTCCTGGCCC AGACTCGCCT GGGAAATGGA 
CGGTGGATGA CTCCAGAGAA CATTCAGGAG ATGTACTCTG CAATCAAAGC AGACCCTGAC 
GGTGATGGCG TGCTGAGTCT GCAGGAATTT TCCAACATGG ACCTCCGAGA CTTCCACAAG 
TACATGAGGA GCCATAAGGC AGAATCCAAT GAGCTGGTGA GGAACAGCCA CCACACATGG 
CTCCACCAGG GAGAGGGAGC ACATCACGTC ATGCGTGCCA TCCGCCAGAG GGTCCTGCGC 
CTCACTCGCC TCTCCCCGGA GATTGTGGAG TTCAGTGAGC CACTACAGGT TGTACGATAT 
GGTGAGGGAG GTCACTACCA TGCCCATGTG GACAGCGGAC CCGTGTACCC AGAGACCATC 
TGCTCCCATA CCAAGCTGGT AGCCAATGAA TCTGTACCGT TTGAGACCTC CTGTCGCTAC 
ATGACAGTGC TGTTTTATTT GAACAATGTC ACCGGTGGGG GTGAGACCGT CTTCCCTGTG 
GCAGACAACA GGACCTATGA TGAAATGAGT CTGATTCAGG ATGATGTCGA TCTCCGGGAC 
ACTCGAAGGC ACTGTGACAA GGGCAACCTT CGTGTCAAGC CCCAGCAAGG AACTGCAGTC 
TTTTGGTACA ACTACCTTCC TGATGGGCAA GGCTGGGTGG GTGAAGTGGA CGACTACTCG 
TTGCATGGGG GCTGCCTGGT CACCCGCGGC ACCAAGTGGA TCGCTAACAA CTGGATCAAT 
GTGGACCCTA GCCGGGCACG GCAAGCCTTG TTCCAGCAGG AGATGGCTCG TCTGGCTCGG 
GAAGGTGGCA TGGACTCACA ACCCGAGTGG GCCTTGGACC GAGCCTACAG TGATGCCCGT 
GTGGAGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lack of P4H-TM in mice results in age-related retinal and renal alterations.
Human molecular genetics25(17)3810-3823(2016 09)
Leinonen H,Rossi M,Salo AM,Tiainen P,Hyv?rinen J,Pitk?nen M,Sormunen R,Miinalainen I,Zhang C,Soininen R,Kivirikko KI,Koskelainen A,Tanila H,Myllyharju J,Koivunen P

Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis.
Blood120(16)3336-44(2012 Oct)
Laitala A,Aro E,Walkinshaw G,M?ki JM,Rossi M,Heikkil? M,Savolainen ER,Arend M,Kivirikko KI,Koivunen P,Myllyharju J

Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.
The Journal of biological chemistry285(18)13646-57(2010 Apr)
Hyv?rinen J,Hassinen IE,Sormunen R,M?ki JM,Kivirikko KI,Koivunen P,Myllyharju J

Effect of adiponectin overexpression on stability of preexisting plaques by inducing prolyl-4-hydroxylase expression.
Circulation journal : official journal of the Japanese Circulation Society74(3)552-9(2010 Mar)
Li L,Cai XJ,Feng M,Rong YY,Zhang Y,Zhang M

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P4HTM cDNA ORF clone, Mus musculus(House mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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