MXD4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MXD4
Entrez Gene ID	10608
Full Name	MAX dimerization protein 4
Synonyms	MAD4,MST149,MSTP149,bHLHc12
General protein information	Preferred Names MAX dimerization protein 4 Names max dimerization protein 4 Mad4 homolog class C basic helix-loop-helix protein 12 max dimerizer 4 max-associated protein 4 max-interacting transcriptional repressor MAD4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4p16.3
Summary	This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_006454.2	NP_006445.1	max dimerization protein 4
XM_011513388.3	XP_011511690.1	max dimerization protein 4 isoform X1
XM_011513388.2	XP_011511690.1	max dimerization protein 4 isoform X1
XM_017007656.2	XP_016863145.1	max dimerization protein 4 isoform X3
XM_017007656.1	XP_016863145.1	max dimerization protein 4 isoform X3
XM_017007655.1	XP_016863144.1	max dimerization protein 4 isoform X2
NM_006454.3	NP_006445.1	max dimerization protein 4

Pathways from BioSystems

Homologies

	LOC722345	XP_001118504.2
Danio rerio (zebrafish)	mxd4	XP_687970.6
Canis lupus familiaris (dog)	MXD4	XP_003639025.1
Mus musculus (house mouse)	Mxd4	NP_034883.2
Gallus gallus (chicken)	MXD4	NP_001006460.1
Homo sapiens (human)	MXD4	NP_006445.1
Bos taurus (cattle)	MXD4	NP_001069724.1
Pan troglodytes (chimpanzee)	MXD4	XP_517071.3
Xenopus tropicalis (tropical clawed frog)	mxd4	NP_001096239.1

Gene Ontology
Bibliography

Related articles in PubMed

Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells.
Yang W, Yang X, David G, Dorsey JF
Cancer biology & therapy13(13)1339-48(2012 Nov)

Toward an understanding of the protein interaction network of the human liver.
Wang J, Huo K, Ma L, Tang L, Li D, Huang X, Yuan Y, Li C, Wang W, Guan W, Chen H, Jin C, Wei J, Zhang W, Yang Y, Liu Q, Zhou Y, Zhang C, Wu Z, Xu W, Zhang Y, Liu T, Yu D, Zhang Y, Chen L, Zhu D, Zhong X, Kang L, Gan X, Yu X, Ma Q, Yan J, Zhou L, Liu Z, Zhu Y, Zhou T, He F, Yang X
Molecular systems biology7536(2011 Oct)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts.
Marcotte R, Chen JM, Huard S, Wang E
Journal of cellular biochemistry96(5)1071-85(2005 Dec)

Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin.
Pope SN, Lee IR
The Journal of steroid biochemistry and molecular biology94(1-3)203-8(2005 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The E3 ligase activity of c-IAP1 was not required for downregulation of Mad4 expression.
Title: Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells.

replicative senescence-specific factors may block c-Myc inhibition of Miz-1 activation of hMad4 expression, and the continual presence of hMad4 protein may transcriptionally repress selected c-Myc target genes
Title: c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts.

Data suggest that the biological function of the interaction between T-complex protein 10-like and MAD4 may be to maintain the differentiation state in liver cells.
Title: Human liver specific transcriptional factor TCP10L binds to MAD4.

regulation by a transcriptional repressor complex that contains Miz-1 and c-Myc
Title: Mad4 is regulated by a transcriptional repressor complex that contains Miz-1 and c-Myc.

The following MXD4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MXD4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05408	NM_006454.3 Latest version!	Homo sapiens MAX dimerization protein 4 (MXD4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu64182	XM_011513388.3 Latest version!	Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu94854	XM_017007655.1 Latest version!	Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu94855	XM_017007656.2 Latest version!	Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu64182	XM_011513388.2	Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu94855	XM_017007656.1	Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu05408	NM_006454.2	Homo sapiens MAX dimerization protein 4 (MXD4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MXD4 ( NM_006454.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_006445.1 Homo sapiens MAX dimerization protein 4 (MXD4), mRNA.

Price & Availability↑

CloneID	OHu05408
Clone ID Related Accession (Same CDS sequence)	NM_006454.2 , NM_006454.3
Accession Version	NM_006454.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 630bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	max dimerization protein 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF082740.1. On Oct 23, 2000 this sequence version replaced NM_006454.1. ##Evidence-Data-START## Transcript exon combination :: AF082740.1, SRR1660807.215519.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCTGA ACTCCCTGCT GATCCTGCTG GAGGCGGCCG AGTACCTGGA GCGCAGGGAT 
CGAGAGGCCG AGCACGGCTA CGCCTCGGTG CTGCCCTTCG ACGGCGACTT CGCCAGGGAG 
AAAACAAAGG CGGCCGGCCT GGTGCGCAAG GCCCCGAACA ACAGGTCTTC ACACAACGAG 
CTAGAAAAGC ACAGACGAGC CAAACTCAGG CTGTACCTTG AGCAGCTCAA GCAACTGGTG 
CCCCTGGGCC CCGACAGCAC CCGCCACACC ACGCTGAGCC TCCTGAAGCG GGCCAAGGTG 
CACATCAAGA AACTGGAGGA GCAGGACCGC CGGGCACTGA GCATCAAGGA GCAGCTGCAG 
CAGGAGCATC GTTTCCTGAA GCGGCGCCTG GAGCAGCTGT CGGTGCAGAG CGTGGAGCGC 
GTGCGCACAG ATAGCACGGG CTCTGCTGTC TCCACGGACG ACTCAGAGCA AGAAGTGGAC 
ATAGAGGGCA TGGAGTTTGG CCCTGGTGAG CTGGACAGTG TTGGCAGCAG CAGTGACGCG 
GACGACCACT ACAGCCTGCA GAGTGGCACC GGCGGCGACA GTGGCTTCGG GCCCCACTGC 
CGGCGGCTGG GCCGCCCCGC CCTCTCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006445.1
CDS	33..662
Translation	MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSVGSSSDADDHYSLQSGTGGDSGFGPHCRRLGRPALS

Target ORF information:

RefSeq Version	NM_006454.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MAX dimerization protein 4 (MXD4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006454.2

ORF Insert Sequence:

ATGGAGCTGA ACTCCCTGCT GATCCTGCTG GAGGCGGCCG AGTACCTGGA GCGCAGGGAT 
CGAGAGGCCG AGCACGGCTA CGCCTCGGTG CTGCCCTTCG ACGGCGACTT CGCCAGGGAG 
AAAACAAAGG CGGCCGGCCT GGTGCGCAAG GCCCCGAACA ACAGGTCTTC ACACAACGAG 
CTAGAAAAGC ACAGACGAGC CAAACTCAGG CTGTACCTTG AGCAGCTCAA GCAACTGGTG 
CCCCTGGGCC CCGACAGCAC CCGCCACACC ACGCTGAGCC TCCTGAAGCG GGCCAAGGTG 
CACATCAAGA AACTGGAGGA GCAGGACCGC CGGGCACTGA GCATCAAGGA GCAGCTGCAG 
CAGGAGCATC GTTTCCTGAA GCGGCGCCTG GAGCAGCTGT CGGTGCAGAG CGTGGAGCGC 
GTGCGCACAG ATAGCACGGG CTCTGCTGTC TCCACGGACG ACTCAGAGCA AGAAGTGGAC 
ATAGAGGGCA TGGAGTTTGG CCCTGGTGAG CTGGACAGTG TTGGCAGCAG CAGTGACGCG 
GACGACCACT ACAGCCTGCA GAGTGGCACC GGCGGCGACA GTGGCTTCGG GCCCCACTGC 
CGGCGGCTGG GCCGCCCCGC CCTCTCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MXD4 ( NM_006454.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006445.1 Homo sapiens MAX dimerization protein 4 (MXD4), mRNA.

Price & Availability↑

CloneID	OHu05408
Clone ID Related Accession (Same CDS sequence)	NM_006454.2 , NM_006454.3
Accession Version	NM_006454.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 630bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	max dimerization protein 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL158068.18. On May 17, 2019 this sequence version replaced NM_006454.2. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.215519.1, AF082740.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000337190.7/ ENSP00000337889.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCTGA ACTCCCTGCT GATCCTGCTG GAGGCGGCCG AGTACCTGGA GCGCAGGGAT 
CGAGAGGCCG AGCACGGCTA CGCCTCGGTG CTGCCCTTCG ACGGCGACTT CGCCAGGGAG 
AAAACAAAGG CGGCCGGCCT GGTGCGCAAG GCCCCGAACA ACAGGTCTTC ACACAACGAG 
CTAGAAAAGC ACAGACGAGC CAAACTCAGG CTGTACCTTG AGCAGCTCAA GCAACTGGTG 
CCCCTGGGCC CCGACAGCAC CCGCCACACC ACGCTGAGCC TCCTGAAGCG GGCCAAGGTG 
CACATCAAGA AACTGGAGGA GCAGGACCGC CGGGCACTGA GCATCAAGGA GCAGCTGCAG 
CAGGAGCATC GTTTCCTGAA GCGGCGCCTG GAGCAGCTGT CGGTGCAGAG CGTGGAGCGC 
GTGCGCACAG ATAGCACGGG CTCTGCTGTC TCCACGGACG ACTCAGAGCA AGAAGTGGAC 
ATAGAGGGCA TGGAGTTTGG CCCTGGTGAG CTGGACAGTG TTGGCAGCAG CAGTGACGCG 
GACGACCACT ACAGCCTGCA GAGTGGCACC GGCGGCGACA GTGGCTTCGG GCCCCACTGC 
CGGCGGCTGG GCCGCCCCGC CCTCTCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006445.1
CDS	130..759
Translation	MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSVGSSSDADDHYSLQSGTGGDSGFGPHCRRLGRPALS

Target ORF information:

RefSeq Version	NM_006454.3
Organism	Homo sapiens(human)
Definition	Homo sapiens MAX dimerization protein 4 (MXD4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006454.3

ORF Insert Sequence:

ATGGAGCTGA ACTCCCTGCT GATCCTGCTG GAGGCGGCCG AGTACCTGGA GCGCAGGGAT 
CGAGAGGCCG AGCACGGCTA CGCCTCGGTG CTGCCCTTCG ACGGCGACTT CGCCAGGGAG 
AAAACAAAGG CGGCCGGCCT GGTGCGCAAG GCCCCGAACA ACAGGTCTTC ACACAACGAG 
CTAGAAAAGC ACAGACGAGC CAAACTCAGG CTGTACCTTG AGCAGCTCAA GCAACTGGTG 
CCCCTGGGCC CCGACAGCAC CCGCCACACC ACGCTGAGCC TCCTGAAGCG GGCCAAGGTG 
CACATCAAGA AACTGGAGGA GCAGGACCGC CGGGCACTGA GCATCAAGGA GCAGCTGCAG 
CAGGAGCATC GTTTCCTGAA GCGGCGCCTG GAGCAGCTGT CGGTGCAGAG CGTGGAGCGC 
GTGCGCACAG ATAGCACGGG CTCTGCTGTC TCCACGGACG ACTCAGAGCA AGAAGTGGAC 
ATAGAGGGCA TGGAGTTTGG CCCTGGTGAG CTGGACAGTG TTGGCAGCAG CAGTGACGCG 
GACGACCACT ACAGCCTGCA GAGTGGCACC GGCGGCGACA GTGGCTTCGG GCCCCACTGC 
CGGCGGCTGG GCCGCCCCGC CCTCTCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MXD4 ( XM_011513388.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511690.1 Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu64182
Clone ID Related Accession (Same CDS sequence)	XM_011513388.3 , XM_011513388.2
Accession Version	XM_011513388.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	max dimerization protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011513388.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCTGCC AAGCGGCATC CTGGGAGGCC CGGGAGCCCT GGCTGGCCTG TGGGGTCCTG 
CCTGGACACG GAAGGTGGCC TGGAGCTGGG AGCGAGGTCC CCCTGCCTCG TTATCCTCCA 
GGCAGATGCT GTGGCACACC CTGTGGTGCT GGGAATTGTG TGCCCGCGTC TGAATGGGCA 
AGACAGGTCT TCACACAACG AGCTAGAAAA GCACAGAGAC CGCATCCCAG GCACTCAGAG 
GCTGAGCCAC ATCCTCCACT GCTCCCCGCG GGCACTAACA TTGCCGATGA GACTTGGATA 
AGGAGGGGAC CTTGTTCTCC ATTTCCTCAC TTGATCTTTC ACCCGACACC ACGTACACGA 
GCCAAACTCA GGCTGTACCT TGAGCAGCTC AAGCAACTGG TGCCCCTGGG CCCCGACAGC 
ACCCGCCACA CCACGCTGAG CCTCCTGAAG CGGGCCAAGG TGCACATCAA GAAACTGGAG 
GAGCAGGACC GCCGGGCACT GAGCATCAAG GAGCAGCTGC AGCAGGAGCA TCGTTTCCTG 
AAGCGGCGCC TGGAGCAGCT GTCGGTGCAG AGCGTGGAGC GCGTGCGCAC AGATAGCACG 
GGCTCTGCTG TCTCCACGGA CGACTCAGAG CAAGAAGTGG ACATAGAGGG CATGGAGTTT 
GGCCCTGGTG AGCTGGACAG TGTTGGCAGC AGCAGTGACG CGGACGACCA CTACAGCCTG 
CAGAGTGGCA CCGGCGGCGA CAGTGGCTTC GGGCCCCACT GCCGGCGGCT GGGCCGCCCC 
GCCCTCTCGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511690.1
CDS	375..1166
Translation	MLCQAASWEAREPWLACGVLPGHGRWPGAGSEVPLPRYPPGRCCGTPCGAGNCVPASEWARQVFTQRARKAQRPHPRHSEAEPHPPLLPAGTNIADETWIRRGPCSPFPHLIFHPTPRTRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSVGSSSDADDHYSLQSGTGGDSGFGPHCRRLGRPALS

Target ORF information:

RefSeq Version	XM_011513388.3
Organism	Homo sapiens(human)
Definition	Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513388.3

ORF Insert Sequence:

ATGCTCTGCC AAGCGGCATC CTGGGAGGCC CGGGAGCCCT GGCTGGCCTG TGGGGTCCTG 
CCTGGACACG GAAGGTGGCC TGGAGCTGGG AGCGAGGTCC CCCTGCCTCG TTATCCTCCA 
GGCAGATGCT GTGGCACACC CTGTGGTGCT GGGAATTGTG TGCCCGCGTC TGAATGGGCA 
AGACAGGTCT TCACACAACG AGCTAGAAAA GCACAGAGAC CGCATCCCAG GCACTCAGAG 
GCTGAGCCAC ATCCTCCACT GCTCCCCGCG GGCACTAACA TTGCCGATGA GACTTGGATA 
AGGAGGGGAC CTTGTTCTCC ATTTCCTCAC TTGATCTTTC ACCCGACACC ACGTACACGA 
GCCAAACTCA GGCTGTACCT TGAGCAGCTC AAGCAACTGG TGCCCCTGGG CCCCGACAGC 
ACCCGCCACA CCACGCTGAG CCTCCTGAAG CGGGCCAAGG TGCACATCAA GAAACTGGAG 
GAGCAGGACC GCCGGGCACT GAGCATCAAG GAGCAGCTGC AGCAGGAGCA TCGTTTCCTG 
AAGCGGCGCC TGGAGCAGCT GTCGGTGCAG AGCGTGGAGC GCGTGCGCAC AGATAGCACG 
GGCTCTGCTG TCTCCACGGA CGACTCAGAG CAAGAAGTGG ACATAGAGGG CATGGAGTTT 
GGCCCTGGTG AGCTGGACAG TGTTGGCAGC AGCAGTGACG CGGACGACCA CTACAGCCTG 
CAGAGTGGCA CCGGCGGCGA CAGTGGCTTC GGGCCCCACT GCCGGCGGCT GGGCCGCCCC 
GCCCTCTCGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MXD4 ( XM_011513388.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511690.1 Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu64182
Clone ID Related Accession (Same CDS sequence)	XM_011513388.3 , XM_011513388.2
Accession Version	XM_011513388.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	max dimerization protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011513388.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCTGCC AAGCGGCATC CTGGGAGGCC CGGGAGCCCT GGCTGGCCTG TGGGGTCCTG 
CCTGGACACG GAAGGTGGCC TGGAGCTGGG AGCGAGGTCC CCCTGCCTCG TTATCCTCCA 
GGCAGATGCT GTGGCACACC CTGTGGTGCT GGGAATTGTG TGCCCGCGTC TGAATGGGCA 
AGACAGGTCT TCACACAACG AGCTAGAAAA GCACAGAGAC CGCATCCCAG GCACTCAGAG 
GCTGAGCCAC ATCCTCCACT GCTCCCCGCG GGCACTAACA TTGCCGATGA GACTTGGATA 
AGGAGGGGAC CTTGTTCTCC ATTTCCTCAC TTGATCTTTC ACCCGACACC ACGTACACGA 
GCCAAACTCA GGCTGTACCT TGAGCAGCTC AAGCAACTGG TGCCCCTGGG CCCCGACAGC 
ACCCGCCACA CCACGCTGAG CCTCCTGAAG CGGGCCAAGG TGCACATCAA GAAACTGGAG 
GAGCAGGACC GCCGGGCACT GAGCATCAAG GAGCAGCTGC AGCAGGAGCA TCGTTTCCTG 
AAGCGGCGCC TGGAGCAGCT GTCGGTGCAG AGCGTGGAGC GCGTGCGCAC AGATAGCACG 
GGCTCTGCTG TCTCCACGGA CGACTCAGAG CAAGAAGTGG ACATAGAGGG CATGGAGTTT 
GGCCCTGGTG AGCTGGACAG TGTTGGCAGC AGCAGTGACG CGGACGACCA CTACAGCCTG 
CAGAGTGGCA CCGGCGGCGA CAGTGGCTTC GGGCCCCACT GCCGGCGGCT GGGCCGCCCC 
GCCCTCTCGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511690.1
CDS	376..1167
Translation	MLCQAASWEAREPWLACGVLPGHGRWPGAGSEVPLPRYPPGRCCGTPCGAGNCVPASEWARQVFTQRARKAQRPHPRHSEAEPHPPLLPAGTNIADETWIRRGPCSPFPHLIFHPTPRTRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSVGSSSDADDHYSLQSGTGGDSGFGPHCRRLGRPALS

Target ORF information:

RefSeq Version	XM_011513388.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513388.2

ORF Insert Sequence:

ATGCTCTGCC AAGCGGCATC CTGGGAGGCC CGGGAGCCCT GGCTGGCCTG TGGGGTCCTG 
CCTGGACACG GAAGGTGGCC TGGAGCTGGG AGCGAGGTCC CCCTGCCTCG TTATCCTCCA 
GGCAGATGCT GTGGCACACC CTGTGGTGCT GGGAATTGTG TGCCCGCGTC TGAATGGGCA 
AGACAGGTCT TCACACAACG AGCTAGAAAA GCACAGAGAC CGCATCCCAG GCACTCAGAG 
GCTGAGCCAC ATCCTCCACT GCTCCCCGCG GGCACTAACA TTGCCGATGA GACTTGGATA 
AGGAGGGGAC CTTGTTCTCC ATTTCCTCAC TTGATCTTTC ACCCGACACC ACGTACACGA 
GCCAAACTCA GGCTGTACCT TGAGCAGCTC AAGCAACTGG TGCCCCTGGG CCCCGACAGC 
ACCCGCCACA CCACGCTGAG CCTCCTGAAG CGGGCCAAGG TGCACATCAA GAAACTGGAG 
GAGCAGGACC GCCGGGCACT GAGCATCAAG GAGCAGCTGC AGCAGGAGCA TCGTTTCCTG 
AAGCGGCGCC TGGAGCAGCT GTCGGTGCAG AGCGTGGAGC GCGTGCGCAC AGATAGCACG 
GGCTCTGCTG TCTCCACGGA CGACTCAGAG CAAGAAGTGG ACATAGAGGG CATGGAGTTT 
GGCCCTGGTG AGCTGGACAG TGTTGGCAGC AGCAGTGACG CGGACGACCA CTACAGCCTG 
CAGAGTGGCA CCGGCGGCGA CAGTGGCTTC GGGCCCCACT GCCGGCGGCT GGGCCGCCCC 
GCCCTCTCGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MXD4 ( XM_017007655.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863144.1 Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu94854
Clone ID Related Accession (Same CDS sequence)	XM_017007655.1
Accession Version	XM_017007655.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	max dimerization protein 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTGA ACTCCCTGCT GATCCTGCTG GAGGCGGCCG AGTACCTGGA GCGCAGGGAT 
CGAGAGGCCG AGCACGGCTA CGCCTCGGTG CTGCCCTTCG ACGGCGACTT CGCCAGGGAG 
AAAACAAAGG CGGCCGGCCT GGTGCGCAAG GCCCCGAACA ACAGGTCTTC ACACAACGAG 
CTAGAAAAGC ACAGGTGTTC CGTGATTTCT AAAGCGGTCT GTTCACGGAC CTCCCCTGCA 
CCCCACCCCA GAGACCGCAT CCCAGGCACT CAGAGGCTGA GCCACATCCT CCACTGCTCC 
CCGCGGGCAC TAACATTGCC GATGAGACTT GGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863144.1
CDS	160..495
Translation	MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNRSSHNELEKHRCSVISKAVCSRTSPAPHPRDRIPGTQRLSHILHCSPRALTLPMRLG

Target ORF information:

RefSeq Version	XM_017007655.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007655.1

ORF Insert Sequence:

ATGGAGCTGA ACTCCCTGCT GATCCTGCTG GAGGCGGCCG AGTACCTGGA GCGCAGGGAT 
CGAGAGGCCG AGCACGGCTA CGCCTCGGTG CTGCCCTTCG ACGGCGACTT CGCCAGGGAG 
AAAACAAAGG CGGCCGGCCT GGTGCGCAAG GCCCCGAACA ACAGGTCTTC ACACAACGAG 
CTAGAAAAGC ACAGGTGTTC CGTGATTTCT AAAGCGGTCT GTTCACGGAC CTCCCCTGCA 
CCCCACCCCA GAGACCGCAT CCCAGGCACT CAGAGGCTGA GCCACATCCT CCACTGCTCC 
CCGCGGGCAC TAACATTGCC GATGAGACTT GGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MXD4 ( XM_017007656.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863145.1 Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu94855
Clone ID Related Accession (Same CDS sequence)	XM_017007656.2 , XM_017007656.1
Accession Version	XM_017007656.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 324bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	max dimerization protein 4 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017007656.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTGA ACTCCCTGCT GATCCTGCTG GAGGCGGCCG AGTACCTGGA GCGCAGGGAT 
CGAGAGGCCG AGCACGGCTA CGCCTCGGTG CTGCCCTTCG ACGGCGACTT CGCCAGGGAG 
AAAACAAAGG CGGCCGGCCT GGTGCGCAAG GCCCCGAACA ACAGCGGCAT CCTGGGAGGC 
CCGGGAGCCC TGGCTGGCCT GTGGGGTCCT GCCTGGACAC GGAAGGTGGC CTGGAGCTGG 
GAGCGAGGTC CCCCTGCCTC GTTATCCTCC AGGCAGATGC TGTGGCACAC CCTGTGGTGC 
TGGGAATTGT GTGCCCGCGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863145.1
CDS	121..444
Translation	MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNSGILGGPGALAGLWGPAWTRKVAWSWERGPPASLSSRQMLWHTLWCWELCARV

Target ORF information:

RefSeq Version	XM_017007656.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007656.2

ORF Insert Sequence:

ATGGAGCTGA ACTCCCTGCT GATCCTGCTG GAGGCGGCCG AGTACCTGGA GCGCAGGGAT 
CGAGAGGCCG AGCACGGCTA CGCCTCGGTG CTGCCCTTCG ACGGCGACTT CGCCAGGGAG 
AAAACAAAGG CGGCCGGCCT GGTGCGCAAG GCCCCGAACA ACAGCGGCAT CCTGGGAGGC 
CCGGGAGCCC TGGCTGGCCT GTGGGGTCCT GCCTGGACAC GGAAGGTGGC CTGGAGCTGG 
GAGCGAGGTC CCCCTGCCTC GTTATCCTCC AGGCAGATGC TGTGGCACAC CCTGTGGTGC 
TGGGAATTGT GTGCCCGCGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MXD4 ( XM_017007656.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863145.1 Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu94855
Clone ID Related Accession (Same CDS sequence)	XM_017007656.2 , XM_017007656.1
Accession Version	XM_017007656.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 324bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	max dimerization protein 4 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTGA ACTCCCTGCT GATCCTGCTG GAGGCGGCCG AGTACCTGGA GCGCAGGGAT 
CGAGAGGCCG AGCACGGCTA CGCCTCGGTG CTGCCCTTCG ACGGCGACTT CGCCAGGGAG 
AAAACAAAGG CGGCCGGCCT GGTGCGCAAG GCCCCGAACA ACAGCGGCAT CCTGGGAGGC 
CCGGGAGCCC TGGCTGGCCT GTGGGGTCCT GCCTGGACAC GGAAGGTGGC CTGGAGCTGG 
GAGCGAGGTC CCCCTGCCTC GTTATCCTCC AGGCAGATGC TGTGGCACAC CCTGTGGTGC 
TGGGAATTGT GTGCCCGCGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863145.1
CDS	108..431
Translation	MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNSGILGGPGALAGLWGPAWTRKVAWSWERGPPASLSSRQMLWHTLWCWELCARV

Target ORF information:

RefSeq Version	XM_017007656.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MAX dimerization protein 4 (MXD4), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007656.1

ORF Insert Sequence:

ATGGAGCTGA ACTCCCTGCT GATCCTGCTG GAGGCGGCCG AGTACCTGGA GCGCAGGGAT 
CGAGAGGCCG AGCACGGCTA CGCCTCGGTG CTGCCCTTCG ACGGCGACTT CGCCAGGGAG 
AAAACAAAGG CGGCCGGCCT GGTGCGCAAG GCCCCGAACA ACAGCGGCAT CCTGGGAGGC 
CCGGGAGCCC TGGCTGGCCT GTGGGGTCCT GCCTGGACAC GGAAGGTGGC CTGGAGCTGG 
GAGCGAGGTC CCCCTGCCTC GTTATCCTCC AGGCAGATGC TGTGGCACAC CCTGTGGTGC 
TGGGAATTGT GTGCCCGCGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells.
Cancer biology & therapy13(13)1339-48(2012 Nov)
Yang W,Yang X,David G,Dorsey JF

Toward an understanding of the protein interaction network of the human liver.
Molecular systems biology7536(2011 Oct)
Wang J,Huo K,Ma L,Tang L,Li D,Huang X,Yuan Y,Li C,Wang W,Guan W,Chen H,Jin C,Wei J,Zhang W,Yang Y,Liu Q,Zhou Y,Zhang C,Wu Z,Xu W,Zhang Y,Liu T,Yu D,Zhang Y,Chen L,Zhu D,Zhong X,Kang L,Gan X,Yu X,Ma Q,Yan J,Zhou L,Liu Z,Zhu Y,Zhou T,He F,Yang X

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM

c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts.
Journal of cellular biochemistry96(5)1071-85(2005 Dec)
Marcotte R,Chen JM,Huard S,Wang E

Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin.
The Journal of steroid biochemistry and molecular biology94(1-3)203-8(2005 Feb)
Pope SN,Lee IR

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

[email protected]

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

MXD4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム