Fgl2 cDNA ORF clone, Mus musculus(house mouse)

Inhibition of the FGL2:Fc?RIIB/RIII Immunosuppressive Pathway Enhances Antiviral T cell and B Cell Responses Leading to Clearance of LCMV cl-13.
Klingberg O, Khattar R, Farrokhi K, Ferri D, Yavorska N, Zhang J, Sadozai H, Adeyi O, Chruscinski A, Levy GA, Selzner N
Immunology(2018 Jan)

In vitro IL-33 treatment abrogated MHV-3 and IFN-gamma induced FGL2 expression in RAW264.7 and THP-1 cells.
Title: IL-33 protects murine viral fulminant hepatitis by targeting coagulation hallmark protein FGL2/fibroleukin expression.

PD-1 plays a vital role in brain inflammation via regulation of Fgl-2 after ICH, and that manipulation of PD-1 might be a promising therapeutical target in ICH.
Title: Programmed death (PD)-1 attenuates macrophage activation and brain inflammation via regulation of fibrinogen-like protein 2 (Fgl-2) after intracerebral hemorrhage in mice.

FGL2 appears as one of the key players in immune regulatory processes favoring metacestode survival by promoting Regulatory T-cell activity and IL-17A production that contributes to FGL2-regulation.
Title: Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4+ CD25+ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice.

TNF-alpha, and FGL2 form an integral network that contributes to coagulation and complement activation, and suggest that those are potential therapeutic targets in viral FH intervention.
Title: C5aR, TNF-?, and FGL2 contribute to coagulation and complement activation in virus-induced fulminant hepatitis.

these data strongly suggest that Treg cells expressing FGL2 mediate rapamycin-induced tolerance. Furthermore, a gene biomarker panel that includes fgl2 can distinguish between rejecting and tolerant grafts.
Title: The regulatory T cell effector molecule fibrinogen-like protein 2 is necessary for the development of rapamycin-induced tolerance to fully MHC-mismatched murine cardiac allografts.