SLC41A1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC41A1
Entrez Gene ID	254428
Full Name	solute carrier family 41 member 1
Synonyms	MgtE
General protein information	Preferred Names solute carrier family 41 member 1 Names solute carrier family 41 member 1 solute carrier family 41 (magnesium transporter), member 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q32.1
Disorder MIM:	610801

mRNA and Protein(s)

mRNA	Protein	Name
NM_173854.5	NP_776253.3	solute carrier family 41 member 1
NM_173854.6	NP_776253.3	solute carrier family 41 member 1
XM_005245069.2	XP_005245126.1	solute carrier family 41 member 1 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SLC41A1	XP_005640855.1
Mus musculus (house mouse)	Slc41a1	NP_776290.1
Xenopus tropicalis (tropical clawed frog)	slc41a1	XP_004910709.1
Bos taurus (cattle)	SLC41A1	NP_001192965.1
	SLC41A1	XP_001091472.1
Caenorhabditis elegans (roundworm)	K07H8.2	NP_501393.1
Homo sapiens (human)	SLC41A1	NP_776253.3
Pan troglodytes (chimpanzee)	SLC41A1	XP_003308716.1
Rattus norvegicus (Norway rat)	Slc41a1	NP_001102325.1
Gallus gallus (chicken)	SLC41A1	XP_417968.2
Danio rerio (zebrafish)	slc41a1	XP_002663867.1

Gene Ontology
Bibliography

Related articles in PubMed

Knockdown of SLC41A1 magnesium transporter promotes mineralization and attenuates magnesium inhibition during osteogenesis of mesenchymal stromal cells.
Tsao YT, Shih YY, Liu YA, Liu YS, Lee OK
Stem cell research & therapy8(1)39(2017 02)

Genetic Analysis of the ZNF512B, SLC41A1, and ALDH2 Polymorphisms in Parkinson's Disease in the ian Population.
Madadi F, Khaniani MS, Shandiz EE, Ayromlou H, Najmi S, Emamalizadeh B, Taghavi S, Jamshidi J, Tafakhori A, Shahidi GA, Darvish H
Genetic testing and molecular biomarkers20(10)629-632(2016 Oct)

Genetic analysis of SLC41A1 in Chinese Parkinson's disease patients.
Wang L, Cheng L, Li NN, Yu WJ, Sun XY, Peng R
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics168(8)706-11(2015 Dec)

Insulin Modulates the Na+/Mg2+ Exchanger SLC41A1 and Influences Mg2+ Efflux from Intracellular Stores in Transgenic HEK293 Cells.
Mastrototaro L, Tietjen U, Sponder G, Vormann J, Aschenbach JR, Kolisek M
The Journal of nutrition145(11)2440-7(2015 Nov)

Genetic variants at 1q32.1, 10q11.2 and 19q13.41 are associated with prostate-specific antigen for prostate cancer screening in two Korean population-based cohort studies.
Kim S, Shin C, Jee SH
Gene556(2)199-205(2015 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Knockdown of SLC41A1 magnesium transporter promotes mineralization and attenuates magnesium inhibition during osteogenesis of mesenchymal stromal cells.
Title: Knockdown of SLC41A1 magnesium transporter promotes mineralization and attenuates magnesium inhibition during osteogenesis of mesenchymal stromal cells.

The association of rs11240569 polymorphism in SLC41A1 gene with reduced risk of Parkinson's Disease was replicated in our population.
Title: Genetic Analysis of the ZNF512B, SLC41A1, and ALDH2 Polymorphisms in Parkinson's Disease in the ian Population.

Authors performed direct DNA sequencing of the SLC41A1 gene in 100 early-onset PD cases.
Title: Genetic analysis of SLC41A1 in Chinese Parkinson's disease patients.

Na+-dependent Mg2+ efflux conducted by Na+/Mg2+ exchanger SLC41A1 is regulated by insulin.
Title: Insulin Modulates the Na+/Mg2+ Exchanger SLC41A1 and Influences Mg2+ Efflux from Intracellular Stores in Transgenic HEK293 Cells.

This study has shown loss of Mg(2+) efflux function consequent to SLC41A1 R244H variant and SLC41A1 coding variants seem to be rare in Taiwanese Parkinson disease.
Title: Variant R244H in Na+/Mg2+ exchanger SLC41A1 in Taiwanese Parkinson's disease is associated with loss of Mg2+ efflux function.

The following SLC41A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC41A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15881	NM_173854.6 Latest version!	Homo sapiens solute carrier family 41 member 1 (SLC41A1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu15881	XM_005245069.2 Latest version!	Homo sapiens solute carrier family 41 member 1 (SLC41A1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
View Old Accession Versions >>
OHu15881	NM_173854.5	Homo sapiens solute carrier family 41 member 1 (SLC41A1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC41A1 ( NM_173854.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_776253.3 Homo sapiens solute carrier family 41 member 1 (SLC41A1), mRNA.

Price & Availability↑

CloneID	OHu15881
Clone ID Related Accession (Same CDS sequence)	NM_173854.5 , NM_173854.6 , XM_005245069.2
Accession Version	NM_173854.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-12
Organism	Homo sapiens(human)
Product	solute carrier family 41 member 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY148928.1, DA496198.1, BX641054.1, BC136303.1 and BX648979.1. On Jan 31, 2015 this sequence version replaced NM_173854.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX648979.1, AL831974.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCTCTA AGCCAGAGCC GAAGGACGTC CACCAACTGA ACGGGACTGG CCCTTCTGCC 
TCTCCCTGCT CTTCAGATGG CCCAGGGAGA GAGCCCTTGG CTGGGACCTC AGAGTTCCTG 
GGGCCTGATG GGGCTGGGGT AGAGGTGGTG ATTGAGTCTC GGGCCAACGC CAAGGGGGTT 
CGGGAGGAGG ACGCCCTGCT GGAGAACGGG AGCCAGAGCA ACGAAAGTGA CGACGTCAGC 
ACAGACCGTG GCCCTGCGCC ACCTTCCCCG CTCAAGGAGA CCTCCTTTTC CATCGGGCTG 
CAAGTACTGT TTCCATTCCT CCTGGCAGGC TTTGGGACCG TGGCTGCTGG CATGGTGTTG 
GACATCGTGC AGCACTGGGA AGTCTTCCAG AAGGTGACAG AGGTCTTCAT CCTAGTGCCT 
GCGCTGCTGG GGCTCAAAGG GAACCTGGAA ATGACCCTGG CATCAAGGCT TTCCACTGCA 
GCCAACATTG GACACATGGA CACACCCAAG GAGCTCTGGC GGATGATCAC TGGGAACATG 
GCCCTCATCC AGGTGCAGGC CACGGTGGTG GGCTTCCTGG CGTCCATCGC AGCCGTCGTC 
TTTGGCTGGA TCCCTGATGG CCACTTCAGT ATTCCGCACG CCTTCCTGCT CTGTGCTAGC 
AGCGTGGCCA CAGCCTTCAT TGCCTCCCTG GTACTGGGTA TGATCATGAT TGGAGTCATC 
ATTGGCTCTC GCAAGATTGG GATCAACCCA GACAACGTGG CCACACCCAT TGCTGCCAGC 
CTGGGCGACC TCATCACCTT GGCGCTGCTC TCAGGCATCA GCTGGGGACT CTACCTGGAA 
CTGAATCACT GGCGATACAT CTACCCACTG GTGTGTGCTT TCTTTGTGGC CCTGCTGCCT 
GTCTGGGTGG TGCTGGCCCG ACGAAGTCCA GCCACAAGGG AGGTGTTGTA CTCGGGCTGG 
GAGCCTGTTA TCATTGCCAT GGCCATCAGC AGTGTGGGAG GCCTCATCTT GGACAAGACT 
GTCTCAGACC CCAACTTTGC TGGGATGGCT GTCTTCACGC CTGTGATTAA TGGTGTTGGG 
GGCAATCTGG TGGCAGTGCA GGCCAGCCGC ATCTCCACCT TCCTGCACAT GAATGGAATG 
CCCGGAGAGA ACTCTGAGCA AGCTCCTCGC CGCTGTCCCA GTCCTTGTAC CACCTTCTTC 
AGCCCTGATG TGAATTCTCG CTCAGCCCGG GTCCTCTTCC TCCTCGTGGT CCCAGGACAC 
CTGGTGTTCC TCTACACCAT CAGCTGTATG CAGGGCGGGC ACACCACCCT CACACTCATC 
TTCATCATCT TCTATATGAC AGCTGCACTG CTCCAGGTGC TGATTCTCCT GTACATCGCA 
GACTGGATGG TGCACTGGAT GTGGGGCCGG GGCCTGGACC CGGACAACTT CTCCATCCCA 
TACTTGACTG CTCTGGGGGA CCTGCTTGGC ACTGGGCTCC TAGCACTCAG CTTCCATGTT 
CTCTGGCTCA TAGGGGACCG AGACACGGAT GTCGGGGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776253.3
CDS	1036..2577
Translation	MSSKPEPKDVHQLNGTGPSASPCSSDGPGREPLAGTSEFLGPDGAGVEVVIESRANAKGVREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELNHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQAPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD

Target ORF information:

RefSeq Version	NM_173854.5
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 41 member 1 (SLC41A1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173854.5

ORF Insert Sequence:

ATGTCCTCTA AGCCAGAGCC GAAGGACGTC CACCAACTGA ACGGGACTGG CCCTTCTGCC 
TCTCCCTGCT CTTCAGATGG CCCAGGGAGA GAGCCCTTGG CTGGGACCTC AGAGTTCCTG 
GGGCCTGATG GGGCTGGGGT AGAGGTGGTG ATTGAGTCTC GGGCCAACGC CAAGGGGGTT 
CGGGAGGAGG ACGCCCTGCT GGAGAACGGG AGCCAGAGCA ACGAAAGTGA CGACGTCAGC 
ACAGACCGTG GCCCTGCGCC ACCTTCCCCG CTCAAGGAGA CCTCCTTTTC CATCGGGCTG 
CAAGTACTGT TTCCATTCCT CCTGGCAGGC TTTGGGACCG TGGCTGCTGG CATGGTGTTG 
GACATCGTGC AGCACTGGGA AGTCTTCCAG AAGGTGACAG AGGTCTTCAT CCTAGTGCCT 
GCGCTGCTGG GGCTCAAAGG GAACCTGGAA ATGACCCTGG CATCAAGGCT TTCCACTGCA 
GCCAACATTG GACACATGGA CACACCCAAG GAGCTCTGGC GGATGATCAC TGGGAACATG 
GCCCTCATCC AGGTGCAGGC CACGGTGGTG GGCTTCCTGG CGTCCATCGC AGCCGTCGTC 
TTTGGCTGGA TCCCTGATGG CCACTTCAGT ATTCCGCACG CCTTCCTGCT CTGTGCTAGC 
AGCGTGGCCA CAGCCTTCAT TGCCTCCCTG GTACTGGGTA TGATCATGAT TGGAGTCATC 
ATTGGCTCTC GCAAGATTGG GATCAACCCA GACAACGTGG CCACACCCAT TGCTGCCAGC 
CTGGGCGACC TCATCACCTT GGCGCTGCTC TCAGGCATCA GCTGGGGACT CTACCTGGAA 
CTGAATCACT GGCGATACAT CTACCCACTG GTGTGTGCTT TCTTTGTGGC CCTGCTGCCT 
GTCTGGGTGG TGCTGGCCCG ACGAAGTCCA GCCACAAGGG AGGTGTTGTA CTCGGGCTGG 
GAGCCTGTTA TCATTGCCAT GGCCATCAGC AGTGTGGGAG GCCTCATCTT GGACAAGACT 
GTCTCAGACC CCAACTTTGC TGGGATGGCT GTCTTCACGC CTGTGATTAA TGGTGTTGGG 
GGCAATCTGG TGGCAGTGCA GGCCAGCCGC ATCTCCACCT TCCTGCACAT GAATGGAATG 
CCCGGAGAGA ACTCTGAGCA AGCTCCTCGC CGCTGTCCCA GTCCTTGTAC CACCTTCTTC 
AGCCCTGATG TGAATTCTCG CTCAGCCCGG GTCCTCTTCC TCCTCGTGGT CCCAGGACAC 
CTGGTGTTCC TCTACACCAT CAGCTGTATG CAGGGCGGGC ACACCACCCT CACACTCATC 
TTCATCATCT TCTATATGAC AGCTGCACTG CTCCAGGTGC TGATTCTCCT GTACATCGCA 
GACTGGATGG TGCACTGGAT GTGGGGCCGG GGCCTGGACC CGGACAACTT CTCCATCCCA 
TACTTGACTG CTCTGGGGGA CCTGCTTGGC ACTGGGCTCC TAGCACTCAG CTTCCATGTT 
CTCTGGCTCA TAGGGGACCG AGACACGGAT GTCGGGGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC41A1 ( NM_173854.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_776253.3 Homo sapiens solute carrier family 41 member 1 (SLC41A1), mRNA.

Price & Availability↑

CloneID	OHu15881
Clone ID Related Accession (Same CDS sequence)	NM_173854.5 , NM_173854.6 , XM_005245069.2
Accession Version	NM_173854.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	solute carrier family 41 member 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC119673.3, HY148928.1, DA496198.1, BX641054.1, BC136303.1 and BX648979.1. On Nov 22, 2018 this sequence version replaced NM_173854.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.234119.1, BX648979.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367137.4/ ENSP00000356105.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCTCTA AGCCAGAGCC GAAGGACGTC CACCAACTGA ACGGGACTGG CCCTTCTGCC 
TCTCCCTGCT CTTCAGATGG CCCAGGGAGA GAGCCCTTGG CTGGGACCTC AGAGTTCCTG 
GGGCCTGATG GGGCTGGGGT AGAGGTGGTG ATTGAGTCTC GGGCCAACGC CAAGGGGGTT 
CGGGAGGAGG ACGCCCTGCT GGAGAACGGG AGCCAGAGCA ACGAAAGTGA CGACGTCAGC 
ACAGACCGTG GCCCTGCGCC ACCTTCCCCG CTCAAGGAGA CCTCCTTTTC CATCGGGCTG 
CAAGTACTGT TTCCATTCCT CCTGGCAGGC TTTGGGACCG TGGCTGCTGG CATGGTGTTG 
GACATCGTGC AGCACTGGGA AGTCTTCCAG AAGGTGACAG AGGTCTTCAT CCTAGTGCCT 
GCGCTGCTGG GGCTCAAAGG GAACCTGGAA ATGACCCTGG CATCAAGGCT TTCCACTGCA 
GCCAACATTG GACACATGGA CACACCCAAG GAGCTCTGGC GGATGATCAC TGGGAACATG 
GCCCTCATCC AGGTGCAGGC CACGGTGGTG GGCTTCCTGG CGTCCATCGC AGCCGTCGTC 
TTTGGCTGGA TCCCTGATGG CCACTTCAGT ATTCCGCACG CCTTCCTGCT CTGTGCTAGC 
AGCGTGGCCA CAGCCTTCAT TGCCTCCCTG GTACTGGGTA TGATCATGAT TGGAGTCATC 
ATTGGCTCTC GCAAGATTGG GATCAACCCA GACAACGTGG CCACACCCAT TGCTGCCAGC 
CTGGGCGACC TCATCACCTT GGCGCTGCTC TCAGGCATCA GCTGGGGACT CTACCTGGAA 
CTGAATCACT GGCGATACAT CTACCCACTG GTGTGTGCTT TCTTTGTGGC CCTGCTGCCT 
GTCTGGGTGG TGCTGGCCCG ACGAAGTCCA GCCACAAGGG AGGTGTTGTA CTCGGGCTGG 
GAGCCTGTTA TCATTGCCAT GGCCATCAGC AGTGTGGGAG GCCTCATCTT GGACAAGACT 
GTCTCAGACC CCAACTTTGC TGGGATGGCT GTCTTCACGC CTGTGATTAA TGGTGTTGGG 
GGCAATCTGG TGGCAGTGCA GGCCAGCCGC ATCTCCACCT TCCTGCACAT GAATGGAATG 
CCCGGAGAGA ACTCTGAGCA AGCTCCTCGC CGCTGTCCCA GTCCTTGTAC CACCTTCTTC 
AGCCCTGATG TGAATTCTCG CTCAGCCCGG GTCCTCTTCC TCCTCGTGGT CCCAGGACAC 
CTGGTGTTCC TCTACACCAT CAGCTGTATG CAGGGCGGGC ACACCACCCT CACACTCATC 
TTCATCATCT TCTATATGAC AGCTGCACTG CTCCAGGTGC TGATTCTCCT GTACATCGCA 
GACTGGATGG TGCACTGGAT GTGGGGCCGG GGCCTGGACC CGGACAACTT CTCCATCCCA 
TACTTGACTG CTCTGGGGGA CCTGCTTGGC ACTGGGCTCC TAGCACTCAG CTTCCATGTT 
CTCTGGCTCA TAGGGGACCG AGACACGGAT GTCGGGGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776253.3
CDS	1038..2579
Translation	MSSKPEPKDVHQLNGTGPSASPCSSDGPGREPLAGTSEFLGPDGAGVEVVIESRANAKGVREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELNHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQAPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD

Target ORF information:

RefSeq Version	NM_173854.6
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 41 member 1 (SLC41A1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173854.6

ORF Insert Sequence:

ATGTCCTCTA AGCCAGAGCC GAAGGACGTC CACCAACTGA ACGGGACTGG CCCTTCTGCC 
TCTCCCTGCT CTTCAGATGG CCCAGGGAGA GAGCCCTTGG CTGGGACCTC AGAGTTCCTG 
GGGCCTGATG GGGCTGGGGT AGAGGTGGTG ATTGAGTCTC GGGCCAACGC CAAGGGGGTT 
CGGGAGGAGG ACGCCCTGCT GGAGAACGGG AGCCAGAGCA ACGAAAGTGA CGACGTCAGC 
ACAGACCGTG GCCCTGCGCC ACCTTCCCCG CTCAAGGAGA CCTCCTTTTC CATCGGGCTG 
CAAGTACTGT TTCCATTCCT CCTGGCAGGC TTTGGGACCG TGGCTGCTGG CATGGTGTTG 
GACATCGTGC AGCACTGGGA AGTCTTCCAG AAGGTGACAG AGGTCTTCAT CCTAGTGCCT 
GCGCTGCTGG GGCTCAAAGG GAACCTGGAA ATGACCCTGG CATCAAGGCT TTCCACTGCA 
GCCAACATTG GACACATGGA CACACCCAAG GAGCTCTGGC GGATGATCAC TGGGAACATG 
GCCCTCATCC AGGTGCAGGC CACGGTGGTG GGCTTCCTGG CGTCCATCGC AGCCGTCGTC 
TTTGGCTGGA TCCCTGATGG CCACTTCAGT ATTCCGCACG CCTTCCTGCT CTGTGCTAGC 
AGCGTGGCCA CAGCCTTCAT TGCCTCCCTG GTACTGGGTA TGATCATGAT TGGAGTCATC 
ATTGGCTCTC GCAAGATTGG GATCAACCCA GACAACGTGG CCACACCCAT TGCTGCCAGC 
CTGGGCGACC TCATCACCTT GGCGCTGCTC TCAGGCATCA GCTGGGGACT CTACCTGGAA 
CTGAATCACT GGCGATACAT CTACCCACTG GTGTGTGCTT TCTTTGTGGC CCTGCTGCCT 
GTCTGGGTGG TGCTGGCCCG ACGAAGTCCA GCCACAAGGG AGGTGTTGTA CTCGGGCTGG 
GAGCCTGTTA TCATTGCCAT GGCCATCAGC AGTGTGGGAG GCCTCATCTT GGACAAGACT 
GTCTCAGACC CCAACTTTGC TGGGATGGCT GTCTTCACGC CTGTGATTAA TGGTGTTGGG 
GGCAATCTGG TGGCAGTGCA GGCCAGCCGC ATCTCCACCT TCCTGCACAT GAATGGAATG 
CCCGGAGAGA ACTCTGAGCA AGCTCCTCGC CGCTGTCCCA GTCCTTGTAC CACCTTCTTC 
AGCCCTGATG TGAATTCTCG CTCAGCCCGG GTCCTCTTCC TCCTCGTGGT CCCAGGACAC 
CTGGTGTTCC TCTACACCAT CAGCTGTATG CAGGGCGGGC ACACCACCCT CACACTCATC 
TTCATCATCT TCTATATGAC AGCTGCACTG CTCCAGGTGC TGATTCTCCT GTACATCGCA 
GACTGGATGG TGCACTGGAT GTGGGGCCGG GGCCTGGACC CGGACAACTT CTCCATCCCA 
TACTTGACTG CTCTGGGGGA CCTGCTTGGC ACTGGGCTCC TAGCACTCAG CTTCCATGTT 
CTCTGGCTCA TAGGGGACCG AGACACGGAT GTCGGGGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC41A1 ( XM_005245069.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245126.1 Homo sapiens solute carrier family 41 member 1 (SLC41A1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu15881
Clone ID Related Accession (Same CDS sequence)	NM_173854.5 , NM_173854.6 , XM_005245069.2
Accession Version	XM_005245069.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	solute carrier family 41 member 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005245069.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCTCTA AGCCAGAGCC GAAGGACGTC CACCAACTGA ACGGGACTGG CCCTTCTGCC 
TCTCCCTGCT CTTCAGATGG CCCAGGGAGA GAGCCCTTGG CTGGGACCTC AGAGTTCCTG 
GGGCCTGATG GGGCTGGGGT AGAGGTGGTG ATTGAGTCTC GGGCCAACGC CAAGGGGGTT 
CGGGAGGAGG ACGCCCTGCT GGAGAACGGG AGCCAGAGCA ACGAAAGTGA CGACGTCAGC 
ACAGACCGTG GCCCTGCGCC ACCTTCCCCG CTCAAGGAGA CCTCCTTTTC CATCGGGCTG 
CAAGTACTGT TTCCATTCCT CCTGGCAGGC TTTGGGACCG TGGCTGCTGG CATGGTGTTG 
GACATCGTGC AGCACTGGGA AGTCTTCCAG AAGGTGACAG AGGTCTTCAT CCTAGTGCCT 
GCGCTGCTGG GGCTCAAAGG GAACCTGGAA ATGACCCTGG CATCAAGGCT TTCCACTGCA 
GCCAACATTG GACACATGGA CACACCCAAG GAGCTCTGGC GGATGATCAC TGGGAACATG 
GCCCTCATCC AGGTGCAGGC CACGGTGGTG GGCTTCCTGG CGTCCATCGC AGCCGTCGTC 
TTTGGCTGGA TCCCTGATGG CCACTTCAGT ATTCCGCACG CCTTCCTGCT CTGTGCTAGC 
AGCGTGGCCA CAGCCTTCAT TGCCTCCCTG GTACTGGGTA TGATCATGAT TGGAGTCATC 
ATTGGCTCTC GCAAGATTGG GATCAACCCA GACAACGTGG CCACACCCAT TGCTGCCAGC 
CTGGGCGACC TCATCACCTT GGCGCTGCTC TCAGGCATCA GCTGGGGACT CTACCTGGAA 
CTGAATCACT GGCGATACAT CTACCCACTG GTGTGTGCTT TCTTTGTGGC CCTGCTGCCT 
GTCTGGGTGG TGCTGGCCCG ACGAAGTCCA GCCACAAGGG AGGTGTTGTA CTCGGGCTGG 
GAGCCTGTTA TCATTGCCAT GGCCATCAGC AGTGTGGGAG GCCTCATCTT GGACAAGACT 
GTCTCAGACC CCAACTTTGC TGGGATGGCT GTCTTCACGC CTGTGATTAA TGGTGTTGGG 
GGCAATCTGG TGGCAGTGCA GGCCAGCCGC ATCTCCACCT TCCTGCACAT GAATGGAATG 
CCCGGAGAGA ACTCTGAGCA AGCTCCTCGC CGCTGTCCCA GTCCTTGTAC CACCTTCTTC 
AGCCCTGATG TGAATTCTCG CTCAGCCCGG GTCCTCTTCC TCCTCGTGGT CCCAGGACAC 
CTGGTGTTCC TCTACACCAT CAGCTGTATG CAGGGCGGGC ACACCACCCT CACACTCATC 
TTCATCATCT TCTATATGAC AGCTGCACTG CTCCAGGTGC TGATTCTCCT GTACATCGCA 
GACTGGATGG TGCACTGGAT GTGGGGCCGG GGCCTGGACC CGGACAACTT CTCCATCCCA 
TACTTGACTG CTCTGGGGGA CCTGCTTGGC ACTGGGCTCC TAGCACTCAG CTTCCATGTT 
CTCTGGCTCA TAGGGGACCG AGACACGGAT GTCGGGGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245126.1
CDS	712..2253
Translation	MSSKPEPKDVHQLNGTGPSASPCSSDGPGREPLAGTSEFLGPDGAGVEVVIESRANAKGVREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELNHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQAPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD

Target ORF information:

RefSeq Version	XM_005245069.2
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 41 member 1 (SLC41A1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245069.2

ORF Insert Sequence:

ATGTCCTCTA AGCCAGAGCC GAAGGACGTC CACCAACTGA ACGGGACTGG CCCTTCTGCC 
TCTCCCTGCT CTTCAGATGG CCCAGGGAGA GAGCCCTTGG CTGGGACCTC AGAGTTCCTG 
GGGCCTGATG GGGCTGGGGT AGAGGTGGTG ATTGAGTCTC GGGCCAACGC CAAGGGGGTT 
CGGGAGGAGG ACGCCCTGCT GGAGAACGGG AGCCAGAGCA ACGAAAGTGA CGACGTCAGC 
ACAGACCGTG GCCCTGCGCC ACCTTCCCCG CTCAAGGAGA CCTCCTTTTC CATCGGGCTG 
CAAGTACTGT TTCCATTCCT CCTGGCAGGC TTTGGGACCG TGGCTGCTGG CATGGTGTTG 
GACATCGTGC AGCACTGGGA AGTCTTCCAG AAGGTGACAG AGGTCTTCAT CCTAGTGCCT 
GCGCTGCTGG GGCTCAAAGG GAACCTGGAA ATGACCCTGG CATCAAGGCT TTCCACTGCA 
GCCAACATTG GACACATGGA CACACCCAAG GAGCTCTGGC GGATGATCAC TGGGAACATG 
GCCCTCATCC AGGTGCAGGC CACGGTGGTG GGCTTCCTGG CGTCCATCGC AGCCGTCGTC 
TTTGGCTGGA TCCCTGATGG CCACTTCAGT ATTCCGCACG CCTTCCTGCT CTGTGCTAGC 
AGCGTGGCCA CAGCCTTCAT TGCCTCCCTG GTACTGGGTA TGATCATGAT TGGAGTCATC 
ATTGGCTCTC GCAAGATTGG GATCAACCCA GACAACGTGG CCACACCCAT TGCTGCCAGC 
CTGGGCGACC TCATCACCTT GGCGCTGCTC TCAGGCATCA GCTGGGGACT CTACCTGGAA 
CTGAATCACT GGCGATACAT CTACCCACTG GTGTGTGCTT TCTTTGTGGC CCTGCTGCCT 
GTCTGGGTGG TGCTGGCCCG ACGAAGTCCA GCCACAAGGG AGGTGTTGTA CTCGGGCTGG 
GAGCCTGTTA TCATTGCCAT GGCCATCAGC AGTGTGGGAG GCCTCATCTT GGACAAGACT 
GTCTCAGACC CCAACTTTGC TGGGATGGCT GTCTTCACGC CTGTGATTAA TGGTGTTGGG 
GGCAATCTGG TGGCAGTGCA GGCCAGCCGC ATCTCCACCT TCCTGCACAT GAATGGAATG 
CCCGGAGAGA ACTCTGAGCA AGCTCCTCGC CGCTGTCCCA GTCCTTGTAC CACCTTCTTC 
AGCCCTGATG TGAATTCTCG CTCAGCCCGG GTCCTCTTCC TCCTCGTGGT CCCAGGACAC 
CTGGTGTTCC TCTACACCAT CAGCTGTATG CAGGGCGGGC ACACCACCCT CACACTCATC 
TTCATCATCT TCTATATGAC AGCTGCACTG CTCCAGGTGC TGATTCTCCT GTACATCGCA 
GACTGGATGG TGCACTGGAT GTGGGGCCGG GGCCTGGACC CGGACAACTT CTCCATCCCA 
TACTTGACTG CTCTGGGGGA CCTGCTTGGC ACTGGGCTCC TAGCACTCAG CTTCCATGTT 
CTCTGGCTCA TAGGGGACCG AGACACGGAT GTCGGGGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Knockdown of SLC41A1 magnesium transporter promotes mineralization and attenuates magnesium inhibition during osteogenesis of mesenchymal stromal cells.
Stem cell research & therapy8(1)39(2017 02)
Tsao YT,Shih YY,Liu YA,Liu YS,Lee OK

Genetic Analysis of the ZNF512B, SLC41A1, and ALDH2 Polymorphisms in Parkinson's Disease in the Iranian Population.
Genetic testing and molecular biomarkers20(10)629-632(2016 Oct)
Madadi F,Khaniani MS,Shandiz EE,Ayromlou H,Najmi S,Emamalizadeh B,Taghavi S,Jamshidi J,Tafakhori A,Shahidi GA,Darvish H

Genetic analysis of SLC41A1 in Chinese Parkinson's disease patients.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics168(8)706-11(2015 Dec)
Wang L,Cheng L,Li NN,Yu WJ,Sun XY,Peng R

Insulin Modulates the Na+/Mg2+ Exchanger SLC41A1 and Influences Mg2+ Efflux from Intracellular Stores in Transgenic HEK293 Cells.
The Journal of nutrition145(11)2440-7(2015 Nov)
Mastrototaro L,Tietjen U,Sponder G,Vormann J,Aschenbach JR,Kolisek M

Genetic variants at 1q32.1, 10q11.2 and 19q13.41 are associated with prostate-specific antigen for prostate cancer screening in two Korean population-based cohort studies.
Gene556(2)199-205(2015 Feb)
Kim S,Shin C,Jee SH