hmx1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	hmx1
Entrez Gene ID	797503
Full Name	H6 family homeobox 1
Synonyms	Nkx5-3,im:7155045,nkx5.3,zgc:172164
General protein information	Preferred Names H6 family homeobox 1 Names homeobox protein HMX1 H6 homeo box 1 homeobox transcription factor SOHo
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001113526.1	NP_001106998.1	homeobox protein HMX1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	HMX1	NP_990864.1
Xenopus tropicalis (tropical clawed frog)	hmx1	XP_002940264.2
Danio rerio (zebrafish)	hmx1	NP_001106998.1

Gene Ontology
Bibliography

Related articles in PubMed

Xenopus laevis Nkx5.3 and sensory organ homeobox (SOHo) are expressed in developing sensory organs and ganglia of the head and anterior trunk.
Kelly LE, El-Hodiri HM
Development genes and evolution226(6)423-428(2016 Nov)

Genes and signaling networks regulated during zebrafish optic vesicle morphogenesis.
Yin J, Morrissey ME, Shine L, Kennedy C, Higgins DG, Kennedy BN
BMC genomics15825(2014 Sep)

A dimerized HMX1 inhibits EPHA6/epha4b in mouse and zebrafish retinas.
Marcelli F, Boisset G, Schorderet DF
PloS one9(6)e100096(2014)

Apoptotic and proliferative defects characterize ocular development in a microphthalmic BMP model.
French CR, Stach TR, March LD, Lehmann OJ, Waskiewicz AJ
Investigative ophthalmology & visual science54(7)4636-47(2013 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

EPHA6, a gene implicated in retinal axon guidance, is one of HMX1 targets in eye development.
Title: A dimerized HMX1 inhibits EPHA6/epha4b in mouse and zebrafish retinas.

The following hmx1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hmx1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa03367	NM_001113526.1 Latest version!	Danio rerio H6 family homeobox 1 (hmx1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

hmx1 ( NM_001113526.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001106998.1 Danio rerio H6 family homeobox 1 (hmx1), mRNA.

Price & Availability↑

CloneID	ODa03367
Clone ID Related Accession (Same CDS sequence)	NM_001113526.1
Accession Version	NM_001113526.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-20
Organism	Danio rerio(zebrafish)
Product	homeobox protein HMX1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EU050652.1. On Jan 17, 2008 this sequence version replaced XM_001334293.1. ##Evidence-Data-START## Transcript exon combination :: EU050652.1, EU203551.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168447, SAMEA3505370 [ECO:0000348] ##Evidence-Data-END##

ATGCATGAAA AAAGCCAGCA ACAGCACACT TCCACCACAT CCAGGGGCTC GTCGTTTTTT 
ATCGAGAATT TGCTTGGCTC TTGTAGGACA GAAAAGCCTG TCTGTCCAAT AAAGGATAAC 
GATGGCACGG AGAGAGCGAA TGCTCTCAAG CGCTACCCGA ACGCATATCG GAAAGAAATG 
TGCGTTCAAG CGTCCAGCGC GGGCTTCAAG ACGGAGATCT CGCCGCTGGA GTGGAAAGGA 
CGCGAAACCT CCAGGAGTCC AAGAGAGGAA AGCCGCAATT CCAGTGAATA TTCCCGCAGC 
GACAGAGACA CCCCTTTGGC CTCTGAGCCT CTTGATGGAG TAGTGGACCG AAAAATGAGC 
GGTTGTGCGG TTGACGAGGG TGACGACGCT CGACAGCTCT TCGATGAGCG TTCGGGGCCA 
GACACTTCCG AACCCGGCTC AGCCCGAAAG AAAAAGACCC GAACTGTGTT CAGCAGAAGC 
CAGGTTTTCC AGCTAGAGTC CACATTCGAC ATGAAGAGAT ACCTCAGCAG CTCTGAGCGC 
GCGGGGCTCG CGGCCTCCCT GCACCTGACC GAGACCCAGG TGAAAATCTG GTTTCAAAAC 
CGCCGAAACA AATGGAAAAG ACAACTGGCC GCGGATTTAG AGGCTGTTAA TTTTAACCAC 
AACTCTCAGC GGATTGTACG GGTGCCGATC TTGTACCACG ATAAAGCTAC ACCCATGTCG 
ACACTCAGTT TTAACGTGTC TCAAGTCTCG CCACCATTAA TGGGCTTTTC AAATTCAGTG 
AACTATCCAT TGTCGTCCTT TGCTCATTCA GTGAATTTAA TGACATCGCA GATGACAGGC 
CTTGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001106998.1
CDS	1..849
Translation	MHEKSQQQHTSTTSRGSSFFIENLLGSCRTEKPVCPIKDNDGTERANALKRYPNAYRKEMCVQASSAGFKTEISPLEWKGRETSRSPREESRNSSEYSRSDRDTPLASEPLDGVVDRKMSGCAVDEGDDARQLFDERSGPDTSEPGSARKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAADLEAVNFNHNSQRIVRVPILYHDKATPMSTLSFNVSQVSPPLMGFSNSVNYPLSSFAHSVNLMTSQMTGLV

Target ORF information:

RefSeq Version	NM_001113526.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio H6 family homeobox 1 (hmx1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001113526.1

ORF Insert Sequence:

ATGCATGAAA AAAGCCAGCA ACAGCACACT TCCACCACAT CCAGGGGCTC GTCGTTTTTT 
ATCGAGAATT TGCTTGGCTC TTGTAGGACA GAAAAGCCTG TCTGTCCAAT AAAGGATAAC 
GATGGCACGG AGAGAGCGAA TGCTCTCAAG CGCTACCCGA ACGCATATCG GAAAGAAATG 
TGCGTTCAAG CGTCCAGCGC GGGCTTCAAG ACGGAGATCT CGCCGCTGGA GTGGAAAGGA 
CGCGAAACCT CCAGGAGTCC AAGAGAGGAA AGCCGCAATT CCAGTGAATA TTCCCGCAGC 
GACAGAGACA CCCCTTTGGC CTCTGAGCCT CTTGATGGAG TAGTGGACCG AAAAATGAGC 
GGTTGTGCGG TTGACGAGGG TGACGACGCT CGACAGCTCT TCGATGAGCG TTCGGGGCCA 
GACACTTCCG AACCCGGCTC AGCCCGAAAG AAAAAGACCC GAACTGTGTT CAGCAGAAGC 
CAGGTTTTCC AGCTAGAGTC CACATTCGAC ATGAAGAGAT ACCTCAGCAG CTCTGAGCGC 
GCGGGGCTCG CGGCCTCCCT GCACCTGACC GAGACCCAGG TGAAAATCTG GTTTCAAAAC 
CGCCGAAACA AATGGAAAAG ACAACTGGCC GCGGATTTAG AGGCTGTTAA TTTTAACCAC 
AACTCTCAGC GGATTGTACG GGTGCCGATC TTGTACCACG ATAAAGCTAC ACCCATGTCG 
ACACTCAGTT TTAACGTGTC TCAAGTCTCG CCACCATTAA TGGGCTTTTC AAATTCAGTG 
AACTATCCAT TGTCGTCCTT TGCTCATTCA GTGAATTTAA TGACATCGCA GATGACAGGC 
CTTGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Xenopus laevis Nkx5.3 and sensory organ homeobox (SOHo) are expressed in developing sensory organs and ganglia of the head and anterior trunk.
Development genes and evolution226(6)423-428(2016 Nov)
Kelly LE,El-Hodiri HM

Genes and signaling networks regulated during zebrafish optic vesicle morphogenesis.
BMC genomics15825(2014 Sep)
Yin J,Morrissey ME,Shine L,Kennedy C,Higgins DG,Kennedy BN

A dimerized HMX1 inhibits EPHA6/epha4b in mouse and zebrafish retinas.
PloS one9(6)e100096(2014)
Marcelli F,Boisset G,Schorderet DF

Apoptotic and proliferative defects characterize ocular development in a microphthalmic BMP model.
Investigative ophthalmology & visual science54(7)4636-47(2013 Jul)
French CR,Stach TR,March LD,Lehmann OJ,Waskiewicz AJ