Yy2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Yy2
Entrez Gene ID	100073351
Full Name	Yy2 transcription factor
General protein information	Preferred Names Yy2 transcription factor Names transcription factor YY2 YY-2 yin and yang 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X F4\|X

mRNA and Protein(s)

mRNA	Protein	Name
NM_001098723.1	NP_001092193.1	transcription factor YY2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	YY2	XP_529235.2
Canis lupus familiaris (dog)	LOC102152457	XP_005641250.1
Homo sapiens (human)	YY2	NP_996806.2
Mus musculus (house mouse)	Yy2	NP_001092193.1
	LOC696656	XP_001087143.1

Gene Ontology
Bibliography

Related articles in PubMed

Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2.
Tahmasebi S, Jafarnejad SM, Tam IS, Gonatopoulos-Pournatzis T, Matta-Camacho E, Tsukumo Y, Yanagiya A, Li W, Atlasi Y, Caron M, Braunschweig U, Pearl D, Khoutorsky A, Gkogkas CG, Nadon R, Bourque G, Yang XJ, Tian B, Stunnenberg HG, Yamanaka Y, Blencowe BJ, Gigu?re V, Sonenberg N
Proceedings of the National Academy of Sciences of the United States of America113(44)12360-12367(2016 Nov)

Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2.
Kakizaki F, Sonoshita M, Miyoshi H, Itatani Y, Ito S, Kawada K, Sakai Y, Taketo MM
Cancer science107(11)1622-1631(2016 Nov)

Transcription factor Yin-Yang 2 alters neuronal outgrowth in vitro.
Klar M, Fenske P, Vega FR, Dame C, Br?uer AU
Cell and tissue research362(2)453-60(2015 Nov)

Association of Rex-1 to target genes supports its interaction with Polycomb function.
Garcia-Tu?on I, Guallar D, Alonso-Martin S, Benito AA, Ben?tez-L?zaro A, P?rez-Palacios R, Muniesa P, Climent M, S?nchez M, Vidal M, Schoorlemmer J
Stem cell research7(1)1-16(2011 Jul)

Developmental expression profile of the YY2 gene in mice.
Drews D, Klar M, Dame C, Br?uer AU
BMC developmental biology945(2009 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

in a transplantation mouse model of liver metastases, expression of Yy2 (and therefore of Aes) is downregulated
Title: Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2.

both the up- and down-regulation of yy2 significantly impairs the outgrowth of the major neurite of primary hippocampal neurons and the numbers of neuronal processes in proximate extensions
Title: Transcription factor Yin-Yang 2 alters neuronal outgrowth in vitro.

Yy2 expression in the heart and lung is constitutively expressed during embryogenesis and in adult mice. Developmental changes of yy2 transcription became obvious in various areas of the brain.
Title: Developmental expression profile of the YY2 gene in mice.

the novel factor YY2 antagonizes the negative actions exerted by YY1
Title: Enhanceosome formation over the beta interferon promoter underlies a remote-control mechanism mediated by YY1 and YY2.

The following Yy2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Yy2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58176	NM_001098723.1 Latest version!	Mus musculus Yy2 transcription factor (Yy2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Yy2 ( NM_001098723.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001092193.1 Mus musculus Yy2 transcription factor (Yy2), mRNA.

Price & Availability↑

CloneID	OMu58176
Clone ID Related Accession (Same CDS sequence)	NM_001098723.1
Accession Version	NM_001098723.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-20
Organism	Mus musculus(house mouse)
Product	transcription factor YY2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK161451.1. ##Evidence-Data-START## Transcript is intronless :: AK161451.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCTG AGACAGAGAA ACTTCTGTGT CTTAACACAG AAAGCGCAGA GATTCCTGCT 
GATTTTGTGG AGCTGCTGCC ACCGGATAAT ATCGGTGATA TCGAGGCGGT TTCTCTGGAA 
ACCAGCGTAG GCCAAACCAT CGAAGTATAT GGAGATGTAG GTGTCGATTG GGCGCATGGT 
AGCCAATACC ACTCTCCTGT TATTGCTCTG CAGCCGCTTG TGGGCAGCAG CCTGAGTAGT 
AGAGATCATG ATAAGGAAAT GTTTGTCGTT CAGACACGAG AGGAGGAGGT GGTGGGCTAC 
CAAGACTCAG ACAACCTACT ATTCAGTCCT GAATTTGGAA GCCAGATGGT TTTGCCAGTT 
AATGAAGACG ACTATCTCCA GCCGACCACT GCCTCTTTTA CGGGCTTTCT GGCGGCAGAG 
AATGGTCAAG GTGAGCTCAG CCCCTATGAA GGGAATCTCT GTGGTTTGAC GACCTTTATA 
GAGGCCGGTG CAGAAGAAAG CGTGAACGCT GACCTGGGTG ACAAACAGTG GGAGCAGAAG 
CAGATCGATG GTCTTGATGG CGAATTTCCC TTCACCATGT GGGACGATGT TAATGAAAAA 
GAAGATCCCA TAGCTGAAGA ACAGGCTGGT GAGTCACCCC CCGATTATTC TGAGTATATG 
ACAGGAAAGA AATTTCCTCC TGAAGGAATA CCTGGCATTG ATCTTTCTGA TCCCAAACAA 
CTGGCAGAAT TTACTAGCAT GAGACCCAAA AAGCCAAAAG GAGACTTTCC AAGACCTATA 
GCATGCTCTC ATAAAGGCTG CGAGAAGATG TTCAAAGATA ATTCTGCTAT GAGAAAGCAC 
TTGCACATCC ATGGGCCGAG AGTGCATGTC TGTGCAGAAT GTGGCAAAGC TTTTGTTGAG 
AGTTCCAAGC TGAAACGTCA TCAGCTTGTT CACACTGGAG AGAAACCCTA CCAGTGTACC 
TTTGAAGGCT GTGGGAGACG CTTTTCCCTG GATTTCAATT TGCGCACACA TGTGCGAATC 
CATACTGGAG ACAAACCTTT CGTGTGTCCA TTTGATGCCT GCAACAAGAA GTTTGCACAG 
TCAACAAACC TGAAATCGCA TATCTTAACC CATGTTAAGA ACAAGAATGA CCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001092193.1
CDS	218..1354
Translation	MASETEKLLCLNTESAEIPADFVELLPPDNIGDIEAVSLETSVGQTIEVYGDVGVDWAHGSQYHSPVIALQPLVGSSLSSRDHDKEMFVVQTREEEVVGYQDSDNLLFSPEFGSQMVLPVNEDDYLQPTTASFTGFLAAENGQGELSPYEGNLCGLTTFIEAGAEESVNADLGDKQWEQKQIDGLDGEFPFTMWDDVNEKEDPIAEEQAGESPPDYSEYMTGKKFPPEGIPGIDLSDPKQLAEFTSMRPKKPKGDFPRPIACSHKGCEKMFKDNSAMRKHLHIHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPYQCTFEGCGRRFSLDFNLRTHVRIHTGDKPFVCPFDACNKKFAQSTNLKSHILTHVKNKNDQ

Target ORF information:

RefSeq Version	NM_001098723.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus Yy2 transcription factor (Yy2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098723.1

ORF Insert Sequence:

ATGGCCTCTG AGACAGAGAA ACTTCTGTGT CTTAACACAG AAAGCGCAGA GATTCCTGCT 
GATTTTGTGG AGCTGCTGCC ACCGGATAAT ATCGGTGATA TCGAGGCGGT TTCTCTGGAA 
ACCAGCGTAG GCCAAACCAT CGAAGTATAT GGAGATGTAG GTGTCGATTG GGCGCATGGT 
AGCCAATACC ACTCTCCTGT TATTGCTCTG CAGCCGCTTG TGGGCAGCAG CCTGAGTAGT 
AGAGATCATG ATAAGGAAAT GTTTGTCGTT CAGACACGAG AGGAGGAGGT GGTGGGCTAC 
CAAGACTCAG ACAACCTACT ATTCAGTCCT GAATTTGGAA GCCAGATGGT TTTGCCAGTT 
AATGAAGACG ACTATCTCCA GCCGACCACT GCCTCTTTTA CGGGCTTTCT GGCGGCAGAG 
AATGGTCAAG GTGAGCTCAG CCCCTATGAA GGGAATCTCT GTGGTTTGAC GACCTTTATA 
GAGGCCGGTG CAGAAGAAAG CGTGAACGCT GACCTGGGTG ACAAACAGTG GGAGCAGAAG 
CAGATCGATG GTCTTGATGG CGAATTTCCC TTCACCATGT GGGACGATGT TAATGAAAAA 
GAAGATCCCA TAGCTGAAGA ACAGGCTGGT GAGTCACCCC CCGATTATTC TGAGTATATG 
ACAGGAAAGA AATTTCCTCC TGAAGGAATA CCTGGCATTG ATCTTTCTGA TCCCAAACAA 
CTGGCAGAAT TTACTAGCAT GAGACCCAAA AAGCCAAAAG GAGACTTTCC AAGACCTATA 
GCATGCTCTC ATAAAGGCTG CGAGAAGATG TTCAAAGATA ATTCTGCTAT GAGAAAGCAC 
TTGCACATCC ATGGGCCGAG AGTGCATGTC TGTGCAGAAT GTGGCAAAGC TTTTGTTGAG 
AGTTCCAAGC TGAAACGTCA TCAGCTTGTT CACACTGGAG AGAAACCCTA CCAGTGTACC 
TTTGAAGGCT GTGGGAGACG CTTTTCCCTG GATTTCAATT TGCGCACACA TGTGCGAATC 
CATACTGGAG ACAAACCTTT CGTGTGTCCA TTTGATGCCT GCAACAAGAA GTTTGCACAG 
TCAACAAACC TGAAATCGCA TATCTTAACC CATGTTAAGA ACAAGAATGA CCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2.
Proceedings of the National Academy of Sciences of the United States of America113(44)12360-12367(2016 Nov)
Tahmasebi S,Jafarnejad SM,Tam IS,Gonatopoulos-Pournatzis T,Matta-Camacho E,Tsukumo Y,Yanagiya A,Li W,Atlasi Y,Caron M,Braunschweig U,Pearl D,Khoutorsky A,Gkogkas CG,Nadon R,Bourque G,Yang XJ,Tian B,Stunnenberg HG,Yamanaka Y,Blencowe BJ,Gigu?re V,Sonenberg N

Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2.
Cancer science107(11)1622-1631(2016 Nov)
Kakizaki F,Sonoshita M,Miyoshi H,Itatani Y,Ito S,Kawada K,Sakai Y,Taketo MM

Transcription factor Yin-Yang 2 alters neuronal outgrowth in vitro.
Cell and tissue research362(2)453-60(2015 Nov)
Klar M,Fenske P,Vega FR,Dame C,Br?uer AU

Association of Rex-1 to target genes supports its interaction with Polycomb function.
Stem cell research7(1)1-16(2011 Jul)
Garcia-Tu?on I,Guallar D,Alonso-Martin S,Benito AA,Ben?tez-L?zaro A,P?rez-Palacios R,Muniesa P,Climent M,S?nchez M,Vidal M,Schoorlemmer J

Developmental expression profile of the YY2 gene in mice.
BMC developmental biology945(2009 Jul)
Drews D,Klar M,Dame C,Br?uer AU

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Yy2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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