Pinx1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pinx1
Entrez Gene ID	72400
Full Name	PIN2/TERF1 interacting, telomerase inhibitor 1
Synonyms	2210403I16Rik,2610028A01Rik,67-11-3,AU024023,LPTS,LPTS1
General protein information	Preferred Names PIN2/TERF1 interacting, telomerase inhibitor 1 Names PIN2/TERF1-interacting telomerase inhibitor 1 PIN2-interacting protein X1 PIN2/TRF1-interacting protein TRF1-interacting protein 1 liver-related putative tumor suppressor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14\|14 D1

mRNA and Protein(s)

mRNA	Protein	Name
XM_030248045.1	XP_030103905.1	PIN2/TERF1-interacting telomerase inhibitor 1 isoform X2
NM_028228.3	NP_082504.1	PIN2/TERF1-interacting telomerase inhibitor 1
XM_006519595.3	XP_006519658.1	PIN2/TERF1-interacting telomerase inhibitor 1 isoform X1
XM_006519595.4	XP_006519658.1	PIN2/TERF1-interacting telomerase inhibitor 1 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	PINX1	NP_060354.4
	PINX1	XP_001089816.1
Rattus norvegicus (Norway rat)	Pinx1	NP_001076806.1
Canis lupus familiaris (dog)	PINX1	XP_003639935.1
Bos taurus (cattle)	PINX1	NP_001029725.1
Mus musculus (house mouse)	Pinx1	NP_082504.1

Gene Ontology
Bibliography

Related articles in PubMed

The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice.
Zhou XZ, Huang P, Shi R, Lee TH, Lu G, Zhang Z, Bronson R, Lu KP
The Journal of clinical investigation121(4)1266-82(2011 Apr)

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA
BMC developmental biology514(2005 Jul)

[The cloning and expression of a novel mouse gene mLPTS and its subcellular localization].
Liao C, Zhao MJ, Li ZP
Yi chuan xue bao = Acta genetica Sinica29(10)865-70(2002 Oct)

The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor.
Zhou XZ, Lu KP
Cell107(3)347-59(2001 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PinX1 heterozygosity and PinX1 knockdown in mouse embryonic fibroblasts activated telomerase and led to concomitant telomerase-dependent chromosomal instability.
Title: The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice.

The following Pinx1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pinx1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05362	NM_028228.3 Latest version!	Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu50379	XM_006519595.4 Latest version!	Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu86502	XM_030248045.1 Latest version!	Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu50379	XM_006519595.3	Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pinx1 ( NM_028228.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082504.1 Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), mRNA.

Price & Availability↑

CloneID	OMu05362
Clone ID Related Accession (Same CDS sequence)	NM_028228.3
Accession Version	NM_028228.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	PIN2/TERF1-interacting telomerase inhibitor 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC118607.12, AK012057.1, AK075840.1 and AK011578.1. On Oct 28, 2009 this sequence version replaced NM_028228.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AF321817.1, BC115636.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGTCGATGC TAGCAGAGCG GCGGCGGAAG CAGAAATGGA CTGTGGATCC CAGAAACACC 
GCGTGGAGTA ACGATGATTC CAAGTTTGGC CAGAAGATGC TTGAGAAGAT GGGGTGGTCT 
AAAGGAAAGG GTTTGGGAGC TCAGGAGCAA GGAGCCACAG AACATATTAA AGTTAAAGTT 
AAAAATAACC ACCTGGGACT TGGAGCTACA AACAATAATG AAGACAACTG GATTGCTCAC 
CAGGATGACT TCAACCAGCT TTTGGCAGCA CTCAACACTT GCCACGGTCA GGAAACAGCA 
GATTCCTCAG ACAAAAAGGA AAAGAAATCT TTTAGCCTTG AAGAAAAATC CAAAATCTCC 
AAAAACCGGG TTCATTATAT GAAATTCACA AAAGGGAAGG ATCTGTCCTC TCGGAGTGAA 
ACCGACCTGG ACTGCATTTT TGGAAAAAGG AGGAACAAGA AGCTTGCTCA GGATGGCTGC 
AGCAACTCCT CTGCGGATGA GGTGAACACC TCCCTGACCA CAACCACGAC CACCACTAGT 
GCCTTCACCA TCCAGGAATA TTTTGCCAAG AGAATGGCCC AATTAAAGAA CAAGCCACAA 
GCCTCAGCTC CAGGGTCTGA CCTTTCAGAG ACCCCTGTTG AAAGGAAAAA GGGAAAGAAA 
AAAAACAAAG AGGCAGCAGA CACAGATGTA GAGAACTCTC CCCAACACAA GGCCAAGAGG 
CATAAAAAGA AAAAGCGTGT GGAAGCAGAG AGGGGCCCTG TGGCCAAGAA GAGAGACCGA 
GCAGAGCTGC AGCCTGGAGG CCCCAGTGAG GACGAGTGTT CCGATGCCTC TGTCGAAGCT 
GCAGAAGATT GTGTACAAAC ACCAGACATC CAGGATGATG TCCCAAAGCC CAAGAAGAGG 
AAAGCAAAGA AAAAGCTGCA AAGGCCAGAA GGAGTAGAAA TAGACGCCAC ACTAGACAGA 
GCACCGGTGA AAAAGAAGAA GAAGAAAGTT TCCAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082504.1
CDS	118..1116
Translation	MSMLAERRRKQKWTVDPRNTAWSNDDSKFGQKMLEKMGWSKGKGLGAQEQGATEHIKVKVKNNHLGLGATNNNEDNWIAHQDDFNQLLAALNTCHGQETADSSDKKEKKSFSLEEKSKISKNRVHYMKFTKGKDLSSRSETDLDCIFGKRRNKKLAQDGCSNSSADEVNTSLTTTTTTTSAFTIQEYFAKRMAQLKNKPQASAPGSDLSETPVERKKGKKKNKEAADTDVENSPQHKAKRHKKKKRVEAERGPVAKKRDRAELQPGGPSEDECSDASVEAAEDCVQTPDIQDDVPKPKKRKAKKKLQRPEGVEIDATLDRAPVKKKKKKVSR

Target ORF information:

RefSeq Version	NM_028228.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028228.3

ORF Insert Sequence:

ATGTCGATGC TAGCAGAGCG GCGGCGGAAG CAGAAATGGA CTGTGGATCC CAGAAACACC 
GCGTGGAGTA ACGATGATTC CAAGTTTGGC CAGAAGATGC TTGAGAAGAT GGGGTGGTCT 
AAAGGAAAGG GTTTGGGAGC TCAGGAGCAA GGAGCCACAG AACATATTAA AGTTAAAGTT 
AAAAATAACC ACCTGGGACT TGGAGCTACA AACAATAATG AAGACAACTG GATTGCTCAC 
CAGGATGACT TCAACCAGCT TTTGGCAGCA CTCAACACTT GCCACGGTCA GGAAACAGCA 
GATTCCTCAG ACAAAAAGGA AAAGAAATCT TTTAGCCTTG AAGAAAAATC CAAAATCTCC 
AAAAACCGGG TTCATTATAT GAAATTCACA AAAGGGAAGG ATCTGTCCTC TCGGAGTGAA 
ACCGACCTGG ACTGCATTTT TGGAAAAAGG AGGAACAAGA AGCTTGCTCA GGATGGCTGC 
AGCAACTCCT CTGCGGATGA GGTGAACACC TCCCTGACCA CAACCACGAC CACCACTAGT 
GCCTTCACCA TCCAGGAATA TTTTGCCAAG AGAATGGCCC AATTAAAGAA CAAGCCACAA 
GCCTCAGCTC CAGGGTCTGA CCTTTCAGAG ACCCCTGTTG AAAGGAAAAA GGGAAAGAAA 
AAAAACAAAG AGGCAGCAGA CACAGATGTA GAGAACTCTC CCCAACACAA GGCCAAGAGG 
CATAAAAAGA AAAAGCGTGT GGAAGCAGAG AGGGGCCCTG TGGCCAAGAA GAGAGACCGA 
GCAGAGCTGC AGCCTGGAGG CCCCAGTGAG GACGAGTGTT CCGATGCCTC TGTCGAAGCT 
GCAGAAGATT GTGTACAAAC ACCAGACATC CAGGATGATG TCCCAAAGCC CAAGAAGAGG 
AAAGCAAAGA AAAAGCTGCA AAGGCCAGAA GGAGTAGAAA TAGACGCCAC ACTAGACAGA 
GCACCGGTGA AAAAGAAGAA GAAGAAAGTT TCCAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pinx1 ( XM_006519595.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006519658.1 Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu50379
Clone ID Related Accession (Same CDS sequence)	XM_006519595.3 , XM_006519595.4
Accession Version	XM_006519595.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	PIN2/TERF1-interacting telomerase inhibitor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006519595.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGATGC TAGCAGAGCG GCGGCGGAAG CAGAAATGGA CTGTGGATCC CAGAAACACC 
GCGTGGAGTA ACGATGATTC CAAGTTTGGC CAGAAGATGC TTGAGAAGAT GGGGTGGTCT 
AAAGGAAAGG GTTTGGGAGC TCAGGAGCAA GGAGCCACAG AACATATTAA AGTTAAAGTT 
AAAAATAACC ACCTGGGACT TGGAGCTACA AACAATAATG AAGACAACTG GATTGCTCAC 
CAGGATGACT TCAACCAGCT TTTGGCAGCA CTCAACACTT GCCACGGTCA GGAAACAGCA 
GGGAAGGATC TGTCCTCTCG GAGTGAAACC GACCTGGACT GCATTTTTGG AAAAAGGAGG 
AACAAGAAGC TTGCTCAGGA TGGCTGCAGC AACTCCTCTG CGGATGAGGT GAACACCTCC 
CTGACCACAA CCACGACCAC CACTAGTGCC TTCACCATCC AGGAATATTT TGCCAAGAGA 
ATGGCCCAAT TAAAGAACAA GCCACAAGCC TCAGCTCCAG GGTCTGACCT TTCAGAGACC 
CCTGTTGAAA GGAAAAAGGG AAAGAAAAAA AACAAAGAGG CAGCAGACAC AGATGTAGAG 
AACTCTCCCC AACACAAGGC CAAGAGGCAT AAAAAGAAAA AGCGTGTGGA AGCAGAGAGG 
GGCCCTGTGG CCAAGAAGAG AGACCGAGCA GAGCTGCAGC CTGGAGGCCC CAGTGAGGAC 
GAGTGTTCCG ATGCCTCTGT CGAAGCTGCA GAAGATTGTG TACAAACACC AGACATCCAG 
GATGATGTCC CAAAGCCCAA GAAGAGGAAA GCAAAGAAAA AGCTGCAAAG GCCAGAAGGA 
GTAGAAATAG ACGCCACACT AGACAGAGCA CCGGTGAAAA AGAAGAAGAA GAAAGTTTCC 
AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006519658.1
CDS	127..1032
Translation	MSMLAERRRKQKWTVDPRNTAWSNDDSKFGQKMLEKMGWSKGKGLGAQEQGATEHIKVKVKNNHLGLGATNNNEDNWIAHQDDFNQLLAALNTCHGQETAGKDLSSRSETDLDCIFGKRRNKKLAQDGCSNSSADEVNTSLTTTTTTTSAFTIQEYFAKRMAQLKNKPQASAPGSDLSETPVERKKGKKKNKEAADTDVENSPQHKAKRHKKKKRVEAERGPVAKKRDRAELQPGGPSEDECSDASVEAAEDCVQTPDIQDDVPKPKKRKAKKKLQRPEGVEIDATLDRAPVKKKKKKVSR

Target ORF information:

RefSeq Version	XM_006519595.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006519595.3

ORF Insert Sequence:

ATGTCGATGC TAGCAGAGCG GCGGCGGAAG CAGAAATGGA CTGTGGATCC CAGAAACACC 
GCGTGGAGTA ACGATGATTC CAAGTTTGGC CAGAAGATGC TTGAGAAGAT GGGGTGGTCT 
AAAGGAAAGG GTTTGGGAGC TCAGGAGCAA GGAGCCACAG AACATATTAA AGTTAAAGTT 
AAAAATAACC ACCTGGGACT TGGAGCTACA AACAATAATG AAGACAACTG GATTGCTCAC 
CAGGATGACT TCAACCAGCT TTTGGCAGCA CTCAACACTT GCCACGGTCA GGAAACAGCA 
GGGAAGGATC TGTCCTCTCG GAGTGAAACC GACCTGGACT GCATTTTTGG AAAAAGGAGG 
AACAAGAAGC TTGCTCAGGA TGGCTGCAGC AACTCCTCTG CGGATGAGGT GAACACCTCC 
CTGACCACAA CCACGACCAC CACTAGTGCC TTCACCATCC AGGAATATTT TGCCAAGAGA 
ATGGCCCAAT TAAAGAACAA GCCACAAGCC TCAGCTCCAG GGTCTGACCT TTCAGAGACC 
CCTGTTGAAA GGAAAAAGGG AAAGAAAAAA AACAAAGAGG CAGCAGACAC AGATGTAGAG 
AACTCTCCCC AACACAAGGC CAAGAGGCAT AAAAAGAAAA AGCGTGTGGA AGCAGAGAGG 
GGCCCTGTGG CCAAGAAGAG AGACCGAGCA GAGCTGCAGC CTGGAGGCCC CAGTGAGGAC 
GAGTGTTCCG ATGCCTCTGT CGAAGCTGCA GAAGATTGTG TACAAACACC AGACATCCAG 
GATGATGTCC CAAAGCCCAA GAAGAGGAAA GCAAAGAAAA AGCTGCAAAG GCCAGAAGGA 
GTAGAAATAG ACGCCACACT AGACAGAGCA CCGGTGAAAA AGAAGAAGAA GAAAGTTTCC 
AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pinx1 ( XM_006519595.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006519658.1 Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu50379
Clone ID Related Accession (Same CDS sequence)	XM_006519595.3 , XM_006519595.4
Accession Version	XM_006519595.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	PIN2/TERF1-interacting telomerase inhibitor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006519595.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGATGC TAGCAGAGCG GCGGCGGAAG CAGAAATGGA CTGTGGATCC CAGAAACACC 
GCGTGGAGTA ACGATGATTC CAAGTTTGGC CAGAAGATGC TTGAGAAGAT GGGGTGGTCT 
AAAGGAAAGG GTTTGGGAGC TCAGGAGCAA GGAGCCACAG AACATATTAA AGTTAAAGTT 
AAAAATAACC ACCTGGGACT TGGAGCTACA AACAATAATG AAGACAACTG GATTGCTCAC 
CAGGATGACT TCAACCAGCT TTTGGCAGCA CTCAACACTT GCCACGGTCA GGAAACAGCA 
GGGAAGGATC TGTCCTCTCG GAGTGAAACC GACCTGGACT GCATTTTTGG AAAAAGGAGG 
AACAAGAAGC TTGCTCAGGA TGGCTGCAGC AACTCCTCTG CGGATGAGGT GAACACCTCC 
CTGACCACAA CCACGACCAC CACTAGTGCC TTCACCATCC AGGAATATTT TGCCAAGAGA 
ATGGCCCAAT TAAAGAACAA GCCACAAGCC TCAGCTCCAG GGTCTGACCT TTCAGAGACC 
CCTGTTGAAA GGAAAAAGGG AAAGAAAAAA AACAAAGAGG CAGCAGACAC AGATGTAGAG 
AACTCTCCCC AACACAAGGC CAAGAGGCAT AAAAAGAAAA AGCGTGTGGA AGCAGAGAGG 
GGCCCTGTGG CCAAGAAGAG AGACCGAGCA GAGCTGCAGC CTGGAGGCCC CAGTGAGGAC 
GAGTGTTCCG ATGCCTCTGT CGAAGCTGCA GAAGATTGTG TACAAACACC AGACATCCAG 
GATGATGTCC CAAAGCCCAA GAAGAGGAAA GCAAAGAAAA AGCTGCAAAG GCCAGAAGGA 
GTAGAAATAG ACGCCACACT AGACAGAGCA CCGGTGAAAA AGAAGAAGAA GAAAGTTTCC 
AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006519658.1
CDS	148..1053
Translation	MSMLAERRRKQKWTVDPRNTAWSNDDSKFGQKMLEKMGWSKGKGLGAQEQGATEHIKVKVKNNHLGLGATNNNEDNWIAHQDDFNQLLAALNTCHGQETAGKDLSSRSETDLDCIFGKRRNKKLAQDGCSNSSADEVNTSLTTTTTTTSAFTIQEYFAKRMAQLKNKPQASAPGSDLSETPVERKKGKKKNKEAADTDVENSPQHKAKRHKKKKRVEAERGPVAKKRDRAELQPGGPSEDECSDASVEAAEDCVQTPDIQDDVPKPKKRKAKKKLQRPEGVEIDATLDRAPVKKKKKKVSR

Target ORF information:

RefSeq Version	XM_006519595.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006519595.4

ORF Insert Sequence:

ATGTCGATGC TAGCAGAGCG GCGGCGGAAG CAGAAATGGA CTGTGGATCC CAGAAACACC 
GCGTGGAGTA ACGATGATTC CAAGTTTGGC CAGAAGATGC TTGAGAAGAT GGGGTGGTCT 
AAAGGAAAGG GTTTGGGAGC TCAGGAGCAA GGAGCCACAG AACATATTAA AGTTAAAGTT 
AAAAATAACC ACCTGGGACT TGGAGCTACA AACAATAATG AAGACAACTG GATTGCTCAC 
CAGGATGACT TCAACCAGCT TTTGGCAGCA CTCAACACTT GCCACGGTCA GGAAACAGCA 
GGGAAGGATC TGTCCTCTCG GAGTGAAACC GACCTGGACT GCATTTTTGG AAAAAGGAGG 
AACAAGAAGC TTGCTCAGGA TGGCTGCAGC AACTCCTCTG CGGATGAGGT GAACACCTCC 
CTGACCACAA CCACGACCAC CACTAGTGCC TTCACCATCC AGGAATATTT TGCCAAGAGA 
ATGGCCCAAT TAAAGAACAA GCCACAAGCC TCAGCTCCAG GGTCTGACCT TTCAGAGACC 
CCTGTTGAAA GGAAAAAGGG AAAGAAAAAA AACAAAGAGG CAGCAGACAC AGATGTAGAG 
AACTCTCCCC AACACAAGGC CAAGAGGCAT AAAAAGAAAA AGCGTGTGGA AGCAGAGAGG 
GGCCCTGTGG CCAAGAAGAG AGACCGAGCA GAGCTGCAGC CTGGAGGCCC CAGTGAGGAC 
GAGTGTTCCG ATGCCTCTGT CGAAGCTGCA GAAGATTGTG TACAAACACC AGACATCCAG 
GATGATGTCC CAAAGCCCAA GAAGAGGAAA GCAAAGAAAA AGCTGCAAAG GCCAGAAGGA 
GTAGAAATAG ACGCCACACT AGACAGAGCA CCGGTGAAAA AGAAGAAGAA GAAAGTTTCC 
AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pinx1 ( XM_030248045.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030103905.1 Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu86502
Clone ID Related Accession (Same CDS sequence)	XM_030248045.1
Accession Version	XM_030248045.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 756bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	PIN2/TERF1-interacting telomerase inhibitor 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTCCAA GTTTGGCCAG AAGATGCTTG AGAAGATGGG GTGGTCTAAA GGAAAGGGTT 
TGGGAGCTCA GGAGCAAGGA GCCACAGAAC ATATTAAAGT TAAAGTTAAA AATAACCACC 
TGGGACTTGG AGCTACAAAC AATAATGAAG ACAACTGGAT TGCTCACCAG GATGACTTCA 
ACCAGCTTTT GGCAGCACTC AACACTTGCC ACGGTCAGGA AACAGCAGGA TGGCTGCAGC 
AACTCCTCTG CGGATGAGGT GAACACCTCC CTGACCACAA CCACGACCAC CACTAGTGCC 
TTCACCATCC AGGAATATTT TGCCAAGAGA ATGGCCCAAT TAAAGAACAA GCCACAAGCC 
TCAGCTCCAG GGTCTGACCT TTCAGAGACC CCTGTTGAAA GGAAAAAGGG AAAGAAAAAA 
AACAAAGAGG CAGCAGACAC AGATGTAGAG AACTCTCCCC AACACAAGGC CAAGAGGCAT 
AAAAAGAAAA AGCGTGTGGA AGCAGAGAGG GGCCCTGTGG CCAAGAAGAG AGACCGAGCA 
GAGCTGCAGC CTGGAGGCCC CAGTGAGGAC GAGTGTTCCG ATGCCTCTGT CGAAGCTGCA 
GAAGATTGTG TACAAACACC AGACATCCAG GATGATGTCC CAAAGCCCAA GAAGAGGAAA 
GCAAAGAAAA AGCTGCAAAG GCCAGAAGGA GTAGAAATAG ACGCCACACT AGACAGAGCA 
CCGGTGAAAA AGAAGAAGAA GAAAGTTTCC AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030103905.1
CDS	170..925
Translation	MIPSLARRCLRRWGGLKERVWELRSKEPQNILKLKLKITTWDLELQTIMKTTGLLTRMTSTSFWQHSTLATVRKQQDGCSNSSADEVNTSLTTTTTTTSAFTIQEYFAKRMAQLKNKPQASAPGSDLSETPVERKKGKKKNKEAADTDVENSPQHKAKRHKKKKRVEAERGPVAKKRDRAELQPGGPSEDECSDASVEAAEDCVQTPDIQDDVPKPKKRKAKKKLQRPEGVEIDATLDRAPVKKKKKKVSR

Target ORF information:

RefSeq Version	XM_030248045.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030248045.1

ORF Insert Sequence:

ATGATTCCAA GTTTGGCCAG AAGATGCTTG AGAAGATGGG GTGGTCTAAA GGAAAGGGTT 
TGGGAGCTCA GGAGCAAGGA GCCACAGAAC ATATTAAAGT TAAAGTTAAA AATAACCACC 
TGGGACTTGG AGCTACAAAC AATAATGAAG ACAACTGGAT TGCTCACCAG GATGACTTCA 
ACCAGCTTTT GGCAGCACTC AACACTTGCC ACGGTCAGGA AACAGCAGGA TGGCTGCAGC 
AACTCCTCTG CGGATGAGGT GAACACCTCC CTGACCACAA CCACGACCAC CACTAGTGCC 
TTCACCATCC AGGAATATTT TGCCAAGAGA ATGGCCCAAT TAAAGAACAA GCCACAAGCC 
TCAGCTCCAG GGTCTGACCT TTCAGAGACC CCTGTTGAAA GGAAAAAGGG AAAGAAAAAA 
AACAAAGAGG CAGCAGACAC AGATGTAGAG AACTCTCCCC AACACAAGGC CAAGAGGCAT 
AAAAAGAAAA AGCGTGTGGA AGCAGAGAGG GGCCCTGTGG CCAAGAAGAG AGACCGAGCA 
GAGCTGCAGC CTGGAGGCCC CAGTGAGGAC GAGTGTTCCG ATGCCTCTGT CGAAGCTGCA 
GAAGATTGTG TACAAACACC AGACATCCAG GATGATGTCC CAAAGCCCAA GAAGAGGAAA 
GCAAAGAAAA AGCTGCAAAG GCCAGAAGGA GTAGAAATAG ACGCCACACT AGACAGAGCA 
CCGGTGAAAA AGAAGAAGAA GAAAGTTTCC AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice.
The Journal of clinical investigation121(4)1266-82(2011 Apr)
Zhou XZ,Huang P,Shi R,Lee TH,Lu G,Zhang Z,Bronson R,Lu KP

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
BMC developmental biology514(2005 Jul)
McKee AE,Minet E,Stern C,Riahi S,Stiles CD,Silver PA

[The cloning and expression of a novel mouse gene mLPTS and its subcellular localization].
Yi chuan xue bao = Acta genetica Sinica29(10)865-70(2002 Oct)
Liao C,Zhao MJ,Li ZP

The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor.
Cell107(3)347-59(2001 Nov)
Zhou XZ,Lu KP