HTR6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HTR6
Entrez Gene ID	3362
Full Name	5-hydroxytryptamine receptor 6
Synonyms	5-HT6,5-HT6R
General protein information	Preferred Names 5-hydroxytryptamine receptor 6 Names 5-hydroxytryptamine receptor 6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled serotonin receptor 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.13
Summary	This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013].
Disorder MIM:	601109

mRNA and Protein(s)

mRNA	Protein	Name
NM_000871.2	NP_000862.1	5-hydroxytryptamine receptor 6
NM_000871.3	NP_000862.1	5-hydroxytryptamine receptor 6

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Htr6	NP_067333.1
Rattus norvegicus (Norway rat)	Htr6	NP_077341.1
Danio rerio (zebrafish)	LOC568269	XP_696681.5
Bos taurus (cattle)	HTR6	NP_001192646.1
Homo sapiens (human)	HTR6	NP_000862.1
Pan troglodytes (chimpanzee)	HTR6	NP_001029264.1
	LOC716776	XP_001107724.2
Gallus gallus (chicken)	HTR6	NP_001166911.1
Xenopus tropicalis (tropical clawed frog)	htr6	XP_002942005.2
Canis lupus familiaris (dog)	HTR6	XP_544528.4

Gene Ontology
Bibliography

Related articles in PubMed

Serotonin 6 receptor controls Alzheimer's disease and depression.
Yun HM, Park KR, Kim EC, Kim S, Hong JT
Oncotarget6(29)26716-28(2015 Sep)

5-HT6 Receptor Recruitment of mTOR Modulates Seizure Activity in Epilepsy.
Wang L, Lv Y, Deng W, Peng X, Xiao Z, Xi Z, Chen G, Wang X
Molecular neurobiology51(3)1292-9(2015)

Serotonin 5-HT6 receptor antagonists for the treatment of cognitive deficiency in Alzheimer's disease.
Benham? B, Mart?n-Fontecha M, V?zquez-Villa H, Pardo L, L?pez-Rodr?guez ML
Journal of medicinal chemistry57(17)7160-81(2014 Sep)

Improving the treatment of schizophrenia: role of 5-HT receptors in modulating cognitive and extrapyramidal motor functions.
Shimizu S, Mizuguchi Y, Ohno Y
CNS & neurological disorders drug targets12(6)861-9(2013 Sep)

Structure-activity relationship of 5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole analogues as 5-HT(6) receptor agonists.
Mattsson C, Svensson P, Boettcher H, Sonesson C
European journal of medicinal chemistry63578-88(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Serotonin 6 receptor has a role in Alzheimer's disease and depression
Title: Serotonin 6 receptor controls Alzheimer's disease and depression.

that HTR6 plays an important role in modulating seizure activity and that the blockade of the 5-HT6 receptor/mTOR pathway could be a potential therapeutic target for epilepsy treatment
Title: 5-HT6 Receptor Recruitment of mTOR Modulates Seizure Activity in Epilepsy.

Studies indicate that serotonin 5-HT6 receptor (5-HT6R) has been proposed as a promising drug target for cognition enhancement in Alzheimer's disease (AD).
Title: Serotonin 5-HT6 receptor antagonists for the treatment of cognitive deficiency in Alzheimer's disease.

[review] Controlling the activity of 5-HTR6 receptors seems to provide benefits by alleviating cognitive impairments.
Title: Improving the treatment of schizophrenia: role of 5-HT receptors in modulating cognitive and extrapyramidal motor functions.

Data indicate that hydrogen-bond formation of a methoxy or hydroxy group is not important for binding at the 5-HT6 receptor.
Title: Structure-activity relationship of 5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole analogues as 5-HT(6) receptor agonists.

The following HTR6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HTR6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23974	NM_000871.3 Latest version!	Homo sapiens 5-hydroxytryptamine receptor 6 (HTR6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu23974	NM_000871.2	Homo sapiens 5-hydroxytryptamine receptor 6 (HTR6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HTR6 ( NM_000871.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_000862.1 Homo sapiens 5-hydroxytryptamine receptor 6 (HTR6), mRNA.

Price & Availability↑

CloneID	OHu23974
Clone ID Related Accession (Same CDS sequence)	NM_000871.2 , NM_000871.3
Accession Version	NM_000871.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1323bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	5-hydroxytryptamine receptor 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L41147.1, AL031727.43 and AF007141.1. On Aug 30, 2013 this sequence version replaced NM_000871.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L41147.1, BC074995.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCCCAG AGCCGGGCCC AACCGCCAAT AGCACCCCGG CCTGGGGGGC AGGGCCGCCG 
TCGGCCCCGG GGGGCAGCGG CTGGGTGGCG GCCGCGCTGT GCGTGGTCAT CGCGCTGACG 
GCGGCGGCCA ACTCGCTGCT GATCGCGCTC ATCTGCACTC AGCCCGCGCT GCGCAACACG 
TCCAACTTCT TCCTGGTGTC GCTCTTCACG TCTGACCTGA TGGTGGGGCT GGTGGTGATG 
CCGCCGGCCA TGCTGAACGC GCTGTACGGG CGCTGGGTGC TGGCGCGCGG CCTCTGCCTG 
CTCTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TCCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACGCCC 
CTGCGTGCCC TGGCCCTAGT CCTGGGCGCC TGGAGCCTCG CCGCTCTCGC CTCCTTCCTG 
CCCCTGCTGC TGGGCTGGCA CGAGCTGGGC CACGCACGGC CACCCGTCCC TGGCCAGTGC 
CGCCTGCTGG CCAGCCTGCC TTTTGTCCTT GTGGCGTCGG GCCTCACCTT CTTCCTGCCC 
TCGGGTGCCA TATGCTTCAC CTACTGCAGG ATCCTGCTAG CTGCCCGCAA GCAGGCCGTG 
CAGGTGGCCT CCCTCACCAC CGGCATGGCC AGTCAGGCCT CGGAGACGCT GCAGGTGCCC 
AGGACCCCAC GCCCAGGGGT GGAGTCTGCT GACAGCAGGC GTCTAGCCAC GAAGCACAGC 
AGGAAGGCCC TGAAGGCCAG CCTGACGCTG GGCATCCTGC TGGGCATGTT CTTTGTGACC 
TGGTTGCCCT TCTTTGTGGC CAACATAGTC CAGGCCGTGT GCGACTGCAT CTCCCCAGGC 
CTCTTCGATG TCCTCACATG GCTGGGTTAC TGTAACAGCA CCATGAACCC CATCATCTAC 
CCACTCTTCA TGCGGGACTT CAAGCGGGCG CTGGGCAGGT TCCTGCCATG TCCACGCTGT 
CCCCGGGAGC GCCAGGCCAG CCTGGCCTCG CCATCACTGC GCACCTCTCA CAGCGGCCCC 
CGGCCCGGCC TTAGCCTACA GCAGGTGCTG CCGCTGCCCC TGCCGCCGGA CTCAGATTCG 
GACTCAGACG CAGGCTCAGG CGGCTCCTCG GGCCTGCGGC TCACGGCCCA GCTGCTGCTT 
CCTGGCGAGG CCACCCAGGA CCCCCCGCTG CCCACCAGGG CCGCTGCCGC CGTCAATTTC 
TTCAACATCG ACCCCGCGGA GCCCGAGCTG CGGCCGCATC CACTTGGCAT CCCCACGAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000862.1
CDS	468..1790
Translation	MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN

Target ORF information:

RefSeq Version	NM_000871.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 5-hydroxytryptamine receptor 6 (HTR6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000871.2

ORF Insert Sequence:

ATGGTCCCAG AGCCGGGCCC AACCGCCAAT AGCACCCCGG CCTGGGGGGC AGGGCCGCCG 
TCGGCCCCGG GGGGCAGCGG CTGGGTGGCG GCCGCGCTGT GCGTGGTCAT CGCGCTGACG 
GCGGCGGCCA ACTCGCTGCT GATCGCGCTC ATCTGCACTC AGCCCGCGCT GCGCAACACG 
TCCAACTTCT TCCTGGTGTC GCTCTTCACG TCTGACCTGA TGGTGGGGCT GGTGGTGATG 
CCGCCGGCCA TGCTGAACGC GCTGTACGGG CGCTGGGTGC TGGCGCGCGG CCTCTGCCTG 
CTCTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TCCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACGCCC 
CTGCGTGCCC TGGCCCTAGT CCTGGGCGCC TGGAGCCTCG CCGCTCTCGC CTCCTTCCTG 
CCCCTGCTGC TGGGCTGGCA CGAGCTGGGC CACGCACGGC CACCCGTCCC TGGCCAGTGC 
CGCCTGCTGG CCAGCCTGCC TTTTGTCCTT GTGGCGTCGG GCCTCACCTT CTTCCTGCCC 
TCGGGTGCCA TATGCTTCAC CTACTGCAGG ATCCTGCTAG CTGCCCGCAA GCAGGCCGTG 
CAGGTGGCCT CCCTCACCAC CGGCATGGCC AGTCAGGCCT CGGAGACGCT GCAGGTGCCC 
AGGACCCCAC GCCCAGGGGT GGAGTCTGCT GACAGCAGGC GTCTAGCCAC GAAGCACAGC 
AGGAAGGCCC TGAAGGCCAG CCTGACGCTG GGCATCCTGC TGGGCATGTT CTTTGTGACC 
TGGTTGCCCT TCTTTGTGGC CAACATAGTC CAGGCCGTGT GCGACTGCAT CTCCCCAGGC 
CTCTTCGATG TCCTCACATG GCTGGGTTAC TGTAACAGCA CCATGAACCC CATCATCTAC 
CCACTCTTCA TGCGGGACTT CAAGCGGGCG CTGGGCAGGT TCCTGCCATG TCCACGCTGT 
CCCCGGGAGC GCCAGGCCAG CCTGGCCTCG CCATCACTGC GCACCTCTCA CAGCGGCCCC 
CGGCCCGGCC TTAGCCTACA GCAGGTGCTG CCGCTGCCCC TGCCGCCGGA CTCAGATTCG 
GACTCAGACG CAGGCTCAGG CGGCTCCTCG GGCCTGCGGC TCACGGCCCA GCTGCTGCTT 
CCTGGCGAGG CCACCCAGGA CCCCCCGCTG CCCACCAGGG CCGCTGCCGC CGTCAATTTC 
TTCAACATCG ACCCCGCGGA GCCCGAGCTG CGGCCGCATC CACTTGGCAT CCCCACGAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HTR6 ( NM_000871.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000862.1 Homo sapiens 5-hydroxytryptamine receptor 6 (HTR6), mRNA.

Price & Availability↑

CloneID	OHu23974
Clone ID Related Accession (Same CDS sequence)	NM_000871.2 , NM_000871.3
Accession Version	NM_000871.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1323bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	5-hydroxytryptamine receptor 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL031727.43, L41147.1 and AF007141.1. On Nov 23, 2018 this sequence version replaced NM_000871.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L41147.1, BC074995.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000289753.2/ ENSP00000289753.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTCCCAG AGCCGGGCCC AACCGCCAAT AGCACCCCGG CCTGGGGGGC AGGGCCGCCG 
TCGGCCCCGG GGGGCAGCGG CTGGGTGGCG GCCGCGCTGT GCGTGGTCAT CGCGCTGACG 
GCGGCGGCCA ACTCGCTGCT GATCGCGCTC ATCTGCACTC AGCCCGCGCT GCGCAACACG 
TCCAACTTCT TCCTGGTGTC GCTCTTCACG TCTGACCTGA TGGTGGGGCT GGTGGTGATG 
CCGCCGGCCA TGCTGAACGC GCTGTACGGG CGCTGGGTGC TGGCGCGCGG CCTCTGCCTG 
CTCTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TCCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACGCCC 
CTGCGTGCCC TGGCCCTAGT CCTGGGCGCC TGGAGCCTCG CCGCTCTCGC CTCCTTCCTG 
CCCCTGCTGC TGGGCTGGCA CGAGCTGGGC CACGCACGGC CACCCGTCCC TGGCCAGTGC 
CGCCTGCTGG CCAGCCTGCC TTTTGTCCTT GTGGCGTCGG GCCTCACCTT CTTCCTGCCC 
TCGGGTGCCA TATGCTTCAC CTACTGCAGG ATCCTGCTAG CTGCCCGCAA GCAGGCCGTG 
CAGGTGGCCT CCCTCACCAC CGGCATGGCC AGTCAGGCCT CGGAGACGCT GCAGGTGCCC 
AGGACCCCAC GCCCAGGGGT GGAGTCTGCT GACAGCAGGC GTCTAGCCAC GAAGCACAGC 
AGGAAGGCCC TGAAGGCCAG CCTGACGCTG GGCATCCTGC TGGGCATGTT CTTTGTGACC 
TGGTTGCCCT TCTTTGTGGC CAACATAGTC CAGGCCGTGT GCGACTGCAT CTCCCCAGGC 
CTCTTCGATG TCCTCACATG GCTGGGTTAC TGTAACAGCA CCATGAACCC CATCATCTAC 
CCACTCTTCA TGCGGGACTT CAAGCGGGCG CTGGGCAGGT TCCTGCCATG TCCACGCTGT 
CCCCGGGAGC GCCAGGCCAG CCTGGCCTCG CCATCACTGC GCACCTCTCA CAGCGGCCCC 
CGGCCCGGCC TTAGCCTACA GCAGGTGCTG CCGCTGCCCC TGCCGCCGGA CTCAGATTCG 
GACTCAGACG CAGGCTCAGG CGGCTCCTCG GGCCTGCGGC TCACGGCCCA GCTGCTGCTT 
CCTGGCGAGG CCACCCAGGA CCCCCCGCTG CCCACCAGGG CCGCTGCCGC CGTCAATTTC 
TTCAACATCG ACCCCGCGGA GCCCGAGCTG CGGCCGCATC CACTTGGCAT CCCCACGAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000862.1
CDS	880..2202
Translation	MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN

Target ORF information:

RefSeq Version	NM_000871.3
Organism	Homo sapiens(human)
Definition	Homo sapiens 5-hydroxytryptamine receptor 6 (HTR6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000871.3

ORF Insert Sequence:

ATGGTCCCAG AGCCGGGCCC AACCGCCAAT AGCACCCCGG CCTGGGGGGC AGGGCCGCCG 
TCGGCCCCGG GGGGCAGCGG CTGGGTGGCG GCCGCGCTGT GCGTGGTCAT CGCGCTGACG 
GCGGCGGCCA ACTCGCTGCT GATCGCGCTC ATCTGCACTC AGCCCGCGCT GCGCAACACG 
TCCAACTTCT TCCTGGTGTC GCTCTTCACG TCTGACCTGA TGGTGGGGCT GGTGGTGATG 
CCGCCGGCCA TGCTGAACGC GCTGTACGGG CGCTGGGTGC TGGCGCGCGG CCTCTGCCTG 
CTCTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TCCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACGCCC 
CTGCGTGCCC TGGCCCTAGT CCTGGGCGCC TGGAGCCTCG CCGCTCTCGC CTCCTTCCTG 
CCCCTGCTGC TGGGCTGGCA CGAGCTGGGC CACGCACGGC CACCCGTCCC TGGCCAGTGC 
CGCCTGCTGG CCAGCCTGCC TTTTGTCCTT GTGGCGTCGG GCCTCACCTT CTTCCTGCCC 
TCGGGTGCCA TATGCTTCAC CTACTGCAGG ATCCTGCTAG CTGCCCGCAA GCAGGCCGTG 
CAGGTGGCCT CCCTCACCAC CGGCATGGCC AGTCAGGCCT CGGAGACGCT GCAGGTGCCC 
AGGACCCCAC GCCCAGGGGT GGAGTCTGCT GACAGCAGGC GTCTAGCCAC GAAGCACAGC 
AGGAAGGCCC TGAAGGCCAG CCTGACGCTG GGCATCCTGC TGGGCATGTT CTTTGTGACC 
TGGTTGCCCT TCTTTGTGGC CAACATAGTC CAGGCCGTGT GCGACTGCAT CTCCCCAGGC 
CTCTTCGATG TCCTCACATG GCTGGGTTAC TGTAACAGCA CCATGAACCC CATCATCTAC 
CCACTCTTCA TGCGGGACTT CAAGCGGGCG CTGGGCAGGT TCCTGCCATG TCCACGCTGT 
CCCCGGGAGC GCCAGGCCAG CCTGGCCTCG CCATCACTGC GCACCTCTCA CAGCGGCCCC 
CGGCCCGGCC TTAGCCTACA GCAGGTGCTG CCGCTGCCCC TGCCGCCGGA CTCAGATTCG 
GACTCAGACG CAGGCTCAGG CGGCTCCTCG GGCCTGCGGC TCACGGCCCA GCTGCTGCTT 
CCTGGCGAGG CCACCCAGGA CCCCCCGCTG CCCACCAGGG CCGCTGCCGC CGTCAATTTC 
TTCAACATCG ACCCCGCGGA GCCCGAGCTG CGGCCGCATC CACTTGGCAT CCCCACGAAC 
TGA