CCN3 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCN3
Entrez Gene ID	396204
Full Name	nephroblastoma overexpressed
General protein information	Preferred Names nephroblastoma overexpressed Names protein NOV CCN family member 3 nephroblastoma-overexpressed gene protein
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205268.1	NP_990599.1	CCN family member 3 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	NOV	XP_001142595.1
Xenopus tropicalis (tropical clawed frog)	nov	XP_002938019.1
Bos taurus (cattle)	NOV	NP_001095852.1
Mus musculus (house mouse)	Nov	NP_035060.1
Rattus norvegicus (Norway rat)	Nov	NP_110495.1
Homo sapiens (human)	NOV	NP_002505.1
	NOV	XP_001097136.1
Canis lupus familiaris (dog)	NOV	XP_532317.3
Gallus gallus (chicken)	NOV	NP_990599.1

Gene Ontology
Bibliography

Related articles in PubMed

Temporal and spatial expression of CCN3 during retina development.
Laurent M, Maryvonne L, Le Dr?au G, Gwenva?l le D, Guillonneau X, Xavier G, Leli?vre E, C?cile LE, Slembrouck A, Am?lie S, Goureau O, Olivier G, Martinerie C, C?cile M, Marx M, Maria M
Developmental neurobiology72(11)1363-75(2012 Nov)

Defining the earliest transcriptional steps of chondrogenic progenitor specification during the formation of the digits in the embryonic limb.
Lorda-Diez CI, Montero JA, Diaz-Mendoza MJ, Garcia-Porrero JA, Hurle JM
PloS one6(9)e24546(2011)

Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas.
Joliot V, Martinerie C, Dambrine G, Plassiart G, Brisac M, Crochet J, Perbal B
Molecular and cellular biology12(1)10-21(1992 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results establish the expression pattern of CCN3 in the developing retina, and show CCN3 expression is induced by activated BMP signaling, whereas Notch signaling decreases CCN3 mRNA and protein levels in Muller cells and has no effect in retinal neurons.
Title: Temporal and spatial expression of CCN3 during retina development.

The expression of NOV was intense in the developing tendons and in the developing joints, whereas the chondrogenic blastemas were negative for NOV transcripts. NOV induced intense upregulation of Tenascin C and, at a reduced level, of alpha 5 Integrin, Sox9, and Activin beta-A.
Title: Defining the earliest transcriptional steps of chondrogenic progenitor specification during the formation of the digits in the embryonic limb.

The following CCN3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCN3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa27945	NM_205268.1 Latest version!	Gallus gallus nephroblastoma overexpressed (CCN3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCN3 ( NM_205268.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990599.1 Gallus gallus nephroblastoma overexpressed (CCN3), mRNA.

Price & Availability↑

CloneID	OGa27945
Clone ID Related Accession (Same CDS sequence)	NM_205268.1
Accession Version	NM_205268.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Gallus gallus(chicken)
Product	CCN family member 3 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X59284.1. ##Evidence-Data-START## Transcript exon combination :: X59284.1 [ECO:0000332] ##Evidence-Data-END##

ATGGAGACGG GCGGCGGGCA GGGGCTGCCC GTCCTGCTGC TGCTCCTGCT CCTCCTCCGG 
CCGTGCGAGG TGAGCGGGCG GGAGGCGGCG TGCCCCCGGC CCTGCGGCGG GCGCTGCCCC 
GCGGAGCCGC CGCGCTGCGC CCCGGGAGTG CCCGCCGTGC TGGACGGCTG CGGCTGCTGC 
CTGGTGTGCG CCCGGCAGCG CGGCGAGAGC TGCTCCCCTC TGCTGCCCTG CGACGAGAGC 
GGCGGCCTCT ACTGCGACCG CGGCCCCGAG GACGGCGGCG GCGCCGGCAT CTGCATGGTG 
CTGGAAGGGG ACAACTGCGT GTTCGATGGG ATGATTTACC GCAACGGGGA GACGTTCCAG 
CCCAGCTGCA AGTACCAGTG CACCTGCCGG GACGGGCAGA TCGGGTGCCT GCCCCGCTGC 
AACCTGGGCC TGCTGCTCCC CGGCCCCGAC TGCCCCTTCC CGCGGAAGAT CGAAGTCCCC 
GGAGAGTGCT GCGAGAAGTG GGTGTGCGAC CCCAGGGATG AAGTGCTCCT GGGAGGCTTT 
GCTATGGCTG CATACAGACA GGAGGCCACA CTTGGGATAG ACGTGTCTGA TTCAAGTGCC 
AATTGTATTG AACAGACAAC AGAATGGAGT GCTTGTTCCA AAAGCTGTGG AATGGGCTTT 
TCTACCCGTG TTACCAACAG AAATCAGCAG TGTGAGATGG TGAAGCAGAC ACGACTTTGC 
ATGATGAGAC CTTGTGAAAA CGAAGAGCCA TCTGATAAGA AAGGAAAAAA ATGTATCCAA 
ACAAAGAAAT CCATGAAAGC TGTTCGTTTT GAATACAAGA ACTGCACCAG TGTGCAGACT 
TACAAACCTC GTTACTGTGG CCTCTGCAAT GATGGGCGAT GCTGTACCCC ACACAACACC 
AAAACGATTC AAGTTGAGTT CCGCTGTCCT CAGGGCAAAT TCCTAAAAAA GCCAATGATG 
TTGATCAATA CCTGTGTCTG TCATGGTAAC TGTCCTCAGA GTAACAATGC TTTCTTCCAG 
CCATTAGATC CCATGTCTAG TGAAGCAAAA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990599.1
CDS	25..1080
Translation	METGGGQGLPVLLLLLLLLRPCEVSGREAACPRPCGGRCPAEPPRCAPGVPAVLDGCGCCLVCARQRGESCSPLLPCDESGGLYCDRGPEDGGGAGICMVLEGDNCVFDGMIYRNGETFQPSCKYQCTCRDGQIGCLPRCNLGLLLPGPDCPFPRKIEVPGECCEKWVCDPRDEVLLGGFAMAAYRQEATLGIDVSDSSANCIEQTTEWSACSKSCGMGFSTRVTNRNQQCEMVKQTRLCMMRPCENEEPSDKKGKKCIQTKKSMKAVRFEYKNCTSVQTYKPRYCGLCNDGRCCTPHNTKTIQVEFRCPQGKFLKKPMMLINTCVCHGNCPQSNNAFFQPLDPMSSEAKI

Target ORF information:

RefSeq Version	NM_205268.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus nephroblastoma overexpressed (CCN3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205268.1

ORF Insert Sequence:

ATGGAGACGG GCGGCGGGCA GGGGCTGCCC GTCCTGCTGC TGCTCCTGCT CCTCCTCCGG 
CCGTGCGAGG TGAGCGGGCG GGAGGCGGCG TGCCCCCGGC CCTGCGGCGG GCGCTGCCCC 
GCGGAGCCGC CGCGCTGCGC CCCGGGAGTG CCCGCCGTGC TGGACGGCTG CGGCTGCTGC 
CTGGTGTGCG CCCGGCAGCG CGGCGAGAGC TGCTCCCCTC TGCTGCCCTG CGACGAGAGC 
GGCGGCCTCT ACTGCGACCG CGGCCCCGAG GACGGCGGCG GCGCCGGCAT CTGCATGGTG 
CTGGAAGGGG ACAACTGCGT GTTCGATGGG ATGATTTACC GCAACGGGGA GACGTTCCAG 
CCCAGCTGCA AGTACCAGTG CACCTGCCGG GACGGGCAGA TCGGGTGCCT GCCCCGCTGC 
AACCTGGGCC TGCTGCTCCC CGGCCCCGAC TGCCCCTTCC CGCGGAAGAT CGAAGTCCCC 
GGAGAGTGCT GCGAGAAGTG GGTGTGCGAC CCCAGGGATG AAGTGCTCCT GGGAGGCTTT 
GCTATGGCTG CATACAGACA GGAGGCCACA CTTGGGATAG ACGTGTCTGA TTCAAGTGCC 
AATTGTATTG AACAGACAAC AGAATGGAGT GCTTGTTCCA AAAGCTGTGG AATGGGCTTT 
TCTACCCGTG TTACCAACAG AAATCAGCAG TGTGAGATGG TGAAGCAGAC ACGACTTTGC 
ATGATGAGAC CTTGTGAAAA CGAAGAGCCA TCTGATAAGA AAGGAAAAAA ATGTATCCAA 
ACAAAGAAAT CCATGAAAGC TGTTCGTTTT GAATACAAGA ACTGCACCAG TGTGCAGACT 
TACAAACCTC GTTACTGTGG CCTCTGCAAT GATGGGCGAT GCTGTACCCC ACACAACACC 
AAAACGATTC AAGTTGAGTT CCGCTGTCCT CAGGGCAAAT TCCTAAAAAA GCCAATGATG 
TTGATCAATA CCTGTGTCTG TCATGGTAAC TGTCCTCAGA GTAACAATGC TTTCTTCCAG 
CCATTAGATC CCATGTCTAG TGAAGCAAAA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Temporal and spatial expression of CCN3 during retina development.
Developmental neurobiology72(11)1363-75(2012 Nov)
Laurent M,Maryvonne L,Le Dr?au G,Gwenva?l le D,Guillonneau X,Xavier G,Leli?vre E,C?cile LE,Slembrouck A,Am?lie S,Goureau O,Olivier G,Martinerie C,C?cile M,Marx M,Maria M

Defining the earliest transcriptional steps of chondrogenic progenitor specification during the formation of the digits in the embryonic limb.
PloS one6(9)e24546(2011)
Lorda-Diez CI,Montero JA,Diaz-Mendoza MJ,Garcia-Porrero JA,Hurle JM

Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas.
Molecular and cellular biology12(1)10-21(1992 Jan)
Joliot V,Martinerie C,Dambrine G,Plassiart G,Brisac M,Crochet J,Perbal B