Zc4h2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Zc4h2
Entrez Gene ID	245522
Full Name	zinc finger, C4H2 domain containing
Synonyms	Gm372,mKIAA1166
General protein information	Preferred Names zinc finger, C4H2 domain containing Names zinc finger C4H2 domain-containing protein hepatocellular carcinoma-associated antigen 127 homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X\|X C3

mRNA and Protein(s)

mRNA	Protein	Name
XM_011247587.3	XP_011245889.1	zinc finger C4H2 domain-containing protein isoform X1
NM_001289696.1	NP_001276625.1	zinc finger C4H2 domain-containing protein isoform 2
XM_011247587.2	XP_011245889.1	zinc finger C4H2 domain-containing protein isoform X1
NM_001289697.1	NP_001276626.1	zinc finger C4H2 domain-containing protein isoform 3
NM_001003916.2	NP_001003916.1	zinc finger C4H2 domain-containing protein isoform 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Zc4h2	NP_001119846.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010728	XP_311442.3
Xenopus tropicalis (tropical clawed frog)	zc4h2	NP_001016675.1
	ZC4H2	XP_001098245.1
Bos taurus (cattle)	ZC4H2	NP_001071579.1
Homo sapiens (human)	ZC4H2	NP_061154.1
Canis lupus familiaris (dog)	ZC4H2	XP_549040.3
Mus musculus (house mouse)	Zc4h2	NP_001003916.1
Gallus gallus (chicken)	ZC4H2	XP_420173.3
Danio rerio (zebrafish)	zc4h2	NP_955936.1
Pan troglodytes (chimpanzee)	ZC4H2	XP_521094.1
Drosophila melanogaster (fruit fly)	CG13001	NP_573181.1

Gene Ontology
Bibliography

Related articles in PubMed

ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in
Ma P, Ren B, Yang X, Sun B, Liu X, Kong Q, Li C, Mao B
Open biology7(8)(2017 Aug)

ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity.
Hirata H, Nanda I, van Riesen A, McMichael G, Hu H, Hambrock M, Papon MA, Fischer U, Marouillat S, Ding C, Alirol S, Bienek M, Preisler-Adams S, Grimme A, Seelow D, Webster R, Haan E, MacLennan A, Stenzel W, Yap TY, Gardner A, Nguyen LS, Shaw M, Lebrun N, Haas SA, Kress W, Haaf T, Schellenberger E, Chelly J, Viot G, Shaffer LG, Rosenfeld JA, Kramer N, Falk R, El-Khechen D, Escobar LF, Hennekam R, Wieacker P, H?bner C, Ropers HH, Gecz J, Schuelke M, Laumonnier F, Kalscheuer VM
American journal of human genetics92(5)681-95(2013 May)

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Okazaki N, Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S, Saga Y, Nagase T, Ohara O, Koga H
DNA research : an international journal for rapid publication of reports on genes and genomes10(4)167-80(2003 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In mouse primary hippocampal neurons, transiently produced ZC4H2 localized to the postsynaptic compartment of excitatory synapses, and the altered protein influenced dendritic spine density.
Title: ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity.

The following Zc4h2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Zc4h2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu14019	NM_001289696.1 Latest version!	Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu14137	NM_001289697.1 Latest version!	Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu14048	NM_001003916.2 Latest version!	Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu74229	XM_011247587.3 Latest version!	Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu74229	XM_011247587.2	Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Zc4h2 ( NM_001289696.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001276625.1 Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu14019
Clone ID Related Accession (Same CDS sequence)	NM_001289696.1
Accession Version	NM_001289696.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 591bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Mus musculus(house mouse)
Product	zinc finger C4H2 domain-containing protein isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY200912.1, BC079862.1, AL671982.4 and AI844550.1. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. This results in a shorter isoform (2) that has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC050850.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGGAACAAG 
ACTCTGCAGA TGGAAAAGAT CAAGGCCCGT TTGAAGGCTG AGTTCGAGGC TCTGGAGTCT 
GAAGAGAGGC ACCTGAAAGA ATACAAACAG GAGATGGATC TCCTGCTACA GGAGAAGATG 
GCCCATGTGG AGGAACTCCG ACTCATCCAT GCTGATATCA ATGTGATGGA AAACACCATT 
AAACAGTCTG AAAATGACTT AAACAAGCTG CTGGAGTCAA CCCGGAGGCT TCATGATGAG 
TATAAACCAC TGAAAGAACA CGTGGATGCC CTGCGCATGA CATTGGGCCT GCAAAGGCTT 
CCTGACCTGT GTGAAGAGGA AGAGAAACTC TCCTTGGAAA TGACCCATCC AATGTATGTC 
ATCCCCAAAG TTACTTTGAG AAGCAGAAAG CAGAATGGCA GACTGAACCT CAAGAACCCC 
CCATACCTGA ATCCCTTGCT GCTGCAGCTG CTGCTGCTCA ACAACTCCAG GTGGCCAGGA 
AGCAGGACAC AAGGCAGACA GCCACCTTCA GGCAGCAGCC TCCACCTATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276625.1
CDS	206..796
Translation	MADEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSLEMTHPMYVIPKVTLRSRKQNGRLNLKNPPYLNPLLLQLLLLNNSRWPGSRTQGRQPPSGSSLHL

Target ORF information:

RefSeq Version	NM_001289696.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289696.1

ORF Insert Sequence:

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGGAACAAG 
ACTCTGCAGA TGGAAAAGAT CAAGGCCCGT TTGAAGGCTG AGTTCGAGGC TCTGGAGTCT 
GAAGAGAGGC ACCTGAAAGA ATACAAACAG GAGATGGATC TCCTGCTACA GGAGAAGATG 
GCCCATGTGG AGGAACTCCG ACTCATCCAT GCTGATATCA ATGTGATGGA AAACACCATT 
AAACAGTCTG AAAATGACTT AAACAAGCTG CTGGAGTCAA CCCGGAGGCT TCATGATGAG 
TATAAACCAC TGAAAGAACA CGTGGATGCC CTGCGCATGA CATTGGGCCT GCAAAGGCTT 
CCTGACCTGT GTGAAGAGGA AGAGAAACTC TCCTTGGAAA TGACCCATCC AATGTATGTC 
ATCCCCAAAG TTACTTTGAG AAGCAGAAAG CAGAATGGCA GACTGAACCT CAAGAACCCC 
CCATACCTGA ATCCCTTGCT GCTGCAGCTG CTGCTGCTCA ACAACTCCAG GTGGCCAGGA 
AGCAGGACAC AAGGCAGACA GCCACCTTCA GGCAGCAGCC TCCACCTATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Zc4h2 ( NM_001289697.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001276626.1 Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu14137
Clone ID Related Accession (Same CDS sequence)	NM_001289697.1
Accession Version	NM_001289697.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Mus musculus(house mouse)
Product	zinc finger C4H2 domain-containing protein isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY200912.1, BC079862.1 and AI844550.1. Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter isoform (3), compared to isoform 3. ##Evidence-Data-START## Transcript exon combination :: AK129302.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849382 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGGAACAAG 
ACTCTGCAGA TGGAAAAGAT CAAGGCCCGT TTGAAGGCTG AGTTCGAGGC TCTGGAGTCT 
GAAGAGAGGC ACCTGAAAGA ATACAAACAG GAGATGGATC TCCTGCTACA GGAGAAGATG 
GCCCATGTGG AGGAACTCCG ACTCATCCAT GCTGATATCA ATGTGTCTGA AAATGACTTA 
AACAAGCTGC TGGAGTCAAC CCGGAGGCTT CATGATGAGT ATAAACCACT GAAAGAACAC 
GTGGATGCCC TGCGCATGAC ATTGGGCCTG CAAAGGCTTC CTGACCTGTG TGAAGAGGAA 
GAGAAACTCT CCTTGGATTA CTTTGAGAAG CAGAAAGCAG AATGGCAGAC TGAACCTCAA 
GAACCCCCCA TACCTGAATC CCTTGCTGCT GCAGCTGCTG CTGCTCAACA ACTCCAGGTG 
GCCAGGAAGC AGGACACAAG GCAGACAGCC ACCTTCAGGC AGCAGCCTCC ACCTATGAAG 
GCCTGTTTGT CATGTCACCA ACAGATTCAT CGAAATGCAC CTATATGCCC TCTTTGCAAA 
GCCAAGAGTC GGTCACGGAA CCCCAAAAAG CCAAAACGGA AGCAAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276626.1
CDS	206..859
Translation	MADEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE

Target ORF information:

RefSeq Version	NM_001289697.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289697.1

ORF Insert Sequence:

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGGAACAAG 
ACTCTGCAGA TGGAAAAGAT CAAGGCCCGT TTGAAGGCTG AGTTCGAGGC TCTGGAGTCT 
GAAGAGAGGC ACCTGAAAGA ATACAAACAG GAGATGGATC TCCTGCTACA GGAGAAGATG 
GCCCATGTGG AGGAACTCCG ACTCATCCAT GCTGATATCA ATGTGTCTGA AAATGACTTA 
AACAAGCTGC TGGAGTCAAC CCGGAGGCTT CATGATGAGT ATAAACCACT GAAAGAACAC 
GTGGATGCCC TGCGCATGAC ATTGGGCCTG CAAAGGCTTC CTGACCTGTG TGAAGAGGAA 
GAGAAACTCT CCTTGGATTA CTTTGAGAAG CAGAAAGCAG AATGGCAGAC TGAACCTCAA 
GAACCCCCCA TACCTGAATC CCTTGCTGCT GCAGCTGCTG CTGCTCAACA ACTCCAGGTG 
GCCAGGAAGC AGGACACAAG GCAGACAGCC ACCTTCAGGC AGCAGCCTCC ACCTATGAAG 
GCCTGTTTGT CATGTCACCA ACAGATTCAT CGAAATGCAC CTATATGCCC TCTTTGCAAA 
GCCAAGAGTC GGTCACGGAA CCCCAAAAAG CCAAAACGGA AGCAAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Zc4h2 ( XM_011247587.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011245889.1 Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu74229
Clone ID Related Accession (Same CDS sequence)	XM_011247587.3 , XM_011247587.2
Accession Version	XM_011247587.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	zinc finger C4H2 domain-containing protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011247587.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGAAATTTC 
AGGAACAAGA CTCTGCAGAT GGAAAAGATC AAGGCCCGTT TGAAGGCTGA GTTCGAGGCT 
CTGGAGTCTG AAGAGAGGCA CCTGAAAGAA TACAAACAGG AGATGGATCT CCTGCTACAG 
GAGAAGATGG CCCATGTGGA GGAACTCCGA CTCATCCATG CTGATATCAA TGTGATGGAA 
AACACCATTA AACAGTCTGA AAATGACTTA AACAAGCTGC TGGAGTCAAC CCGGAGGCTT 
CATGATGAGT ATAAACCACT GAAAGAACAC GTGGATGCCC TGCGCATGAC ATTGGGCCTG 
CAAAGGCTTC CTGACCTGTG TGAAGAGGAA GAGAAACTCT CCTTGGATTA CTTTGAGAAG 
CAGAAAGCAG AATGGCAGAC TGAACCTCAA GAACCCCCCA TACCTGAATC CCTTGCTGCT 
GCAGCTGCTG CTGCTCAACA ACTCCAGGTG GCCAGGAAGC AGGACACAAG GCAGACAGCC 
ACCTTCAGGC AGCAGCCTCC ACCTATGAAG GCCTGTTTGT CATGTCACCA ACAGATTCAT 
CGAAATGCAC CTATATGCCC TCTTTGCAAA GCCAAGAGTC GGTCACGGAA CCCCAAAAAG 
CCAAAACGGA AGCAAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011245889.1
CDS	169..852
Translation	MADEQEIMCKLESIKEIRNFRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE

Target ORF information:

RefSeq Version	XM_011247587.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011247587.2

ORF Insert Sequence:

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGAAATTTC 
AGGAACAAGA CTCTGCAGAT GGAAAAGATC AAGGCCCGTT TGAAGGCTGA GTTCGAGGCT 
CTGGAGTCTG AAGAGAGGCA CCTGAAAGAA TACAAACAGG AGATGGATCT CCTGCTACAG 
GAGAAGATGG CCCATGTGGA GGAACTCCGA CTCATCCATG CTGATATCAA TGTGATGGAA 
AACACCATTA AACAGTCTGA AAATGACTTA AACAAGCTGC TGGAGTCAAC CCGGAGGCTT 
CATGATGAGT ATAAACCACT GAAAGAACAC GTGGATGCCC TGCGCATGAC ATTGGGCCTG 
CAAAGGCTTC CTGACCTGTG TGAAGAGGAA GAGAAACTCT CCTTGGATTA CTTTGAGAAG 
CAGAAAGCAG AATGGCAGAC TGAACCTCAA GAACCCCCCA TACCTGAATC CCTTGCTGCT 
GCAGCTGCTG CTGCTCAACA ACTCCAGGTG GCCAGGAAGC AGGACACAAG GCAGACAGCC 
ACCTTCAGGC AGCAGCCTCC ACCTATGAAG GCCTGTTTGT CATGTCACCA ACAGATTCAT 
CGAAATGCAC CTATATGCCC TCTTTGCAAA GCCAAGAGTC GGTCACGGAA CCCCAAAAAG 
CCAAAACGGA AGCAAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Zc4h2 ( NM_001003916.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001003916.1 Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu14048
Clone ID Related Accession (Same CDS sequence)	NM_001003916.2
Accession Version	NM_001003916.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Mus musculus(house mouse)
Product	zinc finger C4H2 domain-containing protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY200912.1, BC079862.1 and AI844550.1. On Jan 25, 2014 this sequence version replaced NM_001003916.1. Transcript Variant: This variant (1) encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK155445.1, BC079862.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGGAACAAG 
ACTCTGCAGA TGGAAAAGAT CAAGGCCCGT TTGAAGGCTG AGTTCGAGGC TCTGGAGTCT 
GAAGAGAGGC ACCTGAAAGA ATACAAACAG GAGATGGATC TCCTGCTACA GGAGAAGATG 
GCCCATGTGG AGGAACTCCG ACTCATCCAT GCTGATATCA ATGTGATGGA AAACACCATT 
AAACAGTCTG AAAATGACTT AAACAAGCTG CTGGAGTCAA CCCGGAGGCT TCATGATGAG 
TATAAACCAC TGAAAGAACA CGTGGATGCC CTGCGCATGA CATTGGGCCT GCAAAGGCTT 
CCTGACCTGT GTGAAGAGGA AGAGAAACTC TCCTTGGATT ACTTTGAGAA GCAGAAAGCA 
GAATGGCAGA CTGAACCTCA AGAACCCCCC ATACCTGAAT CCCTTGCTGC TGCAGCTGCT 
GCTGCTCAAC AACTCCAGGT GGCCAGGAAG CAGGACACAA GGCAGACAGC CACCTTCAGG 
CAGCAGCCTC CACCTATGAA GGCCTGTTTG TCATGTCACC AACAGATTCA TCGAAATGCA 
CCTATATGCC CTCTTTGCAA AGCCAAGAGT CGGTCACGGA ACCCCAAAAA GCCAAAACGG 
AAGCAAGATG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003916.1
CDS	206..880
Translation	MADEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE

Target ORF information:

RefSeq Version	NM_001003916.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003916.2

ORF Insert Sequence:

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGGAACAAG 
ACTCTGCAGA TGGAAAAGAT CAAGGCCCGT TTGAAGGCTG AGTTCGAGGC TCTGGAGTCT 
GAAGAGAGGC ACCTGAAAGA ATACAAACAG GAGATGGATC TCCTGCTACA GGAGAAGATG 
GCCCATGTGG AGGAACTCCG ACTCATCCAT GCTGATATCA ATGTGATGGA AAACACCATT 
AAACAGTCTG AAAATGACTT AAACAAGCTG CTGGAGTCAA CCCGGAGGCT TCATGATGAG 
TATAAACCAC TGAAAGAACA CGTGGATGCC CTGCGCATGA CATTGGGCCT GCAAAGGCTT 
CCTGACCTGT GTGAAGAGGA AGAGAAACTC TCCTTGGATT ACTTTGAGAA GCAGAAAGCA 
GAATGGCAGA CTGAACCTCA AGAACCCCCC ATACCTGAAT CCCTTGCTGC TGCAGCTGCT 
GCTGCTCAAC AACTCCAGGT GGCCAGGAAG CAGGACACAA GGCAGACAGC CACCTTCAGG 
CAGCAGCCTC CACCTATGAA GGCCTGTTTG TCATGTCACC AACAGATTCA TCGAAATGCA 
CCTATATGCC CTCTTTGCAA AGCCAAGAGT CGGTCACGGA ACCCCAAAAA GCCAAAACGG 
AAGCAAGATG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Zc4h2 ( XM_011247587.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011245889.1 Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu74229
Clone ID Related Accession (Same CDS sequence)	XM_011247587.3 , XM_011247587.2
Accession Version	XM_011247587.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	zinc finger C4H2 domain-containing protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011247587.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGAAATTTC 
AGGAACAAGA CTCTGCAGAT GGAAAAGATC AAGGCCCGTT TGAAGGCTGA GTTCGAGGCT 
CTGGAGTCTG AAGAGAGGCA CCTGAAAGAA TACAAACAGG AGATGGATCT CCTGCTACAG 
GAGAAGATGG CCCATGTGGA GGAACTCCGA CTCATCCATG CTGATATCAA TGTGATGGAA 
AACACCATTA AACAGTCTGA AAATGACTTA AACAAGCTGC TGGAGTCAAC CCGGAGGCTT 
CATGATGAGT ATAAACCACT GAAAGAACAC GTGGATGCCC TGCGCATGAC ATTGGGCCTG 
CAAAGGCTTC CTGACCTGTG TGAAGAGGAA GAGAAACTCT CCTTGGATTA CTTTGAGAAG 
CAGAAAGCAG AATGGCAGAC TGAACCTCAA GAACCCCCCA TACCTGAATC CCTTGCTGCT 
GCAGCTGCTG CTGCTCAACA ACTCCAGGTG GCCAGGAAGC AGGACACAAG GCAGACAGCC 
ACCTTCAGGC AGCAGCCTCC ACCTATGAAG GCCTGTTTGT CATGTCACCA ACAGATTCAT 
CGAAATGCAC CTATATGCCC TCTTTGCAAA GCCAAGAGTC GGTCACGGAA CCCCAAAAAG 
CCAAAACGGA AGCAAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011245889.1
CDS	170..853
Translation	MADEQEIMCKLESIKEIRNFRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE

Target ORF information:

RefSeq Version	XM_011247587.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus zinc finger, C4H2 domain containing (Zc4h2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011247587.3

ORF Insert Sequence:

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGAAATTTC 
AGGAACAAGA CTCTGCAGAT GGAAAAGATC AAGGCCCGTT TGAAGGCTGA GTTCGAGGCT 
CTGGAGTCTG AAGAGAGGCA CCTGAAAGAA TACAAACAGG AGATGGATCT CCTGCTACAG 
GAGAAGATGG CCCATGTGGA GGAACTCCGA CTCATCCATG CTGATATCAA TGTGATGGAA 
AACACCATTA AACAGTCTGA AAATGACTTA AACAAGCTGC TGGAGTCAAC CCGGAGGCTT 
CATGATGAGT ATAAACCACT GAAAGAACAC GTGGATGCCC TGCGCATGAC ATTGGGCCTG 
CAAAGGCTTC CTGACCTGTG TGAAGAGGAA GAGAAACTCT CCTTGGATTA CTTTGAGAAG 
CAGAAAGCAG AATGGCAGAC TGAACCTCAA GAACCCCCCA TACCTGAATC CCTTGCTGCT 
GCAGCTGCTG CTGCTCAACA ACTCCAGGTG GCCAGGAAGC AGGACACAAG GCAGACAGCC 
ACCTTCAGGC AGCAGCCTCC ACCTATGAAG GCCTGTTTGT CATGTCACCA ACAGATTCAT 
CGAAATGCAC CTATATGCCC TCTTTGCAAA GCCAAGAGTC GGTCACGGAA CCCCAAAAAG 
CCAAAACGGA AGCAAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in
Open biology7(8)(2017 Aug)
Ma P,Ren B,Yang X,Sun B,Liu X,Kong Q,Li C,Mao B

ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity.
American journal of human genetics92(5)681-95(2013 May)
Hirata H,Nanda I,van Riesen A,McMichael G,Hu H,Hambrock M,Papon MA,Fischer U,Marouillat S,Ding C,Alirol S,Bienek M,Preisler-Adams S,Grimme A,Seelow D,Webster R,Haan E,MacLennan A,Stenzel W,Yap TY,Gardner A,Nguyen LS,Shaw M,Lebrun N,Haas SA,Kress W,Haaf T,Schellenberger E,Chelly J,Viot G,Shaffer LG,Rosenfeld JA,Kramer N,Falk R,El-Khechen D,Escobar LF,Hennekam R,Wieacker P,H?bner C,Ropers HH,Gecz J,Schuelke M,Laumonnier F,Kalscheuer VM

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
DNA research : an international journal for rapid publication of reports on genes and genomes10(4)167-80(2003 Aug)
Okazaki N,Kikuno R,Ohara R,Inamoto S,Koseki H,Hiraoka S,Saga Y,Nagase T,Ohara O,Koga H

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Zc4h2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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