Cuta cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cuta
Entrez Gene ID	67675
Full Name	cutA divalent cation tolerance homolog
Synonyms	0610039D01Rik,1810022E02Rik,1810060C03Rik,2700094G22Rik,AI326454
General protein information	Preferred Names cutA divalent cation tolerance homolog Names protein CutA brain acetylcholinesterase putative membrane anchor divalent cation tolerant protein CUTA
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17\|17 A3.3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006524832.3	XP_006524895.1	protein CutA isoform X1
NM_026948.3	NP_081224.1	protein CutA isoform 2 precursor
XM_030250013.1	XP_030105873.1	protein CutA isoform X1
XM_006524832.4	XP_006524895.1	protein CutA isoform X2
NM_026307.3	NP_080583.3	protein CutA isoform 1 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CUTA	XP_863515.1
Bos taurus (cattle)	CUTA	NP_001068847.1
Rattus norvegicus (Norway rat)	Cuta	NP_997659.2
Danio rerio (zebrafish)	LOC100535353	XP_003201685.2
Pan troglodytes (chimpanzee)	CUTA	XP_003311267.1
	CUTA	XP_001116293.1
Xenopus tropicalis (tropical clawed frog)	cuta	NP_001165769.1
Homo sapiens (human)	CUTA	NP_001014840.1
Mus musculus (house mouse)	Cuta	NP_080583.3

Gene Ontology
Bibliography

Related articles in PubMed

Role of copper and the copper-related protein CUTA in mediating APP processing and A? generation.
Hou P, Liu G, Zhao Y, Shi Z, Zheng Q, Bu G, Xu H, Zhang YW
Neurobiology of aging36(3)1310-5(2015 Mar)

Unusual transfer of CutA into the secretory pathway, evidenced by fusion proteins with acetylcholinesterase.
Liang D, Carvalho S, Bon S, Massouli? J
The FEBS journal276(16)4473-82(2009 Aug)

Protein CutA undergoes an unusual transfer into the secretory pathway and affects the folding, oligomerization, and secretion of acetylcholinesterase.
Liang D, Nunes-Tavares N, Xie HQ, Carvalho S, Bon S, Massouli? J
The Journal of biological chemistry284(8)5195-207(2009 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

an N-terminal CutA domain actually drives AChE into the endoplasmic reticulum and allows its secretion
Title: Unusual transfer of CutA into the secretory pathway, evidenced by fusion proteins with acetylcholinesterase.

The following Cuta gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cuta cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu01965	NM_026307.3 Latest version!	Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu03328	NM_026948.3 Latest version!	Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu53958	XM_006524832.4 Latest version!	Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu87257	XM_030250013.1 Latest version!	Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu53958	XM_006524832.3	Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cuta ( XM_006524832.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006524895.1 Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu53958
Clone ID Related Accession (Same CDS sequence)	XM_006524832.3 , XM_006524832.4
Accession Version	XM_006524832.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 315bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	protein CutA isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006524832.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACTGGG GGCGGGCGCC CGGCGTCTTG CTCGGCGGAG GGGCCACTCT GCTCCTGTCG 
TTTCTTTGGA TGCCAGCGCT ACTGCCGGTG GCTTCCCGCC TTCTGTTGCT ACCCCGAGCT 
CTGCTGTCAA TGGCTTCTGG AAGCCCTCCG TCCCAGCCCC CTCCGGCCTC GGGCTCCGGC 
TACGTTCCAG GATCAGTCTC TGCAGCCTTT GTCACTTGTC CCAACGAAAA AGTCGCCAAG 
GAGATCGCCA GGGCAGTGGT AGAGAAGCGT CTGGCAGCCT GCGTCAACCT CATCCCGCAG 
ATCACATCCA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006524895.1
CDS	381..695
Translation	MNWGRAPGVLLGGGATLLLSFLWMPALLPVASRLLLLPRALLSMASGSPPSQPPPASGSGYVPGSVSAAFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSI

Target ORF information:

RefSeq Version	XM_006524832.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006524832.3

ORF Insert Sequence:

ATGAACTGGG GGCGGGCGCC CGGCGTCTTG CTCGGCGGAG GGGCCACTCT GCTCCTGTCG 
TTTCTTTGGA TGCCAGCGCT ACTGCCGGTG GCTTCCCGCC TTCTGTTGCT ACCCCGAGCT 
CTGCTGTCAA TGGCTTCTGG AAGCCCTCCG TCCCAGCCCC CTCCGGCCTC GGGCTCCGGC 
TACGTTCCAG GATCAGTCTC TGCAGCCTTT GTCACTTGTC CCAACGAAAA AGTCGCCAAG 
GAGATCGCCA GGGCAGTGGT AGAGAAGCGT CTGGCAGCCT GCGTCAACCT CATCCCGCAG 
ATCACATCCA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cuta ( NM_026307.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080583.3 Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu01965
Clone ID Related Accession (Same CDS sequence)	NM_026307.3
Accession Version	NM_026307.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 534bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	protein CutA isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AA197830.1, AK002828.1 and CA323205.1. On Nov 7, 2013 this sequence version replaced NM_026307.2. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BY703910.1, BY703330.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGAACTGGG GGCGGGCGCC CGGCGTCTTG CTCGGCGGAG GGGCCACTCT GCTCCTGTCG 
TTTCTTTGGA TGCCAGCGCT ACTGCCGGTG GCTTCCCGCC TTCTGTTGCT ACCCCGAGCT 
CTGCTGTCAA TGGCTTCTGG AAGCCCTCCG TCCCAGCCCC CTCCGGCCTC GGGCTCCGGC 
TACGTTCCAG GATCAGTCTC TGCAGCCTTT GTCACTTGTC CCAACGAAAA AGTCGCCAAG 
GAGATCGCCA GGGCAGTGGT AGAGAAGCGT CTGGCAGCCT GCGTCAACCT CATCCCGCAG 
ATCACATCCA TCTATGAATG GAAAGGAAAG ATCGAGGAAG ATAGTGAGGT GCTGATGATG 
ATTAAAACCC AAAGCTCCCT GGTCCCTGCT CTGACAGAGT TTGTTCGATC TGTGCACCCT 
TATGAAGTGG CCGAAGTGAT TGCACTGCCT GTGGAGCAGG GAAATCCCCC GTACCTGCAC 
TGGGTGCACC AGGTCACAGA ATCGGTTTCA AATTCTGGCA CAGCCCTACC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080583.3
CDS	99..632
Translation	MNWGRAPGVLLGGGATLLLSFLWMPALLPVASRLLLLPRALLSMASGSPPSQPPPASGSGYVPGSVSAAFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSIYEWKGKIEEDSEVLMMIKTQSSLVPALTEFVRSVHPYEVAEVIALPVEQGNPPYLHWVHQVTESVSNSGTALP

Target ORF information:

RefSeq Version	NM_026307.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026307.3

ORF Insert Sequence:

ATGAACTGGG GGCGGGCGCC CGGCGTCTTG CTCGGCGGAG GGGCCACTCT GCTCCTGTCG 
TTTCTTTGGA TGCCAGCGCT ACTGCCGGTG GCTTCCCGCC TTCTGTTGCT ACCCCGAGCT 
CTGCTGTCAA TGGCTTCTGG AAGCCCTCCG TCCCAGCCCC CTCCGGCCTC GGGCTCCGGC 
TACGTTCCAG GATCAGTCTC TGCAGCCTTT GTCACTTGTC CCAACGAAAA AGTCGCCAAG 
GAGATCGCCA GGGCAGTGGT AGAGAAGCGT CTGGCAGCCT GCGTCAACCT CATCCCGCAG 
ATCACATCCA TCTATGAATG GAAAGGAAAG ATCGAGGAAG ATAGTGAGGT GCTGATGATG 
ATTAAAACCC AAAGCTCCCT GGTCCCTGCT CTGACAGAGT TTGTTCGATC TGTGCACCCT 
TATGAAGTGG CCGAAGTGAT TGCACTGCCT GTGGAGCAGG GAAATCCCCC GTACCTGCAC 
TGGGTGCACC AGGTCACAGA ATCGGTTTCA AATTCTGGCA CAGCCCTACC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cuta ( NM_026948.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081224.1 Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu03328
Clone ID Related Accession (Same CDS sequence)	NM_026948.3
Accession Version	NM_026948.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Mus musculus(house mouse)
Product	protein CutA isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AA197830.1, AK003381.1 and CA323205.1. On Nov 7, 2013 this sequence version replaced NM_026948.2. Transcript Variant: This variant (2) lacks an internal exon in the 5' region, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: CA323205.1, AK003381.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGCCAGCGC TACTGCCGGT GGCTTCCCGC CTTCTGTTGC TACCCCGAGC TCTGCTGTCA 
ATGGCTTCTG GAAGCCCTCC GTCCCAGCCC CCTCCGGCCT CGGGCTCCGG CTACGTTCCA 
GGATCAGTCT CTGCAGCCTT TGTCACTTGT CCCAACGAAA AAGTCGCCAA GGAGATCGCC 
AGGGCAGTGG TAGAGAAGCG TCTGGCAGCC TGCGTCAACC TCATCCCGCA GATCACATCC 
ATCTATGAAT GGAAAGGAAA GATCGAGGAA GATAGTGAGG TGCTGATGAT GATTAAAACC 
CAAAGCTCCC TGGTCCCTGC TCTGACAGAG TTTGTTCGAT CTGTGCACCC TTATGAAGTG 
GCCGAAGTGA TTGCACTGCC TGTGGAGCAG GGAAATCCCC CGTACCTGCA CTGGGTGCAC 
CAGGTCACAG AATCGGTTTC AAATTCTGGC ACAGCCCTAC CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081224.1
CDS	116..580
Translation	MPALLPVASRLLLLPRALLSMASGSPPSQPPPASGSGYVPGSVSAAFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSIYEWKGKIEEDSEVLMMIKTQSSLVPALTEFVRSVHPYEVAEVIALPVEQGNPPYLHWVHQVTESVSNSGTALP

Target ORF information:

RefSeq Version	NM_026948.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026948.3

ORF Insert Sequence:

ATGCCAGCGC TACTGCCGGT GGCTTCCCGC CTTCTGTTGC TACCCCGAGC TCTGCTGTCA 
ATGGCTTCTG GAAGCCCTCC GTCCCAGCCC CCTCCGGCCT CGGGCTCCGG CTACGTTCCA 
GGATCAGTCT CTGCAGCCTT TGTCACTTGT CCCAACGAAA AAGTCGCCAA GGAGATCGCC 
AGGGCAGTGG TAGAGAAGCG TCTGGCAGCC TGCGTCAACC TCATCCCGCA GATCACATCC 
ATCTATGAAT GGAAAGGAAA GATCGAGGAA GATAGTGAGG TGCTGATGAT GATTAAAACC 
CAAAGCTCCC TGGTCCCTGC TCTGACAGAG TTTGTTCGAT CTGTGCACCC TTATGAAGTG 
GCCGAAGTGA TTGCACTGCC TGTGGAGCAG GGAAATCCCC CGTACCTGCA CTGGGTGCAC 
CAGGTCACAG AATCGGTTTC AAATTCTGGC ACAGCCCTAC CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cuta ( XM_006524832.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006524895.1 Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu53958
Clone ID Related Accession (Same CDS sequence)	XM_006524832.3 , XM_006524832.4
Accession Version	XM_006524832.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 315bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	protein CutA isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006524832.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACTGGG GGCGGGCGCC CGGCGTCTTG CTCGGCGGAG GGGCCACTCT GCTCCTGTCG 
TTTCTTTGGA TGCCAGCGCT ACTGCCGGTG GCTTCCCGCC TTCTGTTGCT ACCCCGAGCT 
CTGCTGTCAA TGGCTTCTGG AAGCCCTCCG TCCCAGCCCC CTCCGGCCTC GGGCTCCGGC 
TACGTTCCAG GATCAGTCTC TGCAGCCTTT GTCACTTGTC CCAACGAAAA AGTCGCCAAG 
GAGATCGCCA GGGCAGTGGT AGAGAAGCGT CTGGCAGCCT GCGTCAACCT CATCCCGCAG 
ATCACATCCA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006524895.1
CDS	272..586
Translation	MNWGRAPGVLLGGGATLLLSFLWMPALLPVASRLLLLPRALLSMASGSPPSQPPPASGSGYVPGSVSAAFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSI

Target ORF information:

RefSeq Version	XM_006524832.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006524832.4

ORF Insert Sequence:

ATGAACTGGG GGCGGGCGCC CGGCGTCTTG CTCGGCGGAG GGGCCACTCT GCTCCTGTCG 
TTTCTTTGGA TGCCAGCGCT ACTGCCGGTG GCTTCCCGCC TTCTGTTGCT ACCCCGAGCT 
CTGCTGTCAA TGGCTTCTGG AAGCCCTCCG TCCCAGCCCC CTCCGGCCTC GGGCTCCGGC 
TACGTTCCAG GATCAGTCTC TGCAGCCTTT GTCACTTGTC CCAACGAAAA AGTCGCCAAG 
GAGATCGCCA GGGCAGTGGT AGAGAAGCGT CTGGCAGCCT GCGTCAACCT CATCCCGCAG 
ATCACATCCA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cuta ( XM_030250013.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030105873.1 Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu87257
Clone ID Related Accession (Same CDS sequence)	XM_030250013.1
Accession Version	XM_030250013.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	protein CutA isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCGGGC CGCTGGGGCG CACGACCTCA GATAAAGCTG CCGATTGGTC GGAGGGCTCG 
ACGCCACGCC CACTTAAGAG GGCGGGGCTA CCGGGCCACT TGAGGGCCGG GATTGGCCAG 
GTCTGGAGAC TCCGGGAAGG CAGGGCTGCT CCTGTCACGT GGTGCACACT GTTTTCGCGT 
CACGTGGCTA CTGCAGGCCA CTCTGCTCCT GTCGTTTCTT TGGATGCCAG CGCTACTGCC 
GGTGGCTTCC CGCCTTCTGT TGCTACCCCG AGCTCTGCTG TCAATGGCTT CTGGAAGCCC 
TCCGTCCCAG CCCCCTCCGG CCTCGGGCTC CGGCTACGTT CCAGGATCAG TCTCTGCAGC 
CTTTGTCACT TGTCCCAACG AAAAAGTCGC CAAGGAGATC GCCAGGGCAG TGGTAGAGAA 
GCGTCTGGCA GCCTGCGTCA ACCTCATCCC GCAGATCACA TCCATACTTT GTTCCCTTCT 
TTCTCTGACC TCTTCAGCTA TGAATGGAAA GGAAAGATCG AGGAAGATAG TGAGGTGCTG 
ATGATGATTA AAACCCAAAG CTCCCTGGTC CCTGCTCTGA CAGAGTTTGT TCGATCTGTG 
CACCCTTATG AAGTGGCCGA AGTGATTGCA CTGCCTGTGG AGCAGGGAAA TCCCCCGTAC 
CTGCACTGGG TGCACCAGGT CACAGAATCG GTTTCAAATT CTGGCACAGC CCTACCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030105873.1
CDS	239..958
Translation	MGGPLGRTTSDKAADWSEGSTPRPLKRAGLPGHLRAGIGQVWRLREGRAAPVTWCTLFSRHVATAGHSAPVVSLDASATAGGFPPSVATPSSAVNGFWKPSVPAPSGLGLRLRSRISLCSLCHLSQRKSRQGDRQGSGREASGSLRQPHPADHIHTLFPSFSDLFSYEWKGKIEEDSEVLMMIKTQSSLVPALTEFVRSVHPYEVAEVIALPVEQGNPPYLHWVHQVTESVSNSGTALP

Target ORF information:

RefSeq Version	XM_030250013.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cutA divalent cation tolerance homolog (Cuta), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030250013.1

ORF Insert Sequence:

ATGGGCGGGC CGCTGGGGCG CACGACCTCA GATAAAGCTG CCGATTGGTC GGAGGGCTCG 
ACGCCACGCC CACTTAAGAG GGCGGGGCTA CCGGGCCACT TGAGGGCCGG GATTGGCCAG 
GTCTGGAGAC TCCGGGAAGG CAGGGCTGCT CCTGTCACGT GGTGCACACT GTTTTCGCGT 
CACGTGGCTA CTGCAGGCCA CTCTGCTCCT GTCGTTTCTT TGGATGCCAG CGCTACTGCC 
GGTGGCTTCC CGCCTTCTGT TGCTACCCCG AGCTCTGCTG TCAATGGCTT CTGGAAGCCC 
TCCGTCCCAG CCCCCTCCGG CCTCGGGCTC CGGCTACGTT CCAGGATCAG TCTCTGCAGC 
CTTTGTCACT TGTCCCAACG AAAAAGTCGC CAAGGAGATC GCCAGGGCAG TGGTAGAGAA 
GCGTCTGGCA GCCTGCGTCA ACCTCATCCC GCAGATCACA TCCATACTTT GTTCCCTTCT 
TTCTCTGACC TCTTCAGCTA TGAATGGAAA GGAAAGATCG AGGAAGATAG TGAGGTGCTG 
ATGATGATTA AAACCCAAAG CTCCCTGGTC CCTGCTCTGA CAGAGTTTGT TCGATCTGTG 
CACCCTTATG AAGTGGCCGA AGTGATTGCA CTGCCTGTGG AGCAGGGAAA TCCCCCGTAC 
CTGCACTGGG TGCACCAGGT CACAGAATCG GTTTCAAATT CTGGCACAGC CCTACCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of copper and the copper-related protein CUTA in mediating APP processing and A? generation.
Neurobiology of aging36(3)1310-5(2015 Mar)
Hou P,Liu G,Zhao Y,Shi Z,Zheng Q,Bu G,Xu H,Zhang YW

Unusual transfer of CutA into the secretory pathway, evidenced by fusion proteins with acetylcholinesterase.
The FEBS journal276(16)4473-82(2009 Aug)
Liang D,Carvalho S,Bon S,Massouli? J

Protein CutA undergoes an unusual transfer into the secretory pathway and affects the folding, oligomerization, and secretion of acetylcholinesterase.
The Journal of biological chemistry284(8)5195-207(2009 Feb)
Liang D,Nunes-Tavares N,Xie HQ,Carvalho S,Bon S,Massouli? J