Imp3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Imp3
Entrez Gene ID	102462
Full Name	IMP3, U3 small nucleolar ribonucleoprotein
Synonyms	1190002L16Rik,AI256594
General protein information	Preferred Names IMP3, U3 small nucleolar ribonucleoprotein Names U3 small nucleolar ribonucleoprotein protein IMP3 IMP3, U3 small nucleolar ribonucleoprotein, homolog U3 snoRNP protein 3 homolog U3 snoRNP protein IMP3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 B

mRNA and Protein(s)

mRNA	Protein	Name
NM_133976.2	NP_598737.1	U3 small nucleolar ribonucleoprotein protein IMP3

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Imp3	NP_001101622.1
Saccharomyces cerevisiae (baker's yeast)	IMP3	NP_012018.1
Schizosaccharomyces pombe (fission yeast)	imp3	NP_594903.1
Oryza sativa (rice)	Os04g0662100	NP_001054154.1
Xenopus tropicalis (tropical clawed frog)	imp3	NP_001004848.1
	IMP3	XP_001103881.1
Mus musculus (house mouse)	Imp3	NP_598737.1
Danio rerio (zebrafish)	imp3	NP_956561.1
Drosophila melanogaster (fruit fly)	CG4866	NP_611224.1
Caenorhabditis elegans (roundworm)	C48B6.2	NP_491972.1
Magnaporthe oryzae (rice blast fungus)	MGG_04201	XP_003719621.1
Arabidopsis thaliana (thale cress)	AT5G15750	NP_568321.1
Bos taurus (cattle)	IMP3	NP_001073056.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006372	XP_316402.2
Kluyveromyces lactis	KLLA0E15995g	XP_454669.1
Eremothecium gossypii	AGOS_ADL131C	NP_983965.1
Neurospora crassa	NCU01008	XP_961620.1
Homo sapiens (human)	IMP3	NP_060755.1
Pan troglodytes (chimpanzee)	IMP3	XP_510683.2
Canis lupus familiaris (dog)	IMP3	XP_544781.3

Gene Ontology
Bibliography

Related articles in PubMed

Up-regulation of Imp3 confers in vivo tumorigenicity on murine osteosarcoma cells.
Ueki A, Shimizu T, Masuda K, Yamaguchi SI, Ishikawa T, Sugihara E, Onishi N, Kuninaka S, Miyoshi K, Muto A, Toyama Y, Banno K, Aoki D, Saya H
PloS one7(11)e50621(2012)

The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes.
Granneman S, Gallagher JE, Vogelzangs J, Horstman W, van Venrooij WJ, Baserga SJ, Pruijn GJ
Nucleic acids research31(7)1877-87(2003 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Imp3 as a key regulator of stem-like tumorigenic characteristics in osteosarcoma cells
Title: Up-regulation of Imp3 confers in vivo tumorigenicity on murine osteosarcoma cells.

The following Imp3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Imp3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58410	NM_133976.2 Latest version!	Mus musculus IMP3, U3 small nucleolar ribonucleoprotein (Imp3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Imp3 ( NM_133976.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598737.1 Mus musculus IMP3, U3 small nucleolar ribonucleoprotein (Imp3), mRNA.

Price & Availability↑

CloneID	OMu58410
Clone ID Related Accession (Same CDS sequence)	NM_133976.2
Accession Version	NM_133976.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	U3 small nucleolar ribonucleoprotein protein IMP3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC009145.1. On Apr 6, 2007 this sequence version replaced NM_133976.1. ##Evidence-Data-START## Transcript is intronless :: BC009145.1, BG870042.1 [ECO:0000345] ##Evidence-Data-END##

ATGGTGCGGA AGCTTAAGTT CCACGAGCAG AAGCTGCTGA AACAGGTGGA CTTCCTAAAC 
TGGGAAGTCA CCGACCACAA CCTCCACGAA CTGCGTGTGC TGCGGCGGTA CCGGCTGCAG 
CGGCGCGAGG AGTACACGCG CTACAACCAG CTGAGCCGAG CGGTGCGCGA GCTGGCGCGG 
CGCCTGCGCG ACCTGCCGGA ACGCGACCCA TTCCGCGTGC GCGCCTCGGC GGCGCTGTTG 
GACAAGCTGT ACGCTATGGG CCTGGTGCCC ACGCGCGGCT CACTGGAACT CTGCGACTCC 
GTCTCGGCCT CGTCCTTCTG CCGCCGCCGC TTGCCTACTT TGCTCCTCAA GCTACGCATG 
GCGCAGCATC TCCAAGCTGC TGTGGCTTTT GTGGAGCAGG GTCATGTCCG CGTGGGCCCA 
GACGTGGTCA CTGATCCCGC CTTTCTCGTC ACTCGCAGCA TGGAGGACTT TGTCACCTGG 
GTGGACTCAT CCAAGATCAA GCGGCACGTG TTGGAGTACA ATGAGGAGCG CGATGACTTT 
GATCTAGATG CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598737.1
CDS	8..562
Translation	MVRKLKFHEQKLLKQVDFLNWEVTDHNLHELRVLRRYRLQRREEYTRYNQLSRAVRELARRLRDLPERDPFRVRASAALLDKLYAMGLVPTRGSLELCDSVSASSFCRRRLPTLLLKLRMAQHLQAAVAFVEQGHVRVGPDVVTDPAFLVTRSMEDFVTWVDSSKIKRHVLEYNEERDDFDLDA

Target ORF information:

RefSeq Version	NM_133976.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus IMP3, U3 small nucleolar ribonucleoprotein (Imp3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133976.2

ORF Insert Sequence:

ATGGTGCGGA AGCTTAAGTT CCACGAGCAG AAGCTGCTGA AACAGGTGGA CTTCCTAAAC 
TGGGAAGTCA CCGACCACAA CCTCCACGAA CTGCGTGTGC TGCGGCGGTA CCGGCTGCAG 
CGGCGCGAGG AGTACACGCG CTACAACCAG CTGAGCCGAG CGGTGCGCGA GCTGGCGCGG 
CGCCTGCGCG ACCTGCCGGA ACGCGACCCA TTCCGCGTGC GCGCCTCGGC GGCGCTGTTG 
GACAAGCTGT ACGCTATGGG CCTGGTGCCC ACGCGCGGCT CACTGGAACT CTGCGACTCC 
GTCTCGGCCT CGTCCTTCTG CCGCCGCCGC TTGCCTACTT TGCTCCTCAA GCTACGCATG 
GCGCAGCATC TCCAAGCTGC TGTGGCTTTT GTGGAGCAGG GTCATGTCCG CGTGGGCCCA 
GACGTGGTCA CTGATCCCGC CTTTCTCGTC ACTCGCAGCA TGGAGGACTT TGTCACCTGG 
GTGGACTCAT CCAAGATCAA GCGGCACGTG TTGGAGTACA ATGAGGAGCG CGATGACTTT 
GATCTAGATG CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Up-regulation of Imp3 confers in vivo tumorigenicity on murine osteosarcoma cells.
PloS one7(11)e50621(2012)
Ueki A,Shimizu T,Masuda K,Yamaguchi SI,Ishikawa T,Sugihara E,Onishi N,Kuninaka S,Miyoshi K,Muto A,Toyama Y,Banno K,Aoki D,Saya H

The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes.
Nucleic acids research31(7)1877-87(2003 Apr)
Granneman S,Gallagher JE,Vogelzangs J,Horstman W,van Venrooij WJ,Baserga SJ,Pruijn GJ