AK3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	AK3
Entrez Gene ID	50808
Full Name	adenylate kinase 3
Synonyms	AK3L1,AK6,AKL3L,AKL3L1,FIX
General protein information	Preferred Names adenylate kinase 3 Names GTP:AMP phosphotransferase AK3, mitochondrial GTP:AMP phosphotransferase, mitochondrial adenylate kinase 3 alpha-like 1 adenylate kinase 6, adenylate kinase 3 like 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9p24.1
Summary	The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2010].
Disorder MIM:	609290

mRNA and Protein(s)

mRNA	Protein	Name
NM_001199855.1	NP_001186784.1	GTP:AMP phosphotransferase AK3, mitochondrial isoform c
NM_001199856.1	NP_001186785.1	GTP:AMP phosphotransferase AK3, mitochondrial isoform c
NM_001199852.2	NP_001186781.1	GTP:AMP phosphotransferase AK3, mitochondrial isoform b
NM_001199853.1	NP_001186782.1	GTP:AMP phosphotransferase AK3, mitochondrial isoform c
NM_016282.4	NP_057366.2	GTP:AMP phosphotransferase AK3, mitochondrial isoform a
NM_001199852.1	NP_001186781.1	GTP:AMP phosphotransferase AK3, mitochondrial isoform b
NM_016282.3	NP_057366.2	GTP:AMP phosphotransferase AK3, mitochondrial isoform a

Pathways from BioSystems

Homologies

	AK3	XP_001084982.1
Canis lupus familiaris (dog)	LOC100856042	XP_003639300.2
Mus musculus (house mouse)	Ak3	NP_067274.1
Rattus norvegicus (Norway rat)	Ak3	NP_037350.1
Gallus gallus (chicken)	AK3	XP_424173.4
Saccharomyces cerevisiae (baker's yeast)	ADK2	NP_011097.3
Homo sapiens (human)	AK3	NP_057366.2
Canis lupus familiaris (dog)	LOC102152410	XP_005637490.1
Caenorhabditis elegans (roundworm)	CELE_ZK673.2	NP_496245.1
Pan troglodytes (chimpanzee)	AK3	XP_001138039.2
Canis lupus familiaris (dog)	LOC480491	XP_005624284.1
Bos taurus (cattle)	AK3	NP_776662.1
Drosophila melanogaster (fruit fly)	Adk3	NP_524312.1
Kluyveromyces lactis	KLLA0C17754g	XP_452993.1
Neurospora crassa	NCU03216	XP_965316.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009660	XP_318704.4
Eremothecium gossypii	AGOS_AGR115C	NP_986781.1
Magnaporthe oryzae (rice blast fungus)	MGG_03683	XP_003716199.1
Danio rerio (zebrafish)	ak3	NP_998295.2

Gene Ontology
Bibliography

Related articles in PubMed

Candidate predisposing germline copy number variants in early onset colorectal cancer patients.
Brea-Fernandez AJ, Fernandez-Rozadilla C, Alvarez-Barona M, Azuara D, Ginesta MM, Clofent J, de Castro L, Gonzalez D, Andreu M, Bessa X, Llor X, Xicola R, Jover R, Castells A, Castellvi-Bel S, Capella G, Carracedo A, Ruiz-Ponte C
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico19(5)625-632(2017 May)

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
Kenny EE, Pe'er I, Karban A, Ozelius L, Mitchell AA, Ng SM, Erazo M, Ostrer H, Abraham C, Abreu MT, Atzmon G, Barzilai N, Brant SR, Bressman S, Burns ER, Chowers Y, Clark LN, Darvasi A, Doheny D, Duerr RH, Eliakim R, Giladi N, Gregersen PK, Hakonarson H, Jones MR, Marder K, McGovern DP, Mulle J, Orr-Urtreger A, Proctor DD, Pulver A, Rotter JI, Silverberg MS, Ullman T, Warren ST, Waterman M, Zhang W, Bergman A, Mayer L, Katz S, Desnick RJ, Cho JH, Peter I
PLoS genetics8(3)e1002559(2012)

New gene functions in megakaryopoiesis and platelet formation.
Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y, Lopez LM, M?gi R, Meacham S, Okada Y, Pirastu N, Sorice R, Teumer A, Voss K, Zhang W, Ramirez-Solis R, Bis JC, Ellinghaus D, G?gele M, Hottenga JJ, Langenberg C, Kovacs P, O'Reilly PF, Shin SY, Esko T, Hartiala J, Kanoni S, Murgia F, Parsa A, Stephens J, van der Harst P, Ellen van der Schoot C, Allayee H, Attwood A, Balkau B, Bastardot F, Basu S, Baumeister SE, Biino G, Bomba L, Bonnefond A, Cambien F, Chambers JC, Cucca F, D'Adamo P, Davies G, de Boer RA, de Geus EJ, D?ring A, Elliott P, Erdmann J, Evans DM, Falchi M, Feng W, Folsom AR, Frazer IH, Gibson QD, Glazer NL, Hammond C, Hartikainen AL, Heckbert SR, Hengstenberg C, Hersch M, Illig T, Loos RJ, Jolley J, Khaw KT, K?hnel B, Kyrtsonis MC, Lagou V, Lloyd-Jones H, Lumley T, Mangino M, Maschio A, Mateo Leach I, McKnight B, Memari Y, Mitchell BD, Montgomery GW, Nakamura Y, Nauck M, Navis G, N?thlings U, Nolte IM, Porteous DJ, Pouta A, Pramstaller PP, Pullat J, Ring SM, Rotter JI, Ruggiero D, Ruokonen A, Sala C, Samani NJ, Sambrook J, Schlessinger D, Schreiber S, Schunkert H, Scott J, Smith NL, Snieder H, Starr JM, Stumvoll M, Takahashi A, Tang WH, Taylor K, Tenesa A, Lay Thein S, T?njes A, Uda M, Ulivi S, van Veldhuisen DJ, Visscher PM, V?lker U, Wichmann HE, Wiggins KL, Willemsen G, Yang TP, Hua Zhao J, Zitting P, Bradley JR, Dedoussis GV, Gasparini P, Hazen SL, Metspalu A, Pirastu M, Shuldiner AR, Joost van Pelt L, Zwaginga JJ, Boomsma DI, Deary IJ, Franke A, Froguel P, Ganesh SK, Jarvelin MR, Martin NG, Meisinger C, Psaty BM, Spector TD, Wareham NJ, Akkerman JW, Ciullo M, Deloukas P, Greinacher A, Jupe S, Kamatani N, Khadake J, Kooner JS, Penninger J, Prokopenko I, Stemple D, Toniolo D, Wernisch L, Sanna S, Hicks AA, Rendon A, Ferreira MA, Ouwehand WH, Soranzo N
Nature480(7376)201-8(2011 Nov)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

Genome-wide association study of hematological and biochemical traits in a Japanese population.
Kamatani Y, Matsuda K, Okada Y, Kubo M, Hosono N, Daigo Y, Nakamura Y, Kamatani N
Nature genetics42(3)210-5(2010 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings suggest that AK3 and SLIT2 may be potential candidates involved in genetic susceptibility to colorectal cancer
Title: Candidate predisposing germline copy number variants in early onset colorectal cancer patients.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

The following AK3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AK3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu01795	NM_001199856.1 Latest version!	Homo sapiens adenylate kinase 3 (AK3), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu01795	NM_001199853.1 Latest version!	Homo sapiens adenylate kinase 3 (AK3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu01795	NM_001199855.1 Latest version!	Homo sapiens adenylate kinase 3 (AK3), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11261	NM_016282.4 Latest version!	Homo sapiens adenylate kinase 3 (AK3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10745	NM_001199852.2 Latest version!	Homo sapiens adenylate kinase 3 (AK3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu10745	NM_001199852.1	Homo sapiens adenylate kinase 3 (AK3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu11261	NM_016282.3	Homo sapiens adenylate kinase 3 (AK3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AK3 ( NM_001199855.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186784.1 Homo sapiens adenylate kinase 3 (AK3), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu01795
Clone ID Related Accession (Same CDS sequence)	NM_001199855.1 , NM_001199856.1 , NM_001199853.1
Accession Version	NM_001199855.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 474bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	GTP:AMP phosphotransferase AK3, mitochondrial isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA718987.1, AF183419.1, AK001553.1, AL136231.12, AF100785.1 and BX640794.1. Transcript Variant: This variant (5) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Variants 3, 5, and 6 all encode the same isoform (c). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA718987.1, SRR1803617.234928.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACTCGGC TGGCCCTTCA TGAGCTGAAA AATCTCACCC AGTATAGCTG GCTGTTGGAT 
GGTTTTCCAA GGACACTTCC ACAGGCAGAA GCCCTAGATA GAGCTTATCA GATCGACACA 
GTGATTAACC TGAATGTGCC CTTTGAGGTC ATTAAACAAC GCCTTACTGC TCGCTGGATT 
CATCCCGCCA GTGGCCGAGT CTATAACATT GAATTCAACC CTCCCAAAAC TGTGGGCATT 
GATGACCTGA CTGGGGAGCC TCTCATTCAG CGTGAGGATG ATAAACCAGA GACGGTTATC 
AAGAGACTAA AGGCTTATGA AGACCAAACA AAGCCAGTCC TGGAATATTA CCAGAAAAAA 
GGGGTGCTGG AAACATTCTC CGGAACAGAA ACCAACAAGA TTTGGCCCTA TGTATATGCT 
TTCCTACAAA CTAAAGTTCC ACAAAGAAGC CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186784.1
CDS	139..612
Translation	MTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP

Target ORF information:

RefSeq Version	NM_001199855.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 3 (AK3), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199855.1

ORF Insert Sequence:

ATGACTCGGC TGGCCCTTCA TGAGCTGAAA AATCTCACCC AGTATAGCTG GCTGTTGGAT 
GGTTTTCCAA GGACACTTCC ACAGGCAGAA GCCCTAGATA GAGCTTATCA GATCGACACA 
GTGATTAACC TGAATGTGCC CTTTGAGGTC ATTAAACAAC GCCTTACTGC TCGCTGGATT 
CATCCCGCCA GTGGCCGAGT CTATAACATT GAATTCAACC CTCCCAAAAC TGTGGGCATT 
GATGACCTGA CTGGGGAGCC TCTCATTCAG CGTGAGGATG ATAAACCAGA GACGGTTATC 
AAGAGACTAA AGGCTTATGA AGACCAAACA AAGCCAGTCC TGGAATATTA CCAGAAAAAA 
GGGGTGCTGG AAACATTCTC CGGAACAGAA ACCAACAAGA TTTGGCCCTA TGTATATGCT 
TTCCTACAAA CTAAAGTTCC ACAAAGAAGC CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK3 ( NM_001199856.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186785.1 Homo sapiens adenylate kinase 3 (AK3), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu01795
Clone ID Related Accession (Same CDS sequence)	NM_001199855.1 , NM_001199856.1 , NM_001199853.1
Accession Version	NM_001199856.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 474bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	GTP:AMP phosphotransferase AK3, mitochondrial isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA570364.1, AK001553.1, AL136231.12, AF100785.1 and BX640794.1. Transcript Variant: This variant (6) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Variants 3, 5, and 6 all encode the same isoform (c). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.2243.1, SRR1803612.141520.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACTCGGC TGGCCCTTCA TGAGCTGAAA AATCTCACCC AGTATAGCTG GCTGTTGGAT 
GGTTTTCCAA GGACACTTCC ACAGGCAGAA GCCCTAGATA GAGCTTATCA GATCGACACA 
GTGATTAACC TGAATGTGCC CTTTGAGGTC ATTAAACAAC GCCTTACTGC TCGCTGGATT 
CATCCCGCCA GTGGCCGAGT CTATAACATT GAATTCAACC CTCCCAAAAC TGTGGGCATT 
GATGACCTGA CTGGGGAGCC TCTCATTCAG CGTGAGGATG ATAAACCAGA GACGGTTATC 
AAGAGACTAA AGGCTTATGA AGACCAAACA AAGCCAGTCC TGGAATATTA CCAGAAAAAA 
GGGGTGCTGG AAACATTCTC CGGAACAGAA ACCAACAAGA TTTGGCCCTA TGTATATGCT 
TTCCTACAAA CTAAAGTTCC ACAAAGAAGC CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186785.1
CDS	205..678
Translation	MTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP

Target ORF information:

RefSeq Version	NM_001199856.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 3 (AK3), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199856.1

ORF Insert Sequence:

ATGACTCGGC TGGCCCTTCA TGAGCTGAAA AATCTCACCC AGTATAGCTG GCTGTTGGAT 
GGTTTTCCAA GGACACTTCC ACAGGCAGAA GCCCTAGATA GAGCTTATCA GATCGACACA 
GTGATTAACC TGAATGTGCC CTTTGAGGTC ATTAAACAAC GCCTTACTGC TCGCTGGATT 
CATCCCGCCA GTGGCCGAGT CTATAACATT GAATTCAACC CTCCCAAAAC TGTGGGCATT 
GATGACCTGA CTGGGGAGCC TCTCATTCAG CGTGAGGATG ATAAACCAGA GACGGTTATC 
AAGAGACTAA AGGCTTATGA AGACCAAACA AAGCCAGTCC TGGAATATTA CCAGAAAAAA 
GGGGTGCTGG AAACATTCTC CGGAACAGAA ACCAACAAGA TTTGGCCCTA TGTATATGCT 
TTCCTACAAA CTAAAGTTCC ACAAAGAAGC CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK3 ( NM_001199853.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186782.1 Homo sapiens adenylate kinase 3 (AK3), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu01795
Clone ID Related Accession (Same CDS sequence)	NM_001199855.1 , NM_001199856.1 , NM_001199853.1
Accession Version	NM_001199853.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 474bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	GTP:AMP phosphotransferase AK3, mitochondrial isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF183419.1, AK001553.1, AL136231.12, AF100785.1 and BX640794.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Variants 3, 5, and 6 all encode the same isoform (c). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF183419.1, SRR1660807.52576.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACTCGGC TGGCCCTTCA TGAGCTGAAA AATCTCACCC AGTATAGCTG GCTGTTGGAT 
GGTTTTCCAA GGACACTTCC ACAGGCAGAA GCCCTAGATA GAGCTTATCA GATCGACACA 
GTGATTAACC TGAATGTGCC CTTTGAGGTC ATTAAACAAC GCCTTACTGC TCGCTGGATT 
CATCCCGCCA GTGGCCGAGT CTATAACATT GAATTCAACC CTCCCAAAAC TGTGGGCATT 
GATGACCTGA CTGGGGAGCC TCTCATTCAG CGTGAGGATG ATAAACCAGA GACGGTTATC 
AAGAGACTAA AGGCTTATGA AGACCAAACA AAGCCAGTCC TGGAATATTA CCAGAAAAAA 
GGGGTGCTGG AAACATTCTC CGGAACAGAA ACCAACAAGA TTTGGCCCTA TGTATATGCT 
TTCCTACAAA CTAAAGTTCC ACAAAGAAGC CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186782.1
CDS	132..605
Translation	MTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP

Target ORF information:

RefSeq Version	NM_001199853.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 3 (AK3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199853.1

ORF Insert Sequence:

ATGACTCGGC TGGCCCTTCA TGAGCTGAAA AATCTCACCC AGTATAGCTG GCTGTTGGAT 
GGTTTTCCAA GGACACTTCC ACAGGCAGAA GCCCTAGATA GAGCTTATCA GATCGACACA 
GTGATTAACC TGAATGTGCC CTTTGAGGTC ATTAAACAAC GCCTTACTGC TCGCTGGATT 
CATCCCGCCA GTGGCCGAGT CTATAACATT GAATTCAACC CTCCCAAAAC TGTGGGCATT 
GATGACCTGA CTGGGGAGCC TCTCATTCAG CGTGAGGATG ATAAACCAGA GACGGTTATC 
AAGAGACTAA AGGCTTATGA AGACCAAACA AAGCCAGTCC TGGAATATTA CCAGAAAAAA 
GGGGTGCTGG AAACATTCTC CGGAACAGAA ACCAACAAGA TTTGGCCCTA TGTATATGCT 
TTCCTACAAA CTAAAGTTCC ACAAAGAAGC CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK3 ( NM_016282.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057366.2 Homo sapiens adenylate kinase 3 (AK3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu11261
Clone ID Related Accession (Same CDS sequence)	NM_016282.4 , NM_016282.3
Accession Version	NM_016282.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	GTP:AMP phosphotransferase AK3, mitochondrial isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK001553.1, AL136231.12, AF100785.1 and BX640794.1. On Nov 23, 2018 this sequence version replaced NM_016282.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 4 both encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.217486.1, SRR1660805.175169.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000381809.8/ ENSP00000371230.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGGCGT CCGCGCGGCT GCTGCGAGCG GTGATCATGG GGGCCCCGGG CTCGGGCAAG 
GGCACCGTGT CGTCGCGCAT CACTACACAC TTCGAGCTGA AGCACCTCTC CAGCGGGGAC 
CTGCTCCGGG ACAACATGCT GCGGGGCACA GAAATTGGCG TGTTAGCCAA GGCTTTCATT 
GACCAAGGGA AACTCATCCC AGATGATGTC ATGACTCGGC TGGCCCTTCA TGAGCTGAAA 
AATCTCACCC AGTATAGCTG GCTGTTGGAT GGTTTTCCAA GGACACTTCC ACAGGCAGAA 
GCCCTAGATA GAGCTTATCA GATCGACACA GTGATTAACC TGAATGTGCC CTTTGAGGTC 
ATTAAACAAC GCCTTACTGC TCGCTGGATT CATCCCGCCA GTGGCCGAGT CTATAACATT 
GAATTCAACC CTCCCAAAAC TGTGGGCATT GATGACCTGA CTGGGGAGCC TCTCATTCAG 
CGTGAGGATG ATAAACCAGA GACGGTTATC AAGAGACTAA AGGCTTATGA AGACCAAACA 
AAGCCAGTCC TGGAATATTA CCAGAAAAAA GGGGTGCTGG AAACATTCTC CGGAACAGAA 
ACCAACAAGA TTTGGCCCTA TGTATATGCT TTCCTACAAA CTAAAGTTCC ACAAAGAAGC 
CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057366.2
CDS	116..799
Translation	MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP

Target ORF information:

RefSeq Version	NM_016282.4
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 3 (AK3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016282.4

ORF Insert Sequence:

ATGGGGGCGT CCGCGCGGCT GCTGCGAGCG GTGATCATGG GGGCCCCGGG CTCGGGCAAG 
GGCACCGTGT CGTCGCGCAT CACTACACAC TTCGAGCTGA AGCACCTCTC CAGCGGGGAC 
CTGCTCCGGG ACAACATGCT GCGGGGCACA GAAATTGGCG TGTTAGCCAA GGCTTTCATT 
GACCAAGGGA AACTCATCCC AGATGATGTC ATGACTCGGC TGGCCCTTCA TGAGCTGAAA 
AATCTCACCC AGTATAGCTG GCTGTTGGAT GGTTTTCCAA GGACACTTCC ACAGGCAGAA 
GCCCTAGATA GAGCTTATCA GATCGACACA GTGATTAACC TGAATGTGCC CTTTGAGGTC 
ATTAAACAAC GCCTTACTGC TCGCTGGATT CATCCCGCCA GTGGCCGAGT CTATAACATT 
GAATTCAACC CTCCCAAAAC TGTGGGCATT GATGACCTGA CTGGGGAGCC TCTCATTCAG 
CGTGAGGATG ATAAACCAGA GACGGTTATC AAGAGACTAA AGGCTTATGA AGACCAAACA 
AAGCCAGTCC TGGAATATTA CCAGAAAAAA GGGGTGCTGG AAACATTCTC CGGAACAGAA 
ACCAACAAGA TTTGGCCCTA TGTATATGCT TTCCTACAAA CTAAAGTTCC ACAAAGAAGC 
CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK3 ( NM_016282.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057366.2 Homo sapiens adenylate kinase 3 (AK3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu11261
Clone ID Related Accession (Same CDS sequence)	NM_016282.4 , NM_016282.3
Accession Version	NM_016282.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	GTP:AMP phosphotransferase AK3, mitochondrial isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI601245.1, AK001553.1, AL136231.12, AF100785.1 and BX640794.1. On Dec 23, 2010 this sequence version replaced NM_016282.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 4 both encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.279353.1, SRR1660805.175169.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGGCGT CCGCGCGGCT GCTGCGAGCG GTGATCATGG GGGCCCCGGG CTCGGGCAAG 
GGCACCGTGT CGTCGCGCAT CACTACACAC TTCGAGCTGA AGCACCTCTC CAGCGGGGAC 
CTGCTCCGGG ACAACATGCT GCGGGGCACA GAAATTGGCG TGTTAGCCAA GGCTTTCATT 
GACCAAGGGA AACTCATCCC AGATGATGTC ATGACTCGGC TGGCCCTTCA TGAGCTGAAA 
AATCTCACCC AGTATAGCTG GCTGTTGGAT GGTTTTCCAA GGACACTTCC ACAGGCAGAA 
GCCCTAGATA GAGCTTATCA GATCGACACA GTGATTAACC TGAATGTGCC CTTTGAGGTC 
ATTAAACAAC GCCTTACTGC TCGCTGGATT CATCCCGCCA GTGGCCGAGT CTATAACATT 
GAATTCAACC CTCCCAAAAC TGTGGGCATT GATGACCTGA CTGGGGAGCC TCTCATTCAG 
CGTGAGGATG ATAAACCAGA GACGGTTATC AAGAGACTAA AGGCTTATGA AGACCAAACA 
AAGCCAGTCC TGGAATATTA CCAGAAAAAA GGGGTGCTGG AAACATTCTC CGGAACAGAA 
ACCAACAAGA TTTGGCCCTA TGTATATGCT TTCCTACAAA CTAAAGTTCC ACAAAGAAGC 
CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057366.2
CDS	223..906
Translation	MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP

Target ORF information:

RefSeq Version	NM_016282.3
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 3 (AK3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016282.3

ORF Insert Sequence:

ATGGGGGCGT CCGCGCGGCT GCTGCGAGCG GTGATCATGG GGGCCCCGGG CTCGGGCAAG 
GGCACCGTGT CGTCGCGCAT CACTACACAC TTCGAGCTGA AGCACCTCTC CAGCGGGGAC 
CTGCTCCGGG ACAACATGCT GCGGGGCACA GAAATTGGCG TGTTAGCCAA GGCTTTCATT 
GACCAAGGGA AACTCATCCC AGATGATGTC ATGACTCGGC TGGCCCTTCA TGAGCTGAAA 
AATCTCACCC AGTATAGCTG GCTGTTGGAT GGTTTTCCAA GGACACTTCC ACAGGCAGAA 
GCCCTAGATA GAGCTTATCA GATCGACACA GTGATTAACC TGAATGTGCC CTTTGAGGTC 
ATTAAACAAC GCCTTACTGC TCGCTGGATT CATCCCGCCA GTGGCCGAGT CTATAACATT 
GAATTCAACC CTCCCAAAAC TGTGGGCATT GATGACCTGA CTGGGGAGCC TCTCATTCAG 
CGTGAGGATG ATAAACCAGA GACGGTTATC AAGAGACTAA AGGCTTATGA AGACCAAACA 
AAGCCAGTCC TGGAATATTA CCAGAAAAAA GGGGTGCTGG AAACATTCTC CGGAACAGAA 
ACCAACAAGA TTTGGCCCTA TGTATATGCT TTCCTACAAA CTAAAGTTCC ACAAAGAAGC 
CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK3 ( NM_001199852.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186781.1 Homo sapiens adenylate kinase 3 (AK3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10745
Clone ID Related Accession (Same CDS sequence)	NM_001199852.2 , NM_001199852.1
Accession Version	NM_001199852.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 564bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	GTP:AMP phosphotransferase AK3, mitochondrial isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298200.1, AK001553.1, AL136231.12, AF100785.1 and BX640794.1. On May 31, 2019 this sequence version replaced NM_001199852.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.254186.1, SRR1660809.130828.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGGCGT CCGCGCGGCT GCTGCGAGCG GTGATCATGG GGGCCCCGGG CTCGGGCAAG 
GGCACCGTGT CGTCGCGCAT CACTACACAC TTCGAGCTGA AGCACCTCTC CAGCGGGGAC 
CTGCTCCGGG ACAACATGCT GCGGGGCACA GGTTTTCCAA GGACACTTCC ACAGGCAGAA 
GCCCTAGATA GAGCTTATCA GATCGACACA GTGATTAACC TGAATGTGCC CTTTGAGGTC 
ATTAAACAAC GCCTTACTGC TCGCTGGATT CATCCCGCCA GTGGCCGAGT CTATAACATT 
GAATTCAACC CTCCCAAAAC TGTGGGCATT GATGACCTGA CTGGGGAGCC TCTCATTCAG 
CGTGAGGATG ATAAACCAGA GACGGTTATC AAGAGACTAA AGGCTTATGA AGACCAAACA 
AAGCCAGTCC TGGAATATTA CCAGAAAAAA GGGGTGCTGG AAACATTCTC CGGAACAGAA 
ACCAACAAGA TTTGGCCCTA TGTATATGCT TTCCTACAAA CTAAAGTTCC ACAAAGAAGC 
CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186781.1
CDS	116..679
Translation	MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP

Target ORF information:

RefSeq Version	NM_001199852.2
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 3 (AK3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199852.2

ORF Insert Sequence:

ATGGGGGCGT CCGCGCGGCT GCTGCGAGCG GTGATCATGG GGGCCCCGGG CTCGGGCAAG 
GGCACCGTGT CGTCGCGCAT CACTACACAC TTCGAGCTGA AGCACCTCTC CAGCGGGGAC 
CTGCTCCGGG ACAACATGCT GCGGGGCACA GGTTTTCCAA GGACACTTCC ACAGGCAGAA 
GCCCTAGATA GAGCTTATCA GATCGACACA GTGATTAACC TGAATGTGCC CTTTGAGGTC 
ATTAAACAAC GCCTTACTGC TCGCTGGATT CATCCCGCCA GTGGCCGAGT CTATAACATT 
GAATTCAACC CTCCCAAAAC TGTGGGCATT GATGACCTGA CTGGGGAGCC TCTCATTCAG 
CGTGAGGATG ATAAACCAGA GACGGTTATC AAGAGACTAA AGGCTTATGA AGACCAAACA 
AAGCCAGTCC TGGAATATTA CCAGAAAAAA GGGGTGCTGG AAACATTCTC CGGAACAGAA 
ACCAACAAGA TTTGGCCCTA TGTATATGCT TTCCTACAAA CTAAAGTTCC ACAAAGAAGC 
CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK3 ( NM_001199852.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186781.1 Homo sapiens adenylate kinase 3 (AK3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10745
Clone ID Related Accession (Same CDS sequence)	NM_001199852.2 , NM_001199852.1
Accession Version	NM_001199852.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 564bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	GTP:AMP phosphotransferase AK3, mitochondrial isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI601245.1, AK298200.1, AK001553.1, AL136231.12, AF100785.1 and BX640794.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.254186.1, SRR1660803.71774.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGGCGT CCGCGCGGCT GCTGCGAGCG GTGATCATGG GGGCCCCGGG CTCGGGCAAG 
GGCACCGTGT CGTCGCGCAT CACTACACAC TTCGAGCTGA AGCACCTCTC CAGCGGGGAC 
CTGCTCCGGG ACAACATGCT GCGGGGCACA GGTTTTCCAA GGACACTTCC ACAGGCAGAA 
GCCCTAGATA GAGCTTATCA GATCGACACA GTGATTAACC TGAATGTGCC CTTTGAGGTC 
ATTAAACAAC GCCTTACTGC TCGCTGGATT CATCCCGCCA GTGGCCGAGT CTATAACATT 
GAATTCAACC CTCCCAAAAC TGTGGGCATT GATGACCTGA CTGGGGAGCC TCTCATTCAG 
CGTGAGGATG ATAAACCAGA GACGGTTATC AAGAGACTAA AGGCTTATGA AGACCAAACA 
AAGCCAGTCC TGGAATATTA CCAGAAAAAA GGGGTGCTGG AAACATTCTC CGGAACAGAA 
ACCAACAAGA TTTGGCCCTA TGTATATGCT TTCCTACAAA CTAAAGTTCC ACAAAGAAGC 
CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186781.1
CDS	223..786
Translation	MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP

Target ORF information:

RefSeq Version	NM_001199852.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 3 (AK3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199852.1

ORF Insert Sequence:

ATGGGGGCGT CCGCGCGGCT GCTGCGAGCG GTGATCATGG GGGCCCCGGG CTCGGGCAAG 
GGCACCGTGT CGTCGCGCAT CACTACACAC TTCGAGCTGA AGCACCTCTC CAGCGGGGAC 
CTGCTCCGGG ACAACATGCT GCGGGGCACA GGTTTTCCAA GGACACTTCC ACAGGCAGAA 
GCCCTAGATA GAGCTTATCA GATCGACACA GTGATTAACC TGAATGTGCC CTTTGAGGTC 
ATTAAACAAC GCCTTACTGC TCGCTGGATT CATCCCGCCA GTGGCCGAGT CTATAACATT 
GAATTCAACC CTCCCAAAAC TGTGGGCATT GATGACCTGA CTGGGGAGCC TCTCATTCAG 
CGTGAGGATG ATAAACCAGA GACGGTTATC AAGAGACTAA AGGCTTATGA AGACCAAACA 
AAGCCAGTCC TGGAATATTA CCAGAAAAAA GGGGTGCTGG AAACATTCTC CGGAACAGAA 
ACCAACAAGA TTTGGCCCTA TGTATATGCT TTCCTACAAA CTAAAGTTCC ACAAAGAAGC 
CAGAAAGCTT CAGTTACTCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Candidate predisposing germline copy number variants in early onset colorectal cancer patients.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico19(5)625-632(2017 May)
Brea-Fernandez AJ,Fernandez-Rozadilla C,Alvarez-Barona M,Azuara D,Ginesta MM,Clofent J,de Castro L,Gonzalez D,Andreu M,Bessa X,Llor X,Xicola R,Jover R,Castells A,Castellvi-Bel S,Capella G,Carracedo A,Ruiz-Ponte C

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
PLoS genetics8(3)e1002559(2012)
Kenny EE,Pe'er I,Karban A,Ozelius L,Mitchell AA,Ng SM,Erazo M,Ostrer H,Abraham C,Abreu MT,Atzmon G,Barzilai N,Brant SR,Bressman S,Burns ER,Chowers Y,Clark LN,Darvasi A,Doheny D,Duerr RH,Eliakim R,Giladi N,Gregersen PK,Hakonarson H,Jones MR,Marder K,McGovern DP,Mulle J,Orr-Urtreger A,Proctor DD,Pulver A,Rotter JI,Silverberg MS,Ullman T,Warren ST,Waterman M,Zhang W,Bergman A,Mayer L,Katz S,Desnick RJ,Cho JH,Peter I

New gene functions in megakaryopoiesis and platelet formation.
Nature480(7376)201-8(2011 Nov)
Gieger C,Radhakrishnan A,Cvejic A,Tang W,Porcu E,Pistis G,Serbanovic-Canic J,Elling U,Goodall AH,Labrune Y,Lopez LM,M?gi R,Meacham S,Okada Y,Pirastu N,Sorice R,Teumer A,Voss K,Zhang W,Ramirez-Solis R,Bis JC,Ellinghaus D,G?gele M,Hottenga JJ,Langenberg C,Kovacs P,O'Reilly PF,Shin SY,Esko T,Hartiala J,Kanoni S,Murgia F,Parsa A,Stephens J,van der Harst P,Ellen van der Schoot C,Allayee H,Attwood A,Balkau B,Bastardot F,Basu S,Baumeister SE,Biino G,Bomba L,Bonnefond A,Cambien F,Chambers JC,Cucca F,D'Adamo P,Davies G,de Boer RA,de Geus EJ,D?ring A,Elliott P,Erdmann J,Evans DM,Falchi M,Feng W,Folsom AR,Frazer IH,Gibson QD,Glazer NL,Hammond C,Hartikainen AL,Heckbert SR,Hengstenberg C,Hersch M,Illig T,Loos RJ,Jolley J,Khaw KT,K?hnel B,Kyrtsonis MC,Lagou V,Lloyd-Jones H,Lumley T,Mangino M,Maschio A,Mateo Leach I,McKnight B,Memari Y,Mitchell BD,Montgomery GW,Nakamura Y,Nauck M,Navis G,N?thlings U,Nolte IM,Porteous DJ,Pouta A,Pramstaller PP,Pullat J,Ring SM,Rotter JI,Ruggiero D,Ruokonen A,Sala C,Samani NJ,Sambrook J,Schlessinger D,Schreiber S,Schunkert H,Scott J,Smith NL,Snieder H,Starr JM,Stumvoll M,Takahashi A,Tang WH,Taylor K,Tenesa A,Lay Thein S,T?njes A,Uda M,Ulivi S,van Veldhuisen DJ,Visscher PM,V?lker U,Wichmann HE,Wiggins KL,Willemsen G,Yang TP,Hua Zhao J,Zitting P,Bradley JR,Dedoussis GV,Gasparini P,Hazen SL,Metspalu A,Pirastu M,Shuldiner AR,Joost van Pelt L,Zwaginga JJ,Boomsma DI,Deary IJ,Franke A,Froguel P,Ganesh SK,Jarvelin MR,Martin NG,Meisinger C,Psaty BM,Spector TD,Wareham NJ,Akkerman JW,Ciullo M,Deloukas P,Greinacher A,Jupe S,Kamatani N,Khadake J,Kooner JS,Penninger J,Prokopenko I,Stemple D,Toniolo D,Wernisch L,Sanna S,Hicks AA,Rendon A,Ferreira MA,Ouwehand WH,Soranzo N

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ

Genome-wide association study of hematological and biochemical traits in a Japanese population.
Nature genetics42(3)210-5(2010 Mar)
Kamatani Y,Matsuda K,Okada Y,Kubo M,Hosono N,Daigo Y,Nakamura Y,Kamatani N

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AK3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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