PRAC1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PRAC1
Entrez Gene ID	84366
Full Name	PRAC1 small nuclear protein
Synonyms	C17orf92,PRAC
General protein information	Preferred Names PRAC1 small nuclear protein Names small nuclear protein PRAC1 prostate cancer susceptibility candidate 1 prostate cancer susceptibility candidate protein 1 prostate, rectum and colon expressed gene protein small nuclear protein PRAC
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.32
Summary	This gene is reported to be specifically expressed in prostate, rectum and distal colon. Sequence analysis suggests that it may play a regulatory role in the nucleus. [provided by RefSeq, Jul 2008].
Disorder MIM:	609819

mRNA and Protein(s)

mRNA	Protein	Name
NM_032391.2	NP_115767.1	small nuclear protein PRAC1
NM_032391.3	NP_115767.1	small nuclear protein PRAC1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PRAC	XP_003315422.1
Homo sapiens (human)	PRAC1	NP_115767.1

Gene Ontology
Bibliography

Related articles in PubMed

Clinical Implications and Prognostic Values of Prostate Cancer Susceptibility Candidate Methylation in Primary Nonmuscle Invasive Bladder Cancer.
Kim YW, Yoon HY, Seo SP, Lee SK, Kang HW, Kim WT, Bang HJ, Ryu DH, Yun SJ, Lee SC, Kim WJ, Kim YJ
Disease markers2015402963(2015)

Aberrant expression of the PRAC gene in prostate cancer.
Lenka G, Weng WH, Chuang CK, Ng KF, Pang ST
International journal of oncology43(6)1960-6(2013 Dec)

PRAC: A novel small nuclear protein that is specifically expressed in human prostate and colon.
Liu XF, Olsson P, Wolfgang CD, Bera TK, Duray P, Lee B, Pastan I
The Prostate47(2)125-31(2001 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Enhanced methylation of PRAC was positively associated with a high rate of recurrence and progression in nonmuscle invasive bladder cancer patients.
Title: Clinical Implications and Prognostic Values of Prostate Cancer Susceptibility Candidate Methylation in Primary Nonmuscle Invasive Bladder Cancer.

the pathogenesis of prostate cancer may be due to the expression levels of PRAC protein, and this protein can serve as a potential biomarker for the management of prostate cancer.
Title: Aberrant expression of the PRAC gene in prostate cancer.

The following PRAC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRAC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25952	NM_032391.3 Latest version!	Homo sapiens PRAC1 small nuclear protein (PRAC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu25952	NM_032391.2	Homo sapiens PRAC1 small nuclear protein (PRAC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PRAC1 ( NM_032391.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_115767.1 Homo sapiens PRAC1 small nuclear protein (PRAC1), mRNA.

Price & Availability↑

CloneID	OHu25952
Clone ID Related Accession (Same CDS sequence)	NM_032391.2 , NM_032391.3
Accession Version	NM_032391.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 174bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	small nuclear protein PRAC1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF331165.1, BC030950.1 and BU535394.1. On Jan 13, 2004 this sequence version replaced NM_032391.1. ##Evidence-Data-START## Transcript exon combination :: CF124750.1, BU535394.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGTTGTGCG CCCATTTCTC AGATCAAGGA CCGGCCCATC TTACTACCTC CAAGAGTGCT 
TTTCTCTCTA ATAAGAAAAC ATCTACTTTG AAACATCTAC TGGGCGAGAC CAGGAGTGAT 
GGCTCAGCCT GTAATTCTGG AATTTCGGGA GGCCGAGGCA GGAAGATTCC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115767.1
CDS	129..302
Translation	MLCAHFSDQGPAHLTTSKSAFLSNKKTSTLKHLLGETRSDGSACNSGISGGRGRKIP

Target ORF information:

RefSeq Version	NM_032391.2
Organism	Homo sapiens(human)
Definition	Homo sapiens PRAC1 small nuclear protein (PRAC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032391.2

ORF Insert Sequence:

1
61
121

ATGTTGTGCG CCCATTTCTC AGATCAAGGA CCGGCCCATC TTACTACCTC CAAGAGTGCT 
TTTCTCTCTA ATAAGAAAAC ATCTACTTTG AAACATCTAC TGGGCGAGAC CAGGAGTGAT 
GGCTCAGCCT GTAATTCTGG AATTTCGGGA GGCCGAGGCA GGAAGATTCC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRAC1 ( NM_032391.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_115767.1 Homo sapiens PRAC1 small nuclear protein (PRAC1), mRNA.

Price & Availability↑

CloneID	OHu25952
Clone ID Related Accession (Same CDS sequence)	NM_032391.2 , NM_032391.3
Accession Version	NM_032391.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 174bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	small nuclear protein PRAC1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF331165.1 and BC030950.1. On Nov 22, 2018 this sequence version replaced NM_032391.2. ##Evidence-Data-START## Transcript exon combination :: CF124750.1, AF331165.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000290294.5/ ENSP00000290294.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

1
61
121

ATGTTGTGCG CCCATTTCTC AGATCAAGGA CCGGCCCATC TTACTACCTC CAAGAGTGCT 
TTTCTCTCTA ATAAGAAAAC ATCTACTTTG AAACATCTAC TGGGCGAGAC CAGGAGTGAT 
GGCTCAGCCT GTAATTCTGG AATTTCGGGA GGCCGAGGCA GGAAGATTCC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115767.1
CDS	127..300
Translation	MLCAHFSDQGPAHLTTSKSAFLSNKKTSTLKHLLGETRSDGSACNSGISGGRGRKIP

Target ORF information:

RefSeq Version	NM_032391.3
Organism	Homo sapiens(human)
Definition	Homo sapiens PRAC1 small nuclear protein (PRAC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032391.3

ORF Insert Sequence:

1
61
121

ATGTTGTGCG CCCATTTCTC AGATCAAGGA CCGGCCCATC TTACTACCTC CAAGAGTGCT 
TTTCTCTCTA ATAAGAAAAC ATCTACTTTG AAACATCTAC TGGGCGAGAC CAGGAGTGAT 
GGCTCAGCCT GTAATTCTGG AATTTCGGGA GGCCGAGGCA GGAAGATTCC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clinical Implications and Prognostic Values of Prostate Cancer Susceptibility Candidate Methylation in Primary Nonmuscle Invasive Bladder Cancer.
Disease markers2015402963(2015)
Kim YW,Yoon HY,Seo SP,Lee SK,Kang HW,Kim WT,Bang HJ,Ryu DH,Yun SJ,Lee SC,Kim WJ,Kim YJ

Aberrant expression of the PRAC gene in prostate cancer.
International journal of oncology43(6)1960-6(2013 Dec)
Lenka G,Weng WH,Chuang CK,Ng KF,Pang ST

PRAC: A novel small nuclear protein that is specifically expressed in human prostate and colon.
The Prostate47(2)125-31(2001 May)
Liu XF,Olsson P,Wolfgang CD,Bera TK,Duray P,Lee B,Pastan I