Moap1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Moap1
Entrez Gene ID	64113
Full Name	modulator of apoptosis 1
Synonyms	AA987038,Map-1,Pnma4
General protein information	Preferred Names modulator of apoptosis 1 Names modulator of apoptosis 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12\|12 E

mRNA and Protein(s)

mRNA	Protein	Name
NM_001142937.2	NP_001136409.1	modulator of apoptosis 1
NM_022323.7	NP_071718.1	modulator of apoptosis 1

Pathways from BioSystems

Homologies

	MOAP1	XP_001089203.1
Homo sapiens (human)	MOAP1	NP_071434.2
Mus musculus (house mouse)	Moap1	NP_071718.1
	PNMA2	XP_001089776.1
Rattus norvegicus (Norway rat)	Moap1	NP_001013119.1
Pan troglodytes (chimpanzee)	MOAP1	XP_510137.2

Gene Ontology
Bibliography

Related articles in PubMed

MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria.
Tan CT, Zhou QL, Su YC, Fu NY, Chang HC, Tao RN, Sukumaran SK, Baksh S, Tan YJ, Sabapathy K, Yu CD, Yu VC
Cell reports16(1)174-185(2016 06)

MAP-1 is a mitochondrial effector of Bax.
Tan KO, Fu NY, Sukumaran SK, Chan SL, Kang JH, Poon KL, Chen BS, Yu VC
Proceedings of the National Academy of Sciences of the United States of America102(41)14623-8(2005 Oct)

MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains.
Tan KO, Tan KM, Chan SL, Yee KS, Bevort M, Ang KC, Yu VC
The Journal of biological chemistry276(4)2802-7(2001 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings reveal a role for MOAP-1 in Fas signaling in the liver by promoting MTCH2-mediated tBid recruitment to mitochondria.
Title: MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria.

MAP-1 is a direct mitochondrial target of Bax.
Title: MAP-1 is a mitochondrial effector of Bax.

The following Moap1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Moap1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06642	NM_022323.7 Latest version!	Mus musculus modulator of apoptosis 1 (Moap1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu06642	NM_001142937.2 Latest version!	Mus musculus modulator of apoptosis 1 (Moap1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Moap1 ( NM_001142937.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001136409.1 Mus musculus modulator of apoptosis 1 (Moap1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu06642
Clone ID Related Accession (Same CDS sequence)	NM_001142937.2 , NM_022323.7
Accession Version	NM_001142937.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-22
Organism	Mus musculus(house mouse)
Product	modulator of apoptosis 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC132315.4 and AU080670.1. On Dec 23, 2011 this sequence version replaced NM_001142937.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660811.81446.1, AU079815.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACACTGA GACTTCTAGA AGACTGGTGC AGAGGGATGG ATATGAATCC TCGGAAAGCA 
CTATTGGTTG CCGGCATCCC TCCGACCTGC GGAGTGGCAG ACATAGAGGA GGCCCTGCAG 
GCTGGCCTTG CTCCCTTAGG GGAACACAGA CTGCTTGGGA GGATGTTCAG GAGGGATGAG 
AACAAGAATG TAGCCCTGAT TGGGCTTACA GTAGAGACTG GCAGTGCCCT GGTCCCCAAG 
GAAATACCTG CAAAAGGAGG TGTCTGGAGA GTGATCTTTA AGCCTCCTGA TACTGATAGT 
GACTTTTTGT GCAGATTAAA TGAGTTTTTA AAGGGGGAGG GCATGACGAT GGGTGAATTA 
ACCAGAGTTC TTGGGAATCG GAATGACCCT CTCGGCCTAG ACCCGGGCAT AATGATCCCT 
GAAATTCGAG CACCCATGTT AGCACAGGCA TTAAATGAGG CCCTTAAGCC TACCCTGCAG 
TATCTGAGGT ACAAAAAGCT GAGTGTGTTC TCAGGCAGGG ATCCTCCAGG ACCAGGTGAG 
GAAGAATTTG AATCTTGGAT GTTTCATACT TCCCAAGTAA TGAAAACATG GCAGGTGTCA 
GATGTAGAGA AAAGAAGGCG GTTGATAGAG AGCCTTAGAG GTCCAGCATT TGAAATTATT 
CGAGTCCTCA AGATAAACAA CCCCTTCATT ACAGTTGCAG AATGCCTGAA GACGCTTGAG 
ACAATATTTG GGATTATTGA TAATCCTAGA GCATTGCAGG TCAAATACCT TACTACTTAT 
CAGAAGACTG ATGAAAAGCT GTCTGCCTAT GTTCTAAGGT TGGAGCCTTT ATTGCAGAAA 
CTGGTTCAGA AAGGAGCAAT TGAGAAAGAA GTTGTGAATC AGGCCCGTCT AGACCAAGTC 
ATTGCTGGGG CAGTCCACAA ATCAGTTCGA AGAGAGCTTG GGCTGCCGGA GGGTAGCCCA 
GCCCCAGGCT TACTGCAGTT GCTGACACTG ATAAAAGATA AGGAGGCCGA AGAAGAAGAG 
GTCCTCCTTC AGGCCGAATT AGAAGGCTAT TGCACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001136409.1
CDS	226..1284
Translation	MTLRLLEDWCRGMDMNPRKALLVAGIPPTCGVADIEEALQAGLAPLGEHRLLGRMFRRDENKNVALIGLTVETGSALVPKEIPAKGGVWRVIFKPPDTDSDFLCRLNEFLKGEGMTMGELTRVLGNRNDPLGLDPGIMIPEIRAPMLAQALNEALKPTLQYLRYKKLSVFSGRDPPGPGEEEFESWMFHTSQVMKTWQVSDVEKRRRLIESLRGPAFEIIRVLKINNPFITVAECLKTLETIFGIIDNPRALQVKYLTTYQKTDEKLSAYVLRLEPLLQKLVQKGAIEKEVVNQARLDQVIAGAVHKSVRRELGLPEGSPAPGLLQLLTLIKDKEAEEEEVLLQAELEGYCT

Target ORF information:

RefSeq Version	NM_001142937.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus modulator of apoptosis 1 (Moap1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142937.2

ORF Insert Sequence:

ATGACACTGA GACTTCTAGA AGACTGGTGC AGAGGGATGG ATATGAATCC TCGGAAAGCA 
CTATTGGTTG CCGGCATCCC TCCGACCTGC GGAGTGGCAG ACATAGAGGA GGCCCTGCAG 
GCTGGCCTTG CTCCCTTAGG GGAACACAGA CTGCTTGGGA GGATGTTCAG GAGGGATGAG 
AACAAGAATG TAGCCCTGAT TGGGCTTACA GTAGAGACTG GCAGTGCCCT GGTCCCCAAG 
GAAATACCTG CAAAAGGAGG TGTCTGGAGA GTGATCTTTA AGCCTCCTGA TACTGATAGT 
GACTTTTTGT GCAGATTAAA TGAGTTTTTA AAGGGGGAGG GCATGACGAT GGGTGAATTA 
ACCAGAGTTC TTGGGAATCG GAATGACCCT CTCGGCCTAG ACCCGGGCAT AATGATCCCT 
GAAATTCGAG CACCCATGTT AGCACAGGCA TTAAATGAGG CCCTTAAGCC TACCCTGCAG 
TATCTGAGGT ACAAAAAGCT GAGTGTGTTC TCAGGCAGGG ATCCTCCAGG ACCAGGTGAG 
GAAGAATTTG AATCTTGGAT GTTTCATACT TCCCAAGTAA TGAAAACATG GCAGGTGTCA 
GATGTAGAGA AAAGAAGGCG GTTGATAGAG AGCCTTAGAG GTCCAGCATT TGAAATTATT 
CGAGTCCTCA AGATAAACAA CCCCTTCATT ACAGTTGCAG AATGCCTGAA GACGCTTGAG 
ACAATATTTG GGATTATTGA TAATCCTAGA GCATTGCAGG TCAAATACCT TACTACTTAT 
CAGAAGACTG ATGAAAAGCT GTCTGCCTAT GTTCTAAGGT TGGAGCCTTT ATTGCAGAAA 
CTGGTTCAGA AAGGAGCAAT TGAGAAAGAA GTTGTGAATC AGGCCCGTCT AGACCAAGTC 
ATTGCTGGGG CAGTCCACAA ATCAGTTCGA AGAGAGCTTG GGCTGCCGGA GGGTAGCCCA 
GCCCCAGGCT TACTGCAGTT GCTGACACTG ATAAAAGATA AGGAGGCCGA AGAAGAAGAG 
GTCCTCCTTC AGGCCGAATT AGAAGGCTAT TGCACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Moap1 ( NM_022323.7 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_071718.1 Mus musculus modulator of apoptosis 1 (Moap1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu06642
Clone ID Related Accession (Same CDS sequence)	NM_001142937.2 , NM_022323.7
Accession Version	NM_022323.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-22
Organism	Mus musculus(house mouse)
Product	modulator of apoptosis 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC132315.4 and BU614788.1. On Dec 23, 2011 this sequence version replaced NM_022323.6. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.267432.1, BU614788.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACACTGA GACTTCTAGA AGACTGGTGC AGAGGGATGG ATATGAATCC TCGGAAAGCA 
CTATTGGTTG CCGGCATCCC TCCGACCTGC GGAGTGGCAG ACATAGAGGA GGCCCTGCAG 
GCTGGCCTTG CTCCCTTAGG GGAACACAGA CTGCTTGGGA GGATGTTCAG GAGGGATGAG 
AACAAGAATG TAGCCCTGAT TGGGCTTACA GTAGAGACTG GCAGTGCCCT GGTCCCCAAG 
GAAATACCTG CAAAAGGAGG TGTCTGGAGA GTGATCTTTA AGCCTCCTGA TACTGATAGT 
GACTTTTTGT GCAGATTAAA TGAGTTTTTA AAGGGGGAGG GCATGACGAT GGGTGAATTA 
ACCAGAGTTC TTGGGAATCG GAATGACCCT CTCGGCCTAG ACCCGGGCAT AATGATCCCT 
GAAATTCGAG CACCCATGTT AGCACAGGCA TTAAATGAGG CCCTTAAGCC TACCCTGCAG 
TATCTGAGGT ACAAAAAGCT GAGTGTGTTC TCAGGCAGGG ATCCTCCAGG ACCAGGTGAG 
GAAGAATTTG AATCTTGGAT GTTTCATACT TCCCAAGTAA TGAAAACATG GCAGGTGTCA 
GATGTAGAGA AAAGAAGGCG GTTGATAGAG AGCCTTAGAG GTCCAGCATT TGAAATTATT 
CGAGTCCTCA AGATAAACAA CCCCTTCATT ACAGTTGCAG AATGCCTGAA GACGCTTGAG 
ACAATATTTG GGATTATTGA TAATCCTAGA GCATTGCAGG TCAAATACCT TACTACTTAT 
CAGAAGACTG ATGAAAAGCT GTCTGCCTAT GTTCTAAGGT TGGAGCCTTT ATTGCAGAAA 
CTGGTTCAGA AAGGAGCAAT TGAGAAAGAA GTTGTGAATC AGGCCCGTCT AGACCAAGTC 
ATTGCTGGGG CAGTCCACAA ATCAGTTCGA AGAGAGCTTG GGCTGCCGGA GGGTAGCCCA 
GCCCCAGGCT TACTGCAGTT GCTGACACTG ATAAAAGATA AGGAGGCCGA AGAAGAAGAG 
GTCCTCCTTC AGGCCGAATT AGAAGGCTAT TGCACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071718.1
CDS	270..1328
Translation	MTLRLLEDWCRGMDMNPRKALLVAGIPPTCGVADIEEALQAGLAPLGEHRLLGRMFRRDENKNVALIGLTVETGSALVPKEIPAKGGVWRVIFKPPDTDSDFLCRLNEFLKGEGMTMGELTRVLGNRNDPLGLDPGIMIPEIRAPMLAQALNEALKPTLQYLRYKKLSVFSGRDPPGPGEEEFESWMFHTSQVMKTWQVSDVEKRRRLIESLRGPAFEIIRVLKINNPFITVAECLKTLETIFGIIDNPRALQVKYLTTYQKTDEKLSAYVLRLEPLLQKLVQKGAIEKEVVNQARLDQVIAGAVHKSVRRELGLPEGSPAPGLLQLLTLIKDKEAEEEEVLLQAELEGYCT

Target ORF information:

RefSeq Version	NM_022323.7
Organism	Mus musculus(house mouse)
Definition	Mus musculus modulator of apoptosis 1 (Moap1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022323.7

ORF Insert Sequence:

ATGACACTGA GACTTCTAGA AGACTGGTGC AGAGGGATGG ATATGAATCC TCGGAAAGCA 
CTATTGGTTG CCGGCATCCC TCCGACCTGC GGAGTGGCAG ACATAGAGGA GGCCCTGCAG 
GCTGGCCTTG CTCCCTTAGG GGAACACAGA CTGCTTGGGA GGATGTTCAG GAGGGATGAG 
AACAAGAATG TAGCCCTGAT TGGGCTTACA GTAGAGACTG GCAGTGCCCT GGTCCCCAAG 
GAAATACCTG CAAAAGGAGG TGTCTGGAGA GTGATCTTTA AGCCTCCTGA TACTGATAGT 
GACTTTTTGT GCAGATTAAA TGAGTTTTTA AAGGGGGAGG GCATGACGAT GGGTGAATTA 
ACCAGAGTTC TTGGGAATCG GAATGACCCT CTCGGCCTAG ACCCGGGCAT AATGATCCCT 
GAAATTCGAG CACCCATGTT AGCACAGGCA TTAAATGAGG CCCTTAAGCC TACCCTGCAG 
TATCTGAGGT ACAAAAAGCT GAGTGTGTTC TCAGGCAGGG ATCCTCCAGG ACCAGGTGAG 
GAAGAATTTG AATCTTGGAT GTTTCATACT TCCCAAGTAA TGAAAACATG GCAGGTGTCA 
GATGTAGAGA AAAGAAGGCG GTTGATAGAG AGCCTTAGAG GTCCAGCATT TGAAATTATT 
CGAGTCCTCA AGATAAACAA CCCCTTCATT ACAGTTGCAG AATGCCTGAA GACGCTTGAG 
ACAATATTTG GGATTATTGA TAATCCTAGA GCATTGCAGG TCAAATACCT TACTACTTAT 
CAGAAGACTG ATGAAAAGCT GTCTGCCTAT GTTCTAAGGT TGGAGCCTTT ATTGCAGAAA 
CTGGTTCAGA AAGGAGCAAT TGAGAAAGAA GTTGTGAATC AGGCCCGTCT AGACCAAGTC 
ATTGCTGGGG CAGTCCACAA ATCAGTTCGA AGAGAGCTTG GGCTGCCGGA GGGTAGCCCA 
GCCCCAGGCT TACTGCAGTT GCTGACACTG ATAAAAGATA AGGAGGCCGA AGAAGAAGAG 
GTCCTCCTTC AGGCCGAATT AGAAGGCTAT TGCACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria.
Cell reports16(1)174-185(2016 06)
Tan CT,Zhou QL,Su YC,Fu NY,Chang HC,Tao RN,Sukumaran SK,Baksh S,Tan YJ,Sabapathy K,Yu CD,Yu VC

MAP-1 is a mitochondrial effector of Bax.
Proceedings of the National Academy of Sciences of the United States of America102(41)14623-8(2005 Oct)
Tan KO,Fu NY,Sukumaran SK,Chan SL,Kang JH,Poon KL,Chen BS,Yu VC

MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains.
The Journal of biological chemistry276(4)2802-7(2001 Jan)
Tan KO,Tan KM,Chan SL,Yee KS,Bevort M,Ang KC,Yu VC