ACVR2B cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	ACVR2B
Entrez Gene ID	374213
Full Name	activin A receptor type 2B
Synonyms	ACTR-IIB,ActRIIB
General protein information	Preferred Names activin A receptor type 2B Names activin receptor type-2B activin A receptor, type IIB activin receptor type 2B activin receptor type IIB
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_204317.1	NP_989648.1	activin receptor type-2B precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ACVR2B	XP_542709.2
Homo sapiens (human)	ACVR2B	NP_001097.2
Bos taurus (cattle)	ACVR2B	NP_776920.1
Gallus gallus (chicken)	ACVR2B	NP_989648.1
	ACVR2B	XP_001084713.1
Danio rerio (zebrafish)	acvr2b	NP_571285.1
Pan troglodytes (chimpanzee)	ACVR2B	XP_516369.2
Mus musculus (house mouse)	Acvr2b	NP_031423.1
Rattus norvegicus (Norway rat)	Acvr2b	NP_113742.1
Xenopus tropicalis (tropical clawed frog)	acvr2b	NP_001006871.1

Gene Ontology
Bibliography

Related articles in PubMed

Signaling via the transcriptionally regulated activin receptor 2B is a novel mediator of neuronal cell death during chicken ciliary ganglion development.
Koszinowski S, Buss K, Kaehlcke K, Krieglstein K
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience4198-104(2015 Apr)

Activin potentiates proliferation in mature avian auditory sensory epithelium.
McCullar JS, Ty S, Campbell S, Oesterle EC
The Journal of neuroscience : the official journal of the Society for Neuroscience30(2)478-90(2010 Jan)

Differential expression of mRNAs encoding the putative inhibin co-receptor (betaglycan) and activin type-I and type-II receptors in preovulatory and prehierarchical follicles of the laying hen ovary.
Lovell TM, Knight PG, Gladwell RT
The Journal of endocrinology188(2)241-9(2006 Feb)

Variation in pituitary expression of mRNAs encoding the putative inhibin co-receptor (betaglycan) and type-I and type-II activin receptors during the chicken ovulatory cycle.
Lovell TM, Knight PG, Gladwell RT
The Journal of endocrinology186(3)447-55(2005 Sep)

The activin signaling pathway promotes differentiation of dI3 interneurons in the spinal neural tube.
Timmer J, Chesnutt C, Niswander L
Developmental biology285(1)1-10(2005 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonstrated that the role of ACVR2B expression in ciliary ganglion neuronal development, investigating its function in neuronal differentiation and ontogenetic cell death.
Title: Signaling via the transcriptionally regulated activin receptor 2B is a novel mediator of neuronal cell death during chicken ciliary ganglion development.

The following ACVR2B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ACVR2B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa27275	NM_204317.1 Latest version!	Gallus gallus activin A receptor type 2B (ACVR2B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ACVR2B ( NM_204317.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_989648.1 Gallus gallus activin A receptor type 2B (ACVR2B), mRNA.

Price & Availability↑

CloneID	OGa27275
Clone ID Related Accession (Same CDS sequence)	NM_204317.1
Accession Version	NM_204317.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1539bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Gallus gallus(chicken)
Product	activin receptor type-2B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U31223.1. ##Evidence-Data-START## CDS exon combination :: U31223.1 [ECO:0000331] ##Evidence-Data-END##

ATGAGCGCTT CGTGGCTGAC TTTGGCCGTG CTCTGTGCAA CTTTGGGCGC AGGACCAGGT 
CACGGGGAGG CAGAGACGAG GGAATGCATT TACTACAACG CCAACTGGGA GCTGGAGAAG 
ACCAACCAGA GTGGCGTGGA GCGCTGCGAG GGGGAGAAGG ACAAGCGGCT CCACTGCTAC 
GCCTCCTGGA GAAACAACTC GGGATCCATT GAGCTGGTGA AGAAAGGCTG CTGGTTAGAT 
GACTTCAACT GTTATGACAG GCAGGAGTGC GTAGCCACAG AAGAAAACCC TCAAGTGTTT 
TTCTGCTGCT GCGAGGGCAA CTACTGCAAT GAGAAATTCA CCCACTTGCC TGAAGTAACT 
GGCCCAGAAG TCATATATGA GCCGCCACCA CCAACGCCCT CCCTGCTTAA CATCCTGGTG 
TACTCTCTGC TGCCCATCGC TGTCCTGTCA GTGGCCATCC TCTTGGCCTT CTGGATGTAT 
CGGCACCGCA AGCCTCCCTA CGGGCACGTT GACATCAATG AGGACCCCGG CCCACCACCT 
CCTTCTCCCC TGGTTGGCCT AAAACCTCTA CAGCTCCTGG AGATCAAAGC CAGGGGACGC 
TTTGGCTGCG TGTGGAAGGC TCAGCTGATG AATGACTACG TAGCAGTGAA AATCTTCCCA 
ATTCAGGATA AGCAATCTTG GCAGAGTGAG AGGGAGATTT TCAATACTCC TGGCATGAAG 
CATGAAAACC TTTTGCAATT TATCGCAGCA GAAAAGAGAG GGACAAACCT AGAGACAGAG 
CTCTGGCTGA TCACAGCGTT CCACGACAAG GGCTCTCTCA CGGATTACCT GAAGGGCAAT 
ATCATCAGCT GGAATGAGCT CTGCCATGTT GCAGAAACCA TGGCCCGTGG CTTGTCTTAC 
CTCCATGAGG ACGTCCCGTG GTGCAAGGGT GAAGGACACA AACCTGCTAT AGCACACAGG 
GACTTCAAGA GTAAAAACGT CTTGCTGAAG AACGACTTAA CGGCGGTGCT AGCCGATTTT 
GGTCTTGCTG TACGGTTTGA ACCTGGAAAA CCTCCAGGGG ACACCCATGG ACAGGTGGGA 
ACAAGGAGGT ATATGGCTCC TGAAGTGTTA GAGGGAGCAA TCAACTTCCA ACGAGACGCC 
TTCCTGAGAA TAGACATGTA CGCAATGGGA CTGGTATTGT GGGAGTTAGT CTCCAGATGT 
AGAGCAGTTG ATGGTCCAGT GGATGAATAC ATGCTGCCTT TTGAAGAAGA AATAGGTCAG 
CACCCATCCC TTGAGGACCT GCAAGAAGTG GTGGTTCACA AGAAGATGCG CCCCGTCTTC 
AAGGATCATT GGCTGAAACA CCCTGGCTTG GCGCAGCTCT GCGTGACCAT CGAAGAGTGC 
TGGGACCACG ACGCAGAGGC TCGGCTCTCG GCAGGCTGTG TCGAGGAGCG CATTGCTCAG 
ATCCGCAAAT CCGTAAACGG CACTACCTCG GACTGCCTTG TCTCCATCGT GACGTCCGTC 
ACCAACGTGG ACTTGCCGCC CAAAGAGTCC AGTATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_989648.1
CDS	265..1803
Translation	MSASWLTLAVLCATLGAGPGHGEAETRECIYYNANWELEKTNQSGVERCEGEKDKRLHCYASWRNNSGSIELVKKGCWLDDFNCYDRQECVATEENPQVFFCCCEGNYCNEKFTHLPEVTGPEVIYEPPPPTPSLLNILVYSLLPIAVLSVAILLAFWMYRHRKPPYGHVDINEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDYVAVKIFPIQDKQSWQSEREIFNTPGMKHENLLQFIAAEKRGTNLETELWLITAFHDKGSLTDYLKGNIISWNELCHVAETMARGLSYLHEDVPWCKGEGHKPAIAHRDFKSKNVLLKNDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCRAVDGPVDEYMLPFEEEIGQHPSLEDLQEVVVHKKMRPVFKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERIAQIRKSVNGTTSDCLVSIVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	NM_204317.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus activin A receptor type 2B (ACVR2B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_204317.1

ORF Insert Sequence:

ATGAGCGCTT CGTGGCTGAC TTTGGCCGTG CTCTGTGCAA CTTTGGGCGC AGGACCAGGT 
CACGGGGAGG CAGAGACGAG GGAATGCATT TACTACAACG CCAACTGGGA GCTGGAGAAG 
ACCAACCAGA GTGGCGTGGA GCGCTGCGAG GGGGAGAAGG ACAAGCGGCT CCACTGCTAC 
GCCTCCTGGA GAAACAACTC GGGATCCATT GAGCTGGTGA AGAAAGGCTG CTGGTTAGAT 
GACTTCAACT GTTATGACAG GCAGGAGTGC GTAGCCACAG AAGAAAACCC TCAAGTGTTT 
TTCTGCTGCT GCGAGGGCAA CTACTGCAAT GAGAAATTCA CCCACTTGCC TGAAGTAACT 
GGCCCAGAAG TCATATATGA GCCGCCACCA CCAACGCCCT CCCTGCTTAA CATCCTGGTG 
TACTCTCTGC TGCCCATCGC TGTCCTGTCA GTGGCCATCC TCTTGGCCTT CTGGATGTAT 
CGGCACCGCA AGCCTCCCTA CGGGCACGTT GACATCAATG AGGACCCCGG CCCACCACCT 
CCTTCTCCCC TGGTTGGCCT AAAACCTCTA CAGCTCCTGG AGATCAAAGC CAGGGGACGC 
TTTGGCTGCG TGTGGAAGGC TCAGCTGATG AATGACTACG TAGCAGTGAA AATCTTCCCA 
ATTCAGGATA AGCAATCTTG GCAGAGTGAG AGGGAGATTT TCAATACTCC TGGCATGAAG 
CATGAAAACC TTTTGCAATT TATCGCAGCA GAAAAGAGAG GGACAAACCT AGAGACAGAG 
CTCTGGCTGA TCACAGCGTT CCACGACAAG GGCTCTCTCA CGGATTACCT GAAGGGCAAT 
ATCATCAGCT GGAATGAGCT CTGCCATGTT GCAGAAACCA TGGCCCGTGG CTTGTCTTAC 
CTCCATGAGG ACGTCCCGTG GTGCAAGGGT GAAGGACACA AACCTGCTAT AGCACACAGG 
GACTTCAAGA GTAAAAACGT CTTGCTGAAG AACGACTTAA CGGCGGTGCT AGCCGATTTT 
GGTCTTGCTG TACGGTTTGA ACCTGGAAAA CCTCCAGGGG ACACCCATGG ACAGGTGGGA 
ACAAGGAGGT ATATGGCTCC TGAAGTGTTA GAGGGAGCAA TCAACTTCCA ACGAGACGCC 
TTCCTGAGAA TAGACATGTA CGCAATGGGA CTGGTATTGT GGGAGTTAGT CTCCAGATGT 
AGAGCAGTTG ATGGTCCAGT GGATGAATAC ATGCTGCCTT TTGAAGAAGA AATAGGTCAG 
CACCCATCCC TTGAGGACCT GCAAGAAGTG GTGGTTCACA AGAAGATGCG CCCCGTCTTC 
AAGGATCATT GGCTGAAACA CCCTGGCTTG GCGCAGCTCT GCGTGACCAT CGAAGAGTGC 
TGGGACCACG ACGCAGAGGC TCGGCTCTCG GCAGGCTGTG TCGAGGAGCG CATTGCTCAG 
ATCCGCAAAT CCGTAAACGG CACTACCTCG GACTGCCTTG TCTCCATCGT GACGTCCGTC 
ACCAACGTGG ACTTGCCGCC CAAAGAGTCC AGTATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Signaling via the transcriptionally regulated activin receptor 2B is a novel mediator of neuronal cell death during chicken ciliary ganglion development.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience4198-104(2015 Apr)
Koszinowski S,Buss K,Kaehlcke K,Krieglstein K

Activin potentiates proliferation in mature avian auditory sensory epithelium.
The Journal of neuroscience : the official journal of the Society for Neuroscience30(2)478-90(2010 Jan)
McCullar JS,Ty S,Campbell S,Oesterle EC

Differential expression of mRNAs encoding the putative inhibin co-receptor (betaglycan) and activin type-I and type-II receptors in preovulatory and prehierarchical follicles of the laying hen ovary.
The Journal of endocrinology188(2)241-9(2006 Feb)
Lovell TM,Knight PG,Gladwell RT

Variation in pituitary expression of mRNAs encoding the putative inhibin co-receptor (betaglycan) and type-I and type-II activin receptors during the chicken ovulatory cycle.
The Journal of endocrinology186(3)447-55(2005 Sep)
Lovell TM,Knight PG,Gladwell RT

The activin signaling pathway promotes differentiation of dI3 interneurons in the spinal neural tube.
Developmental biology285(1)1-10(2005 Sep)
Timmer J,Chesnutt C,Niswander L