TRAPPC6B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TRAPPC6B
Entrez Gene ID	122553
Full Name	trafficking protein particle complex 6B
Synonyms	TPC6
General protein information	Preferred Names trafficking protein particle complex 6B Names trafficking protein particle complex subunit 6B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q21.1
Summary	TRAPPC6B is a component of TRAPP complexes, which are tethering complexes involved in vesicle transport (Kummel et al., 2005 [PubMed 16025134]).[supplied by OMIM, Mar 2008].
Disorder MIM:	610397

mRNA and Protein(s)

mRNA	Protein	Name
XM_017020964.1	XP_016876453.1	trafficking protein particle complex subunit 6B isoform X1
NM_177452.4	NP_803235.1	trafficking protein particle complex subunit 6B isoform 2
XM_017020964.2	XP_016876453.1	trafficking protein particle complex subunit 6B isoform X1
NM_177452.3	NP_803235.1	trafficking protein particle complex subunit 6B isoform 2
NM_001079537.2	NP_001073005.1	trafficking protein particle complex subunit 6B isoform 1
XM_011536409.2	XP_011534711.1	trafficking protein particle complex subunit 6B isoform X2
NM_001079537.1	NP_001073005.1	trafficking protein particle complex subunit 6B isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TRAPPC6B	NP_001073005.1
	TRAPPC6B	XP_001092941.1
Canis lupus familiaris (dog)	TRAPPC6B	XP_537419.1
Gallus gallus (chicken)	TRAPPC6B	NP_001239089.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002385	XP_312570.2
Magnaporthe oryzae (rice blast fungus)	MGG_08836	XP_003713855.1
Oryza sativa (rice)	Os07g0291100	NP_001059395.1
Mus musculus (house mouse)	Trappc6b	NP_084333.1
Danio rerio (zebrafish)	trappc6b	NP_001006029.1
Schizosaccharomyces pombe (fission yeast)	trs33	NP_592831.2
Arabidopsis thaliana (thale cress)	AT3G05000	NP_187151.1
Bos taurus (cattle)	TRAPPC6B	NP_001033223.1
Rattus norvegicus (Norway rat)	Trappc6b	NP_001100203.1
Caenorhabditis elegans (roundworm)	CELE_K08H10.9	NP_505571.1
Neurospora crassa	NCU06212	XP_962928.2
Oryza sativa (rice)	Os09g0244900	NP_001062657.2
Xenopus tropicalis (tropical clawed frog)	trappc6b	XP_002933768.1
Pan troglodytes (chimpanzee)	TRAPPC6B	XP_509918.2
Drosophila melanogaster (fruit fly)	CG6196	NP_650450.1

Gene Ontology
Bibliography

Related articles in PubMed

A homozygous founder mutation in
Marin-Valencia I, Novarino G, Johansen A, Rosti B, Issa MY, Musaev D, Bhat G, Scott E, Silhavy JL, Stanley V, Rosti RO, Gleeson JW, Imam FB, Zaki MS, Gleeson JG
Journal of medical genetics55(1)48-54(2018 Jan)

A TRAPPC6B splicing variant associates to restless legs syndrome.
Aridon P, De Fusco M, Winkelmann JW, Zucconi M, Arnao V, Ferini-Strambi L, Casari G
Parkinsonism & related disorders31135-138(2016 Oct)

Distinct isocomplexes of the TRAPP trafficking factor coexist inside human cells.
K?mmel D, Oeckinghaus A, Wang C, Krappmann D, Heinemann U
FEBS letters582(27)3729-33(2008 Nov)

A mouse TRAPP-related protein is involved in pigmentation.
Gwynn B, Smith RS, Rowe LB, Taylor BA, Peters LL
Genomics88(2)196-203(2006 Aug)

Unique self-palmitoylation activity of the transport protein particle component Bet3: a mechanism required for protein stability.
K?mmel D, Heinemann U, Veit M
Proceedings of the National Academy of Sciences of the United States of America103(34)12701-6(2006 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TRAPPC6B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRAPPC6B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05363	NM_001079537.2 Latest version!	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu30199	NM_177452.4 Latest version!	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu75206	XM_011536409.2 Latest version!	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu84762	XM_017020964.2 Latest version!	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu84762	XM_017020964.1	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu30199	NM_177452.3	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu05363	NM_001079537.1	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TRAPPC6B ( NM_001079537.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073005.1 Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05363
Clone ID Related Accession (Same CDS sequence)	NM_001079537.2 , NM_001079537.1
Accession Version	NM_001079537.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	trafficking protein particle complex subunit 6B isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL132639.4, BX161510.1 and AK025437.1. On Nov 22, 2018 this sequence version replaced NM_001079537.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). CCDS Note: This CCDS ID represents the longer isoform encoded by the TRAPPC6B gene. The shorter isoform is represented by CCDS9670.1. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.259889.1, SRR1660805.28761.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142670, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000330149.10/ ENSP00000330289.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGGGC ATCTATGTAC TTCAGGACAA CAAATTTCGC 
CTGCTTACTC AGATGTCTGC AGGAAAACAG TATTTAGAAC ATGCATCTAA GTATTTAGCA 
TTTACGTGTG GCTTAATCAG AGGTGGCTTA TCAAACTTGG GAATAAAAAG TATTGTAACA 
GCTGAAGTGT CTTCAATGCC TGCTTGCAAA TTTCAGGTGA TGATACAGAA GCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073005.1
CDS	239..715
Translation	MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL

Target ORF information:

RefSeq Version	NM_001079537.2
Organism	Homo sapiens(human)
Definition	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001079537.2

ORF Insert Sequence:

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGGGC ATCTATGTAC TTCAGGACAA CAAATTTCGC 
CTGCTTACTC AGATGTCTGC AGGAAAACAG TATTTAGAAC ATGCATCTAA GTATTTAGCA 
TTTACGTGTG GCTTAATCAG AGGTGGCTTA TCAAACTTGG GAATAAAAAG TATTGTAACA 
GCTGAAGTGT CTTCAATGCC TGCTTGCAAA TTTCAGGTGA TGATACAGAA GCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRAPPC6B ( NM_001079537.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073005.1 Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05363
Clone ID Related Accession (Same CDS sequence)	NM_001079537.2 , NM_001079537.1
Accession Version	NM_001079537.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	trafficking protein particle complex subunit 6B isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL132639.4, BX161510.1 and AK025437.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). CCDS Note: This CCDS ID represents the longer isoform encoded by the TRAPPC6B gene. The shorter isoform is represented by CCDS9670.1. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.168495.1, SRR1803614.228442.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142670, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGGGC ATCTATGTAC TTCAGGACAA CAAATTTCGC 
CTGCTTACTC AGATGTCTGC AGGAAAACAG TATTTAGAAC ATGCATCTAA GTATTTAGCA 
TTTACGTGTG GCTTAATCAG AGGTGGCTTA TCAAACTTGG GAATAAAAAG TATTGTAACA 
GCTGAAGTGT CTTCAATGCC TGCTTGCAAA TTTCAGGTGA TGATACAGAA GCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073005.1
CDS	336..812
Translation	MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL

Target ORF information:

RefSeq Version	NM_001079537.1
Organism	Homo sapiens(human)
Definition	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001079537.1

ORF Insert Sequence:

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGGGC ATCTATGTAC TTCAGGACAA CAAATTTCGC 
CTGCTTACTC AGATGTCTGC AGGAAAACAG TATTTAGAAC ATGCATCTAA GTATTTAGCA 
TTTACGTGTG GCTTAATCAG AGGTGGCTTA TCAAACTTGG GAATAAAAAG TATTGTAACA 
GCTGAAGTGT CTTCAATGCC TGCTTGCAAA TTTCAGGTGA TGATACAGAA GCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRAPPC6B ( NM_177452.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_803235.1 Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30199
Clone ID Related Accession (Same CDS sequence)	NM_177452.4 , NM_177452.3
Accession Version	NM_177452.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	trafficking protein particle complex subunit 6B isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL132639.4 and BC047328.1. On May 31, 2019 this sequence version replaced NM_177452.3. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the mid-coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. CCDS Note: This CCDS ID represents the shorter isoform encoded by the TRAPPC6B gene. Although this protein lacks a segment of the predicted TRAPP_Bet3 domain compared to the longer isoform (represented by CCDS41947.1), there are several transcripts supporting this shorter variant, and there is no experimental evidence indicating that this variant does not encode a protein. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.110804.1, SRR1803617.251021.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467147, SAMN03267776 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGTAT TTAGCATTTA CGTGTGGCTT AATCAGAGGT 
GGCTTATCAA ACTTGGGAAT AAAAAGTATT GTAACAGCTG AAGTGTCTTC AATGCCTGCT 
TGCAAATTTC AGGTGATGAT ACAGAAGCTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_803235.1
CDS	239..631
Translation	MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL

Target ORF information:

RefSeq Version	NM_177452.4
Organism	Homo sapiens(human)
Definition	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177452.4

ORF Insert Sequence:

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGTAT TTAGCATTTA CGTGTGGCTT AATCAGAGGT 
GGCTTATCAA ACTTGGGAAT AAAAAGTATT GTAACAGCTG AAGTGTCTTC AATGCCTGCT 
TGCAAATTTC AGGTGATGAT ACAGAAGCTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRAPPC6B ( NM_177452.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_803235.1 Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30199
Clone ID Related Accession (Same CDS sequence)	NM_177452.4 , NM_177452.3
Accession Version	NM_177452.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-10-20
Organism	Homo sapiens(human)
Product	trafficking protein particle complex subunit 6B isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL132639.4 and BC047328.1. On Dec 2, 2006 this sequence version replaced NM_177452.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the mid-coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. CCDS Note: This CCDS ID represents the shorter isoform encoded by the TRAPPC6B gene. Although this protein lacks a segment of the predicted TRAPP_Bet3 domain compared to the longer isoform (represented by CCDS41947.1), there are several transcripts supporting this shorter variant, and there is no experimental evidence indicating that this variant does not encode a protein. ##Evidence-Data-START## Transcript exon combination :: BC047328.1, AK056690.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467147, SAMN03267776 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGTAT TTAGCATTTA CGTGTGGCTT AATCAGAGGT 
GGCTTATCAA ACTTGGGAAT AAAAAGTATT GTAACAGCTG AAGTGTCTTC AATGCCTGCT 
TGCAAATTTC AGGTGATGAT ACAGAAGCTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_803235.1
CDS	336..728
Translation	MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL

Target ORF information:

RefSeq Version	NM_177452.3
Organism	Homo sapiens(human)
Definition	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177452.3

ORF Insert Sequence:

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGTAT TTAGCATTTA CGTGTGGCTT AATCAGAGGT 
GGCTTATCAA ACTTGGGAAT AAAAAGTATT GTAACAGCTG AAGTGTCTTC AATGCCTGCT 
TGCAAATTTC AGGTGATGAT ACAGAAGCTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRAPPC6B ( XM_011536409.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534711.1 Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu75206
Clone ID Related Accession (Same CDS sequence)	XM_011536409.2
Accession Version	XM_011536409.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	trafficking protein particle complex subunit 6B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011536409.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGTTTC GAGTGGGACA AGGATTGATA GAAAGGTTTA CAAAAGATAC TGCAAGGTTC 
AAGGATGAGT TAGATATCAT GAAGTTCATT TGTAAAGATT TTTGGACTAC GGTATTCAAG 
AAACAAATCG ACAATCTAAG GACAAATCAT CAGGGCATCT ATGTACTTCA GGACAACAAA 
TTTCGCCTGC TTACTCAGAT GTCTGCAGGA AAACAGTATT TAGAACATGC ATCTAAGTAT 
TTAGCATTTA CGTGTGGCTT AATCAGAGGT GGCTTATCAA ACTTGGGAAT AAAAAGTATT 
GTAACAGCTG AAGTGTCTTC AATGCCTGCT TGCAAATTTC AGGTGATGAT ACAGAAGCTG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534711.1
CDS	470..832
Translation	MGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL

Target ORF information:

RefSeq Version	XM_011536409.2
Organism	Homo sapiens(human)
Definition	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011536409.2

ORF Insert Sequence:

ATGGGGTTTC GAGTGGGACA AGGATTGATA GAAAGGTTTA CAAAAGATAC TGCAAGGTTC 
AAGGATGAGT TAGATATCAT GAAGTTCATT TGTAAAGATT TTTGGACTAC GGTATTCAAG 
AAACAAATCG ACAATCTAAG GACAAATCAT CAGGGCATCT ATGTACTTCA GGACAACAAA 
TTTCGCCTGC TTACTCAGAT GTCTGCAGGA AAACAGTATT TAGAACATGC ATCTAAGTAT 
TTAGCATTTA CGTGTGGCTT AATCAGAGGT GGCTTATCAA ACTTGGGAAT AAAAAGTATT 
GTAACAGCTG AAGTGTCTTC AATGCCTGCT TGCAAATTTC AGGTGATGAT ACAGAAGCTG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRAPPC6B ( XM_017020964.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876453.1 Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant X1, mRNA.

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CloneID	OHu84762
Clone ID Related Accession (Same CDS sequence)	XM_017020964.1 , XM_017020964.2
Accession Version	XM_017020964.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	trafficking protein particle complex subunit 6B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGGGC ATCTATGTAC TTCAGGACAA CAAATTTCGC 
CTGCTTACTC AGATGTCTGC AGGAAAACAG TATTTAGAAC ATGCATCTAA GTATTTAGCA 
TTTACGTGTG GCTTAATCAG AGGTGGCTTA TCAAACTTGG GAATAAAAAG TATTGTAACA 
GCTGAAGTGT CTTCAATGCC TGCTTGTAAG TTGAATTCGC CTTTCTTACA AATGTTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876453.1
CDS	309..788
Translation	MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKLNSPFLQMF

Target ORF information:

RefSeq Version	XM_017020964.1
Organism	Homo sapiens(human)
Definition	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017020964.1

ORF Insert Sequence:

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGGGC ATCTATGTAC TTCAGGACAA CAAATTTCGC 
CTGCTTACTC AGATGTCTGC AGGAAAACAG TATTTAGAAC ATGCATCTAA GTATTTAGCA 
TTTACGTGTG GCTTAATCAG AGGTGGCTTA TCAAACTTGG GAATAAAAAG TATTGTAACA 
GCTGAAGTGT CTTCAATGCC TGCTTGTAAG TTGAATTCGC CTTTCTTACA AATGTTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRAPPC6B ( XM_017020964.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876453.1 Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu84762
Clone ID Related Accession (Same CDS sequence)	XM_017020964.1 , XM_017020964.2
Accession Version	XM_017020964.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	trafficking protein particle complex subunit 6B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017020964.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGGGC ATCTATGTAC TTCAGGACAA CAAATTTCGC 
CTGCTTACTC AGATGTCTGC AGGAAAACAG TATTTAGAAC ATGCATCTAA GTATTTAGCA 
TTTACGTGTG GCTTAATCAG AGGTGGCTTA TCAAACTTGG GAATAAAAAG TATTGTAACA 
GCTGAAGTGT CTTCAATGCC TGCTTGTAAG TTGAATTCGC CTTTCTTACA AATGTTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876453.1
CDS	306..785
Translation	MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKLNSPFLQMF

Target ORF information:

RefSeq Version	XM_017020964.2
Organism	Homo sapiens(human)
Definition	Homo sapiens trafficking protein particle complex 6B (TRAPPC6B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017020964.2

ORF Insert Sequence:

ATGGCGGATG AGGCGTTGTT TTTGCTTCTC CATAACGAGA TGGTGTCTGG AGTGTACAAG 
TCCGCGGAGC AGGGGGAGGT GGAAAACGGA CGATGTATTA CTAAGCTGGA AAACATGGGG 
TTTCGAGTGG GACAAGGATT GATAGAAAGG TTTACAAAAG ATACTGCAAG GTTCAAGGAT 
GAGTTAGATA TCATGAAGTT CATTTGTAAA GATTTTTGGA CTACGGTATT CAAGAAACAA 
ATCGACAATC TAAGGACAAA TCATCAGGGC ATCTATGTAC TTCAGGACAA CAAATTTCGC 
CTGCTTACTC AGATGTCTGC AGGAAAACAG TATTTAGAAC ATGCATCTAA GTATTTAGCA 
TTTACGTGTG GCTTAATCAG AGGTGGCTTA TCAAACTTGG GAATAAAAAG TATTGTAACA 
GCTGAAGTGT CTTCAATGCC TGCTTGTAAG TTGAATTCGC CTTTCTTACA AATGTTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A homozygous founder mutation in
Journal of medical genetics55(1)48-54(2018 Jan)
Marin-Valencia I,Novarino G,Johansen A,Rosti B,Issa MY,Musaev D,Bhat G,Scott E,Silhavy JL,Stanley V,Rosti RO,Gleeson JW,Imam FB,Zaki MS,Gleeson JG

A TRAPPC6B splicing variant associates to restless legs syndrome.
Parkinsonism & related disorders31135-138(2016 Oct)
Aridon P,De Fusco M,Winkelmann JW,Zucconi M,Arnao V,Ferini-Strambi L,Casari G

Distinct isocomplexes of the TRAPP trafficking factor coexist inside human cells.
FEBS letters582(27)3729-33(2008 Nov)
K?mmel D,Oeckinghaus A,Wang C,Krappmann D,Heinemann U

A mouse TRAPP-related protein is involved in pigmentation.
Genomics88(2)196-203(2006 Aug)
Gwynn B,Smith RS,Rowe LB,Taylor BA,Peters LL

Unique self-palmitoylation activity of the transport protein particle component Bet3: a mechanism required for protein stability.
Proceedings of the National Academy of Sciences of the United States of America103(34)12701-6(2006 Aug)
K?mmel D,Heinemann U,Veit M

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TRAPPC6B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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