C10orf99 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	C10orf99
Entrez Gene ID	387695
Full Name	chromosome 10 open reading frame 99
Synonyms	AP-57,AP57,CSBF,GPR15L,UNQ1833
General protein information	Preferred Names chromosome 10 open reading frame 99 Names protein GPR15L secreted protein C10orf99 RLLV1833 anti-microbial peptide with 57 amino acid residues antimicrobial peptide-57 colon-derived SUSD2 binding factor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q23.1
Disorder MIM:	617775

mRNA and Protein(s)

mRNA	Protein	Name
NM_207373.3	NP_997256.1	protein GPR15L precursor
NM_207373.2	NP_997256.1	protein GPR15L precursor
XM_005269811.3	XP_005269868.1	protein GPR15L isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	C10orf99	NP_997256.1
Pan troglodytes (chimpanzee)	C10H10orf99	XP_001154133.1

Gene Ontology
Bibliography

Related articles in PubMed

A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia.
Suply T, Hannedouche S, Carte N, Li J, Grosshans B, Schaefer M, Raad L, Beck V, Vidal S, Hiou-Feige A, Beluch N, Barbieri S, Wirsching J, Lageyre N, Hillger F, Debon C, Dawson J, Smith P, Lannoy V, Detheux M, Bitsch F, Falchetto R, Bouwmeester T, Porter J, Baumgarten B, Mansfield K, Carballido JM, Seuwen K, Bassilana F
Science signaling10(496)(2017 Sep)

A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15.
Oc?n B, Pan J, Dinh TT, Chen W, Ballet R, Bscheider M, Habtezion A, Tu H, Zabel BA, Butcher EC
Frontiers in immunology81111(2017)

AP-57/C10orf99 is a new type of multifunctional antimicrobial peptide.
Yang M, Tang M, Ma X, Yang L, He J, Peng X, Guo G, Zhou L, Luo N, Yuan Z, Tong A
Biochemical and biophysical research communications457(3)347-52(2015 Feb)

CSBF/C10orf99, a novel potential cytokine, inhibits colon cancer cell growth through inducing G1 arrest.
Pan W, Cheng Y, Zhang H, Liu B, Mo X, Li T, Li L, Cheng X, Zhang L, Ji J, Wang P, Han W
Scientific reports46812(2014 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Compared with other antimicrobial peptides, AP-57 has its distinct characteristics, including longer sequence length, four cysteines, highly cationic character, cell-specific toxicity, DNA binding and tissue-specific expressing patterns.
Title: AP-57/C10orf99 is a new type of multifunctional antimicrobial peptide.

The following C10orf99 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C10orf99 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30010	NM_207373.3 Latest version!	Homo sapiens chromosome 10 open reading frame 99 (C10orf99), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu44309	XM_005269811.3 Latest version!	Homo sapiens chromosome 10 open reading frame 99 (C10orf99), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu30010	NM_207373.2	Homo sapiens chromosome 10 open reading frame 99 (C10orf99), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

C10orf99 ( NM_207373.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_997256.1 Homo sapiens chromosome 10 open reading frame 99 (C10orf99), mRNA.

Price & Availability↑

CloneID	OHu30010
Clone ID Related Accession (Same CDS sequence)	NM_207373.3 , NM_207373.2
Accession Version	NM_207373.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 246bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Homo sapiens(human)
Product	protein GPR15L precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AW351839.1, AY358751.1 and AI831407.1. On Nov 22, 2018 this sequence version replaced NM_207373.2. ##Evidence-Data-START## Transcript exon combination :: AY358751.1, BE899580.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000372126.4/ ENSP00000361199.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGGCTTC TAGTCCTTTC CAGCCTGCTC TGTATCCTGC TTCTCTGCTT CTCCATCTTC 
TCCACAGAAG GGAAGAGGCG TCCTGCCAAG GCCTGGTCAG GCAGGAGAAC CAGGCTCTGC 
TGCCACCGAG TCCCTAGCCC CAACTCAACA AACCTGAAAG GACATCATGT GAGGCTCTGT 
AAACCATGCA AGCTTGAGCC AGAGCCCCGC CTTTGGGTGG TGCCTGGGGC ACTCCCACAG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997256.1
CDS	52..297
Translation	MRLLVLSSLLCILLLCFSIFSTEGKRRPAKAWSGRRTRLCCHRVPSPNSTNLKGHHVRLCKPCKLEPEPRLWVVPGALPQV

Target ORF information:

RefSeq Version	NM_207373.3
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 10 open reading frame 99 (C10orf99), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207373.3

ORF Insert Sequence:

ATGAGGCTTC TAGTCCTTTC CAGCCTGCTC TGTATCCTGC TTCTCTGCTT CTCCATCTTC 
TCCACAGAAG GGAAGAGGCG TCCTGCCAAG GCCTGGTCAG GCAGGAGAAC CAGGCTCTGC 
TGCCACCGAG TCCCTAGCCC CAACTCAACA AACCTGAAAG GACATCATGT GAGGCTCTGT 
AAACCATGCA AGCTTGAGCC AGAGCCCCGC CTTTGGGTGG TGCCTGGGGC ACTCCCACAG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C10orf99 ( NM_207373.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_997256.1 Homo sapiens chromosome 10 open reading frame 99 (C10orf99), mRNA.

Price & Availability↑

CloneID	OHu30010
Clone ID Related Accession (Same CDS sequence)	NM_207373.3 , NM_207373.2
Accession Version	NM_207373.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 246bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	protein GPR15L precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AW351839.1, AY358751.1 and AI831407.1. On Jan 12, 2007 this sequence version replaced NM_207373.1. ##Evidence-Data-START## Transcript exon combination :: AW351839.1, AY358751.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTTC TAGTCCTTTC CAGCCTGCTC TGTATCCTGC TTCTCTGCTT CTCCATCTTC 
TCCACAGAAG GGAAGAGGCG TCCTGCCAAG GCCTGGTCAG GCAGGAGAAC CAGGCTCTGC 
TGCCACCGAG TCCCTAGCCC CAACTCAACA AACCTGAAAG GACATCATGT GAGGCTCTGT 
AAACCATGCA AGCTTGAGCC AGAGCCCCGC CTTTGGGTGG TGCCTGGGGC ACTCCCACAG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997256.1
CDS	55..300
Translation	MRLLVLSSLLCILLLCFSIFSTEGKRRPAKAWSGRRTRLCCHRVPSPNSTNLKGHHVRLCKPCKLEPEPRLWVVPGALPQV

Target ORF information:

RefSeq Version	NM_207373.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 10 open reading frame 99 (C10orf99), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207373.2

ORF Insert Sequence:

ATGAGGCTTC TAGTCCTTTC CAGCCTGCTC TGTATCCTGC TTCTCTGCTT CTCCATCTTC 
TCCACAGAAG GGAAGAGGCG TCCTGCCAAG GCCTGGTCAG GCAGGAGAAC CAGGCTCTGC 
TGCCACCGAG TCCCTAGCCC CAACTCAACA AACCTGAAAG GACATCATGT GAGGCTCTGT 
AAACCATGCA AGCTTGAGCC AGAGCCCCGC CTTTGGGTGG TGCCTGGGGC ACTCCCACAG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C10orf99 ( XM_005269811.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005269868.1 Homo sapiens chromosome 10 open reading frame 99 (C10orf99), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu44309
Clone ID Related Accession (Same CDS sequence)	XM_005269811.3
Accession Version	XM_005269811.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 399bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein GPR15L isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005269811.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGCTTC TAGTCCTTTC CAGCCTGCTC TGTATCCTGC TTCTCTGCTT CTCCATCTTC 
TCCACAGAAG GGAAGAGGCG TCCTGCCAAG GCCTGGTCAG GCAGGAGAAC CAGGCTCTGC 
TGCCACCGAG TCCCTAGCCC CAACTCAACA AACCTGAAAG CCTTCACAGC AGTGAGCTGC 
AATGTTGGAG GGCTTCATCT CGGGCTGCAA GGACCCTGGG AAAGTTCCAG AACTCCACGT 
CCTTGTCTCA ATTGTGCCAT CAACTTTCAG AGCTATCATG AGCCAACCTC ACCCCACAGG 
GCCTCAGTCG CCACCATGTG GGCCTCTCCA GTGCAAACCA CCGAGCATTC CACCATGACC 
GGTCACAGCT ACAAATCCAG AGACCATCAA TCCTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005269868.1
CDS	89..487
Translation	MRLLVLSSLLCILLLCFSIFSTEGKRRPAKAWSGRRTRLCCHRVPSPNSTNLKAFTAVSCNVGGLHLGLQGPWESSRTPRPCLNCAINFQSYHEPTSPHRASVATMWASPVQTTEHSTMTGHSYKSRDHQSC

Target ORF information:

RefSeq Version	XM_005269811.3
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 10 open reading frame 99 (C10orf99), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005269811.3

ORF Insert Sequence:

ATGAGGCTTC TAGTCCTTTC CAGCCTGCTC TGTATCCTGC TTCTCTGCTT CTCCATCTTC 
TCCACAGAAG GGAAGAGGCG TCCTGCCAAG GCCTGGTCAG GCAGGAGAAC CAGGCTCTGC 
TGCCACCGAG TCCCTAGCCC CAACTCAACA AACCTGAAAG CCTTCACAGC AGTGAGCTGC 
AATGTTGGAG GGCTTCATCT CGGGCTGCAA GGACCCTGGG AAAGTTCCAG AACTCCACGT 
CCTTGTCTCA ATTGTGCCAT CAACTTTCAG AGCTATCATG AGCCAACCTC ACCCCACAGG 
GCCTCAGTCG CCACCATGTG GGCCTCTCCA GTGCAAACCA CCGAGCATTC CACCATGACC 
GGTCACAGCT ACAAATCCAG AGACCATCAA TCCTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia.
Science signaling10(496)(2017 Sep)
Suply T,Hannedouche S,Carte N,Li J,Grosshans B,Schaefer M,Raad L,Beck V,Vidal S,Hiou-Feige A,Beluch N,Barbieri S,Wirsching J,Lageyre N,Hillger F,Debon C,Dawson J,Smith P,Lannoy V,Detheux M,Bitsch F,Falchetto R,Bouwmeester T,Porter J,Baumgarten B,Mansfield K,Carballido JM,Seuwen K,Bassilana F

A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15.
Frontiers in immunology81111(2017)
Oc?n B,Pan J,Dinh TT,Chen W,Ballet R,Bscheider M,Habtezion A,Tu H,Zabel BA,Butcher EC

AP-57/C10orf99 is a new type of multifunctional antimicrobial peptide.
Biochemical and biophysical research communications457(3)347-52(2015 Feb)
Yang M,Tang M,Ma X,Yang L,He J,Peng X,Guo G,Zhou L,Luo N,Yuan Z,Tong A

CSBF/C10orf99, a novel potential cytokine, inhibits colon cancer cell growth through inducing G1 arrest.
Scientific reports46812(2014 Oct)
Pan W,Cheng Y,Zhang H,Liu B,Mo X,Li T,Li L,Cheng X,Zhang L,Ji J,Wang P,Han W

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C10orf99 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム