Pllp cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pllp
Entrez Gene ID	67801
Full Name	plasma membrane proteolipid
Synonyms	0610010I06Rik,AV001002,Plapi,Tm4sf11
General protein information	Preferred Names plasma membrane proteolipid Names plasmolipin transmembrane 4 superfamily member 11
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 C5

mRNA and Protein(s)

mRNA	Protein	Name
NM_026385.4	NP_080661.1	plasmolipin

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	PLLP	NP_001025732.1
Xenopus tropicalis (tropical clawed frog)	LOC100493581	XP_002931714.1
Canis lupus familiaris (dog)	PLLP	XP_003433877.2
Rattus norvegicus (Norway rat)	Pllp	NP_071978.1
Homo sapiens (human)	PLLP	NP_057077.1
Danio rerio (zebrafish)	si:dkey-73n10.4	NP_001116171.1
Bos taurus (cattle)	PLLP	NP_001092593.1
Pan troglodytes (chimpanzee)	PLLP	XP_001145227.1
Mus musculus (house mouse)	Pllp	NP_080661.1

Gene Ontology
Bibliography

Related articles in PubMed

Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular?organs.
Rodr?guez-Fraticelli AE, Bagwell J, Bosch-Fortea M, Boncompain G, Reglero-Real N, Garc?a-Le?n MJ, Andr?s G, Toribio ML, Alonso MA, Mill?n J, Perez F, Bagnat M, Mart?n-Belmonte F
Nature cell biology17(3)241-50(2015 Mar)

Identification of the myelin protein plasmolipin as the cell entry receptor for Mus caroli endogenous retrovirus.
Miller AD, Bergholz U, Ziegler M, Stocking C
Journal of virology82(14)6862-8(2008 Jul)

Plasmolipin: genomic structure, chromosomal localization, protein expression pattern, and putative association with Bardet-Biedl syndrome.
Hamacher M, Pippirs U, K?hler A, M?ller HW, Bosse F
Mammalian genome : official journal of the International Mammalian Genome Society12(12)933-7(2001 Dec)

Structure and in vitro transcription of a mouse B1 cluster containing a unique B1 dimer.
Moshier JA, Deutch AH, Huang RC
Gene58(1)19-27(1987)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PLLP recruits the clathrin adaptor EpsinR to sort the SNARE machinery of the endolysosomal pathway into the subapical compartment, which is a switch for polarized endocytosis.
Title: Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular?organs.

mouse PLLP also functioned well as a receptor for McERV but was simply not expressed in the mouse cell types that we originally tested.
Title: Identification of the myelin protein plasmolipin as the cell entry receptor for Mus caroli endogenous retrovirus.

The following Pllp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pllp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu02154	NM_026385.4 Latest version!	Mus musculus plasma membrane proteolipid (Pllp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pllp ( NM_026385.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080661.1 Mus musculus plasma membrane proteolipid (Pllp), mRNA.

Price & Availability↑

CloneID	OMu02154
Clone ID Related Accession (Same CDS sequence)	NM_026385.4
Accession Version	NM_026385.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	plasmolipin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK002477.1. On Apr 6, 2007 this sequence version replaced NM_026385.3. ##Evidence-Data-START## Transcript exon combination :: AK002477.1, BC024534.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGAGT TCCCGTCGAA AGTGAGCACG AGGACCAGCA GCCCCGCGCA GGGCGTGGGA 
GCCTCTGTGT CTGCGCTGCG ACCGGATCTG GGCTTCGTGC GCTCCGCTCT TGGGGTGCTC 
GCGCTTCTGC AGCTGGCACT GGGGCTGCTG GTGTGGGCCC TGATTGCTGA CACCCCATAC 
CATCTGTATC CTGCCTATGG CTGGGTCATG TTTGTCGCTG TCTTCCTCTG GCTGGTGACA 
ATCGTCTTCT TCATCATCTA CCTGTTTCAA CTGCACATGA AGTTGTACAT GGTGCCCTGG 
CCGTTGGTGT TACTGATCTT TTTTGTCGCT GCCACGGTTC TCTACATTAC TGCCTTTATC 
GCCTGTGCAG CGGCGGTCGA TCTGACATCC CTGAGGGGCT CCCGGCCATA TAACCAGCGC 
TCAGCTGCCT CTTTCTTTGC TTGTCTGGTG ATGATTGCCT ACGGAGTGAG CGCTTTCTTC 
AGCTTCCAGG CCTGGCGAGG AGTGGGTAGC AACGCGGCCA CGAGTCAGAT GGCTGGGGGC 
TACTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080661.1
CDS	73..621
Translation	MAEFPSKVSTRTSSPAQGVGASVSALRPDLGFVRSALGVLALLQLALGLLVWALIADTPYHLYPAYGWVMFVAVFLWLVTIVFFIIYLFQLHMKLYMVPWPLVLLIFFVAATVLYITAFIACAAAVDLTSLRGSRPYNQRSAASFFACLVMIAYGVSAFFSFQAWRGVGSNAATSQMAGGYS

Target ORF information:

RefSeq Version	NM_026385.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus plasma membrane proteolipid (Pllp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026385.4

ORF Insert Sequence:

ATGGCGGAGT TCCCGTCGAA AGTGAGCACG AGGACCAGCA GCCCCGCGCA GGGCGTGGGA 
GCCTCTGTGT CTGCGCTGCG ACCGGATCTG GGCTTCGTGC GCTCCGCTCT TGGGGTGCTC 
GCGCTTCTGC AGCTGGCACT GGGGCTGCTG GTGTGGGCCC TGATTGCTGA CACCCCATAC 
CATCTGTATC CTGCCTATGG CTGGGTCATG TTTGTCGCTG TCTTCCTCTG GCTGGTGACA 
ATCGTCTTCT TCATCATCTA CCTGTTTCAA CTGCACATGA AGTTGTACAT GGTGCCCTGG 
CCGTTGGTGT TACTGATCTT TTTTGTCGCT GCCACGGTTC TCTACATTAC TGCCTTTATC 
GCCTGTGCAG CGGCGGTCGA TCTGACATCC CTGAGGGGCT CCCGGCCATA TAACCAGCGC 
TCAGCTGCCT CTTTCTTTGC TTGTCTGGTG ATGATTGCCT ACGGAGTGAG CGCTTTCTTC 
AGCTTCCAGG CCTGGCGAGG AGTGGGTAGC AACGCGGCCA CGAGTCAGAT GGCTGGGGGC 
TACTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular?organs.
Nature cell biology17(3)241-50(2015 Mar)
Rodr?guez-Fraticelli AE,Bagwell J,Bosch-Fortea M,Boncompain G,Reglero-Real N,Garc?a-Le?n MJ,Andr?s G,Toribio ML,Alonso MA,Mill?n J,Perez F,Bagnat M,Mart?n-Belmonte F

Identification of the myelin protein plasmolipin as the cell entry receptor for Mus caroli endogenous retrovirus.
Journal of virology82(14)6862-8(2008 Jul)
Miller AD,Bergholz U,Ziegler M,Stocking C

Plasmolipin: genomic structure, chromosomal localization, protein expression pattern, and putative association with Bardet-Biedl syndrome.
Mammalian genome : official journal of the International Mammalian Genome Society12(12)933-7(2001 Dec)
Hamacher M,Pippirs U,K?hler A,M?ller HW,Bosse F

Structure and in vitro transcription of a mouse B1 cluster containing a unique B1 dimer.
Gene58(1)19-27(1987)
Moshier JA,Deutch AH,Huang RC