| Gene Symbol | TRIP12 |
| Entrez Gene ID | 9320 |
| Full Name | thyroid hormone receptor interactor 12 |
| Synonyms | MRD49,TRIP-12,ULF |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53. [provided by RefSeq, Jan 2017]. |
| Disorder MIM: | |
| Disorder Html: | Mental retardation, autosomal dominant 49, 617752 (3) |








































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