Ssb cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ssb
Entrez Gene ID	20823
Full Name	Sjogren syndrome antigen B
Synonyms	SS-B
General protein information	Preferred Names Sjogren syndrome antigen B Names lupus La protein homolog La protein Lupus LA protein homolog (LA ribonucleoprotein) (LA autoantigen homolog) autoantigen La la autoantigen homolog la ribonucleoprotein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 C2\|2 40.95 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006499069.2	XP_006499132.1	lupus La protein homolog isoform X1
NM_001110145.1	NP_001103615.1	lupus La protein homolog isoform a
NM_009278.4	NP_033304.1	lupus La protein homolog isoform a
NM_001355265.1	NP_001342194.1	lupus La protein homolog isoform b

Pathways from BioSystems

Homologies

	LOC710344	XP_002808052.1
Canis lupus familiaris (dog)	SSB	XP_535952.2
Drosophila melanogaster (fruit fly)	La	NP_477014.1
Xenopus tropicalis (tropical clawed frog)	ssb	NP_001001455.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008952	XP_319705.4
Homo sapiens (human)	SSB	NP_003133.1
Rattus norvegicus (Norway rat)	Ssb	NP_112381.2
Gallus gallus (chicken)	SSB	NP_001180598.1
Danio rerio (zebrafish)	ssb	NP_955841.1
Mus musculus (house mouse)	Ssb	NP_033304.1
Caenorhabditis elegans (roundworm)	C44E4.4	NP_491411.1
Pan troglodytes (chimpanzee)	SSB	XP_001138273.1
Bos taurus (cattle)	SSB	NP_788838.1

Gene Ontology
Bibliography

Related articles in PubMed

La Deletion from Mouse Brain Alters Pre-tRNA Metabolism and Accumulation of Pre-5.8S rRNA, with Neuron Death and Reactive Astrocytosis.
Blewett NH, Iben JR, Gaidamakov S, Maraia RJ
Molecular and cellular biology37(10)(2017 May)

Targeted deletion of the gene encoding the La autoantigen (Sj?gren's syndrome antigen B) in B cells or the frontal brain causes extensive tissue loss.
Gaidamakov S, Maximova OA, Chon H, Blewett NH, Wang H, Crawford AK, Day A, Tulchin N, Crouch RJ, Morse HC 3rd, Blitzer RD, Maraia RJ
Molecular and cellular biology34(1)123-31(2014 Jan)

PDGF enhances IRES-mediated translation of Laminin B1 by cytoplasmic accumulation of La during epithelial to mesenchymal transition.
Petz M, Them NC, Huber H, Mikulits W
Nucleic acids research40(19)9738-49(2012 Oct)

The cellular protein La functions in enhancement of virus release through lipid rafts facilitated by murine leukemia virus glycosylated Gag.
Nitta T, Tam R, Kim JW, Fan H
mBio2(1)e00341-10(2011)

Akt phosphorylation of La regulates specific mRNA translation in glial progenitors.
Brenet F, Socci ND, Sonenberg N, Holland EC
Oncogene28(1)128-39(2009 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

La deletion is associated with Neuron Death and Reactive Astrocytosis.
Title: La Deletion from Mouse Brain Alters Pre-tRNA Metabolism and Accumulation of Pre-5.8S rRNA, with Neuron Death and Reactive Astrocytosis.

Data indicate that La antigen (Sjogren's syndrome antigen B) is essential in different cell types and required for normal development of various tissue types.
Title: Targeted deletion of the gene encoding the La autoantigen (Sj?gren's syndrome antigen B) in B cells or the frontal brain causes extensive tissue loss.

Overexpression of mouse or human La enhanced M-MuLV particle release in the absence of glycosylated gag.
Title: The cellular protein La functions in enhancement of virus release through lipid rafts facilitated by murine leukemia virus glycosylated Gag.

La appears to be an important contributor to Akt-mediated translational regulation of these transcripts in murine glial cells.
Title: Akt phosphorylation of La regulates specific mRNA translation in glial progenitors.

truncation of La alters the immunodominance hierarchy of T cell responsiveness to hLa and may be a factor in the initiation or maintenance of anti-La autoimmunity.
Title: T cell epitopes of the La/SSB autoantigen in humanized transgenic mice expressing the HLA class II haplotype DRB1*0301/DQB1*0201.

The following Ssb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ssb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu30203	NM_001355265.1 Latest version!	Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu30203	XM_006499069.2 Latest version!	Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu15131	NM_001110145.1 Latest version!	Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu15131	NM_009278.4 Latest version!	Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ssb ( NM_001355265.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001342194.1 Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu30203
Clone ID Related Accession (Same CDS sequence)	XM_006499069.2 , NM_001355265.1
Accession Version	NM_001355265.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1245bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Mus musculus(house mouse)
Product	lupus La protein homolog isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL845261.17, BX322634.4 and AL929249.15. On Sep 14, 2017 this sequence version replaced XM_006499069.2. Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice junction in the 3' end compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is 1 aa shorter compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660819.20107.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAA ATGGAGATAA TGAAAAAATG ACTGCTTTGG AGGCCAAAAT CTGTCATCAA 
ATTGAGTATT ATTTTGGAGA CTTCAATTTG CCACGAGACA AGTTTTTAAA AGAACAGATC 
AAATTGGATG AAGGCTGGGT ACCTTTGGAA ACAATGATAA AATTCAACAG GCTAAACCGG 
CTGACAACAG ACTTTAATGT AATTGTGCAA GCACTGAGCA AATCTAAGGC AAAACTCATG 
GAAGTCAGTG CAGACAAAAC TAAAATTAGA AGATCACCAA GCAGACCACT CCCTGAAGTG 
ACGGATGAGT ATAAGAATGA TGTAAAAAAC AGATCTGTTT ATATTAAAGG TTTCCCAACT 
GACGCCACCC TTGATGATAT AAAAGAATGG CTAGACGATA AAGGCCAAAT ACTGAATATT 
CAAATGAGAA GAACATTACA CAAAACATTT AAGGGGTCAA TATTTGCTGT GTTTGATAGT 
ATTCAGTCTG CAAAGAAGTT TGTGGAGATC CCTGGCCAGA AGTACAAAGA CACTAACCTG 
CTAATACTCT TTAAGGAAGA TTACTTTGCA AAAAAAAATG AAGAAAGAAA GCAGAGCAAA 
GTGGAAGCTA AATTAAAAGC TAAACAAGAG CATGAAGGAA GACACAAGCC AGGAAGTACT 
GAAACCAGAG CTCTAGAAGG AAAGATGGGA TGCTTACTGA AGTTTTCAGG TGACTTGGAT 
GACCAGACCT GTAGAGAAGA TTTACACTTC CTTTTCTCAA ATCATGGTGA AATAAAATGG 
GTCGACTTTG CCAGAGGAGC AAAAGAGGGA ATAATTCTCT TCAAAGAAAA GGCTAAGGAA 
GCACTTGAGA AAGCCAGAAA TGCAAATAAT GGTAACCTAC TGTTAAGGAA CAAAAAGGTG 
ACTTGGAAAG TACTAGAAGG ACATGCGGAA AAAGAAGCAT TGAAAAAAAT CACAGATGAT 
CAGCAAGAAT CCCTAAACAA ATGGAAGTCA AAAGGAGGGC ATGGTGGAAG ATTTAAAGGA 
AGCCATGTTT TTACAGCAGC CCGCAGATTT AAAGGAAAAG GGAAGGGTAA TAGGCCTGGT 
TATGCTGGGG CACCCAAAGG AAGAGGACAG TTTCATGGAA GGAGGACAAG ATTTGATGAT 
GATGATCGTC GTCGTGGACC AATGAAAAGA GGAAGAGATG GAAGAGACAG AGAAGAACCC 
GCATCAAAGC ATAAGAAAAG AGAAAATGGT GCTAGAGACA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001342194.1
CDS	178..1422
Translation	MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRRTLHKTFKGSIFAVFDSIQSAKKFVEIPGQKYKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHGEIKWVDFARGAKEGIILFKEKAKEALEKARNANNGNLLLRNKKVTWKVLEGHAEKEALKKITDDQQESLNKWKSKGGHGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRGQFHGRRTRFDDDDRRRGPMKRGRDGRDREEPASKHKKRENGARDK

Target ORF information:

RefSeq Version	NM_001355265.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001355265.1

ORF Insert Sequence:

ATGGCTGAAA ATGGAGATAA TGAAAAAATG ACTGCTTTGG AGGCCAAAAT CTGTCATCAA 
ATTGAGTATT ATTTTGGAGA CTTCAATTTG CCACGAGACA AGTTTTTAAA AGAACAGATC 
AAATTGGATG AAGGCTGGGT ACCTTTGGAA ACAATGATAA AATTCAACAG GCTAAACCGG 
CTGACAACAG ACTTTAATGT AATTGTGCAA GCACTGAGCA AATCTAAGGC AAAACTCATG 
GAAGTCAGTG CAGACAAAAC TAAAATTAGA AGATCACCAA GCAGACCACT CCCTGAAGTG 
ACGGATGAGT ATAAGAATGA TGTAAAAAAC AGATCTGTTT ATATTAAAGG TTTCCCAACT 
GACGCCACCC TTGATGATAT AAAAGAATGG CTAGACGATA AAGGCCAAAT ACTGAATATT 
CAAATGAGAA GAACATTACA CAAAACATTT AAGGGGTCAA TATTTGCTGT GTTTGATAGT 
ATTCAGTCTG CAAAGAAGTT TGTGGAGATC CCTGGCCAGA AGTACAAAGA CACTAACCTG 
CTAATACTCT TTAAGGAAGA TTACTTTGCA AAAAAAAATG AAGAAAGAAA GCAGAGCAAA 
GTGGAAGCTA AATTAAAAGC TAAACAAGAG CATGAAGGAA GACACAAGCC AGGAAGTACT 
GAAACCAGAG CTCTAGAAGG AAAGATGGGA TGCTTACTGA AGTTTTCAGG TGACTTGGAT 
GACCAGACCT GTAGAGAAGA TTTACACTTC CTTTTCTCAA ATCATGGTGA AATAAAATGG 
GTCGACTTTG CCAGAGGAGC AAAAGAGGGA ATAATTCTCT TCAAAGAAAA GGCTAAGGAA 
GCACTTGAGA AAGCCAGAAA TGCAAATAAT GGTAACCTAC TGTTAAGGAA CAAAAAGGTG 
ACTTGGAAAG TACTAGAAGG ACATGCGGAA AAAGAAGCAT TGAAAAAAAT CACAGATGAT 
CAGCAAGAAT CCCTAAACAA ATGGAAGTCA AAAGGAGGGC ATGGTGGAAG ATTTAAAGGA 
AGCCATGTTT TTACAGCAGC CCGCAGATTT AAAGGAAAAG GGAAGGGTAA TAGGCCTGGT 
TATGCTGGGG CACCCAAAGG AAGAGGACAG TTTCATGGAA GGAGGACAAG ATTTGATGAT 
GATGATCGTC GTCGTGGACC AATGAAAAGA GGAAGAGATG GAAGAGACAG AGAAGAACCC 
GCATCAAAGC ATAAGAAAAG AGAAAATGGT GCTAGAGACA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ssb ( XM_006499069.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006499132.1 Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu30203
Clone ID Related Accession (Same CDS sequence)	XM_006499069.2 , NM_001355265.1
Accession Version	XM_006499069.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1245bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	lupus La protein homolog isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006499069.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGAAA ATGGAGATAA TGAAAAAATG ACTGCTTTGG AGGCCAAAAT CTGTCATCAA 
ATTGAGTATT ATTTTGGAGA CTTCAATTTG CCACGAGACA AGTTTTTAAA AGAACAGATC 
AAATTGGATG AAGGCTGGGT ACCTTTGGAA ACAATGATAA AATTCAACAG GCTAAACCGG 
CTGACAACAG ACTTTAATGT AATTGTGCAA GCACTGAGCA AATCTAAGGC AAAACTCATG 
GAAGTCAGTG CAGACAAAAC TAAAATTAGA AGATCACCAA GCAGACCACT CCCTGAAGTG 
ACGGATGAGT ATAAGAATGA TGTAAAAAAC AGATCTGTTT ATATTAAAGG TTTCCCAACT 
GACGCCACCC TTGATGATAT AAAAGAATGG CTAGACGATA AAGGCCAAAT ACTGAATATT 
CAAATGAGAA GAACATTACA CAAAACATTT AAGGGGTCAA TATTTGCTGT GTTTGATAGT 
ATTCAGTCTG CAAAGAAGTT TGTGGAGATC CCTGGCCAGA AGTACAAAGA CACTAACCTG 
CTAATACTCT TTAAGGAAGA TTACTTTGCA AAAAAAAATG AAGAAAGAAA GCAGAGCAAA 
GTGGAAGCTA AATTAAAAGC TAAACAAGAG CATGAAGGAA GACACAAGCC AGGAAGTACT 
GAAACCAGAG CTCTAGAAGG AAAGATGGGA TGCTTACTGA AGTTTTCAGG TGACTTGGAT 
GACCAGACCT GTAGAGAAGA TTTACACTTC CTTTTCTCAA ATCATGGTGA AATAAAATGG 
GTCGACTTTG CCAGAGGAGC AAAAGAGGGA ATAATTCTCT TCAAAGAAAA GGCTAAGGAA 
GCACTTGAGA AAGCCAGAAA TGCAAATAAT GGTAACCTAC TGTTAAGGAA CAAAAAGGTG 
ACTTGGAAAG TACTAGAAGG ACATGCGGAA AAAGAAGCAT TGAAAAAAAT CACAGATGAT 
CAGCAAGAAT CCCTAAACAA ATGGAAGTCA AAAGGAGGGC ATGGTGGAAG ATTTAAAGGA 
AGCCATGTTT TTACAGCAGC CCGCAGATTT AAAGGAAAAG GGAAGGGTAA TAGGCCTGGT 
TATGCTGGGG CACCCAAAGG AAGAGGACAG TTTCATGGAA GGAGGACAAG ATTTGATGAT 
GATGATCGTC GTCGTGGACC AATGAAAAGA GGAAGAGATG GAAGAGACAG AGAAGAACCC 
GCATCAAAGC ATAAGAAAAG AGAAAATGGT GCTAGAGACA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006499132.1
CDS	173..1417
Translation	MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRRTLHKTFKGSIFAVFDSIQSAKKFVEIPGQKYKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHGEIKWVDFARGAKEGIILFKEKAKEALEKARNANNGNLLLRNKKVTWKVLEGHAEKEALKKITDDQQESLNKWKSKGGHGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRGQFHGRRTRFDDDDRRRGPMKRGRDGRDREEPASKHKKRENGARDK

Target ORF information:

RefSeq Version	XM_006499069.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006499069.2

ORF Insert Sequence:

ATGGCTGAAA ATGGAGATAA TGAAAAAATG ACTGCTTTGG AGGCCAAAAT CTGTCATCAA 
ATTGAGTATT ATTTTGGAGA CTTCAATTTG CCACGAGACA AGTTTTTAAA AGAACAGATC 
AAATTGGATG AAGGCTGGGT ACCTTTGGAA ACAATGATAA AATTCAACAG GCTAAACCGG 
CTGACAACAG ACTTTAATGT AATTGTGCAA GCACTGAGCA AATCTAAGGC AAAACTCATG 
GAAGTCAGTG CAGACAAAAC TAAAATTAGA AGATCACCAA GCAGACCACT CCCTGAAGTG 
ACGGATGAGT ATAAGAATGA TGTAAAAAAC AGATCTGTTT ATATTAAAGG TTTCCCAACT 
GACGCCACCC TTGATGATAT AAAAGAATGG CTAGACGATA AAGGCCAAAT ACTGAATATT 
CAAATGAGAA GAACATTACA CAAAACATTT AAGGGGTCAA TATTTGCTGT GTTTGATAGT 
ATTCAGTCTG CAAAGAAGTT TGTGGAGATC CCTGGCCAGA AGTACAAAGA CACTAACCTG 
CTAATACTCT TTAAGGAAGA TTACTTTGCA AAAAAAAATG AAGAAAGAAA GCAGAGCAAA 
GTGGAAGCTA AATTAAAAGC TAAACAAGAG CATGAAGGAA GACACAAGCC AGGAAGTACT 
GAAACCAGAG CTCTAGAAGG AAAGATGGGA TGCTTACTGA AGTTTTCAGG TGACTTGGAT 
GACCAGACCT GTAGAGAAGA TTTACACTTC CTTTTCTCAA ATCATGGTGA AATAAAATGG 
GTCGACTTTG CCAGAGGAGC AAAAGAGGGA ATAATTCTCT TCAAAGAAAA GGCTAAGGAA 
GCACTTGAGA AAGCCAGAAA TGCAAATAAT GGTAACCTAC TGTTAAGGAA CAAAAAGGTG 
ACTTGGAAAG TACTAGAAGG ACATGCGGAA AAAGAAGCAT TGAAAAAAAT CACAGATGAT 
CAGCAAGAAT CCCTAAACAA ATGGAAGTCA AAAGGAGGGC ATGGTGGAAG ATTTAAAGGA 
AGCCATGTTT TTACAGCAGC CCGCAGATTT AAAGGAAAAG GGAAGGGTAA TAGGCCTGGT 
TATGCTGGGG CACCCAAAGG AAGAGGACAG TTTCATGGAA GGAGGACAAG ATTTGATGAT 
GATGATCGTC GTCGTGGACC AATGAAAAGA GGAAGAGATG GAAGAGACAG AGAAGAACCC 
GCATCAAAGC ATAAGAAAAG AGAAAATGGT GCTAGAGACA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ssb ( NM_001110145.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001103615.1 Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu15131
Clone ID Related Accession (Same CDS sequence)	NM_001110145.1 , NM_009278.4
Accession Version	NM_001110145.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1248bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-06
Organism	Mus musculus(house mouse)
Product	lupus La protein homolog isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL845261.17, BX322634.4 and AL929249.15. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.11919.1, SRR1660815.109871.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAA ATGGAGATAA TGAAAAAATG ACTGCTTTGG AGGCCAAAAT CTGTCATCAA 
ATTGAGTATT ATTTTGGAGA CTTCAATTTG CCACGAGACA AGTTTTTAAA AGAACAGATC 
AAATTGGATG AAGGCTGGGT ACCTTTGGAA ACAATGATAA AATTCAACAG GCTAAACCGG 
CTGACAACAG ACTTTAATGT AATTGTGCAA GCACTGAGCA AATCTAAGGC AAAACTCATG 
GAAGTCAGTG CAGACAAAAC TAAAATTAGA AGATCACCAA GCAGACCACT CCCTGAAGTG 
ACGGATGAGT ATAAGAATGA TGTAAAAAAC AGATCTGTTT ATATTAAAGG TTTCCCAACT 
GACGCCACCC TTGATGATAT AAAAGAATGG CTAGACGATA AAGGCCAAAT ACTGAATATT 
CAAATGAGAA GAACATTACA CAAAACATTT AAGGGGTCAA TATTTGCTGT GTTTGATAGT 
ATTCAGTCTG CAAAGAAGTT TGTGGAGATC CCTGGCCAGA AGTACAAAGA CACTAACCTG 
CTAATACTCT TTAAGGAAGA TTACTTTGCA AAAAAAAATG AAGAAAGAAA GCAGAGCAAA 
GTGGAAGCTA AATTAAAAGC TAAACAAGAG CATGAAGGAA GACACAAGCC AGGAAGTACT 
GAAACCAGAG CTCTAGAAGG AAAGATGGGA TGCTTACTGA AGTTTTCAGG TGACTTGGAT 
GACCAGACCT GTAGAGAAGA TTTACACTTC CTTTTCTCAA ATCATGGTGA AATAAAATGG 
GTCGACTTTG CCAGAGGAGC AAAAGAGGGA ATAATTCTCT TCAAAGAAAA GGCTAAGGAA 
GCACTTGAGA AAGCCAGAAA TGCAAATAAT GGTAACCTAC TGTTAAGGAA CAAAAAGGTG 
ACTTGGAAAG TACTAGAAGG ACATGCGGAA AAAGAAGCAT TGAAAAAAAT CACAGATGAT 
CAGCAAGAAT CCCTAAACAA ATGGAAGTCA AAAGGAGGGC ATGCAGGTGG AAGATTTAAA 
GGAAGCCATG TTTTTACAGC AGCCCGCAGA TTTAAAGGAA AAGGGAAGGG TAATAGGCCT 
GGTTATGCTG GGGCACCCAA AGGAAGAGGA CAGTTTCATG GAAGGAGGAC AAGATTTGAT 
GATGATGATC GTCGTCGTGG ACCAATGAAA AGAGGAAGAG ATGGAAGAGA CAGAGAAGAA 
CCCGCATCAA AGCATAAGAA AAGAGAAAAT GGTGCTAGAG ACAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001103615.1
CDS	178..1425
Translation	MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRRTLHKTFKGSIFAVFDSIQSAKKFVEIPGQKYKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHGEIKWVDFARGAKEGIILFKEKAKEALEKARNANNGNLLLRNKKVTWKVLEGHAEKEALKKITDDQQESLNKWKSKGGHAGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRGQFHGRRTRFDDDDRRRGPMKRGRDGRDREEPASKHKKRENGARDK

Target ORF information:

RefSeq Version	NM_001110145.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001110145.1

ORF Insert Sequence:

ATGGCTGAAA ATGGAGATAA TGAAAAAATG ACTGCTTTGG AGGCCAAAAT CTGTCATCAA 
ATTGAGTATT ATTTTGGAGA CTTCAATTTG CCACGAGACA AGTTTTTAAA AGAACAGATC 
AAATTGGATG AAGGCTGGGT ACCTTTGGAA ACAATGATAA AATTCAACAG GCTAAACCGG 
CTGACAACAG ACTTTAATGT AATTGTGCAA GCACTGAGCA AATCTAAGGC AAAACTCATG 
GAAGTCAGTG CAGACAAAAC TAAAATTAGA AGATCACCAA GCAGACCACT CCCTGAAGTG 
ACGGATGAGT ATAAGAATGA TGTAAAAAAC AGATCTGTTT ATATTAAAGG TTTCCCAACT 
GACGCCACCC TTGATGATAT AAAAGAATGG CTAGACGATA AAGGCCAAAT ACTGAATATT 
CAAATGAGAA GAACATTACA CAAAACATTT AAGGGGTCAA TATTTGCTGT GTTTGATAGT 
ATTCAGTCTG CAAAGAAGTT TGTGGAGATC CCTGGCCAGA AGTACAAAGA CACTAACCTG 
CTAATACTCT TTAAGGAAGA TTACTTTGCA AAAAAAAATG AAGAAAGAAA GCAGAGCAAA 
GTGGAAGCTA AATTAAAAGC TAAACAAGAG CATGAAGGAA GACACAAGCC AGGAAGTACT 
GAAACCAGAG CTCTAGAAGG AAAGATGGGA TGCTTACTGA AGTTTTCAGG TGACTTGGAT 
GACCAGACCT GTAGAGAAGA TTTACACTTC CTTTTCTCAA ATCATGGTGA AATAAAATGG 
GTCGACTTTG CCAGAGGAGC AAAAGAGGGA ATAATTCTCT TCAAAGAAAA GGCTAAGGAA 
GCACTTGAGA AAGCCAGAAA TGCAAATAAT GGTAACCTAC TGTTAAGGAA CAAAAAGGTG 
ACTTGGAAAG TACTAGAAGG ACATGCGGAA AAAGAAGCAT TGAAAAAAAT CACAGATGAT 
CAGCAAGAAT CCCTAAACAA ATGGAAGTCA AAAGGAGGGC ATGCAGGTGG AAGATTTAAA 
GGAAGCCATG TTTTTACAGC AGCCCGCAGA TTTAAAGGAA AAGGGAAGGG TAATAGGCCT 
GGTTATGCTG GGGCACCCAA AGGAAGAGGA CAGTTTCATG GAAGGAGGAC AAGATTTGAT 
GATGATGATC GTCGTCGTGG ACCAATGAAA AGAGGAAGAG ATGGAAGAGA CAGAGAAGAA 
CCCGCATCAA AGCATAAGAA AAGAGAAAAT GGTGCTAGAG ACAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ssb ( NM_009278.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033304.1 Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant 1, mRNA.

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CloneID	OMu15131
Clone ID Related Accession (Same CDS sequence)	NM_001110145.1 , NM_009278.4
Accession Version	NM_009278.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1248bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Mus musculus(house mouse)
Product	lupus La protein homolog isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL845261.17, BX322634.4 and AL929249.15. On Oct 25, 2007 this sequence version replaced NM_009278.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L00993.1, SRR1660813.64149.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849385 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAA ATGGAGATAA TGAAAAAATG ACTGCTTTGG AGGCCAAAAT CTGTCATCAA 
ATTGAGTATT ATTTTGGAGA CTTCAATTTG CCACGAGACA AGTTTTTAAA AGAACAGATC 
AAATTGGATG AAGGCTGGGT ACCTTTGGAA ACAATGATAA AATTCAACAG GCTAAACCGG 
CTGACAACAG ACTTTAATGT AATTGTGCAA GCACTGAGCA AATCTAAGGC AAAACTCATG 
GAAGTCAGTG CAGACAAAAC TAAAATTAGA AGATCACCAA GCAGACCACT CCCTGAAGTG 
ACGGATGAGT ATAAGAATGA TGTAAAAAAC AGATCTGTTT ATATTAAAGG TTTCCCAACT 
GACGCCACCC TTGATGATAT AAAAGAATGG CTAGACGATA AAGGCCAAAT ACTGAATATT 
CAAATGAGAA GAACATTACA CAAAACATTT AAGGGGTCAA TATTTGCTGT GTTTGATAGT 
ATTCAGTCTG CAAAGAAGTT TGTGGAGATC CCTGGCCAGA AGTACAAAGA CACTAACCTG 
CTAATACTCT TTAAGGAAGA TTACTTTGCA AAAAAAAATG AAGAAAGAAA GCAGAGCAAA 
GTGGAAGCTA AATTAAAAGC TAAACAAGAG CATGAAGGAA GACACAAGCC AGGAAGTACT 
GAAACCAGAG CTCTAGAAGG AAAGATGGGA TGCTTACTGA AGTTTTCAGG TGACTTGGAT 
GACCAGACCT GTAGAGAAGA TTTACACTTC CTTTTCTCAA ATCATGGTGA AATAAAATGG 
GTCGACTTTG CCAGAGGAGC AAAAGAGGGA ATAATTCTCT TCAAAGAAAA GGCTAAGGAA 
GCACTTGAGA AAGCCAGAAA TGCAAATAAT GGTAACCTAC TGTTAAGGAA CAAAAAGGTG 
ACTTGGAAAG TACTAGAAGG ACATGCGGAA AAAGAAGCAT TGAAAAAAAT CACAGATGAT 
CAGCAAGAAT CCCTAAACAA ATGGAAGTCA AAAGGAGGGC ATGCAGGTGG AAGATTTAAA 
GGAAGCCATG TTTTTACAGC AGCCCGCAGA TTTAAAGGAA AAGGGAAGGG TAATAGGCCT 
GGTTATGCTG GGGCACCCAA AGGAAGAGGA CAGTTTCATG GAAGGAGGAC AAGATTTGAT 
GATGATGATC GTCGTCGTGG ACCAATGAAA AGAGGAAGAG ATGGAAGAGA CAGAGAAGAA 
CCCGCATCAA AGCATAAGAA AAGAGAAAAT GGTGCTAGAG ACAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033304.1
CDS	205..1452
Translation	MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRRTLHKTFKGSIFAVFDSIQSAKKFVEIPGQKYKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHGEIKWVDFARGAKEGIILFKEKAKEALEKARNANNGNLLLRNKKVTWKVLEGHAEKEALKKITDDQQESLNKWKSKGGHAGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRGQFHGRRTRFDDDDRRRGPMKRGRDGRDREEPASKHKKRENGARDK

Target ORF information:

RefSeq Version	NM_009278.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus Sjogren syndrome antigen B (Ssb), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009278.4

ORF Insert Sequence:

ATGGCTGAAA ATGGAGATAA TGAAAAAATG ACTGCTTTGG AGGCCAAAAT CTGTCATCAA 
ATTGAGTATT ATTTTGGAGA CTTCAATTTG CCACGAGACA AGTTTTTAAA AGAACAGATC 
AAATTGGATG AAGGCTGGGT ACCTTTGGAA ACAATGATAA AATTCAACAG GCTAAACCGG 
CTGACAACAG ACTTTAATGT AATTGTGCAA GCACTGAGCA AATCTAAGGC AAAACTCATG 
GAAGTCAGTG CAGACAAAAC TAAAATTAGA AGATCACCAA GCAGACCACT CCCTGAAGTG 
ACGGATGAGT ATAAGAATGA TGTAAAAAAC AGATCTGTTT ATATTAAAGG TTTCCCAACT 
GACGCCACCC TTGATGATAT AAAAGAATGG CTAGACGATA AAGGCCAAAT ACTGAATATT 
CAAATGAGAA GAACATTACA CAAAACATTT AAGGGGTCAA TATTTGCTGT GTTTGATAGT 
ATTCAGTCTG CAAAGAAGTT TGTGGAGATC CCTGGCCAGA AGTACAAAGA CACTAACCTG 
CTAATACTCT TTAAGGAAGA TTACTTTGCA AAAAAAAATG AAGAAAGAAA GCAGAGCAAA 
GTGGAAGCTA AATTAAAAGC TAAACAAGAG CATGAAGGAA GACACAAGCC AGGAAGTACT 
GAAACCAGAG CTCTAGAAGG AAAGATGGGA TGCTTACTGA AGTTTTCAGG TGACTTGGAT 
GACCAGACCT GTAGAGAAGA TTTACACTTC CTTTTCTCAA ATCATGGTGA AATAAAATGG 
GTCGACTTTG CCAGAGGAGC AAAAGAGGGA ATAATTCTCT TCAAAGAAAA GGCTAAGGAA 
GCACTTGAGA AAGCCAGAAA TGCAAATAAT GGTAACCTAC TGTTAAGGAA CAAAAAGGTG 
ACTTGGAAAG TACTAGAAGG ACATGCGGAA AAAGAAGCAT TGAAAAAAAT CACAGATGAT 
CAGCAAGAAT CCCTAAACAA ATGGAAGTCA AAAGGAGGGC ATGCAGGTGG AAGATTTAAA 
GGAAGCCATG TTTTTACAGC AGCCCGCAGA TTTAAAGGAA AAGGGAAGGG TAATAGGCCT 
GGTTATGCTG GGGCACCCAA AGGAAGAGGA CAGTTTCATG GAAGGAGGAC AAGATTTGAT 
GATGATGATC GTCGTCGTGG ACCAATGAAA AGAGGAAGAG ATGGAAGAGA CAGAGAAGAA 
CCCGCATCAA AGCATAAGAA AAGAGAAAAT GGTGCTAGAG ACAAGTAG