CYP2D6 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	CYP2D6
Entrez Gene ID	417981
Full Name	cytochrome P450 family 2 subfamily D member 6
Synonyms	CYP2D49,CYP2D6c
General protein information	Preferred Names cytochrome P450 family 2 subfamily D member 6 Names cytochrome P450 2D49 cytochrome P450 CYP2D49 cytochrome P450, family 2, subfamily D, polypeptide 49 cytochrome P450, family 2, subfamily D, polypeptide 6
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001195557.1	NP_001182486.1	cytochrome P450 2D49

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CYP2D6	NP_001035712.1
	CYP2D6	NP_001035308.1
Homo sapiens (human)	CYP2D6	NP_000097.3
Xenopus tropicalis (tropical clawed frog)	LOC100495518	XP_002933809.2
Xenopus tropicalis (tropical clawed frog)	cyp2d6	NP_001015719.1
Xenopus tropicalis (tropical clawed frog)	LOC100495359	XP_002933808.1
Xenopus tropicalis (tropical clawed frog)	LOC101731511	XP_004913819.1
Rattus norvegicus (Norway rat)	Cyp2d3	NP_775116.1
Gallus gallus (chicken)	CYP2D6	NP_001182486.1

Gene Ontology
Bibliography

Related articles in PubMed

Transcriptional regulation of chicken cytochrome P450 2D49 basal expression by CCAAT/enhancer-binding protein ? and hepatocyte nuclear factor 4?.
Yang Q, Tang S, Dong L, Chen Q, Liu X, Jiang J, Deng Y
The FEBS journal281(5)1379-92(2014 Mar)

Functional characterization of a first avian cytochrome P450 of the CYP2D subfamily (CYP2D49).
Cai H, Jiang J, Yang Q, Chen Q, Deng Y
PloS one7(6)e38395(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results of overexpressing C/EBPalpha and HNF4alpha in cultured cells confirmed that both C/EBPalpha and HNF4alpha contribute significantly to sustaining a high level of CYP2D49 transcription.
Title: Transcriptional regulation of chicken cytochrome P450 2D49 basal expression by CCAAT/enhancer-binding protein ? and hepatocyte nuclear factor 4?.

A cDNA encoding a novel CYP2D enzyme (CYP2D49) was cloned from the chicken liver for the first time.
Title: Functional characterization of a first avian cytochrome P450 of the CYP2D subfamily (CYP2D49).

The following CYP2D6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP2D6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa00406	NM_001195557.1 Latest version!	Gallus gallus cytochrome P450 family 2 subfamily D member 6 (CYP2D6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CYP2D6 ( NM_001195557.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001182486.1 Gallus gallus cytochrome P450 family 2 subfamily D member 6 (CYP2D6), mRNA.

Price & Availability↑

CloneID	OGa00406
Clone ID Related Accession (Same CDS sequence)	NM_001195557.1
Accession Version	NM_001195557.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Gallus gallus(chicken)
Product	cytochrome P450 2D49
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR354312.1. On Sep 17, 2010 this sequence version replaced XM_416219.2. ##Evidence-Data-START## Transcript exon combination :: CR354312.1, JQ241277.1 [ECO:0000332] ##Evidence-Data-END##

ATGACACTGC TCCTGTGGCT GTCATCTTGG AGCAACATCT CTGTACTGGG AGTTTTTCTT 
ACTGTCTTTA CCATACTTGT TGATTTCATG AAGCGCAGAA AGAAGTGGAG CCGTTACCCC 
CCAGGCCCAA TGCCACTGCC GTTTGTTGGG ACCATGCCAT ACGTTAATTA CTACAACCCG 
CATCTCTCCT TCGAGAAGTT TCGCAAGAAG TTTGGAAACA TTTTCAGTCT CCAGAACTGC 
TGGACCAATG TGGTAGTGCT GAATGGGTAC AAAACTGTGA AGGAAGCCCT GGTCAACAAA 
TCAGAGGACT TTGCTGACCG GCCATACATG CCAGTATATG AACATCTGGG CTATGGACAT 
AAATCTGAAG GGCTTGTTTT GGCAAGATAT GGACATCTCT GGAAAGAGCT AAGGAAATTC 
ACGCTCACTA CCCTGAGGAA TTTTGGGATG GGAAAGAAGT CCTTGGAAGA GCGAGTGACT 
GAGGAAGCAG GATTTTTGTG CTCTGCAATC AGTTCTGAAG GAGGTCATCC TTTTGATCCA 
CGTTTTCTTG TAAATAATGC AGTCTGCAAT GTGATCTGCA CCATTACCTA TGGAGAGCGT 
TTCGACTATG GAGACAAGAC ATTCAAGAAG CTGTTAACTT TGTTTGAAAA CTCTCTAAAT 
GAAGAAGCTG GATTCCTGCC TCAGCTTCTT AATGTGGCAC CTGTTTTGTT GCGCATCCCT 
GGACTGCCAC AGAAGATCTT TCCGTGCCAA AAGGCATACG TAGACTTCAC ACAAATGCTC 
ATAGATAAGC ACAAGGAGAC CTGGAACCCT GCTTACATCC GAGACTTCAC TGATGCATTT 
TTAAAGGAAA TGGCAAAGGG TAAGGAGGCT GAAGAGAATG GTTTCAATAA AAGCAACCTT 
ACTCTGGTGA CCGCAGACTT ACTTGTAGCT GGTTCTGAGA CCACCGCCAC CACCCTCCGA 
TGGGCGTTCC TGTTCATGCT TTTGTACCCA GAAATACAAA GTAAAGTCCA CAAAGAGATT 
GATAAGGTGA TTGGAAGAAA CCGACCGCCC ACCATGGCAG ACCAAGTGAA CATGCCCTAC 
ACCAATGCCG TCATCCATGA AGTACAACGC TTTGGGGACG TTGTTCCTAT GGGACTACCT 
CACATGACAT ACCGGGACAC TGAGCTTCAA GGTTTCTTCA TTCCCAAAGG GACGACAATC 
ATCACCAACT TGACTTCAGT ACTTAAGGAT GAGACGGCCT GGAAGAAGCC AAATGAATTT 
TACCCTGAAC ACTTTCTGAA TGAGAATGGG CAATTTGTGA GACCAGAGGC CTTCTTGCCC 
TTCTCTGCAG GTCGACGTGC CTGCCTGGGG GAACAGCTGA CCAGGATGGA GCTTTTCATC 
TTCTTCACCA CTCTCATGCA GAAGTTCACC TTTGTGTTCC CTGAAGATCA GCCCAGGCCA 
CGAGAGGACA GTCACTTTGC TTTTACAAAC AGTCCACACC CATACCAGTT GCGAGCTGTT 
CCAAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001182486.1
CDS	165..1673
Translation	MTLLLWLSSWSNISVLGVFLTVFTILVDFMKRRKKWSRYPPGPMPLPFVGTMPYVNYYNPHLSFEKFRKKFGNIFSLQNCWTNVVVLNGYKTVKEALVNKSEDFADRPYMPVYEHLGYGHKSEGLVLARYGHLWKELRKFTLTTLRNFGMGKKSLEERVTEEAGFLCSAISSEGGHPFDPRFLVNNAVCNVICTITYGERFDYGDKTFKKLLTLFENSLNEEAGFLPQLLNVAPVLLRIPGLPQKIFPCQKAYVDFTQMLIDKHKETWNPAYIRDFTDAFLKEMAKGKEAEENGFNKSNLTLVTADLLVAGSETTATTLRWAFLFMLLYPEIQSKVHKEIDKVIGRNRPPTMADQVNMPYTNAVIHEVQRFGDVVPMGLPHMTYRDTELQGFFIPKGTTIITNLTSVLKDETAWKKPNEFYPEHFLNENGQFVRPEAFLPFSAGRRACLGEQLTRMELFIFFTTLMQKFTFVFPEDQPRPREDSHFAFTNSPHPYQLRAVPR

Target ORF information:

RefSeq Version	NM_001195557.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus cytochrome P450 family 2 subfamily D member 6 (CYP2D6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001195557.1

ORF Insert Sequence:

ATGACACTGC TCCTGTGGCT GTCATCTTGG AGCAACATCT CTGTACTGGG AGTTTTTCTT 
ACTGTCTTTA CCATACTTGT TGATTTCATG AAGCGCAGAA AGAAGTGGAG CCGTTACCCC 
CCAGGCCCAA TGCCACTGCC GTTTGTTGGG ACCATGCCAT ACGTTAATTA CTACAACCCG 
CATCTCTCCT TCGAGAAGTT TCGCAAGAAG TTTGGAAACA TTTTCAGTCT CCAGAACTGC 
TGGACCAATG TGGTAGTGCT GAATGGGTAC AAAACTGTGA AGGAAGCCCT GGTCAACAAA 
TCAGAGGACT TTGCTGACCG GCCATACATG CCAGTATATG AACATCTGGG CTATGGACAT 
AAATCTGAAG GGCTTGTTTT GGCAAGATAT GGACATCTCT GGAAAGAGCT AAGGAAATTC 
ACGCTCACTA CCCTGAGGAA TTTTGGGATG GGAAAGAAGT CCTTGGAAGA GCGAGTGACT 
GAGGAAGCAG GATTTTTGTG CTCTGCAATC AGTTCTGAAG GAGGTCATCC TTTTGATCCA 
CGTTTTCTTG TAAATAATGC AGTCTGCAAT GTGATCTGCA CCATTACCTA TGGAGAGCGT 
TTCGACTATG GAGACAAGAC ATTCAAGAAG CTGTTAACTT TGTTTGAAAA CTCTCTAAAT 
GAAGAAGCTG GATTCCTGCC TCAGCTTCTT AATGTGGCAC CTGTTTTGTT GCGCATCCCT 
GGACTGCCAC AGAAGATCTT TCCGTGCCAA AAGGCATACG TAGACTTCAC ACAAATGCTC 
ATAGATAAGC ACAAGGAGAC CTGGAACCCT GCTTACATCC GAGACTTCAC TGATGCATTT 
TTAAAGGAAA TGGCAAAGGG TAAGGAGGCT GAAGAGAATG GTTTCAATAA AAGCAACCTT 
ACTCTGGTGA CCGCAGACTT ACTTGTAGCT GGTTCTGAGA CCACCGCCAC CACCCTCCGA 
TGGGCGTTCC TGTTCATGCT TTTGTACCCA GAAATACAAA GTAAAGTCCA CAAAGAGATT 
GATAAGGTGA TTGGAAGAAA CCGACCGCCC ACCATGGCAG ACCAAGTGAA CATGCCCTAC 
ACCAATGCCG TCATCCATGA AGTACAACGC TTTGGGGACG TTGTTCCTAT GGGACTACCT 
CACATGACAT ACCGGGACAC TGAGCTTCAA GGTTTCTTCA TTCCCAAAGG GACGACAATC 
ATCACCAACT TGACTTCAGT ACTTAAGGAT GAGACGGCCT GGAAGAAGCC AAATGAATTT 
TACCCTGAAC ACTTTCTGAA TGAGAATGGG CAATTTGTGA GACCAGAGGC CTTCTTGCCC 
TTCTCTGCAG GTCGACGTGC CTGCCTGGGG GAACAGCTGA CCAGGATGGA GCTTTTCATC 
TTCTTCACCA CTCTCATGCA GAAGTTCACC TTTGTGTTCC CTGAAGATCA GCCCAGGCCA 
CGAGAGGACA GTCACTTTGC TTTTACAAAC AGTCCACACC CATACCAGTT GCGAGCTGTT 
CCAAGATAA