EBLN1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EBLN1
Entrez Gene ID	340900
Full Name	endogenous Bornavirus like nucleoprotein 1
Synonyms	EBLN-1
General protein information	Preferred Names endogenous Bornavirus like nucleoprotein 1 Names endogenous Bornavirus-like nucleoprotein 1 endogenous Borna-like N element-1 endogenous Borna-like N element-containing protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10p12.31
Disorder MIM:	613249

mRNA and Protein(s)

mRNA	Protein	Name
NM_001199938.1	NP_001186867.1	endogenous Bornavirus-like nucleoprotein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	EBLN1	NP_001186867.1
Pan troglodytes (chimpanzee)	EBLN1	XP_521424.2
Mus musculus (house mouse)	LOC102636291	XP_006534706.1

Gene Ontology
Bibliography

Related articles in PubMed

The bornavirus-derived human protein EBLN1 promotes efficient cell cycle transit, microtubule organisation and genome stability.
Myers KN, Barone G, Ganesh A, Staples CJ, Howard AE, Beveridge RD, Maslen S, Skehel JM, Collis SJ
Scientific reports635548(2016 Oct)

Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat.
Sung YJ, P?russe L, Sarzynski MA, Fornage M, Sidney S, Sternfeld B, Rice T, Terry JG, Jacobs DR Jr, Katzmarzyk P, Curran JE, Jeffrey Carr J, Blangero J, Ghosh S, Despr?s JP, Rankinen T, Rao DC, Bouchard C
International journal of obesity (2005)40(4)662-74(2016 Apr)

Knock-Down of Endogenous Bornavirus-Like Nucleoprotein 1 Inhibits Cell Growth and Induces Apoptosis in Human Oligodendroglia Cells.
He P, Sun L, Zhu D, Zhang H, Zhang L, Guo Y, Liu S, Zhou J, Xu X, Xie P
International journal of molecular sciences17(4)435(2016 Mar)

Comprehensive analysis of endogenous bornavirus-like elements in eukaryote genomes.
Horie M, Kobayashi Y, Suzuki Y, Tomonaga K
Philosophical transactions of the Royal Society of London. Series B, Biological sciences368(1626)20120499(2013 Sep)

No evidence for natural selection on endogenous borna-like nucleoprotein elements after the divergence of Old World and New World monkeys.
Kobayashi Y, Horie M, Tomonaga K, Suzuki Y
PloS one6(9)e24403(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our results provide evidence for new loci influencing abdominal visceral (BBS9, ADCY8, KCNK9) and subcutaneous (MLLT10/DNAJC1/EBLN1) fat, and confirmed a locus (THNSL2) previously reported to be associated with abdominal fat in women.
Title: Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat.

Numerous genes were dysregulated by Endogenous bornavirus-like nucleoprotein 1 silencing, some of which may be key target genes of Rho family GTPase 3, oncostatin M receptor, and cAMP responsive element binding protein 3-like 2 protein.
Title: Knock-Down of Endogenous Bornavirus-Like Nucleoprotein 1 Inhibits Cell Growth and Induces Apoptosis in Human Oligodendroglia Cells.

The following EBLN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EBLN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu01912	NM_001199938.1 Latest version!	Homo sapiens endogenous Bornavirus like nucleoprotein 1 (EBLN1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EBLN1 ( NM_001199938.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186867.1 Homo sapiens endogenous Bornavirus like nucleoprotein 1 (EBLN1), mRNA.

Price & Availability↑

CloneID	OHu01912
Clone ID Related Accession (Same CDS sequence)	NM_001199938.1
Accession Version	NM_001199938.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1101bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	endogenous Bornavirus-like nucleoprotein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL157831.29. On or before Jan 21, 2011 this sequence version replaced XM_291767.4, XM_939479.2, XM_001716722.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGTCCCGCC CAAGAAACAA CCCACAGACC AGCAGCCCAC AAGACAGTAC AAAGGATGGG 
AGCAGCTTCC ATTACTTTCA AGGGAGATTT GAGCTCTCTG GGAAGAGCAG ACAGTATCCA 
GCAGATGCAT TGGAGCCCCA ACCTGGTATT GGAGATGTTA AGGTCATTGA AAAAGCAACT 
AAGTCTATGC TAGACCCAGC ACAGAGATCT CATTTTTACC TTGTAACCCC AAGCTTAGTA 
TTTTTGTGTT TTATATTCGA TGGATTACAC AAGGCACTAC TCAGTGTCGG TGTGAGCAAA 
AGGTCTAATA TTGTGATTGG GAATGAGAAC AAGGAAACAG GTACTCTCTA TGCTAGCAAA 
TTTGAAGATG TTTTGCCTAC CTTCACTGCC CTTGAGATGT CATCAATTCT GCGTCACTGC 
TGTGATCTGA TAGGCATTGC TGCCGGATCG AGTGACCCGA TATGCACCAA CAGCCTCCAA 
GTACAGAGAC AATTCAAGGC AATGATGATA TCCATTGGAA GACCTTTGCA TAGTGAAAGT 
GCTGATTTAT TAATTAGCTA TAATGCAGGG CCAGCTATAG ATTGGATCAA CTCAAGACCA 
TGGGTTGGAG GATTAATGTT CACATTTCTA TTTGGAGAAT TTGAATCCCC TGCGTGCGAG 
CTACTTGATC AAGTTAAAGT AGTTGCCAGC AAAGCACAGA TGATGACCTA CTACACTGTG 
AGAATGTTCC TGGATCAGTG TGTGGATGGT TCCACTGCTT TACCCGCTGT TGTGTTGGAG 
ATTCCAGTTT TTGAGCAGAA GAAACCACTG GCTAAAAAGG TACTTGGAGA TTTCTTTGAA 
TTTGGGGGTG TACTTCGCCA CCCTGTTATT GGGGTGCTAT CACCACAAAT GTTCCCAAAC 
CTAGCAACAG CAGCAAACTA CTGGGCCAAA AGAAGGAATT CCACATTTTC TGGATTTGAA 
GCCCTTGACA TTATACCAGG ATCAACTATT ACATTCCCTG TACTTCAAAT GGCATCTGCT 
CAGAAAATCT CCAGAGGAAG TGACATGGAT CCATATACAC TTAACATCCT TCGCGGTTAT 
GGGATTTCGG GATTTGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186867.1
CDS	1..1101
Translation	MSRPRNNPQTSSPQDSTKDGSSFHYFQGRFELSGKSRQYPADALEPQPGIGDVKVIEKATKSMLDPAQRSHFYLVTPSLVFLCFIFDGLHKALLSVGVSKRSNIVIGNENKETGTLYASKFEDVLPTFTALEMSSILRHCCDLIGIAAGSSDPICTNSLQVQRQFKAMMISIGRPLHSESADLLISYNAGPAIDWINSRPWVGGLMFTFLFGEFESPACELLDQVKVVASKAQMMTYYTVRMFLDQCVDGSTALPAVVLEIPVFEQKKPLAKKVLGDFFEFGGVLRHPVIGVLSPQMFPNLATAANYWAKRRNSTFSGFEALDIIPGSTITFPVLQMASAQKISRGSDMDPYTLNILRGYGISGFE

Target ORF information:

RefSeq Version	NM_001199938.1
Organism	Homo sapiens(human)
Definition	Homo sapiens endogenous Bornavirus like nucleoprotein 1 (EBLN1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199938.1

ORF Insert Sequence:

ATGTCCCGCC CAAGAAACAA CCCACAGACC AGCAGCCCAC AAGACAGTAC AAAGGATGGG 
AGCAGCTTCC ATTACTTTCA AGGGAGATTT GAGCTCTCTG GGAAGAGCAG ACAGTATCCA 
GCAGATGCAT TGGAGCCCCA ACCTGGTATT GGAGATGTTA AGGTCATTGA AAAAGCAACT 
AAGTCTATGC TAGACCCAGC ACAGAGATCT CATTTTTACC TTGTAACCCC AAGCTTAGTA 
TTTTTGTGTT TTATATTCGA TGGATTACAC AAGGCACTAC TCAGTGTCGG TGTGAGCAAA 
AGGTCTAATA TTGTGATTGG GAATGAGAAC AAGGAAACAG GTACTCTCTA TGCTAGCAAA 
TTTGAAGATG TTTTGCCTAC CTTCACTGCC CTTGAGATGT CATCAATTCT GCGTCACTGC 
TGTGATCTGA TAGGCATTGC TGCCGGATCG AGTGACCCGA TATGCACCAA CAGCCTCCAA 
GTACAGAGAC AATTCAAGGC AATGATGATA TCCATTGGAA GACCTTTGCA TAGTGAAAGT 
GCTGATTTAT TAATTAGCTA TAATGCAGGG CCAGCTATAG ATTGGATCAA CTCAAGACCA 
TGGGTTGGAG GATTAATGTT CACATTTCTA TTTGGAGAAT TTGAATCCCC TGCGTGCGAG 
CTACTTGATC AAGTTAAAGT AGTTGCCAGC AAAGCACAGA TGATGACCTA CTACACTGTG 
AGAATGTTCC TGGATCAGTG TGTGGATGGT TCCACTGCTT TACCCGCTGT TGTGTTGGAG 
ATTCCAGTTT TTGAGCAGAA GAAACCACTG GCTAAAAAGG TACTTGGAGA TTTCTTTGAA 
TTTGGGGGTG TACTTCGCCA CCCTGTTATT GGGGTGCTAT CACCACAAAT GTTCCCAAAC 
CTAGCAACAG CAGCAAACTA CTGGGCCAAA AGAAGGAATT CCACATTTTC TGGATTTGAA 
GCCCTTGACA TTATACCAGG ATCAACTATT ACATTCCCTG TACTTCAAAT GGCATCTGCT 
CAGAAAATCT CCAGAGGAAG TGACATGGAT CCATATACAC TTAACATCCT TCGCGGTTAT 
GGGATTTCGG GATTTGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The bornavirus-derived human protein EBLN1 promotes efficient cell cycle transit, microtubule organisation and genome stability.
Scientific reports635548(2016 Oct)
Myers KN,Barone G,Ganesh A,Staples CJ,Howard AE,Beveridge RD,Maslen S,Skehel JM,Collis SJ

Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat.
International journal of obesity (2005)40(4)662-74(2016 Apr)
Sung YJ,P?russe L,Sarzynski MA,Fornage M,Sidney S,Sternfeld B,Rice T,Terry JG,Jacobs DR Jr,Katzmarzyk P,Curran JE,Jeffrey Carr J,Blangero J,Ghosh S,Despr?s JP,Rankinen T,Rao DC,Bouchard C

Knock-Down of Endogenous Bornavirus-Like Nucleoprotein 1 Inhibits Cell Growth and Induces Apoptosis in Human Oligodendroglia Cells.
International journal of molecular sciences17(4)435(2016 Mar)
He P,Sun L,Zhu D,Zhang H,Zhang L,Guo Y,Liu S,Zhou J,Xu X,Xie P

Comprehensive analysis of endogenous bornavirus-like elements in eukaryote genomes.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences368(1626)20120499(2013 Sep)
Horie M,Kobayashi Y,Suzuki Y,Tomonaga K

No evidence for natural selection on endogenous borna-like nucleoprotein elements after the divergence of Old World and New World monkeys.
PloS one6(9)e24403(2011)
Kobayashi Y,Horie M,Tomonaga K,Suzuki Y