il2rb cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	il2rb
Entrez Gene ID	793920
Full Name	interleukin 2 receptor, beta
Synonyms	il-2rb
General protein information	Preferred Names interleukin 2 receptor, beta Names interleukin-2 receptor subunit beta
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005171592.3	XP_005171649.1	interleukin-2 receptor subunit beta isoform X1
NM_001128267.1	NP_001121739.1	interleukin-2 receptor subunit beta precursor
XM_005171592.4	XP_005171649.1	interleukin-2 receptor subunit beta isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	il2rb	NP_001121739.1
Gallus gallus (chicken)	LOC100859707	XP_003640434.2

Gene Ontology
Bibliography

Related articles in PubMed

Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing.
Tang Q, Iyer S, Lobbardi R, Moore JC, Chen H, Lareau C, Hebert C, Shaw ML, Neftel C, Suva ML, Ceol CJ, Bernards A, Aryee M, Pinello L, Drummond IA, Langenau DM
The Journal of experimental medicine214(10)2875-2887(2017 Oct)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Essential role of IL-4 and IL-4R? interaction in adaptive immunity of zebrafish: insight into the origin of Th2-like regulatory mechanism in ancient vertebrates.
Zhu LY, Pan PP, Fang W, Shao JZ, Xiang LX
Journal of immunology (Baltimore, Md. : 1950)188(11)5571-84(2012 Jun)

Two copies of the genes encoding the subunits of putative interleukin (IL)-4/IL-13 receptors, IL-4R?, IL-13R?1 and IL-13R?2, have been identified in rainbow trout (Oncorhynchus mykiss) and have complex patterns of expression and modulation.
Wang T, Huang W, Costa MM, Martin SA, Secombes CJ
Immunogenetics63(4)235-53(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following il2rb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the il2rb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa08234	NM_001128267.1 Latest version!	Danio rerio interleukin 2 receptor, beta (il2rb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
ODa08233	XM_005171592.4 Latest version!	Danio rerio interleukin 2 receptor, beta (il2rb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
View Old Accession Versions >>
ODa08233	XM_005171592.3	Danio rerio interleukin 2 receptor, beta (il2rb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

il2rb ( NM_001128267.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001121739.1 Danio rerio interleukin 2 receptor, beta (il2rb), mRNA.

Price & Availability↑

CloneID	ODa08234
Clone ID Related Accession (Same CDS sequence)	NM_001128267.1
Accession Version	NM_001128267.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	interleukin-2 receptor subunit beta precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BN000818.1. On Jul 31, 2008 this sequence version replaced XM_001922920.1. ##Evidence-Data-START## Transcript exon combination :: BN000818.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGAAGGATT ACTGGCGTTC CCTTCTGTTC ATCTTCATCA TACTTTGTGG AACCTGCCAG 
TCCAGCAACT CACAAACAGG AGATCTGACC TGTGTGAATG ACTACATGAC AAACATTTCT 
TGCGTGTGGT GGAACTATAG CAATTTCTCC AACCAGCAAT GTGAGCTTGA GGTTAACTGT 
AAAATAAGCA AAATGGTATT GTCTGTGAGC TGTAATGGAT CACTCATCAG CAGCCTGCAT 
TATAAGCCAG GCCGACACAT TAAGACGCAA CCACCAGATA AGCCTGTTGT GAATGGGAGC 
AACGTGTCTT GGAGTAAAGG CAGTAACTTT CCTAAATCCA TTAAGAAGCA TGAATTTCAA 
TTGCAGTTTA AAGATGCACA TACAAGCTGG GAGATGGCAA AACCCGGCCA ACTCTCTCAA 
GAAAACTACA CGCAGCTCAA CCATGATTTA CTGACTGTAG GAGAAGAATA CCAGGCCAGG 
GTGCGTGTGA AGCCAGTTGA GCCGAAAACT GACGGTCATT TTCGGGGGGA ATGGAGTGAA 
TGGAGTCCTG CCGTATCCTG GAGGTCTGAG ATTGGAAACC TACCAGTGAA ACCAAAAGAG 
GATTCACCCA AAAAGCGTGA TAATATGCCT GTAATTATGA TTGTTGGATT CAACCTACTG 
CTTGGTCTCA TTATCATACC AATAATCATC TATAAAGTAA AGAAAAGCAG CCGGCCATTA 
AAACCAATAC AACATGTTCC AGACCCATCC AAATACTTCC AGCCTCTTCA TACCATTCAT 
GGTGGAAACT TCCGGAAATG GCTGGGCGGT CAGAATTCAG TCGGCCCATT TCTTACGCCT 
CAATCCAGTG ATGACATCTC ACCCGTGGAG GTCTCCGATA TGTGGGACGT CTCCTTAATG 
GATCCCGATG CCCAGATGTC CACCACCATG CTAGTTCACG CCGGTCAGGT GGACTCTGGA 
GTGGAGAACA GCGGCACCAG TAAAGCATCG TCCTCCTCAG GTTTCTATAA CATGGGCTAC 
TTCTATAGCA AATCTCATAC TGGCTCACTC TACCTGGAAT CCTGTCCCGT GTATTTCTCT 
TACCACCCTG ATGAGGGCAC CCACTCTTCT CTCTCATCGT CCAGCTCTTC GTGCCACTCT 
TTGGGATCCC CAAGTTCCCT GCCGGAGCAG CCGATGAGCC CGGATTCAGG ATTTGCCATG 
TCTGATGAGC AGCATTGTGA GGATGATGGA GATGGTGAAG AGATAGGAGG CGCGGAGAGA 
GCAGTGGCAG AAGGAAAGGC ATTGGTTTCC TTCATTATGT CACTGTCTCA GGGTGGCGTT 
CAGCCGGCTG AGGTTTTCCC TCCAGTACCT GTCTTCTCAG CCTGGTCTGA ACTTGTAAAG 
GCGCCCAGCT GTGCTTCTCT CTGTGAGCCA GCAGAGAGCA CTGCACTCAG ACCTGCCTCC 
ATGATCGAGC CCAGCGGGAG CGGATATCTC ACCCTGAAGG AGATGCAGAA GTACAGCAAT 
AAATCCATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121739.1
CDS	1..1512
Translation	MKDYWRSLLFIFIILCGTCQSSNSQTGDLTCVNDYMTNISCVWWNYSNFSNQQCELEVNCKISKMVLSVSCNGSLISSLHYKPGRHIKTQPPDKPVVNGSNVSWSKGSNFPKSIKKHEFQLQFKDAHTSWEMAKPGQLSQENYTQLNHDLLTVGEEYQARVRVKPVEPKTDGHFRGEWSEWSPAVSWRSEIGNLPVKPKEDSPKKRDNMPVIMIVGFNLLLGLIIIPIIIYKVKKSSRPLKPIQHVPDPSKYFQPLHTIHGGNFRKWLGGQNSVGPFLTPQSSDDISPVEVSDMWDVSLMDPDAQMSTTMLVHAGQVDSGVENSGTSKASSSSGFYNMGYFYSKSHTGSLYLESCPVYFSYHPDEGTHSSLSSSSSSCHSLGSPSSLPEQPMSPDSGFAMSDEQHCEDDGDGEEIGGAERAVAEGKALVSFIMSLSQGGVQPAEVFPPVPVFSAWSELVKAPSCASLCEPAESTALRPASMIEPSGSGYLTLKEMQKYSNKSI

Target ORF information:

RefSeq Version	NM_001128267.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio interleukin 2 receptor, beta (il2rb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128267.1

ORF Insert Sequence:

ATGAAGGATT ACTGGCGTTC CCTTCTGTTC ATCTTCATCA TACTTTGTGG AACCTGCCAG 
TCCAGCAACT CACAAACAGG AGATCTGACC TGTGTGAATG ACTACATGAC AAACATTTCT 
TGCGTGTGGT GGAACTATAG CAATTTCTCC AACCAGCAAT GTGAGCTTGA GGTTAACTGT 
AAAATAAGCA AAATGGTATT GTCTGTGAGC TGTAATGGAT CACTCATCAG CAGCCTGCAT 
TATAAGCCAG GCCGACACAT TAAGACGCAA CCACCAGATA AGCCTGTTGT GAATGGGAGC 
AACGTGTCTT GGAGTAAAGG CAGTAACTTT CCTAAATCCA TTAAGAAGCA TGAATTTCAA 
TTGCAGTTTA AAGATGCACA TACAAGCTGG GAGATGGCAA AACCCGGCCA ACTCTCTCAA 
GAAAACTACA CGCAGCTCAA CCATGATTTA CTGACTGTAG GAGAAGAATA CCAGGCCAGG 
GTGCGTGTGA AGCCAGTTGA GCCGAAAACT GACGGTCATT TTCGGGGGGA ATGGAGTGAA 
TGGAGTCCTG CCGTATCCTG GAGGTCTGAG ATTGGAAACC TACCAGTGAA ACCAAAAGAG 
GATTCACCCA AAAAGCGTGA TAATATGCCT GTAATTATGA TTGTTGGATT CAACCTACTG 
CTTGGTCTCA TTATCATACC AATAATCATC TATAAAGTAA AGAAAAGCAG CCGGCCATTA 
AAACCAATAC AACATGTTCC AGACCCATCC AAATACTTCC AGCCTCTTCA TACCATTCAT 
GGTGGAAACT TCCGGAAATG GCTGGGCGGT CAGAATTCAG TCGGCCCATT TCTTACGCCT 
CAATCCAGTG ATGACATCTC ACCCGTGGAG GTCTCCGATA TGTGGGACGT CTCCTTAATG 
GATCCCGATG CCCAGATGTC CACCACCATG CTAGTTCACG CCGGTCAGGT GGACTCTGGA 
GTGGAGAACA GCGGCACCAG TAAAGCATCG TCCTCCTCAG GTTTCTATAA CATGGGCTAC 
TTCTATAGCA AATCTCATAC TGGCTCACTC TACCTGGAAT CCTGTCCCGT GTATTTCTCT 
TACCACCCTG ATGAGGGCAC CCACTCTTCT CTCTCATCGT CCAGCTCTTC GTGCCACTCT 
TTGGGATCCC CAAGTTCCCT GCCGGAGCAG CCGATGAGCC CGGATTCAGG ATTTGCCATG 
TCTGATGAGC AGCATTGTGA GGATGATGGA GATGGTGAAG AGATAGGAGG CGCGGAGAGA 
GCAGTGGCAG AAGGAAAGGC ATTGGTTTCC TTCATTATGT CACTGTCTCA GGGTGGCGTT 
CAGCCGGCTG AGGTTTTCCC TCCAGTACCT GTCTTCTCAG CCTGGTCTGA ACTTGTAAAG 
GCGCCCAGCT GTGCTTCTCT CTGTGAGCCA GCAGAGAGCA CTGCACTCAG ACCTGCCTCC 
ATGATCGAGC CCAGCGGGAG CGGATATCTC ACCCTGAAGG AGATGCAGAA GTACAGCAAT 
AAATCCATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

il2rb ( XM_005171592.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005171649.1 Danio rerio interleukin 2 receptor, beta (il2rb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa08233
Clone ID Related Accession (Same CDS sequence)	XM_005171592.3 , XM_005171592.4
Accession Version	XM_005171592.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1626bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-23
Organism	Danio rerio(Zebrafish)
Product	interleukin-2 receptor subunit beta isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007114.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_005171592.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGATT ACTGGCGTTC CCTTCTGTTC ATCTTCATCA TACTTTGTGG AACCTGCCAG 
TCCAGCAACT CACAAACAGG AGATCTGACC TGTGTGAATG ACTACATGAC AAACATTTCT 
TGCGTGTGGT GGAACTATAG CAATTTCTCC AACCAGCAAT GTGAGCTTGA GGTTAACTGT 
AAAATAAGTC CAAGCAGCCA ATCAAAATCT TCCAGATGTG AGCTGGTGCC GCAGAACAAC 
CTCTCAAATT CTCCCAGAAG CTGTTTTTTA TTTTGTGAAA ATGCTTACTT CTTTTTCCTT 
AGCAAAATGG TATTGTCTGT GAGCTGTAAT GGATCACTCA TCAGCAGCCT GCATTATAAG 
CCAGGCCGAC ACATTAAGAC GCAACCACCA GATAAGCCTG TTGTGAATGG GAGCAACGTG 
TCTTGGAGTA AAGGCAGTAA CTTTCCTAAA TCCATTAAGA AGCATGAATT TCAATTGCAG 
TTTAAAGATG CACATACAAG CTGGGAGATG GCAAAACCCG GCCAACTCTC TCAAGAAAAC 
TACACGCAGC TCAACCATGA TTTACTGACT GTAGGAGAAG AATACCAGGC CAGGGTGCGT 
GTGAAGCCAG TTGAGCCGAA AACTGACGGT CATTTTCGGG GGGAATGGAG TGAATGGAGT 
CCTGCCGTAT CCTGGAGGTC TGAGATTGGA AACCTACCAG TGAAACCAAA AGAGGATTCA 
CCCAAAAAGC GTGATAATAT GCCTGTAATT ATGATTGTTG GATTCAACCT ACTGCTTGGT 
CTCATTATCA TACCAATAAT CATCTATAAA GTAAAGAAAA GCAGCCGGCC ATTAAAACCA 
ATACAACATG TTCCAGACCC ATCCAAATAC TTCCAGCCTC TTCATACCAT TCATGGTGGA 
AACTTCCGGA AATGGCTGGG CGGTCAGAAT TCAGTCGGCC CATTTCTTAC GCCTCAATCC 
AGTGATGACA TCTCACCCGT GGAGGTCTCC GATATGTGGG ACGTCTCCTT AATGGATCCC 
GATGCCCAGA TGTCCACCAC CATGCTAGTT CACGCCGGTC AGGTGGACTC TGGAGTGGAG 
AACAGCGGCA CCAGTAAAGC ATCGTCCTCC TCAGGTTTCT ATAACATGGG CTACTTCTAT 
AGCAAATCTC ATACTGGCTC ACTCTACCTG GAATCCTGTC CCGTGTATTT CTCTTACCAC 
CCTGATGAGG GCACCCACTC TTCTCTCTCA TCGTCCAGCT CTTCGTGCCA CTCTTTGGGA 
TCCCCAAGTT CCCTGCCGGA GCAGCCGATG AGCCCGGATT CAGGATTTGC CATGTCTGAT 
GAGCAGCATT GTGAGGATGA TGGAGATGGT GAAGAGATAG GAGGCGCGGA GAGAGCAGTG 
GCAGAAGGAA AGGCATTGGT TTCCTTCATT ATGTCACTGT CTCAGGGTGG CGTTCAGCCG 
GCTGAGGTTT TCCCTCCAGT ACCTGTCTTC TCAGCCTGGT CTGAACTTGT AAAGGCGCCC 
AGCTGTGCTT CTCTCTGTGA GCCAGCAGAG AGCACTGCAC TCAGACCTGC CTCCATGATC 
GAGCCCAGCG GGAGCGGATA TCTCACCCTG AAGGAGATGC AGAAGTACAG CAATAAATCC 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005171649.1
CDS	185..1810
Translation	MKDYWRSLLFIFIILCGTCQSSNSQTGDLTCVNDYMTNISCVWWNYSNFSNQQCELEVNCKISPSSQSKSSRCELVPQNNLSNSPRSCFLFCENAYFFFLSKMVLSVSCNGSLISSLHYKPGRHIKTQPPDKPVVNGSNVSWSKGSNFPKSIKKHEFQLQFKDAHTSWEMAKPGQLSQENYTQLNHDLLTVGEEYQARVRVKPVEPKTDGHFRGEWSEWSPAVSWRSEIGNLPVKPKEDSPKKRDNMPVIMIVGFNLLLGLIIIPIIIYKVKKSSRPLKPIQHVPDPSKYFQPLHTIHGGNFRKWLGGQNSVGPFLTPQSSDDISPVEVSDMWDVSLMDPDAQMSTTMLVHAGQVDSGVENSGTSKASSSSGFYNMGYFYSKSHTGSLYLESCPVYFSYHPDEGTHSSLSSSSSSCHSLGSPSSLPEQPMSPDSGFAMSDEQHCEDDGDGEEIGGAERAVAEGKALVSFIMSLSQGGVQPAEVFPPVPVFSAWSELVKAPSCASLCEPAESTALRPASMIEPSGSGYLTLKEMQKYSNKSI

Target ORF information:

RefSeq Version	XM_005171592.3
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio interleukin 2 receptor, beta (il2rb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005171592.3

ORF Insert Sequence:

ATGAAGGATT ACTGGCGTTC CCTTCTGTTC ATCTTCATCA TACTTTGTGG AACCTGCCAG 
TCCAGCAACT CACAAACAGG AGATCTGACC TGTGTGAATG ACTACATGAC AAACATTTCT 
TGCGTGTGGT GGAACTATAG CAATTTCTCC AACCAGCAAT GTGAGCTTGA GGTTAACTGT 
AAAATAAGTC CAAGCAGCCA ATCAAAATCT TCCAGATGTG AGCTGGTGCC GCAGAACAAC 
CTCTCAAATT CTCCCAGAAG CTGTTTTTTA TTTTGTGAAA ATGCTTACTT CTTTTTCCTT 
AGCAAAATGG TATTGTCTGT GAGCTGTAAT GGATCACTCA TCAGCAGCCT GCATTATAAG 
CCAGGCCGAC ACATTAAGAC GCAACCACCA GATAAGCCTG TTGTGAATGG GAGCAACGTG 
TCTTGGAGTA AAGGCAGTAA CTTTCCTAAA TCCATTAAGA AGCATGAATT TCAATTGCAG 
TTTAAAGATG CACATACAAG CTGGGAGATG GCAAAACCCG GCCAACTCTC TCAAGAAAAC 
TACACGCAGC TCAACCATGA TTTACTGACT GTAGGAGAAG AATACCAGGC CAGGGTGCGT 
GTGAAGCCAG TTGAGCCGAA AACTGACGGT CATTTTCGGG GGGAATGGAG TGAATGGAGT 
CCTGCCGTAT CCTGGAGGTC TGAGATTGGA AACCTACCAG TGAAACCAAA AGAGGATTCA 
CCCAAAAAGC GTGATAATAT GCCTGTAATT ATGATTGTTG GATTCAACCT ACTGCTTGGT 
CTCATTATCA TACCAATAAT CATCTATAAA GTAAAGAAAA GCAGCCGGCC ATTAAAACCA 
ATACAACATG TTCCAGACCC ATCCAAATAC TTCCAGCCTC TTCATACCAT TCATGGTGGA 
AACTTCCGGA AATGGCTGGG CGGTCAGAAT TCAGTCGGCC CATTTCTTAC GCCTCAATCC 
AGTGATGACA TCTCACCCGT GGAGGTCTCC GATATGTGGG ACGTCTCCTT AATGGATCCC 
GATGCCCAGA TGTCCACCAC CATGCTAGTT CACGCCGGTC AGGTGGACTC TGGAGTGGAG 
AACAGCGGCA CCAGTAAAGC ATCGTCCTCC TCAGGTTTCT ATAACATGGG CTACTTCTAT 
AGCAAATCTC ATACTGGCTC ACTCTACCTG GAATCCTGTC CCGTGTATTT CTCTTACCAC 
CCTGATGAGG GCACCCACTC TTCTCTCTCA TCGTCCAGCT CTTCGTGCCA CTCTTTGGGA 
TCCCCAAGTT CCCTGCCGGA GCAGCCGATG AGCCCGGATT CAGGATTTGC CATGTCTGAT 
GAGCAGCATT GTGAGGATGA TGGAGATGGT GAAGAGATAG GAGGCGCGGA GAGAGCAGTG 
GCAGAAGGAA AGGCATTGGT TTCCTTCATT ATGTCACTGT CTCAGGGTGG CGTTCAGCCG 
GCTGAGGTTT TCCCTCCAGT ACCTGTCTTC TCAGCCTGGT CTGAACTTGT AAAGGCGCCC 
AGCTGTGCTT CTCTCTGTGA GCCAGCAGAG AGCACTGCAC TCAGACCTGC CTCCATGATC 
GAGCCCAGCG GGAGCGGATA TCTCACCCTG AAGGAGATGC AGAAGTACAG CAATAAATCC 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

il2rb ( XM_005171592.4 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005171649.1 Danio rerio interleukin 2 receptor, beta (il2rb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa08233
Clone ID Related Accession (Same CDS sequence)	XM_005171592.3 , XM_005171592.4
Accession Version	XM_005171592.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1626bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-14
Organism	Danio rerio(zebrafish)
Product	interleukin-2 receptor subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007114.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XM_005171592.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGATT ACTGGCGTTC CCTTCTGTTC ATCTTCATCA TACTTTGTGG AACCTGCCAG 
TCCAGCAACT CACAAACAGG AGATCTGACC TGTGTGAATG ACTACATGAC AAACATTTCT 
TGCGTGTGGT GGAACTATAG CAATTTCTCC AACCAGCAAT GTGAGCTTGA GGTTAACTGT 
AAAATAAGTC CAAGCAGCCA ATCAAAATCT TCCAGATGTG AGCTGGTGCC GCAGAACAAC 
CTCTCAAATT CTCCCAGAAG CTGTTTTTTA TTTTGTGAAA ATGCTTACTT CTTTTTCCTT 
AGCAAAATGG TATTGTCTGT GAGCTGTAAT GGATCACTCA TCAGCAGCCT GCATTATAAG 
CCAGGCCGAC ACATTAAGAC GCAACCACCA GATAAGCCTG TTGTGAATGG GAGCAACGTG 
TCTTGGAGTA AAGGCAGTAA CTTTCCTAAA TCCATTAAGA AGCATGAATT TCAATTGCAG 
TTTAAAGATG CACATACAAG CTGGGAGATG GCAAAACCCG GCCAACTCTC TCAAGAAAAC 
TACACGCAGC TCAACCATGA TTTACTGACT GTAGGAGAAG AATACCAGGC CAGGGTGCGT 
GTGAAGCCAG TTGAGCCGAA AACTGACGGT CATTTTCGGG GGGAATGGAG TGAATGGAGT 
CCTGCCGTAT CCTGGAGGTC TGAGATTGGA AACCTACCAG TGAAACCAAA AGAGGATTCA 
CCCAAAAAGC GTGATAATAT GCCTGTAATT ATGATTGTTG GATTCAACCT ACTGCTTGGT 
CTCATTATCA TACCAATAAT CATCTATAAA GTAAAGAAAA GCAGCCGGCC ATTAAAACCA 
ATACAACATG TTCCAGACCC ATCCAAATAC TTCCAGCCTC TTCATACCAT TCATGGTGGA 
AACTTCCGGA AATGGCTGGG CGGTCAGAAT TCAGTCGGCC CATTTCTTAC GCCTCAATCC 
AGTGATGACA TCTCACCCGT GGAGGTCTCC GATATGTGGG ACGTCTCCTT AATGGATCCC 
GATGCCCAGA TGTCCACCAC CATGCTAGTT CACGCCGGTC AGGTGGACTC TGGAGTGGAG 
AACAGCGGCA CCAGTAAAGC ATCGTCCTCC TCAGGTTTCT ATAACATGGG CTACTTCTAT 
AGCAAATCTC ATACTGGCTC ACTCTACCTG GAATCCTGTC CCGTGTATTT CTCTTACCAC 
CCTGATGAGG GCACCCACTC TTCTCTCTCA TCGTCCAGCT CTTCGTGCCA CTCTTTGGGA 
TCCCCAAGTT CCCTGCCGGA GCAGCCGATG AGCCCGGATT CAGGATTTGC CATGTCTGAT 
GAGCAGCATT GTGAGGATGA TGGAGATGGT GAAGAGATAG GAGGCGCGGA GAGAGCAGTG 
GCAGAAGGAA AGGCATTGGT TTCCTTCATT ATGTCACTGT CTCAGGGTGG CGTTCAGCCG 
GCTGAGGTTT TCCCTCCAGT ACCTGTCTTC TCAGCCTGGT CTGAACTTGT AAAGGCGCCC 
AGCTGTGCTT CTCTCTGTGA GCCAGCAGAG AGCACTGCAC TCAGACCTGC CTCCATGATC 
GAGCCCAGCG GGAGCGGATA TCTCACCCTG AAGGAGATGC AGAAGTACAG CAATAAATCC 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005171649.1
CDS	635..2260
Translation	MKDYWRSLLFIFIILCGTCQSSNSQTGDLTCVNDYMTNISCVWWNYSNFSNQQCELEVNCKISPSSQSKSSRCELVPQNNLSNSPRSCFLFCENAYFFFLSKMVLSVSCNGSLISSLHYKPGRHIKTQPPDKPVVNGSNVSWSKGSNFPKSIKKHEFQLQFKDAHTSWEMAKPGQLSQENYTQLNHDLLTVGEEYQARVRVKPVEPKTDGHFRGEWSEWSPAVSWRSEIGNLPVKPKEDSPKKRDNMPVIMIVGFNLLLGLIIIPIIIYKVKKSSRPLKPIQHVPDPSKYFQPLHTIHGGNFRKWLGGQNSVGPFLTPQSSDDISPVEVSDMWDVSLMDPDAQMSTTMLVHAGQVDSGVENSGTSKASSSSGFYNMGYFYSKSHTGSLYLESCPVYFSYHPDEGTHSSLSSSSSSCHSLGSPSSLPEQPMSPDSGFAMSDEQHCEDDGDGEEIGGAERAVAEGKALVSFIMSLSQGGVQPAEVFPPVPVFSAWSELVKAPSCASLCEPAESTALRPASMIEPSGSGYLTLKEMQKYSNKSI

Target ORF information:

RefSeq Version	XM_005171592.4
Organism	Danio rerio(zebrafish)
Definition	Danio rerio interleukin 2 receptor, beta (il2rb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005171592.4

ORF Insert Sequence:

ATGAAGGATT ACTGGCGTTC CCTTCTGTTC ATCTTCATCA TACTTTGTGG AACCTGCCAG 
TCCAGCAACT CACAAACAGG AGATCTGACC TGTGTGAATG ACTACATGAC AAACATTTCT 
TGCGTGTGGT GGAACTATAG CAATTTCTCC AACCAGCAAT GTGAGCTTGA GGTTAACTGT 
AAAATAAGTC CAAGCAGCCA ATCAAAATCT TCCAGATGTG AGCTGGTGCC GCAGAACAAC 
CTCTCAAATT CTCCCAGAAG CTGTTTTTTA TTTTGTGAAA ATGCTTACTT CTTTTTCCTT 
AGCAAAATGG TATTGTCTGT GAGCTGTAAT GGATCACTCA TCAGCAGCCT GCATTATAAG 
CCAGGCCGAC ACATTAAGAC GCAACCACCA GATAAGCCTG TTGTGAATGG GAGCAACGTG 
TCTTGGAGTA AAGGCAGTAA CTTTCCTAAA TCCATTAAGA AGCATGAATT TCAATTGCAG 
TTTAAAGATG CACATACAAG CTGGGAGATG GCAAAACCCG GCCAACTCTC TCAAGAAAAC 
TACACGCAGC TCAACCATGA TTTACTGACT GTAGGAGAAG AATACCAGGC CAGGGTGCGT 
GTGAAGCCAG TTGAGCCGAA AACTGACGGT CATTTTCGGG GGGAATGGAG TGAATGGAGT 
CCTGCCGTAT CCTGGAGGTC TGAGATTGGA AACCTACCAG TGAAACCAAA AGAGGATTCA 
CCCAAAAAGC GTGATAATAT GCCTGTAATT ATGATTGTTG GATTCAACCT ACTGCTTGGT 
CTCATTATCA TACCAATAAT CATCTATAAA GTAAAGAAAA GCAGCCGGCC ATTAAAACCA 
ATACAACATG TTCCAGACCC ATCCAAATAC TTCCAGCCTC TTCATACCAT TCATGGTGGA 
AACTTCCGGA AATGGCTGGG CGGTCAGAAT TCAGTCGGCC CATTTCTTAC GCCTCAATCC 
AGTGATGACA TCTCACCCGT GGAGGTCTCC GATATGTGGG ACGTCTCCTT AATGGATCCC 
GATGCCCAGA TGTCCACCAC CATGCTAGTT CACGCCGGTC AGGTGGACTC TGGAGTGGAG 
AACAGCGGCA CCAGTAAAGC ATCGTCCTCC TCAGGTTTCT ATAACATGGG CTACTTCTAT 
AGCAAATCTC ATACTGGCTC ACTCTACCTG GAATCCTGTC CCGTGTATTT CTCTTACCAC 
CCTGATGAGG GCACCCACTC TTCTCTCTCA TCGTCCAGCT CTTCGTGCCA CTCTTTGGGA 
TCCCCAAGTT CCCTGCCGGA GCAGCCGATG AGCCCGGATT CAGGATTTGC CATGTCTGAT 
GAGCAGCATT GTGAGGATGA TGGAGATGGT GAAGAGATAG GAGGCGCGGA GAGAGCAGTG 
GCAGAAGGAA AGGCATTGGT TTCCTTCATT ATGTCACTGT CTCAGGGTGG CGTTCAGCCG 
GCTGAGGTTT TCCCTCCAGT ACCTGTCTTC TCAGCCTGGT CTGAACTTGT AAAGGCGCCC 
AGCTGTGCTT CTCTCTGTGA GCCAGCAGAG AGCACTGCAC TCAGACCTGC CTCCATGATC 
GAGCCCAGCG GGAGCGGATA TCTCACCCTG AAGGAGATGC AGAAGTACAG CAATAAATCC 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing.
The Journal of experimental medicine214(10)2875-2887(2017 Oct)
Tang Q,Iyer S,Lobbardi R,Moore JC,Chen H,Lareau C,Hebert C,Shaw ML,Neftel C,Suva ML,Ceol CJ,Bernards A,Aryee M,Pinello L,Drummond IA,Langenau DM

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Essential role of IL-4 and IL-4R? interaction in adaptive immunity of zebrafish: insight into the origin of Th2-like regulatory mechanism in ancient vertebrates.
Journal of immunology (Baltimore, Md. : 1950)188(11)5571-84(2012 Jun)
Zhu LY,Pan PP,Fang W,Shao JZ,Xiang LX

Two copies of the genes encoding the subunits of putative interleukin (IL)-4/IL-13 receptors, IL-4R?, IL-13R?1 and IL-13R?2, have been identified in rainbow trout (Oncorhynchus mykiss) and have complex patterns of expression and modulation.
Immunogenetics63(4)235-53(2011 Apr)
Wang T,Huang W,Costa MM,Martin SA,Secombes CJ