IL17A cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL17A
Entrez Gene ID	395111
Full Name	interleukin 17A
Synonyms	ChIL-17,IL-17,IL-17F,IL17,interleukin-17A
General protein information	Preferred Names interleukin 17A Names interleukin-17A interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) interleukin-17
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_204460.1	NP_989791.1	interleukin-17A precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	IL17F	XP_527409.2
Rattus norvegicus (Norway rat)	Il17f	NP_001015011.1
Canis lupus familiaris (dog)	IL17F	XP_538959.1
Xenopus tropicalis (tropical clawed frog)	il17f	XP_004915036.1
Xenopus tropicalis (tropical clawed frog)	LOC101734106	XP_004915037.1
Homo sapiens (human)	IL17F	NP_443104.1
	IL17F	XP_001106517.1
Bos taurus (cattle)	IL17F	NP_001179011.1
Gallus gallus (chicken)	IL17F	NP_989791.1
Mus musculus (house mouse)	Il17f	NP_665855.2

Gene Ontology
Bibliography

Related articles in PubMed

Chicken IL-17A is expressed in ?? and ?? T cell subsets and binds to a receptor present on macrophages, and T cells.
Walliser I, G?bel TW
Developmental and comparative immunology8144-53(2018 Apr)

Interaction of TGF-?4 and IL-17 with IgA secretion in the intestine of chickens fed with E. faecium AL41 and challenged with S. Enteritidis.
Karaffov? V, Bob?kov? K, Hus?kov? E, Levkut M, Herich R, Revajov? V, Levkutov? M, Levkut M
Research in veterinary science10075-9(2015 Jun)

The expression dynamics of IL-17 and Th17 response relative cytokines in the trachea and spleen of chickens after infection with Cryptosporidium baileyi.
Zhao GH, Cheng WY, Wang W, Jia YQ, Fang YQ, Du SZ, Yu SK
Parasites & vectors7212(2014 May)

IL-17A regulates Eimeria tenella schizont maturation and migration in avian coccidiosis.
Del Cacho E, Gallego M, Lillehoj HS, Qu?lez J, Lillehoj EP, Ramo A, S?nchez-Acedo C
Veterinary research4525(2014 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

There was a beneficial effect of Enterococcus faecium on IgA production and secretion in chicken intestine. IgA also contributed in decrease of intestinal Salmonella Enteritidis, and cytokines TGF-beta4 and IL-17 contributed to increased IgA secretion.
Title: Interaction of TGF-?4 and IL-17 with IgA secretion in the intestine of chickens fed with E. faecium AL41 and challenged with S. Enteritidis.

The results in the present study suggest that IL-17 may play a role in immunity against Cryptosporidium infection, and provide basic information for determining the role of Th17 cell in Cryptosporidium infection
Title: The expression dynamics of IL-17 and Th17 response relative cytokines in the trachea and spleen of chickens after infection with Cryptosporidium baileyi.

Administration of an IL17A neutralizing Ab to Eimeria tenella-infected chickens inhibits the migration of parasitized epithelial cells, markedly reduces the production of reactive oxygen species and matrix metalloproteinase-9, and decreases cecal lesions.
Title: IL-17A regulates Eimeria tenella schizont maturation and migration in avian coccidiosis.

The following IL17A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL17A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa24933	NM_204460.1 Latest version!	Gallus gallus interleukin 17A (IL17A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL17A ( NM_204460.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_989791.1 Gallus gallus interleukin 17A (IL17A), mRNA.

Price & Availability↑

CloneID	OGa24933
Clone ID Related Accession (Same CDS sequence)	NM_204460.1
Accession Version	NM_204460.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 510bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-10
Organism	Gallus gallus(chicken)
Product	interleukin-17A precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ493595.1. ##Evidence-Data-START## Transcript exon combination :: AJ493595.1 [ECO:0000332] ##Evidence-Data-END##

ATGTCTCCGA TCCCTTATTC TCCTCTGTTC AGACCACTGC TGTTGGTGTT GCTGGCCATG 
TTGTCAGCCA GCATTTCTGC ACATGGGAAG GTGATACGGC CAGGACTCGA GCCAGAGAGC 
CTCTTCAAGA AAGCAGATGC TGGATGCCTA ACCCAAAAAG ATGGAAAATT CCCCCAAACT 
GTGAGAGTCA ACATAAGCAT CAGCAACATG AACCAGGATA CCAAAGTGAC CCTTGATATC 
AGCAAACGCT CACTGGCTCC ATGGGATTAC AGGATCGATG AGGACCACAA CCGCTTCCCC 
CGCTTGGTTG CTGATGCCCA GTGCCGCCAT TCCAGGTGCG TGAACTCGGC TGGGCAGCTG 
GACCACAGCG TCAACTCCGT GCCCATCAAA CAGGAGATCC TCGTCCTCCG CCGCGAGCCG 
AAGGGCTGCC AGCACTCGTA CCGCCTGGAG AAGAAAATGA TCACCGTGGG CTGCACGTGT 
GTCACCCCAC TGATCCAGCA CCAGGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_989791.1
CDS	64..573
Translation	MSPIPYSPLFRPLLLVLLAMLSASISAHGKVIRPGLEPESLFKKADAGCLTQKDGKFPQTVRVNISISNMNQDTKVTLDISKRSLAPWDYRIDEDHNRFPRLVADAQCRHSRCVNSAGQLDHSVNSVPIKQEILVLRREPKGCQHSYRLEKKMITVGCTCVTPLIQHQA

Target ORF information:

RefSeq Version	NM_204460.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus interleukin 17A (IL17A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_204460.1

ORF Insert Sequence:

ATGTCTCCGA TCCCTTATTC TCCTCTGTTC AGACCACTGC TGTTGGTGTT GCTGGCCATG 
TTGTCAGCCA GCATTTCTGC ACATGGGAAG GTGATACGGC CAGGACTCGA GCCAGAGAGC 
CTCTTCAAGA AAGCAGATGC TGGATGCCTA ACCCAAAAAG ATGGAAAATT CCCCCAAACT 
GTGAGAGTCA ACATAAGCAT CAGCAACATG AACCAGGATA CCAAAGTGAC CCTTGATATC 
AGCAAACGCT CACTGGCTCC ATGGGATTAC AGGATCGATG AGGACCACAA CCGCTTCCCC 
CGCTTGGTTG CTGATGCCCA GTGCCGCCAT TCCAGGTGCG TGAACTCGGC TGGGCAGCTG 
GACCACAGCG TCAACTCCGT GCCCATCAAA CAGGAGATCC TCGTCCTCCG CCGCGAGCCG 
AAGGGCTGCC AGCACTCGTA CCGCCTGGAG AAGAAAATGA TCACCGTGGG CTGCACGTGT 
GTCACCCCAC TGATCCAGCA CCAGGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chicken IL-17A is expressed in ?? and ?? T cell subsets and binds to a receptor present on macrophages, and T cells.
Developmental and comparative immunology8144-53(2018 Apr)
Walliser I,G?bel TW

Interaction of TGF-?4 and IL-17 with IgA secretion in the intestine of chickens fed with E. faecium AL41 and challenged with S. Enteritidis.
Research in veterinary science10075-9(2015 Jun)
Karaffov? V,Bob?kov? K,Hus?kov? E,Levkut M,Herich R,Revajov? V,Levkutov? M,Levkut M

The expression dynamics of IL-17 and Th17 response relative cytokines in the trachea and spleen of chickens after infection with Cryptosporidium baileyi.
Parasites & vectors7212(2014 May)
Zhao GH,Cheng WY,Wang W,Jia YQ,Fang YQ,Du SZ,Yu SK

IL-17A regulates Eimeria tenella schizont maturation and migration in avian coccidiosis.
Veterinary research4525(2014 Feb)
Del Cacho E,Gallego M,Lillehoj HS,Qu?lez J,Lillehoj EP,Ramo A,S?nchez-Acedo C