TRIM6-TRIM34 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TRIM6-TRIM34
Entrez Gene ID	445372
Full Name	TRIM6-TRIM34 readthrough
Synonyms	IFP1,RNF21,TRIM34
General protein information	Preferred Names TRIM6-TRIM34 readthrough Names tripartite motif-containing 6 and tripartite motif-containing 34 interferon-responsive finger protein 1 long form
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.4
Summary	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene represents a readthrough transcript from genes TRIM6 and TRIM34, and it was described as a splice variant of TRIM34. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. [provided by RefSeq, Nov 2009].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003819.3	NP_001003819.1	tripartite motif-containing 6 and tripartite motif-containing 34
NM_001003819.4	NP_001003819.1	tripartite motif-containing 6 and tripartite motif-containing 34

Pathways from BioSystems

Homologies

Homo sapiens (human)	TRIM6-TRIM34	NP_001003819.1
Canis lupus familiaris (dog)	TRIM34	NP_001192120.1
Bos taurus (cattle)	TRIM34	NP_001039926.1
	LOC714619	XP_001104479.1
Mus musculus (house mouse)	Trim34a	NP_109609.2
Mus musculus (house mouse)	Trim34b	NP_001230845.1
Rattus norvegicus (Norway rat)	Trim34	NP_001263420.1

Gene Ontology
Bibliography

Related articles in PubMed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Lauc G, Huffman JE, Pu?i? M, Zgaga L, Adamczyk B, Mu?ini? A, Novokmet M, Pola?ek O, Gornik O, Kri?ti? J, Keser T, Vitart V, Scheijen B, Uh HW, Molokhia M, Patrick AL, McKeigue P, Kol?i? I, Luki? IK, Swann O, van Leeuwen FN, Ruhaak LR, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, de Craen AJ, Deelder AM, Zeng Q, Wang W, Hastie ND, Gyllensten U, Wilson JF, Wuhrer M, Wright AF, Rudd PM, Hayward C, Aulchenko Y, Campbell H, Rudan I
PLoS genetics9(1)e1003225(2013)

Expression of conjoined genes: another mechanism for gene regulation in eukaryotes.
Prakash T, Sharma VK, Adati N, Ozawa R, Kumar N, Nishida Y, Fujikake T, Takeda T, Taylor TD
PloS one5(10)e13284(2010 Oct)

Functional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domains.
Li X, Li Y, Stremlau M, Yuan W, Song B, Perron M, Sodroski J
Journal of virology80(13)6198-206(2006 Jul)

Molecular cloning of ring finger protein 21 (RNF21)/interferon-responsive finger protein (ifp1), which possesses two RING-B box-coiled coil domains in tandem.
Orimo A, Tominaga N, Yoshimura K, Yamauchi Y, Nomura M, Sato M, Nogi Y, Suzuki M, Suzuki H, Ikeda K, Inoue S, Muramatsu M
Genomics69(1)143-9(2000 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

heterologous RING, B-box 2, and CC domains from related TRIM proteins can functionally substitute for TRIM5alpha(rh) domains.
Title: Functional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domains.

The following TRIM6-TRIM34 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRIM6-TRIM34 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09265	NM_001003819.4 Latest version!	Homo sapiens TRIM6-TRIM34 readthrough (TRIM6-TRIM34), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$265.30 $379.00
View Old Accession Versions >>
OHu09265	NM_001003819.3	Homo sapiens TRIM6-TRIM34 readthrough (TRIM6-TRIM34), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TRIM6-TRIM34 ( NM_001003819.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001003819.1 Homo sapiens TRIM6-TRIM34 readthrough (TRIM6-TRIM34), mRNA.

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CloneID	OHu09265
Clone ID Related Accession (Same CDS sequence)	NM_001003819.3 , NM_001003819.4
Accession Version	NM_001003819.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2529bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-15
Organism	Homo sapiens(human)
Product	tripartite motif-containing 6 and tripartite motif-containing 34
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC015691.6, BC140722.1 and AB039903.1. On Oct 30, 2010 this sequence version replaced NM_001003819.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AB039903.1, BC136871.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## readthrough transcript :: includes exons from GeneID 53840, 117854 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTGCGGGT CAGAGAGGAT TCTACAGGCA GGAAACATCT TAGAAATCAG GGTTGGGCAG 
GCAGGAGCCA GGAGAGTAGC TACAATGACT TCACCAGTAC TGGTGGACAT ACGAGAAGAG 
GTGACCTGCC CTATCTGCCT GGAGCTCCTA ACAGAACCCC TGAGCATAGA CTGTGGCCAC 
AGCTTCTGCC AAGCCTGCAT CACACCAAAT GGCAGGGAAT CAGTGATTGG TCAAGAAGGG 
GAAAGAAGCT GCCCTGTGTG CCAGACCAGC TACCAGCCAG GGAACCTGCG GCCTAATCGG 
CATCTGGCCA ACATAGTGAG GCGGCTCAGA GAGGTAGTGT TGGGCCCTGG GAAGCAGCTG 
AAAGCAGTTC TTTGTGCAGA CCATGGAGAA AAACTGCAGC TCTTCTGTCA GGAGGATGGG 
AAGGTCATTT GCTGGCTTTG TGAGCGGTCT CAGGAGCACC GTGGTCACCA CACGTTCCTC 
GTGGAGGAGG TTGCCCAGGA GTACCAGGAG AAGTTTCAGG AGTCTCTAAA GAAGCTGAAG 
AACGAGGAGC AGGAAGCTGA GAAGCTAACA GCTTTTATCA GAGAGAAGAA AACATCCTGG 
AAGAATCAGA TGGAGCCTGA GAGATGCAGG ATCCAGACAG AGTTTAATCA GCTGCGAAAT 
ATCCTAGACA GAGTGGAGCA ACGGGAGCTG AAAAAGCTGG AACAGGAAGA GAAGAAGGGG 
CTACGAATTA TAGAAGAGGC TGAGAATGAT CTGGTCCACC AGACCCAGTC GCTGCGAGAG 
CTCATCTCGG ATCTGGAGCG TCGATGTCAG GGGTCAACAA TGGAGCTGCT GCAGGATGTG 
AGTGATGTCA CAGAAAGGAG TGAGTTCTGG ACCCTGAGGA AGCCAGAAGC TCTCCCTACA 
AAGCTGAGAA GTATGTTCCG AGCCCCAGAT CTGAAAAGGA TGCTGCGAGT GTGTAGAGAG 
CTGACAGATG TCCAAAGCTA CTGGGCCATC CAGGGGTCTT TAACCAGAAG AGAGAGGAGA 
GCCTCAGGAG TTAGGACCAG AAGAAGCCAG GGAAGCAGTG CAATGGCTTC AAAAATCTTG 
CTTAACGTAC AAGAGGAGGT GACCTGTCCC ATCTGCCTGG AGCTGTTGAC AGAACCCTTG 
AGTCTAGACT GTGGCCACAG CCTCTGCCGA GCCTGCATCA CTGTGAGCAA CAAGGAGGCA 
GTGACCAGCA TGGGAGGAAA AAGCAGCTGT CCTGTGTGTG GTATCAGTTA CTCATTTGAA 
CATCTACAGG CTAATCAGCA TCTGGCCAAC ATAGTGGAGA GACTCAAGGA GGTCAAGTTG 
AGCCCAGACA ATGGGAAGAA GAGAGATCTC TGTGATCATC ATGGAGAGAA ACTCCTACTC 
TTCTGTAAGG AGGATAGGAA AGTCATTTGC TGGCTTTGTG AGCGGTCTCA GGAGCACCGT 
GGTCACCACA CAGTCCTCAC GGAGGAAGTA TTCAAGGAAT GTCAGGAGAA ACTCCAGGCA 
GTCCTCAAGA GGCTGAAGAA GGAAGAGGAG GAAGCTGAGA AGCTGGAAGC TGACATCAGA 
GAAGAGAAAA CTTCCTGGAA GTATCAGGTA CAAACTGAGA GACAAAGGAT ACAAACAGAA 
TTTGATCAGC TTAGAAGCAT CCTAAATAAT GAGGAGCAGA GAGAGCTGCA AAGATTGGAA 
GAAGAAGAAA AGAAGACGCT GGATAAGTTT GCAGAGGCTG AGGATGAGCT AGTTCAGCAG 
AAGCAGTTGG TGAGAGAGCT CATCTCAGAT GTGGAGTGTC GGAGTCAGTG GTCAACAATG 
GAGCTGCTGC AGGACATGAG TGGAATCATG AAATGGAGTG AGATCTGGAG GCTGAAAAAG 
CCAAAAATGG TTTCCAAGAA ACTGAAGACT GTATTCCATG CTCCAGATCT GAGTAGGATG 
CTGCAAATGT TTAGAGAACT GACAGCTGTC CGGTGCTACT GGGTGGATGT CACACTGAAT 
TCAGTCAACC TAAATTTGAA TCTTGTCCTT TCAGAAGATC AGAGACAAGT GATATCTGTG 
CCAATTTGGC CTTTTCAGTG TTATAATTAT GGTGTCTTGG GATCCCAATA TTTCTCCTCT 
GGGAAACATT ACTGGGAAGT GGACGTGTCC AAGAAAACTG CCTGGATCCT GGGGGTATAC 
TGTAGAACAT ATTCCCGCCA TATGAAGTAT GTTGTTAGAA GATGTGCAAA TCGTCAAAAT 
CTTTACACCA AATACAGACC TCTATTTGGC TACTGGGTTA TAGGGTTACA GAATAAATGT 
AAGTATGGTG TCTTTGAAGA GTCTTTGTCC TCTGATCCCG AGGTTTTGAC TCTCTCCATG 
GCTGTGCCTC CCTGCCGTGT TGGGGTTTTC CTCGACTATG AAGCAGGCAT TGTCTCATTT 
TTCAATGTCA CAAGCCATGG CTCCCTCATT TACAAGTTCT CTAAATGTTG CTTTTCTCAG 
CCTGTTTATC CATATTTCAA TCCTTGGAAC TGTCCAGCTC CCATGACTCT ATGCCCACCA 
AGCTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003819.1
CDS	264..2792
Translation	MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWAIQGSLTRRERRASGVRTRRSQGSSAMASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPPSS

Target ORF information:

RefSeq Version	NM_001003819.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TRIM6-TRIM34 readthrough (TRIM6-TRIM34), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003819.3

ORF Insert Sequence:

ATGTGCGGGT CAGAGAGGAT TCTACAGGCA GGAAACATCT TAGAAATCAG GGTTGGGCAG 
GCAGGAGCCA GGAGAGTAGC TACAATGACT TCACCAGTAC TGGTGGACAT ACGAGAAGAG 
GTGACCTGCC CTATCTGCCT GGAGCTCCTA ACAGAACCCC TGAGCATAGA CTGTGGCCAC 
AGCTTCTGCC AAGCCTGCAT CACACCAAAT GGCAGGGAAT CAGTGATTGG TCAAGAAGGG 
GAAAGAAGCT GCCCTGTGTG CCAGACCAGC TACCAGCCAG GGAACCTGCG GCCTAATCGG 
CATCTGGCCA ACATAGTGAG GCGGCTCAGA GAGGTAGTGT TGGGCCCTGG GAAGCAGCTG 
AAAGCAGTTC TTTGTGCAGA CCATGGAGAA AAACTGCAGC TCTTCTGTCA GGAGGATGGG 
AAGGTCATTT GCTGGCTTTG TGAGCGGTCT CAGGAGCACC GTGGTCACCA CACGTTCCTC 
GTGGAGGAGG TTGCCCAGGA GTACCAGGAG AAGTTTCAGG AGTCTCTAAA GAAGCTGAAG 
AACGAGGAGC AGGAAGCTGA GAAGCTAACA GCTTTTATCA GAGAGAAGAA AACATCCTGG 
AAGAATCAGA TGGAGCCTGA GAGATGCAGG ATCCAGACAG AGTTTAATCA GCTGCGAAAT 
ATCCTAGACA GAGTGGAGCA ACGGGAGCTG AAAAAGCTGG AACAGGAAGA GAAGAAGGGG 
CTACGAATTA TAGAAGAGGC TGAGAATGAT CTGGTCCACC AGACCCAGTC GCTGCGAGAG 
CTCATCTCGG ATCTGGAGCG TCGATGTCAG GGGTCAACAA TGGAGCTGCT GCAGGATGTG 
AGTGATGTCA CAGAAAGGAG TGAGTTCTGG ACCCTGAGGA AGCCAGAAGC TCTCCCTACA 
AAGCTGAGAA GTATGTTCCG AGCCCCAGAT CTGAAAAGGA TGCTGCGAGT GTGTAGAGAG 
CTGACAGATG TCCAAAGCTA CTGGGCCATC CAGGGGTCTT TAACCAGAAG AGAGAGGAGA 
GCCTCAGGAG TTAGGACCAG AAGAAGCCAG GGAAGCAGTG CAATGGCTTC AAAAATCTTG 
CTTAACGTAC AAGAGGAGGT GACCTGTCCC ATCTGCCTGG AGCTGTTGAC AGAACCCTTG 
AGTCTAGACT GTGGCCACAG CCTCTGCCGA GCCTGCATCA CTGTGAGCAA CAAGGAGGCA 
GTGACCAGCA TGGGAGGAAA AAGCAGCTGT CCTGTGTGTG GTATCAGTTA CTCATTTGAA 
CATCTACAGG CTAATCAGCA TCTGGCCAAC ATAGTGGAGA GACTCAAGGA GGTCAAGTTG 
AGCCCAGACA ATGGGAAGAA GAGAGATCTC TGTGATCATC ATGGAGAGAA ACTCCTACTC 
TTCTGTAAGG AGGATAGGAA AGTCATTTGC TGGCTTTGTG AGCGGTCTCA GGAGCACCGT 
GGTCACCACA CAGTCCTCAC GGAGGAAGTA TTCAAGGAAT GTCAGGAGAA ACTCCAGGCA 
GTCCTCAAGA GGCTGAAGAA GGAAGAGGAG GAAGCTGAGA AGCTGGAAGC TGACATCAGA 
GAAGAGAAAA CTTCCTGGAA GTATCAGGTA CAAACTGAGA GACAAAGGAT ACAAACAGAA 
TTTGATCAGC TTAGAAGCAT CCTAAATAAT GAGGAGCAGA GAGAGCTGCA AAGATTGGAA 
GAAGAAGAAA AGAAGACGCT GGATAAGTTT GCAGAGGCTG AGGATGAGCT AGTTCAGCAG 
AAGCAGTTGG TGAGAGAGCT CATCTCAGAT GTGGAGTGTC GGAGTCAGTG GTCAACAATG 
GAGCTGCTGC AGGACATGAG TGGAATCATG AAATGGAGTG AGATCTGGAG GCTGAAAAAG 
CCAAAAATGG TTTCCAAGAA ACTGAAGACT GTATTCCATG CTCCAGATCT GAGTAGGATG 
CTGCAAATGT TTAGAGAACT GACAGCTGTC CGGTGCTACT GGGTGGATGT CACACTGAAT 
TCAGTCAACC TAAATTTGAA TCTTGTCCTT TCAGAAGATC AGAGACAAGT GATATCTGTG 
CCAATTTGGC CTTTTCAGTG TTATAATTAT GGTGTCTTGG GATCCCAATA TTTCTCCTCT 
GGGAAACATT ACTGGGAAGT GGACGTGTCC AAGAAAACTG CCTGGATCCT GGGGGTATAC 
TGTAGAACAT ATTCCCGCCA TATGAAGTAT GTTGTTAGAA GATGTGCAAA TCGTCAAAAT 
CTTTACACCA AATACAGACC TCTATTTGGC TACTGGGTTA TAGGGTTACA GAATAAATGT 
AAGTATGGTG TCTTTGAAGA GTCTTTGTCC TCTGATCCCG AGGTTTTGAC TCTCTCCATG 
GCTGTGCCTC CCTGCCGTGT TGGGGTTTTC CTCGACTATG AAGCAGGCAT TGTCTCATTT 
TTCAATGTCA CAAGCCATGG CTCCCTCATT TACAAGTTCT CTAAATGTTG CTTTTCTCAG 
CCTGTTTATC CATATTTCAA TCCTTGGAAC TGTCCAGCTC CCATGACTCT ATGCCCACCA 
AGCTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIM6-TRIM34 ( NM_001003819.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001003819.1 Homo sapiens TRIM6-TRIM34 readthrough (TRIM6-TRIM34), mRNA.

Price & Availability↑

CloneID	OHu09265
Clone ID Related Accession (Same CDS sequence)	NM_001003819.3 , NM_001003819.4
Accession Version	NM_001003819.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2529bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-19
Organism	Homo sapiens(human)
Product	tripartite motif-containing 6 and tripartite motif-containing 34
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC015691.6, BC140722.1 and AB039903.1. On Jun 2, 2019 this sequence version replaced NM_001003819.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AB039903.1, BC140722.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## readthrough transcript :: includes exons from GeneID 53840, 117854 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTGCGGGT CAGAGAGGAT TCTACAGGCA GGAAACATCT TAGAAATCAG GGTTGGGCAG 
GCAGGAGCCA GGAGAGTAGC TACAATGACT TCACCAGTAC TGGTGGACAT ACGAGAAGAG 
GTGACCTGCC CTATCTGCCT GGAGCTCCTA ACAGAACCCC TGAGCATAGA CTGTGGCCAC 
AGCTTCTGCC AAGCCTGCAT CACACCAAAT GGCAGGGAAT CAGTGATTGG TCAAGAAGGG 
GAAAGAAGCT GCCCTGTGTG CCAGACCAGC TACCAGCCAG GGAACCTGCG GCCTAATCGG 
CATCTGGCCA ACATAGTGAG GCGGCTCAGA GAGGTAGTGT TGGGCCCTGG GAAGCAGCTG 
AAAGCAGTTC TTTGTGCAGA CCATGGAGAA AAACTGCAGC TCTTCTGTCA GGAGGATGGG 
AAGGTCATTT GCTGGCTTTG TGAGCGGTCT CAGGAGCACC GTGGTCACCA CACGTTCCTC 
GTGGAGGAGG TTGCCCAGGA GTACCAGGAG AAGTTTCAGG AGTCTCTAAA GAAGCTGAAG 
AACGAGGAGC AGGAAGCTGA GAAGCTAACA GCTTTTATCA GAGAGAAGAA AACATCCTGG 
AAGAATCAGA TGGAGCCTGA GAGATGCAGG ATCCAGACAG AGTTTAATCA GCTGCGAAAT 
ATCCTAGACA GAGTGGAGCA ACGGGAGCTG AAAAAGCTGG AACAGGAAGA GAAGAAGGGG 
CTACGAATTA TAGAAGAGGC TGAGAATGAT CTGGTCCACC AGACCCAGTC GCTGCGAGAG 
CTCATCTCGG ATCTGGAGCG TCGATGTCAG GGGTCAACAA TGGAGCTGCT GCAGGATGTG 
AGTGATGTCA CAGAAAGGAG TGAGTTCTGG ACCCTGAGGA AGCCAGAAGC TCTCCCTACA 
AAGCTGAGAA GTATGTTCCG AGCCCCAGAT CTGAAAAGGA TGCTGCGAGT GTGTAGAGAG 
CTGACAGATG TCCAAAGCTA CTGGGCCATC CAGGGGTCTT TAACCAGAAG AGAGAGGAGA 
GCCTCAGGAG TTAGGACCAG AAGAAGCCAG GGAAGCAGTG CAATGGCTTC AAAAATCTTG 
CTTAACGTAC AAGAGGAGGT GACCTGTCCC ATCTGCCTGG AGCTGTTGAC AGAACCCTTG 
AGTCTAGACT GTGGCCACAG CCTCTGCCGA GCCTGCATCA CTGTGAGCAA CAAGGAGGCA 
GTGACCAGCA TGGGAGGAAA AAGCAGCTGT CCTGTGTGTG GTATCAGTTA CTCATTTGAA 
CATCTACAGG CTAATCAGCA TCTGGCCAAC ATAGTGGAGA GACTCAAGGA GGTCAAGTTG 
AGCCCAGACA ATGGGAAGAA GAGAGATCTC TGTGATCATC ATGGAGAGAA ACTCCTACTC 
TTCTGTAAGG AGGATAGGAA AGTCATTTGC TGGCTTTGTG AGCGGTCTCA GGAGCACCGT 
GGTCACCACA CAGTCCTCAC GGAGGAAGTA TTCAAGGAAT GTCAGGAGAA ACTCCAGGCA 
GTCCTCAAGA GGCTGAAGAA GGAAGAGGAG GAAGCTGAGA AGCTGGAAGC TGACATCAGA 
GAAGAGAAAA CTTCCTGGAA GTATCAGGTA CAAACTGAGA GACAAAGGAT ACAAACAGAA 
TTTGATCAGC TTAGAAGCAT CCTAAATAAT GAGGAGCAGA GAGAGCTGCA AAGATTGGAA 
GAAGAAGAAA AGAAGACGCT GGATAAGTTT GCAGAGGCTG AGGATGAGCT AGTTCAGCAG 
AAGCAGTTGG TGAGAGAGCT CATCTCAGAT GTGGAGTGTC GGAGTCAGTG GTCAACAATG 
GAGCTGCTGC AGGACATGAG TGGAATCATG AAATGGAGTG AGATCTGGAG GCTGAAAAAG 
CCAAAAATGG TTTCCAAGAA ACTGAAGACT GTATTCCATG CTCCAGATCT GAGTAGGATG 
CTGCAAATGT TTAGAGAACT GACAGCTGTC CGGTGCTACT GGGTGGATGT CACACTGAAT 
TCAGTCAACC TAAATTTGAA TCTTGTCCTT TCAGAAGATC AGAGACAAGT GATATCTGTG 
CCAATTTGGC CTTTTCAGTG TTATAATTAT GGTGTCTTGG GATCCCAATA TTTCTCCTCT 
GGGAAACATT ACTGGGAAGT GGACGTGTCC AAGAAAACTG CCTGGATCCT GGGGGTATAC 
TGTAGAACAT ATTCCCGCCA TATGAAGTAT GTTGTTAGAA GATGTGCAAA TCGTCAAAAT 
CTTTACACCA AATACAGACC TCTATTTGGC TACTGGGTTA TAGGGTTACA GAATAAATGT 
AAGTATGGTG TCTTTGAAGA GTCTTTGTCC TCTGATCCCG AGGTTTTGAC TCTCTCCATG 
GCTGTGCCTC CCTGCCGTGT TGGGGTTTTC CTCGACTATG AAGCAGGCAT TGTCTCATTT 
TTCAATGTCA CAAGCCATGG CTCCCTCATT TACAAGTTCT CTAAATGTTG CTTTTCTCAG 
CCTGTTTATC CATATTTCAA TCCTTGGAAC TGTCCAGCTC CCATGACTCT ATGCCCACCA 
AGCTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003819.1
CDS	262..2790
Translation	MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWAIQGSLTRRERRASGVRTRRSQGSSAMASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPPSS

Target ORF information:

RefSeq Version	NM_001003819.4
Organism	Homo sapiens(human)
Definition	Homo sapiens TRIM6-TRIM34 readthrough (TRIM6-TRIM34), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003819.4

ORF Insert Sequence:

ATGTGCGGGT CAGAGAGGAT TCTACAGGCA GGAAACATCT TAGAAATCAG GGTTGGGCAG 
GCAGGAGCCA GGAGAGTAGC TACAATGACT TCACCAGTAC TGGTGGACAT ACGAGAAGAG 
GTGACCTGCC CTATCTGCCT GGAGCTCCTA ACAGAACCCC TGAGCATAGA CTGTGGCCAC 
AGCTTCTGCC AAGCCTGCAT CACACCAAAT GGCAGGGAAT CAGTGATTGG TCAAGAAGGG 
GAAAGAAGCT GCCCTGTGTG CCAGACCAGC TACCAGCCAG GGAACCTGCG GCCTAATCGG 
CATCTGGCCA ACATAGTGAG GCGGCTCAGA GAGGTAGTGT TGGGCCCTGG GAAGCAGCTG 
AAAGCAGTTC TTTGTGCAGA CCATGGAGAA AAACTGCAGC TCTTCTGTCA GGAGGATGGG 
AAGGTCATTT GCTGGCTTTG TGAGCGGTCT CAGGAGCACC GTGGTCACCA CACGTTCCTC 
GTGGAGGAGG TTGCCCAGGA GTACCAGGAG AAGTTTCAGG AGTCTCTAAA GAAGCTGAAG 
AACGAGGAGC AGGAAGCTGA GAAGCTAACA GCTTTTATCA GAGAGAAGAA AACATCCTGG 
AAGAATCAGA TGGAGCCTGA GAGATGCAGG ATCCAGACAG AGTTTAATCA GCTGCGAAAT 
ATCCTAGACA GAGTGGAGCA ACGGGAGCTG AAAAAGCTGG AACAGGAAGA GAAGAAGGGG 
CTACGAATTA TAGAAGAGGC TGAGAATGAT CTGGTCCACC AGACCCAGTC GCTGCGAGAG 
CTCATCTCGG ATCTGGAGCG TCGATGTCAG GGGTCAACAA TGGAGCTGCT GCAGGATGTG 
AGTGATGTCA CAGAAAGGAG TGAGTTCTGG ACCCTGAGGA AGCCAGAAGC TCTCCCTACA 
AAGCTGAGAA GTATGTTCCG AGCCCCAGAT CTGAAAAGGA TGCTGCGAGT GTGTAGAGAG 
CTGACAGATG TCCAAAGCTA CTGGGCCATC CAGGGGTCTT TAACCAGAAG AGAGAGGAGA 
GCCTCAGGAG TTAGGACCAG AAGAAGCCAG GGAAGCAGTG CAATGGCTTC AAAAATCTTG 
CTTAACGTAC AAGAGGAGGT GACCTGTCCC ATCTGCCTGG AGCTGTTGAC AGAACCCTTG 
AGTCTAGACT GTGGCCACAG CCTCTGCCGA GCCTGCATCA CTGTGAGCAA CAAGGAGGCA 
GTGACCAGCA TGGGAGGAAA AAGCAGCTGT CCTGTGTGTG GTATCAGTTA CTCATTTGAA 
CATCTACAGG CTAATCAGCA TCTGGCCAAC ATAGTGGAGA GACTCAAGGA GGTCAAGTTG 
AGCCCAGACA ATGGGAAGAA GAGAGATCTC TGTGATCATC ATGGAGAGAA ACTCCTACTC 
TTCTGTAAGG AGGATAGGAA AGTCATTTGC TGGCTTTGTG AGCGGTCTCA GGAGCACCGT 
GGTCACCACA CAGTCCTCAC GGAGGAAGTA TTCAAGGAAT GTCAGGAGAA ACTCCAGGCA 
GTCCTCAAGA GGCTGAAGAA GGAAGAGGAG GAAGCTGAGA AGCTGGAAGC TGACATCAGA 
GAAGAGAAAA CTTCCTGGAA GTATCAGGTA CAAACTGAGA GACAAAGGAT ACAAACAGAA 
TTTGATCAGC TTAGAAGCAT CCTAAATAAT GAGGAGCAGA GAGAGCTGCA AAGATTGGAA 
GAAGAAGAAA AGAAGACGCT GGATAAGTTT GCAGAGGCTG AGGATGAGCT AGTTCAGCAG 
AAGCAGTTGG TGAGAGAGCT CATCTCAGAT GTGGAGTGTC GGAGTCAGTG GTCAACAATG 
GAGCTGCTGC AGGACATGAG TGGAATCATG AAATGGAGTG AGATCTGGAG GCTGAAAAAG 
CCAAAAATGG TTTCCAAGAA ACTGAAGACT GTATTCCATG CTCCAGATCT GAGTAGGATG 
CTGCAAATGT TTAGAGAACT GACAGCTGTC CGGTGCTACT GGGTGGATGT CACACTGAAT 
TCAGTCAACC TAAATTTGAA TCTTGTCCTT TCAGAAGATC AGAGACAAGT GATATCTGTG 
CCAATTTGGC CTTTTCAGTG TTATAATTAT GGTGTCTTGG GATCCCAATA TTTCTCCTCT 
GGGAAACATT ACTGGGAAGT GGACGTGTCC AAGAAAACTG CCTGGATCCT GGGGGTATAC 
TGTAGAACAT ATTCCCGCCA TATGAAGTAT GTTGTTAGAA GATGTGCAAA TCGTCAAAAT 
CTTTACACCA AATACAGACC TCTATTTGGC TACTGGGTTA TAGGGTTACA GAATAAATGT 
AAGTATGGTG TCTTTGAAGA GTCTTTGTCC TCTGATCCCG AGGTTTTGAC TCTCTCCATG 
GCTGTGCCTC CCTGCCGTGT TGGGGTTTTC CTCGACTATG AAGCAGGCAT TGTCTCATTT 
TTCAATGTCA CAAGCCATGG CTCCCTCATT TACAAGTTCT CTAAATGTTG CTTTTCTCAG 
CCTGTTTATC CATATTTCAA TCCTTGGAAC TGTCCAGCTC CCATGACTCT ATGCCCACCA 
AGCTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
PLoS genetics9(1)e1003225(2013)
Lauc G,Huffman JE,Pu?i? M,Zgaga L,Adamczyk B,Mu?ini? A,Novokmet M,Pola?ek O,Gornik O,Kri?ti? J,Keser T,Vitart V,Scheijen B,Uh HW,Molokhia M,Patrick AL,McKeigue P,Kol?i? I,Luki? IK,Swann O,van Leeuwen FN,Ruhaak LR,Houwing-Duistermaat JJ,Slagboom PE,Beekman M,de Craen AJ,Deelder AM,Zeng Q,Wang W,Hastie ND,Gyllensten U,Wilson JF,Wuhrer M,Wright AF,Rudd PM,Hayward C,Aulchenko Y,Campbell H,Rudan I

Expression of conjoined genes: another mechanism for gene regulation in eukaryotes.
PloS one5(10)e13284(2010 Oct)
Prakash T,Sharma VK,Adati N,Ozawa R,Kumar N,Nishida Y,Fujikake T,Takeda T,Taylor TD

Functional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domains.
Journal of virology80(13)6198-206(2006 Jul)
Li X,Li Y,Stremlau M,Yuan W,Song B,Perron M,Sodroski J

Molecular cloning of ring finger protein 21 (RNF21)/interferon-responsive finger protein (ifp1), which possesses two RING-B box-coiled coil domains in tandem.
Genomics69(1)143-9(2000 Oct)
Orimo A,Tominaga N,Yoshimura K,Yamauchi Y,Nomura M,Sato M,Nogi Y,Suzuki M,Suzuki H,Ikeda K,Inoue S,Muramatsu M