Ctrl cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ctrl
Entrez Gene ID	109660
Full Name	chymotrypsin-like
Synonyms	0910001G08Rik,1810004D15Rik,AV005227,Ctra-1,Ctra1,chymopasin,mFLJ00366
General protein information	Preferred Names chymotrypsin-like Names chymotrypsin-like protease CTRL-1 chymotrypsin A CTRA-1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8 D3\|8 53.06 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_023182.2	NP_075671.1	chymotrypsin-like protease CTRL-1 precursor

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	CTRL	NP_001264554.1
Danio rerio (zebrafish)	ctrl	NP_001004582.1
	CTRL	XP_001089922.2
Mus musculus (house mouse)	Ctrl	NP_075671.1
Pan troglodytes (chimpanzee)	CTRL	XP_511044.3
Canis lupus familiaris (dog)	CTRL	XP_853830.2
Rattus norvegicus (Norway rat)	Ctrl	NP_446461.1
Danio rerio (zebrafish)	zgc:171592	XP_005157839.1
Homo sapiens (human)	CTRL	NP_001898.1

Gene Ontology
Bibliography

Related articles in PubMed

The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.
Hale MA, Swift GH, Hoang CQ, Deering TG, Masui T, Lee YK, Xue J, MacDonald RJ
Development (Cambridge, England)141(16)3123-33(2014 Aug)

Transforming growth factor Beta2 is required for valve remodeling during heart development.
Azhar M, Brown K, Gard C, Chen H, Rajan S, Elliott DA, Stevens MV, Camenisch TD, Conway SJ, Doetschman T
Developmental dynamics : an official publication of the American Association of Anatomists240(9)2127-41(2011 Sep)

Local protease signaling contributes to neural tube closure in the mouse embryo.
Camerer E, Barker A, Duong DN, Ganesan R, Kataoka H, Cornelissen I, Darragh MR, Hussain A, Zheng YW, Srinivasan Y, Brown C, Xu SM, Regard JB, Lin CY, Craik CS, Kirchhofer D, Coughlin SR
Developmental cell18(1)25-38(2010 Jan)

Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.
Szabo R, Hobson JP, Christoph K, Kosa P, List K, Bugge TH
Development (Cambridge, England)136(15)2653-63(2009 Aug)

Identification of transcripts with enriched expression in the developing and adult pancreas.
Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD
Genome biology9(6)R99(2008)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ctrl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ctrl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00499	NM_023182.2 Latest version!	Mus musculus chymotrypsin-like (Ctrl), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ctrl ( NM_023182.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_075671.1 Mus musculus chymotrypsin-like (Ctrl), mRNA.

Price & Availability↑

CloneID	OMu00499
Clone ID Related Accession (Same CDS sequence)	NM_023182.2
Accession Version	NM_023182.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-25
Organism	Mus musculus(house mouse)
Product	chymotrypsin-like protease CTRL-1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB016228.1 and CF582693.1. On Apr 8, 2006 this sequence version replaced NM_023182.1. ##Evidence-Data-START## Transcript exon combination :: AB016228.1, BC087918.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTACTGC TCAGCCTAAC CCTTAGCCTG GTCCTCCTTG GCTCCTCCTG GGGCTGTGGT 
GTTCCTGCCA TCACGCCTGC ACTGAGCTAC AATCAGAGAA TTGTCAACGG GGAGAATGCA 
GTGCCAGGCT CCTGGCCCTG GCAGGTGTCT CTCCAGGATA ACACCGGCTT CCACTTCTGC 
GGTGGTTCTC TCATCAGTCC GAACTGGGTG GTCACGGCTG CCCACTGCCA AGTCACGCCT 
GGACGCCACT TTGTCGTTTT GGGAGAATAT GACCGATCTT CCAATGCTGA ACCTGTGCAG 
GTCCTCTCGA TCGCAAGGGC CATCACACAC CCTAACTGGA ACGCCAACAC CATGAACAAT 
GACCTGACTC TCCTGAAGCT TGCCTCGCCA GCCCGGTACA CAGCACAAGT CTCACCAGTC 
TGCCTGGCTT CCACAAACGA GGCACTGCCT TCGGGGCTCA CCTGTGTCAC CACTGGCTGG 
GGCCGAATCA GTGGTGTGGG CAATGTGACA CCAGCTCGCC TGCAGCAAGT TGTTCTACCC 
CTGGTCACTG TGAATCAGTG TCGGCAGTAC TGGGGTGCAC GCATTACCGA TGCCATGATA 
TGTGCAGGTG GCTCAGGCGC CTCCTCATGT CAGGGTGACT CAGGAGGCCC TCTTGTCTGC 
CAGAAGGGAA ACACCTGGGT GCTTATTGGG ATTGTCTCCT GGGGCACTAA GAACTGCAAC 
ATACAAGCAC CGGCCATGTA CACTCGGGTC AGCAAGTTCA GTACCTGGAT CAACCAAGTC 
ATGGCCTACA ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_075671.1
CDS	33..827
Translation	MLLLSLTLSLVLLGSSWGCGVPAITPALSYNQRIVNGENAVPGSWPWQVSLQDNTGFHFCGGSLISPNWVVTAAHCQVTPGRHFVVLGEYDRSSNAEPVQVLSIARAITHPNWNANTMNNDLTLLKLASPARYTAQVSPVCLASTNEALPSGLTCVTTGWGRISGVGNVTPARLQQVVLPLVTVNQCRQYWGARITDAMICAGGSGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNIQAPAMYTRVSKFSTWINQVMAYN

Target ORF information:

RefSeq Version	NM_023182.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus chymotrypsin-like (Ctrl), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023182.2

ORF Insert Sequence:

ATGCTACTGC TCAGCCTAAC CCTTAGCCTG GTCCTCCTTG GCTCCTCCTG GGGCTGTGGT 
GTTCCTGCCA TCACGCCTGC ACTGAGCTAC AATCAGAGAA TTGTCAACGG GGAGAATGCA 
GTGCCAGGCT CCTGGCCCTG GCAGGTGTCT CTCCAGGATA ACACCGGCTT CCACTTCTGC 
GGTGGTTCTC TCATCAGTCC GAACTGGGTG GTCACGGCTG CCCACTGCCA AGTCACGCCT 
GGACGCCACT TTGTCGTTTT GGGAGAATAT GACCGATCTT CCAATGCTGA ACCTGTGCAG 
GTCCTCTCGA TCGCAAGGGC CATCACACAC CCTAACTGGA ACGCCAACAC CATGAACAAT 
GACCTGACTC TCCTGAAGCT TGCCTCGCCA GCCCGGTACA CAGCACAAGT CTCACCAGTC 
TGCCTGGCTT CCACAAACGA GGCACTGCCT TCGGGGCTCA CCTGTGTCAC CACTGGCTGG 
GGCCGAATCA GTGGTGTGGG CAATGTGACA CCAGCTCGCC TGCAGCAAGT TGTTCTACCC 
CTGGTCACTG TGAATCAGTG TCGGCAGTAC TGGGGTGCAC GCATTACCGA TGCCATGATA 
TGTGCAGGTG GCTCAGGCGC CTCCTCATGT CAGGGTGACT CAGGAGGCCC TCTTGTCTGC 
CAGAAGGGAA ACACCTGGGT GCTTATTGGG ATTGTCTCCT GGGGCACTAA GAACTGCAAC 
ATACAAGCAC CGGCCATGTA CACTCGGGTC AGCAAGTTCA GTACCTGGAT CAACCAAGTC 
ATGGCCTACA ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.
Development (Cambridge, England)141(16)3123-33(2014 Aug)
Hale MA,Swift GH,Hoang CQ,Deering TG,Masui T,Lee YK,Xue J,MacDonald RJ

Transforming growth factor Beta2 is required for valve remodeling during heart development.
Developmental dynamics : an official publication of the American Association of Anatomists240(9)2127-41(2011 Sep)
Azhar M,Brown K,Gard C,Chen H,Rajan S,Elliott DA,Stevens MV,Camenisch TD,Conway SJ,Doetschman T

Local protease signaling contributes to neural tube closure in the mouse embryo.
Developmental cell18(1)25-38(2010 Jan)
Camerer E,Barker A,Duong DN,Ganesan R,Kataoka H,Cornelissen I,Darragh MR,Hussain A,Zheng YW,Srinivasan Y,Brown C,Xu SM,Regard JB,Lin CY,Craik CS,Kirchhofer D,Coughlin SR

Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.
Development (Cambridge, England)136(15)2653-63(2009 Aug)
Szabo R,Hobson JP,Christoph K,Kosa P,List K,Bugge TH

Identification of transcripts with enriched expression in the developing and adult pancreas.
Genome biology9(6)R99(2008)
Hoffman BG,Zavaglia B,Witzsche J,Ruiz de Algara T,Beach M,Hoodless PA,Jones SJ,Marra MA,Helgason CD