KRT17 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRT17
Entrez Gene ID	3872
Full Name	keratin 17
Synonyms	39.1,CK-17,K17,PC,PC2,PCHC1
General protein information	Preferred Names keratin 17 Names keratin, type I cytoskeletal 17 cytokeratin-17 keratin 17, type I
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.2
Summary	This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008].
Disorder MIM:	148069
Disorder Html:	Pachyonychia congenita 2, 167210 (3); Steatocystoma multiplex, 184500 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000422.2	NP_000413.1	keratin, type I cytoskeletal 17
NM_000422.3	NP_000413.1	keratin, type I cytoskeletal 17

Pathways from BioSystems

Homologies

	KRT17	XP_002800509.1
Canis lupus familiaris (dog)	KRT17	XP_548100.1
Danio rerio (zebrafish)	si:dkeyp-113d7.4	NP_001107814.1
Danio rerio (zebrafish)	krt1-19d	XP_001342789.4
Xenopus tropicalis (tropical clawed frog)	LOC100490897	XP_002939077.1
Bos taurus (cattle)	KRT17	NP_001098792.1
Danio rerio (zebrafish)	krt15	NP_998688.1
Danio rerio (zebrafish)	krt17	NP_001076574.1
Danio rerio (zebrafish)	zgc:92533	NP_001003445.1
Mus musculus (house mouse)	Krt17	NP_034793.1
Rattus norvegicus (Norway rat)	Krt17	NP_997710.1
Danio rerio (zebrafish)	wu:fb17f05	NP_001186881.1
Danio rerio (zebrafish)	cyt1l	NP_001076351.1
Danio rerio (zebrafish)	cyt1	NP_571182.1
Danio rerio (zebrafish)	zgc:92061	NP_001002383.1
Danio rerio (zebrafish)	zgc:109868	NP_001017824.1
Homo sapiens (human)	KRT17	NP_000413.1
Pan troglodytes (chimpanzee)	KRT17	NP_001138309.1

Gene Ontology

The following KRT17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRT17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23206	NM_000422.3 Latest version!	Homo sapiens keratin 17 (KRT17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu23206	NM_000422.2	Homo sapiens keratin 17 (KRT17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRT17 ( NM_000422.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_000413.1 Homo sapiens keratin 17 (KRT17), mRNA.

Price & Availability↑

CloneID	OHu23206
Clone ID Related Accession (Same CDS sequence)	NM_000422.2 , NM_000422.3
Accession Version	NM_000422.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1299bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-01
Organism	Homo sapiens(human)
Product	keratin, type I cytoskeletal 17
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP226061.1, BC011901.2 and X05803.1. This sequence is a reference standard in the RefSeqGene project. On Aug 29, 2008 this sequence version replaced NM_000422.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK095342.1, BC000159.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGACCACCT CCATCCGCCA GTTCACCTCC TCCAGCTCCA TCAAGGGCTC CTCCGGCCTG 
GGGGGCGGCT CGTCCCGCAC CTCCTGCCGG CTGTCTGGCG GCCTGGGTGC CGGCTCCTGC 
AGGCTGGGAT CTGCTGGCGG CCTGGGCAGC ACCCTCGGGG GTAGCAGCTA CTCCAGCTGC 
TACAGCTTTG GCTCTGGTGG TGGCTATGGC AGCAGCTTTG GGGGTGTTGA TGGGCTGCTG 
GCTGGAGGTG AGAAGGCCAC CATGCAGAAC CTCAATGACC GCCTGGCCTC CTACCTGGAC 
AAGGTGCGTG CCCTGGAGGA GGCCAACACT GAGCTGGAGG TGAAGATCCG TGACTGGTAC 
CAGAGGCAGG CCCCGGGGCC CGCCCGTGAC TACAGCCAGT ACTACAGGAC AATTGAGGAG 
CTGCAGAACA AGATCCTCAC AGCCACCGTG GACAATGCCA ACATCCTGCT ACAGATTGAC 
AATGCCCGTC TGGCTGCTGA TGACTTCCGC ACCAAGTTTG AGACAGAGCA GGCCCTGCGC 
CTGAGTGTGG AGGCCGACAT CAATGGCCTG CGCAGGGTGC TGGATGAGCT GACCCTGGCC 
AGAGCCGACC TGGAGATGCA GATTGAGAAC CTCAAGGAGG AGCTGGCCTA CCTGAAGAAG 
AACCACGAGG AGGAGATGAA CGCCCTGCGA GGCCAGGTGG GTGGTGAGAT CAATGTGGAG 
ATGGACGCTG CCCCAGGCGT GGACCTGAGC CGCATCCTCA ACGAGATGCG TGACCAGTAT 
GAGAAGATGG CAGAGAAGAA CCGCAAGGAT GCCGAGGATT GGTTCTTCAG CAAGACAGAG 
GAACTGAACC GCGAGGTGGC CACCAACAGT GAGCTGGTGC AGAGTGGCAA GAGTGAGATC 
TCGGAGCTCC GGCGCACCAT GCAGGCCTTG GAGATAGAGC TGCAGTCCCA GCTCAGCATG 
AAAGCATCCC TGGAGGGCAA CCTGGCGGAG ACAGAGAACC GCTACTGCGT GCAGCTGTCC 
CAGATCCAGG GGCTGATTGG CAGCGTGGAG GAGCAGCTGG CCCAGCTTCG CTGCGAGATG 
GAGCAGCAGA ACCAGGAATA CAAAATCCTG CTGGATGTGA AGACGCGGCT GGAGCAGGAG 
ATTGCCACCT ACCGCCGCCT GCTGGAGGGA GAGGATGCCC ACCTGACTCA GTACAAGAAA 
GAACCGGTGA CCACCCGTCA GGTGCGTACC ATTGTGGAAG AGGTCCAGGA TGGCAAGGTC 
ATCTCCTCCC GCGAGCAGGT CCACCAGACC ACCCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000413.1
CDS	122..1420
Translation	MTTSIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYKKEPVTTRQVRTIVEEVQDGKVISSREQVHQTTR

Target ORF information:

RefSeq Version	NM_000422.2
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 17 (KRT17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000422.2

ORF Insert Sequence:

ATGACCACCT CCATCCGCCA GTTCACCTCC TCCAGCTCCA TCAAGGGCTC CTCCGGCCTG 
GGGGGCGGCT CGTCCCGCAC CTCCTGCCGG CTGTCTGGCG GCCTGGGTGC CGGCTCCTGC 
AGGCTGGGAT CTGCTGGCGG CCTGGGCAGC ACCCTCGGGG GTAGCAGCTA CTCCAGCTGC 
TACAGCTTTG GCTCTGGTGG TGGCTATGGC AGCAGCTTTG GGGGTGTTGA TGGGCTGCTG 
GCTGGAGGTG AGAAGGCCAC CATGCAGAAC CTCAATGACC GCCTGGCCTC CTACCTGGAC 
AAGGTGCGTG CCCTGGAGGA GGCCAACACT GAGCTGGAGG TGAAGATCCG TGACTGGTAC 
CAGAGGCAGG CCCCGGGGCC CGCCCGTGAC TACAGCCAGT ACTACAGGAC AATTGAGGAG 
CTGCAGAACA AGATCCTCAC AGCCACCGTG GACAATGCCA ACATCCTGCT ACAGATTGAC 
AATGCCCGTC TGGCTGCTGA TGACTTCCGC ACCAAGTTTG AGACAGAGCA GGCCCTGCGC 
CTGAGTGTGG AGGCCGACAT CAATGGCCTG CGCAGGGTGC TGGATGAGCT GACCCTGGCC 
AGAGCCGACC TGGAGATGCA GATTGAGAAC CTCAAGGAGG AGCTGGCCTA CCTGAAGAAG 
AACCACGAGG AGGAGATGAA CGCCCTGCGA GGCCAGGTGG GTGGTGAGAT CAATGTGGAG 
ATGGACGCTG CCCCAGGCGT GGACCTGAGC CGCATCCTCA ACGAGATGCG TGACCAGTAT 
GAGAAGATGG CAGAGAAGAA CCGCAAGGAT GCCGAGGATT GGTTCTTCAG CAAGACAGAG 
GAACTGAACC GCGAGGTGGC CACCAACAGT GAGCTGGTGC AGAGTGGCAA GAGTGAGATC 
TCGGAGCTCC GGCGCACCAT GCAGGCCTTG GAGATAGAGC TGCAGTCCCA GCTCAGCATG 
AAAGCATCCC TGGAGGGCAA CCTGGCGGAG ACAGAGAACC GCTACTGCGT GCAGCTGTCC 
CAGATCCAGG GGCTGATTGG CAGCGTGGAG GAGCAGCTGG CCCAGCTTCG CTGCGAGATG 
GAGCAGCAGA ACCAGGAATA CAAAATCCTG CTGGATGTGA AGACGCGGCT GGAGCAGGAG 
ATTGCCACCT ACCGCCGCCT GCTGGAGGGA GAGGATGCCC ACCTGACTCA GTACAAGAAA 
GAACCGGTGA CCACCCGTCA GGTGCGTACC ATTGTGGAAG AGGTCCAGGA TGGCAAGGTC 
ATCTCCTCCC GCGAGCAGGT CCACCAGACC ACCCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRT17 ( NM_000422.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000413.1 Homo sapiens keratin 17 (KRT17), mRNA.

Price & Availability↑

CloneID	OHu23206
Clone ID Related Accession (Same CDS sequence)	NM_000422.2 , NM_000422.3
Accession Version	NM_000422.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1299bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	keratin, type I cytoskeletal 17
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP226061.1 and BC011901.2. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_000422.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189658.58324.1, SRR5189658.113620.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000311208.13/ ENSP00000308452.8 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACCACCT CCATCCGCCA GTTCACCTCC TCCAGCTCCA TCAAGGGCTC CTCCGGCCTG 
GGGGGCGGCT CGTCCCGCAC CTCCTGCCGG CTGTCTGGCG GCCTGGGTGC CGGCTCCTGC 
AGGCTGGGAT CTGCTGGCGG CCTGGGCAGC ACCCTCGGGG GTAGCAGCTA CTCCAGCTGC 
TACAGCTTTG GCTCTGGTGG TGGCTATGGC AGCAGCTTTG GGGGTGTTGA TGGGCTGCTG 
GCTGGAGGTG AGAAGGCCAC CATGCAGAAC CTCAATGACC GCCTGGCCTC CTACCTGGAC 
AAGGTGCGTG CCCTGGAGGA GGCCAACACT GAGCTGGAGG TGAAGATCCG TGACTGGTAC 
CAGAGGCAGG CCCCGGGGCC CGCCCGTGAC TACAGCCAGT ACTACAGGAC AATTGAGGAG 
CTGCAGAACA AGATCCTCAC AGCCACCGTG GACAATGCCA ACATCCTGCT ACAGATTGAC 
AATGCCCGTC TGGCTGCTGA TGACTTCCGC ACCAAGTTTG AGACAGAGCA GGCCCTGCGC 
CTGAGTGTGG AGGCCGACAT CAATGGCCTG CGCAGGGTGC TGGATGAGCT GACCCTGGCC 
AGAGCCGACC TGGAGATGCA GATTGAGAAC CTCAAGGAGG AGCTGGCCTA CCTGAAGAAG 
AACCACGAGG AGGAGATGAA CGCCCTGCGA GGCCAGGTGG GTGGTGAGAT CAATGTGGAG 
ATGGACGCTG CCCCAGGCGT GGACCTGAGC CGCATCCTCA ACGAGATGCG TGACCAGTAT 
GAGAAGATGG CAGAGAAGAA CCGCAAGGAT GCCGAGGATT GGTTCTTCAG CAAGACAGAG 
GAACTGAACC GCGAGGTGGC CACCAACAGT GAGCTGGTGC AGAGTGGCAA GAGTGAGATC 
TCGGAGCTCC GGCGCACCAT GCAGGCCTTG GAGATAGAGC TGCAGTCCCA GCTCAGCATG 
AAAGCATCCC TGGAGGGCAA CCTGGCGGAG ACAGAGAACC GCTACTGCGT GCAGCTGTCC 
CAGATCCAGG GGCTGATTGG CAGCGTGGAG GAGCAGCTGG CCCAGCTTCG CTGCGAGATG 
GAGCAGCAGA ACCAGGAATA CAAAATCCTG CTGGATGTGA AGACGCGGCT GGAGCAGGAG 
ATTGCCACCT ACCGCCGCCT GCTGGAGGGA GAGGATGCCC ACCTGACTCA GTACAAGAAA 
GAACCGGTGA CCACCCGTCA GGTGCGTACC ATTGTGGAAG AGGTCCAGGA TGGCAAGGTC 
ATCTCCTCCC GCGAGCAGGT CCACCAGACC ACCCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000413.1
CDS	67..1365
Translation	MTTSIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYKKEPVTTRQVRTIVEEVQDGKVISSREQVHQTTR

Target ORF information:

RefSeq Version	NM_000422.3
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 17 (KRT17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000422.3

ORF Insert Sequence:

ATGACCACCT CCATCCGCCA GTTCACCTCC TCCAGCTCCA TCAAGGGCTC CTCCGGCCTG 
GGGGGCGGCT CGTCCCGCAC CTCCTGCCGG CTGTCTGGCG GCCTGGGTGC CGGCTCCTGC 
AGGCTGGGAT CTGCTGGCGG CCTGGGCAGC ACCCTCGGGG GTAGCAGCTA CTCCAGCTGC 
TACAGCTTTG GCTCTGGTGG TGGCTATGGC AGCAGCTTTG GGGGTGTTGA TGGGCTGCTG 
GCTGGAGGTG AGAAGGCCAC CATGCAGAAC CTCAATGACC GCCTGGCCTC CTACCTGGAC 
AAGGTGCGTG CCCTGGAGGA GGCCAACACT GAGCTGGAGG TGAAGATCCG TGACTGGTAC 
CAGAGGCAGG CCCCGGGGCC CGCCCGTGAC TACAGCCAGT ACTACAGGAC AATTGAGGAG 
CTGCAGAACA AGATCCTCAC AGCCACCGTG GACAATGCCA ACATCCTGCT ACAGATTGAC 
AATGCCCGTC TGGCTGCTGA TGACTTCCGC ACCAAGTTTG AGACAGAGCA GGCCCTGCGC 
CTGAGTGTGG AGGCCGACAT CAATGGCCTG CGCAGGGTGC TGGATGAGCT GACCCTGGCC 
AGAGCCGACC TGGAGATGCA GATTGAGAAC CTCAAGGAGG AGCTGGCCTA CCTGAAGAAG 
AACCACGAGG AGGAGATGAA CGCCCTGCGA GGCCAGGTGG GTGGTGAGAT CAATGTGGAG 
ATGGACGCTG CCCCAGGCGT GGACCTGAGC CGCATCCTCA ACGAGATGCG TGACCAGTAT 
GAGAAGATGG CAGAGAAGAA CCGCAAGGAT GCCGAGGATT GGTTCTTCAG CAAGACAGAG 
GAACTGAACC GCGAGGTGGC CACCAACAGT GAGCTGGTGC AGAGTGGCAA GAGTGAGATC 
TCGGAGCTCC GGCGCACCAT GCAGGCCTTG GAGATAGAGC TGCAGTCCCA GCTCAGCATG 
AAAGCATCCC TGGAGGGCAA CCTGGCGGAG ACAGAGAACC GCTACTGCGT GCAGCTGTCC 
CAGATCCAGG GGCTGATTGG CAGCGTGGAG GAGCAGCTGG CCCAGCTTCG CTGCGAGATG 
GAGCAGCAGA ACCAGGAATA CAAAATCCTG CTGGATGTGA AGACGCGGCT GGAGCAGGAG 
ATTGCCACCT ACCGCCGCCT GCTGGAGGGA GAGGATGCCC ACCTGACTCA GTACAAGAAA 
GAACCGGTGA CCACCCGTCA GGTGCGTACC ATTGTGGAAG AGGTCCAGGA TGGCAAGGTC 
ATCTCCTCCC GCGAGCAGGT CCACCAGACC ACCCGCTGA