TMEM63C cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMEM63C
Entrez Gene ID	57156
Full Name	transmembrane protein 63C
Synonyms	C14orf171,CSC1,hsCSC1
General protein information	Preferred Names transmembrane protein 63C Names calcium permeable stress-gated cation channel 1 calcium permeable stress-gated cation channel 1 homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q24.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_020431.4	NP_065164.2	calcium permeable stress-gated cation channel 1
NM_020431.3	NP_065164.2	calcium permeable stress-gated cation channel 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TMEM63C	NP_065164.2
Xenopus tropicalis (tropical clawed frog)	tmem63c	NP_001090668.1
	TMEM63C	XP_002805206.1
Gallus gallus (chicken)	TMEM63C	XP_421286.1
Danio rerio (zebrafish)	LOC100000800	NP_001153308.1
Pan troglodytes (chimpanzee)	TMEM63C	XP_003314510.1
Mus musculus (house mouse)	Tmem63c	NP_766171.1
Rattus norvegicus (Norway rat)	Tmem63c	NP_001101515.1
Canis lupus familiaris (dog)	TMEM63C	XP_005623759.1
Bos taurus (cattle)	TMEM63C	NP_001193090.1

Gene Ontology
Bibliography

Related articles in PubMed

Co-expression of mouse TMEM63A, TMEM63B and TMEM63C confers hyperosmolarity activated ion currents in HEK293 cells.
Zhao X, Yan X, Liu Y, Zhang P, Ni X
Cell biochemistry and function34(4)238-41(2016 Jun)

DUF221 proteins are a family of osmosensitive calcium-permeable cation channels conserved across eukaryotes.
Hou C, Tian W, Kleist T, He K, Garcia V, Bai F, Hao Y, Luan S, Li L
Cell research24(5)632-5(2014 May)

A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder.
Lee HJ, Woo HG, Greenwood TA, Kripke DF, Kelsoe JR
Journal of affective disorders145(2)200-7(2013 Feb)

The DNA sequence and analysis of human chromosome 14.
Heilig R, Eckenberg R, Petit JL, Fonknechten N, Da Silva C, Cattolico L, Levy M, Barbe V, de Berardinis V, Ureta-Vidal A, Pelletier E, Vico V, Anthouard V, Rowen L, Madan A, Qin S, Sun H, Du H, Pepin K, Artiguenave F, Robert C, Cruaud C, Br?ls T, Jaillon O, Friedlander L, Samson G, Brottier P, Cure S, S?gurens B, Ani?re F, Samain S, Crespeau H, Abbasi N, Aiach N, Boscus D, Dickhoff R, Dors M, Dubois I, Friedman C, Gouyvenoux M, James R, Madan A, Mairey-Estrada B, Mangenot S, Martins N, M?nard M, Oztas S, Ratcliffe A, Shaffer T, Trask B, Vacherie B, Bellemere C, Belser C, Besnard-Gonnet M, Bartol-Mavel D, Boutard M, Briez-Silla S, Combette S, Dufoss?-Laurent V, Ferron C, Lechaplais C, Louesse C, Muselet D, Magdelenat G, Pateau E, Petit E, Sirvain-Trukniewicz P, Trybou A, Vega-Czarny N, Bataille E, Bluet E, Bordelais I, Dubois M, Dumont C, Gu?rin T, Haffray S, Hammadi R, Muanga J, Pellouin V, Robert D, Wunderle E, Gauguet G, Roy A, Sainte-Marthe L, Verdier J, Verdier-Discala C, Hillier L, Fulton L, McPherson J, Matsuda F, Wilson R, Scarpelli C, Gyapay G, Wincker P, Saurin W, Qu?tier F, Waterston R, Hood L, Weissenbach J
Nature421(6923)601-7(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following TMEM63C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMEM63C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27782	NM_020431.4 Latest version!	Homo sapiens transmembrane protein 63C (TMEM63C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu27782	NM_020431.3	Homo sapiens transmembrane protein 63C (TMEM63C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMEM63C ( NM_020431.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_065164.2 Homo sapiens transmembrane protein 63C (TMEM63C), mRNA.

Price & Availability↑

CloneID	OHu27782
Clone ID Related Accession (Same CDS sequence)	NM_020431.4 , NM_020431.3
Accession Version	NM_020431.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2421bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	calcium permeable stress-gated cation channel 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL537279.3, AK125159.1, BC136613.1, KF455952.1, AC007375.6, BX248759.1 and AL137278.1. On Nov 22, 2018 this sequence version replaced NM_020431.3. ##Evidence-Data-START## Transcript exon combination :: AK125159.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000298351.5/ ENSP00000298351.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCTGCCT CACCAGACGA CCTGAGTACA GGGGGAAGGT TACAGAACAT GACAGTGGAT 
GAATGCTTCC AGTCTCGGAA CACCGTCCTC CAGGGGCAGC CCTTTGGGGG TGTCCCCACC 
GTGCTGTGCC TCAACATCGC CCTGTGGGTG CTCGTCCTTG TGGTTTACTC CTTCCTCCGG 
AAAGCTGCGT GGGACTATGG GCGCCTGGCT CTGCTGATAC ACAATGACAG CCTGACCTCG 
CTGATCTATG GGGAGCAGAG CGAGAAGACA TCTCCCTCGG AGACTTCCTT GGAGATGGAA 
CGCAGAGACA AGGGATTCTG TTCCTGGTTC TTCAACAGCA TAACAATGAA GGACGAGGAT 
CTGATTAACA AGTGTGGGGA CGACGCGCGC ATCTACATCG TGTTCCAGTA CCACCTCATC 
ATCTTTGTGC TCATCATCTG TATCCCCTCC CTGGGCATCA TTTTGCCCAT CAACTATACT 
GGATCTGTTC TGGACTGGAG CAGTCACTTT GCTCGGACCA CCATTGTCAA TGTCTCCACA 
GAGAGCAAGC TCCTGTGGCT GCATAGCCTG CTGTCCTTCT TCTACTTCAT CACCAACTTC 
ATGTTCATGG CTCATCACTG CCTGGGGTTT GCACCCAGGA ATAGCCAAAA GGTCACAAGG 
ACACTAATGA TCACCTATGT GCCCAAGGAC ATTGAAGACC CAGAACTCAT CATTAAGCAT 
TTTCACGAGG CCTATCCAGG CAGTGTCGTG ACAAGAGTCC ACTTCTGCTA CGACGTCAGG 
AACCTGATCG ACTTGGACGA TCAGAGGCGC CATGCCATGC GGGGCCGGCT TTTCTATACA 
GCCAAGGCCA AGAAGACTGG GAAGGTGATG ATCAGGATCC ACCCCTGTGC CCGCCTGTGC 
TTCTGCAAGT GCTGGACCTG CTTCAAGGAG GTGGATGCAG AGCAGTATTA CAGCGAGCTA 
GAGGAGCAGC TAACGGACGA GTTCAACGCC GAGCTCAACC GCGTGCCGCT CAAGCGGCTG 
GACCTGATCT TTGTCACCTT CCAGGACTCC AGGATGGCCA AGCGTGTCCG TAAGGATTAC 
AAGTATGTCC AGTGTGGTGT GCAACCCCAG CAGTCCTCAG TGACCACCAT CGTCAAATCA 
TATTACTGGA GGGTCACTAT GGCCCCACAC CCCAAAGACA TTATTTGGAA ACACCTGTCT 
GTCCGCCGCT TCTTTTGGTG GGCCCGCTTT ATCGCAATCA ACACCTTCCT CTTCTTCCTC 
TTCTTCTTTC TCACCACGCC TGCCATCATC ATGAACACTA TCGACATGTA CAACGTCACC 
CGCCCCATCG AGAAGCTGCA GAACCCAATT GTGACCCAGT TCTTCCCCTC TGTGATGCTC 
TGGGGCTTCA CAGTGATACT GCCTCTGATT GTCTACTTCT CCGCCTTCCT CGAGGCCCAC 
TGGACCAGAT CAAGTCAGAA TCTGGTCATG GTGCACAAGT GCTACATCTT TCTGGTGTTC 
ATGGTAGTCA TTCTGCCCTC TATGGGACTG ACCAGTTTGG ATGTCTTTCT CCGCTGGCTC 
TTTGACATCT ACTATCTAGA GCAAGCATCC ATCAGGTTCC AGTGTGTGTT CCTGCCAGAC 
AACGGCGCCT TCTTTGTCAA CTACGTGATC ACGGCAGCTT TACTTGGCAC AGGCATGGAG 
CTGCTGCGTC TGGGGTCACT CTTCTGCTAC AGCACCCGCC TCTTCTTCTC TAGATCAGAG 
CCAGAGAGAG TCAACATCAG AAAGAACCAG GCCATAGACT TCCAGTTTGG GCGTGAGTAT 
GCGTGGATGA TGAACGTGTT CAGCGTGGTG ATGGCGTACA GCATCACTTG CCCCATCATT 
GTGCCTTTTG GGTTGCTCTA CCTGTGCATG AAGCACTTGA CGGATCGCTA TAACATGTAC 
TACTCCTTTG CACCCACCAA ACTGAACGAG CAGATCCACA TGGCTGCCGT CTCCCAGGCC 
ATCTTTGCGC CACTCTTGGG TCTGTTCTGG ATGCTGTTCT TCTCCATCCT GCGGTTGGGT 
TCTCTCCACG CCATCACCAT CTTTTCCCTG TCCACCCTCC TCATTGCCAT GGTGATTGCC 
TTTGTTGGCA TTTTTCTGGG GAAGCTTCGG ATGGTTGCCG ACTACGAGCC CGAGGAGGAG 
GAGATCCAGA CAGTGTTTGA CATGGAGCCA AGCAGCACCT CCTCCACGCC CACCTCCCTC 
CTGTATGTGG CCACCGTGCT GCAAGAACCG GAGTTGAATC TGACCCCCGC CTCCTCCCCA 
GCCAGGCACA CCTATGGCAC CATGAACAAC CAGCCGGAAG AGGGAGAAGA AGAGAGTGGT 
CTGAGGGGCT TTGCGAGGGA GCTAGACTCG GCCCAGTTCC AGGAAGGGCT GGAACTGGAG 
GGCCAGAACC AGTACCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065164.2
CDS	174..2594
Translation	MSASPDDLSTGGRLQNMTVDECFQSRNTVLQGQPFGGVPTVLCLNIALWVLVLVVYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKTSPSETSLEMERRDKGFCSWFFNSITMKDEDLINKCGDDARIYIVFQYHLIIFVLIICIPSLGIILPINYTGSVLDWSSHFARTTIVNVSTESKLLWLHSLLSFFYFITNFMFMAHHCLGFAPRNSQKVTRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYDVRNLIDLDDQRRHAMRGRLFYTAKAKKTGKVMIRIHPCARLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELNRVPLKRLDLIFVTFQDSRMAKRVRKDYKYVQCGVQPQQSSVTTIVKSYYWRVTMAPHPKDIIWKHLSVRRFFWWARFIAINTFLFFLFFFLTTPAIIMNTIDMYNVTRPIEKLQNPIVTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVHKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITAALLGTGMELLRLGSLFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHLTDRYNMYYSFAPTKLNEQIHMAAVSQAIFAPLLGLFWMLFFSILRLGSLHAITIFSLSTLLIAMVIAFVGIFLGKLRMVADYEPEEEEIQTVFDMEPSSTSSTPTSLLYVATVLQEPELNLTPASSPARHTYGTMNNQPEEGEEESGLRGFARELDSAQFQEGLELEGQNQYH

Target ORF information:

RefSeq Version	NM_020431.4
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 63C (TMEM63C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020431.4

ORF Insert Sequence:

ATGTCTGCCT CACCAGACGA CCTGAGTACA GGGGGAAGGT TACAGAACAT GACAGTGGAT 
GAATGCTTCC AGTCTCGGAA CACCGTCCTC CAGGGGCAGC CCTTTGGGGG TGTCCCCACC 
GTGCTGTGCC TCAACATCGC CCTGTGGGTG CTCGTCCTTG TGGTTTACTC CTTCCTCCGG 
AAAGCTGCGT GGGACTATGG GCGCCTGGCT CTGCTGATAC ACAATGACAG CCTGACCTCG 
CTGATCTATG GGGAGCAGAG CGAGAAGACA TCTCCCTCGG AGACTTCCTT GGAGATGGAA 
CGCAGAGACA AGGGATTCTG TTCCTGGTTC TTCAACAGCA TAACAATGAA GGACGAGGAT 
CTGATTAACA AGTGTGGGGA CGACGCGCGC ATCTACATCG TGTTCCAGTA CCACCTCATC 
ATCTTTGTGC TCATCATCTG TATCCCCTCC CTGGGCATCA TTTTGCCCAT CAACTATACT 
GGATCTGTTC TGGACTGGAG CAGTCACTTT GCTCGGACCA CCATTGTCAA TGTCTCCACA 
GAGAGCAAGC TCCTGTGGCT GCATAGCCTG CTGTCCTTCT TCTACTTCAT CACCAACTTC 
ATGTTCATGG CTCATCACTG CCTGGGGTTT GCACCCAGGA ATAGCCAAAA GGTCACAAGG 
ACACTAATGA TCACCTATGT GCCCAAGGAC ATTGAAGACC CAGAACTCAT CATTAAGCAT 
TTTCACGAGG CCTATCCAGG CAGTGTCGTG ACAAGAGTCC ACTTCTGCTA CGACGTCAGG 
AACCTGATCG ACTTGGACGA TCAGAGGCGC CATGCCATGC GGGGCCGGCT TTTCTATACA 
GCCAAGGCCA AGAAGACTGG GAAGGTGATG ATCAGGATCC ACCCCTGTGC CCGCCTGTGC 
TTCTGCAAGT GCTGGACCTG CTTCAAGGAG GTGGATGCAG AGCAGTATTA CAGCGAGCTA 
GAGGAGCAGC TAACGGACGA GTTCAACGCC GAGCTCAACC GCGTGCCGCT CAAGCGGCTG 
GACCTGATCT TTGTCACCTT CCAGGACTCC AGGATGGCCA AGCGTGTCCG TAAGGATTAC 
AAGTATGTCC AGTGTGGTGT GCAACCCCAG CAGTCCTCAG TGACCACCAT CGTCAAATCA 
TATTACTGGA GGGTCACTAT GGCCCCACAC CCCAAAGACA TTATTTGGAA ACACCTGTCT 
GTCCGCCGCT TCTTTTGGTG GGCCCGCTTT ATCGCAATCA ACACCTTCCT CTTCTTCCTC 
TTCTTCTTTC TCACCACGCC TGCCATCATC ATGAACACTA TCGACATGTA CAACGTCACC 
CGCCCCATCG AGAAGCTGCA GAACCCAATT GTGACCCAGT TCTTCCCCTC TGTGATGCTC 
TGGGGCTTCA CAGTGATACT GCCTCTGATT GTCTACTTCT CCGCCTTCCT CGAGGCCCAC 
TGGACCAGAT CAAGTCAGAA TCTGGTCATG GTGCACAAGT GCTACATCTT TCTGGTGTTC 
ATGGTAGTCA TTCTGCCCTC TATGGGACTG ACCAGTTTGG ATGTCTTTCT CCGCTGGCTC 
TTTGACATCT ACTATCTAGA GCAAGCATCC ATCAGGTTCC AGTGTGTGTT CCTGCCAGAC 
AACGGCGCCT TCTTTGTCAA CTACGTGATC ACGGCAGCTT TACTTGGCAC AGGCATGGAG 
CTGCTGCGTC TGGGGTCACT CTTCTGCTAC AGCACCCGCC TCTTCTTCTC TAGATCAGAG 
CCAGAGAGAG TCAACATCAG AAAGAACCAG GCCATAGACT TCCAGTTTGG GCGTGAGTAT 
GCGTGGATGA TGAACGTGTT CAGCGTGGTG ATGGCGTACA GCATCACTTG CCCCATCATT 
GTGCCTTTTG GGTTGCTCTA CCTGTGCATG AAGCACTTGA CGGATCGCTA TAACATGTAC 
TACTCCTTTG CACCCACCAA ACTGAACGAG CAGATCCACA TGGCTGCCGT CTCCCAGGCC 
ATCTTTGCGC CACTCTTGGG TCTGTTCTGG ATGCTGTTCT TCTCCATCCT GCGGTTGGGT 
TCTCTCCACG CCATCACCAT CTTTTCCCTG TCCACCCTCC TCATTGCCAT GGTGATTGCC 
TTTGTTGGCA TTTTTCTGGG GAAGCTTCGG ATGGTTGCCG ACTACGAGCC CGAGGAGGAG 
GAGATCCAGA CAGTGTTTGA CATGGAGCCA AGCAGCACCT CCTCCACGCC CACCTCCCTC 
CTGTATGTGG CCACCGTGCT GCAAGAACCG GAGTTGAATC TGACCCCCGC CTCCTCCCCA 
GCCAGGCACA CCTATGGCAC CATGAACAAC CAGCCGGAAG AGGGAGAAGA AGAGAGTGGT 
CTGAGGGGCT TTGCGAGGGA GCTAGACTCG GCCCAGTTCC AGGAAGGGCT GGAACTGGAG 
GGCCAGAACC AGTACCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM63C ( NM_020431.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_065164.2 Homo sapiens transmembrane protein 63C (TMEM63C), mRNA.

Price & Availability↑

CloneID	OHu27782
Clone ID Related Accession (Same CDS sequence)	NM_020431.4 , NM_020431.3
Accession Version	NM_020431.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2421bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-22
Organism	Homo sapiens(human)
Product	calcium permeable stress-gated cation channel 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL537279.3, AK125159.1, BC136613.1, KF455952.1, AC007375.6, BX248759.1 and AL137278.1. On Jan 17, 2014 this sequence version replaced NM_020431.2. ##Evidence-Data-START## Transcript exon combination :: AK125159.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743 [ECO:0000348] ##Evidence-Data-END##

ATGTCTGCCT CACCAGACGA CCTGAGTACA GGGGGAAGGT TACAGAACAT GACAGTGGAT 
GAATGCTTCC AGTCTCGGAA CACCGTCCTC CAGGGGCAGC CCTTTGGGGG TGTCCCCACC 
GTGCTGTGCC TCAACATCGC CCTGTGGGTG CTCGTCCTTG TGGTTTACTC CTTCCTCCGG 
AAAGCTGCGT GGGACTATGG GCGCCTGGCT CTGCTGATAC ACAATGACAG CCTGACCTCG 
CTGATCTATG GGGAGCAGAG CGAGAAGACA TCTCCCTCGG AGACTTCCTT GGAGATGGAA 
CGCAGAGACA AGGGATTCTG TTCCTGGTTC TTCAACAGCA TAACAATGAA GGACGAGGAT 
CTGATTAACA AGTGTGGGGA CGACGCGCGC ATCTACATCG TGTTCCAGTA CCACCTCATC 
ATCTTTGTGC TCATCATCTG TATCCCCTCC CTGGGCATCA TTTTGCCCAT CAACTATACT 
GGATCTGTTC TGGACTGGAG CAGTCACTTT GCTCGGACCA CCATTGTCAA TGTCTCCACA 
GAGAGCAAGC TCCTGTGGCT GCATAGCCTG CTGTCCTTCT TCTACTTCAT CACCAACTTC 
ATGTTCATGG CTCATCACTG CCTGGGGTTT GCACCCAGGA ATAGCCAAAA GGTCACAAGG 
ACACTAATGA TCACCTATGT GCCCAAGGAC ATTGAAGACC CAGAACTCAT CATTAAGCAT 
TTTCACGAGG CCTATCCAGG CAGTGTCGTG ACAAGAGTCC ACTTCTGCTA CGACGTCAGG 
AACCTGATCG ACTTGGACGA TCAGAGGCGC CATGCCATGC GGGGCCGGCT TTTCTATACA 
GCCAAGGCCA AGAAGACTGG GAAGGTGATG ATCAGGATCC ACCCCTGTGC CCGCCTGTGC 
TTCTGCAAGT GCTGGACCTG CTTCAAGGAG GTGGATGCAG AGCAGTATTA CAGCGAGCTA 
GAGGAGCAGC TAACGGACGA GTTCAACGCC GAGCTCAACC GCGTGCCGCT CAAGCGGCTG 
GACCTGATCT TTGTCACCTT CCAGGACTCC AGGATGGCCA AGCGTGTCCG TAAGGATTAC 
AAGTATGTCC AGTGTGGTGT GCAACCCCAG CAGTCCTCAG TGACCACCAT CGTCAAATCA 
TATTACTGGA GGGTCACTAT GGCCCCACAC CCCAAAGACA TTATTTGGAA ACACCTGTCT 
GTCCGCCGCT TCTTTTGGTG GGCCCGCTTT ATCGCAATCA ACACCTTCCT CTTCTTCCTC 
TTCTTCTTTC TCACCACGCC TGCCATCATC ATGAACACTA TCGACATGTA CAACGTCACC 
CGCCCCATCG AGAAGCTGCA GAACCCAATT GTGACCCAGT TCTTCCCCTC TGTGATGCTC 
TGGGGCTTCA CAGTGATACT GCCTCTGATT GTCTACTTCT CCGCCTTCCT CGAGGCCCAC 
TGGACCAGAT CAAGTCAGAA TCTGGTCATG GTGCACAAGT GCTACATCTT TCTGGTGTTC 
ATGGTAGTCA TTCTGCCCTC TATGGGACTG ACCAGTTTGG ATGTCTTTCT CCGCTGGCTC 
TTTGACATCT ACTATCTAGA GCAAGCATCC ATCAGGTTCC AGTGTGTGTT CCTGCCAGAC 
AACGGCGCCT TCTTTGTCAA CTACGTGATC ACGGCAGCTT TACTTGGCAC AGGCATGGAG 
CTGCTGCGTC TGGGGTCACT CTTCTGCTAC AGCACCCGCC TCTTCTTCTC TAGATCAGAG 
CCAGAGAGAG TCAACATCAG AAAGAACCAG GCCATAGACT TCCAGTTTGG GCGTGAGTAT 
GCGTGGATGA TGAACGTGTT CAGCGTGGTG ATGGCGTACA GCATCACTTG CCCCATCATT 
GTGCCTTTTG GGTTGCTCTA CCTGTGCATG AAGCACTTGA CGGATCGCTA TAACATGTAC 
TACTCCTTTG CACCCACCAA ACTGAACGAG CAGATCCACA TGGCTGCCGT CTCCCAGGCC 
ATCTTTGCGC CACTCTTGGG TCTGTTCTGG ATGCTGTTCT TCTCCATCCT GCGGTTGGGT 
TCTCTCCACG CCATCACCAT CTTTTCCCTG TCCACCCTCC TCATTGCCAT GGTGATTGCC 
TTTGTTGGCA TTTTTCTGGG GAAGCTTCGG ATGGTTGCCG ACTACGAGCC CGAGGAGGAG 
GAGATCCAGA CAGTGTTTGA CATGGAGCCA AGCAGCACCT CCTCCACGCC CACCTCCCTC 
CTGTATGTGG CCACCGTGCT GCAAGAACCG GAGTTGAATC TGACCCCCGC CTCCTCCCCA 
GCCAGGCACA CCTATGGCAC CATGAACAAC CAGCCGGAAG AGGGAGAAGA AGAGAGTGGT 
CTGAGGGGCT TTGCGAGGGA GCTAGACTCG GCCCAGTTCC AGGAAGGGCT GGAACTGGAG 
GGCCAGAACC AGTACCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065164.2
CDS	213..2633
Translation	MSASPDDLSTGGRLQNMTVDECFQSRNTVLQGQPFGGVPTVLCLNIALWVLVLVVYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKTSPSETSLEMERRDKGFCSWFFNSITMKDEDLINKCGDDARIYIVFQYHLIIFVLIICIPSLGIILPINYTGSVLDWSSHFARTTIVNVSTESKLLWLHSLLSFFYFITNFMFMAHHCLGFAPRNSQKVTRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYDVRNLIDLDDQRRHAMRGRLFYTAKAKKTGKVMIRIHPCARLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELNRVPLKRLDLIFVTFQDSRMAKRVRKDYKYVQCGVQPQQSSVTTIVKSYYWRVTMAPHPKDIIWKHLSVRRFFWWARFIAINTFLFFLFFFLTTPAIIMNTIDMYNVTRPIEKLQNPIVTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVHKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITAALLGTGMELLRLGSLFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHLTDRYNMYYSFAPTKLNEQIHMAAVSQAIFAPLLGLFWMLFFSILRLGSLHAITIFSLSTLLIAMVIAFVGIFLGKLRMVADYEPEEEEIQTVFDMEPSSTSSTPTSLLYVATVLQEPELNLTPASSPARHTYGTMNNQPEEGEEESGLRGFARELDSAQFQEGLELEGQNQYH

Target ORF information:

RefSeq Version	NM_020431.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 63C (TMEM63C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020431.3

ORF Insert Sequence:

ATGTCTGCCT CACCAGACGA CCTGAGTACA GGGGGAAGGT TACAGAACAT GACAGTGGAT 
GAATGCTTCC AGTCTCGGAA CACCGTCCTC CAGGGGCAGC CCTTTGGGGG TGTCCCCACC 
GTGCTGTGCC TCAACATCGC CCTGTGGGTG CTCGTCCTTG TGGTTTACTC CTTCCTCCGG 
AAAGCTGCGT GGGACTATGG GCGCCTGGCT CTGCTGATAC ACAATGACAG CCTGACCTCG 
CTGATCTATG GGGAGCAGAG CGAGAAGACA TCTCCCTCGG AGACTTCCTT GGAGATGGAA 
CGCAGAGACA AGGGATTCTG TTCCTGGTTC TTCAACAGCA TAACAATGAA GGACGAGGAT 
CTGATTAACA AGTGTGGGGA CGACGCGCGC ATCTACATCG TGTTCCAGTA CCACCTCATC 
ATCTTTGTGC TCATCATCTG TATCCCCTCC CTGGGCATCA TTTTGCCCAT CAACTATACT 
GGATCTGTTC TGGACTGGAG CAGTCACTTT GCTCGGACCA CCATTGTCAA TGTCTCCACA 
GAGAGCAAGC TCCTGTGGCT GCATAGCCTG CTGTCCTTCT TCTACTTCAT CACCAACTTC 
ATGTTCATGG CTCATCACTG CCTGGGGTTT GCACCCAGGA ATAGCCAAAA GGTCACAAGG 
ACACTAATGA TCACCTATGT GCCCAAGGAC ATTGAAGACC CAGAACTCAT CATTAAGCAT 
TTTCACGAGG CCTATCCAGG CAGTGTCGTG ACAAGAGTCC ACTTCTGCTA CGACGTCAGG 
AACCTGATCG ACTTGGACGA TCAGAGGCGC CATGCCATGC GGGGCCGGCT TTTCTATACA 
GCCAAGGCCA AGAAGACTGG GAAGGTGATG ATCAGGATCC ACCCCTGTGC CCGCCTGTGC 
TTCTGCAAGT GCTGGACCTG CTTCAAGGAG GTGGATGCAG AGCAGTATTA CAGCGAGCTA 
GAGGAGCAGC TAACGGACGA GTTCAACGCC GAGCTCAACC GCGTGCCGCT CAAGCGGCTG 
GACCTGATCT TTGTCACCTT CCAGGACTCC AGGATGGCCA AGCGTGTCCG TAAGGATTAC 
AAGTATGTCC AGTGTGGTGT GCAACCCCAG CAGTCCTCAG TGACCACCAT CGTCAAATCA 
TATTACTGGA GGGTCACTAT GGCCCCACAC CCCAAAGACA TTATTTGGAA ACACCTGTCT 
GTCCGCCGCT TCTTTTGGTG GGCCCGCTTT ATCGCAATCA ACACCTTCCT CTTCTTCCTC 
TTCTTCTTTC TCACCACGCC TGCCATCATC ATGAACACTA TCGACATGTA CAACGTCACC 
CGCCCCATCG AGAAGCTGCA GAACCCAATT GTGACCCAGT TCTTCCCCTC TGTGATGCTC 
TGGGGCTTCA CAGTGATACT GCCTCTGATT GTCTACTTCT CCGCCTTCCT CGAGGCCCAC 
TGGACCAGAT CAAGTCAGAA TCTGGTCATG GTGCACAAGT GCTACATCTT TCTGGTGTTC 
ATGGTAGTCA TTCTGCCCTC TATGGGACTG ACCAGTTTGG ATGTCTTTCT CCGCTGGCTC 
TTTGACATCT ACTATCTAGA GCAAGCATCC ATCAGGTTCC AGTGTGTGTT CCTGCCAGAC 
AACGGCGCCT TCTTTGTCAA CTACGTGATC ACGGCAGCTT TACTTGGCAC AGGCATGGAG 
CTGCTGCGTC TGGGGTCACT CTTCTGCTAC AGCACCCGCC TCTTCTTCTC TAGATCAGAG 
CCAGAGAGAG TCAACATCAG AAAGAACCAG GCCATAGACT TCCAGTTTGG GCGTGAGTAT 
GCGTGGATGA TGAACGTGTT CAGCGTGGTG ATGGCGTACA GCATCACTTG CCCCATCATT 
GTGCCTTTTG GGTTGCTCTA CCTGTGCATG AAGCACTTGA CGGATCGCTA TAACATGTAC 
TACTCCTTTG CACCCACCAA ACTGAACGAG CAGATCCACA TGGCTGCCGT CTCCCAGGCC 
ATCTTTGCGC CACTCTTGGG TCTGTTCTGG ATGCTGTTCT TCTCCATCCT GCGGTTGGGT 
TCTCTCCACG CCATCACCAT CTTTTCCCTG TCCACCCTCC TCATTGCCAT GGTGATTGCC 
TTTGTTGGCA TTTTTCTGGG GAAGCTTCGG ATGGTTGCCG ACTACGAGCC CGAGGAGGAG 
GAGATCCAGA CAGTGTTTGA CATGGAGCCA AGCAGCACCT CCTCCACGCC CACCTCCCTC 
CTGTATGTGG CCACCGTGCT GCAAGAACCG GAGTTGAATC TGACCCCCGC CTCCTCCCCA 
GCCAGGCACA CCTATGGCAC CATGAACAAC CAGCCGGAAG AGGGAGAAGA AGAGAGTGGT 
CTGAGGGGCT TTGCGAGGGA GCTAGACTCG GCCCAGTTCC AGGAAGGGCT GGAACTGGAG 
GGCCAGAACC AGTACCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Co-expression of mouse TMEM63A, TMEM63B and TMEM63C confers hyperosmolarity activated ion currents in HEK293 cells.
Cell biochemistry and function34(4)238-41(2016 Jun)
Zhao X,Yan X,Liu Y,Zhang P,Ni X

DUF221 proteins are a family of osmosensitive calcium-permeable cation channels conserved across eukaryotes.
Cell research24(5)632-5(2014 May)
Hou C,Tian W,Kleist T,He K,Garcia V,Bai F,Hao Y,Luan S,Li L

A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder.
Journal of affective disorders145(2)200-7(2013 Feb)
Lee HJ,Woo HG,Greenwood TA,Kripke DF,Kelsoe JR

The DNA sequence and analysis of human chromosome 14.
Nature421(6923)601-7(2003 Feb)
Heilig R,Eckenberg R,Petit JL,Fonknechten N,Da Silva C,Cattolico L,Levy M,Barbe V,de Berardinis V,Ureta-Vidal A,Pelletier E,Vico V,Anthouard V,Rowen L,Madan A,Qin S,Sun H,Du H,Pepin K,Artiguenave F,Robert C,Cruaud C,Br?ls T,Jaillon O,Friedlander L,Samson G,Brottier P,Cure S,S?gurens B,Ani?re F,Samain S,Crespeau H,Abbasi N,Aiach N,Boscus D,Dickhoff R,Dors M,Dubois I,Friedman C,Gouyvenoux M,James R,Madan A,Mairey-Estrada B,Mangenot S,Martins N,M?nard M,Oztas S,Ratcliffe A,Shaffer T,Trask B,Vacherie B,Bellemere C,Belser C,Besnard-Gonnet M,Bartol-Mavel D,Boutard M,Briez-Silla S,Combette S,Dufoss?-Laurent V,Ferron C,Lechaplais C,Louesse C,Muselet D,Magdelenat G,Pateau E,Petit E,Sirvain-Trukniewicz P,Trybou A,Vega-Czarny N,Bataille E,Bluet E,Bordelais I,Dubois M,Dumont C,Gu?rin T,Haffray S,Hammadi R,Muanga J,Pellouin V,Robert D,Wunderle E,Gauguet G,Roy A,Sainte-Marthe L,Verdier J,Verdier-Discala C,Hillier L,Fulton L,McPherson J,Matsuda F,Wilson R,Scarpelli C,Gyapay G,Wincker P,Saurin W,Qu?tier F,Waterston R,Hood L,Weissenbach J

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TMEM63C cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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