irf1a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	irf1a
Entrez Gene ID	678604
Full Name	interferon regulatory factor 1a
Synonyms	IRF11,irf1,zgc:136945
General protein information	Preferred Names interferon regulatory factor 1a Names interferon regulatory factor 1a interferon regulatory factor 1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_009307024.2	XP_009305299.1	interferon regulatory factor 1a isoform X1
XM_009307024.3	XP_009305299.1	interferon regulatory factor 1a isoform X1
NM_001040352.1	NP_001035442.1	interferon regulatory factor 1a

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Metagenomics analysis of gut microbiota and immune modulation in zebrafish (Danio rerio) fed chitosan silver nanocomposites.
Udayangani RMC, Dananjaya SHS, Nikapitiya C, Heo GJ, Lee J, De Zoysa M
Fish & shellfish immunology66173-184(2017 Jul)

Two type II IFN members, IFN-? and IFN-? related (rel), regulate differentially IRF1 and IRF11 in zebrafish.
Ruan BY, Chen SN, Hou J, Huang B, Laghari ZA, Li L, Nie P
Fish & shellfish immunology65103-110(2017 Jun)

Zebrafish STAT6 negatively regulates IFN?1 production by attenuating the kinase activity of TANK-binding kinase 1.
Li S, Lu LF, LaPatra SE, Chen DD, Zhang YA
Developmental and comparative immunology67189-201(2017 Feb)

Chronic alcohol exposure induces muscle atrophy (myopathy) in zebrafish and alters the expression of microRNAs targeting the Notch pathway in skeletal muscle.
Khayrullin A, Smith L, Mistry D, Dukes A, Pan YA, Hamrick MW
Biochemical and biophysical research communications479(3)590-595(2016 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Following spring viremia of carp virus infection, DrIFNPhi1/3 and DrIRF1/3/7 transcripts are significantly induced in zebrafish tissues, which correlates with the replication of spring viremia of carp virus. data provide evidence that fish and mammals have evolved a similar IRF-dependent regulatory mechanism fine-tuning IFN gene activation.
Title: Zebrafish IRF1, IRF3, and IRF7 Differentially Regulate IFN?1 and IFN?3 Expression through Assembly of Homo- or Heteroprotein Complexes.

The following irf1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the irf1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa38545	NM_001040352.1 Latest version!	Danio rerio interferon regulatory factor 1a (irf1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
ODa46425	XM_009307024.3 Latest version!	Danio rerio interferon regulatory factor 1a (irf1a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
View Old Accession Versions >>
ODa46425	XM_009307024.2	Danio rerio interferon regulatory factor 1a (irf1a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

irf1a ( NM_001040352.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001035442.1 Danio rerio interferon regulatory factor 1a (irf1a), mRNA.

Price & Availability↑

CloneID	ODa38545
Clone ID Related Accession (Same CDS sequence)	NM_001040352.1
Accession Version	NM_001040352.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 756bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-17
Organism	Danio rerio(zebrafish)
Product	interferon regulatory factor 1a
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC115340.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC115340.1, BC067605.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGCATCAGG GGCGTCTGCG CTTACGGCCC TGGCTGGAGG AACAGATCCA GTCCGGCAGA 
TACCCGGGAG TCCAGTGGCT GGACCAGTCG GCCAGAGTTT TCCAGATCCC CTGGAAACAT 
GCAGCGAGAC ACGGCTGGAA CATCGACAAG GACGCAACAC TGTTCAGGAA CTGGGCCATT 
CACACAGGCA GATATAAGCC TGGAATAGAC AAACCGGATC CTAAAACGTG GAAGGCGAAC 
TTCAGATGCG CTCTCAATTC CCTGACCGAC GTCAAAGAGC TGCAGGACAG AAGCATCAAG 
AAAGGCCACA ACGCCTTCAG GGTGTACGCG CTGCTGCCGC ACTGCAAAAC CATCAGGAGA 
CGCAAAGCAG CGTTACGGTA TTCAGACACA GACAGTAAAG AAGCTTCACC TGCAGCACAA 
ACACAGAGAA ACTCCCTGGA GAGATTCACA GAGGCCTTCT GGAAGTTTCC AGATGACCGA 
GGAGCGTCTG CTGGACTGAT GAAGGACTCA GAGGAGGAGC GAGCGCAGGG ACTGCAGATC 
AACAGAACAG ACGAACACGA GCAGACAGAA GCAGTGCTGA AGATTGTGGA TCATCTGAAG 
ACTCTGGATC ACTGGGCTTC CTCATATGAC GGCGAGCGAG GCTGGAGACC CAACTCCACA 
TGGACGGGGT GCCTGGGGGA GACGGTGGAC TTTCCAGCAT TCTCCTTCCA GACTGACTGT 
AATCTTCACA CTATTTCACC AGCACAGTAT GACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035442.1
CDS	124..879
Translation	MHQGRLRLRPWLEEQIQSGRYPGVQWLDQSARVFQIPWKHAARHGWNIDKDATLFRNWAIHTGRYKPGIDKPDPKTWKANFRCALNSLTDVKELQDRSIKKGHNAFRVYALLPHCKTIRRRKAALRYSDTDSKEASPAAQTQRNSLERFTEAFWKFPDDRGASAGLMKDSEEERAQGLQINRTDEHEQTEAVLKIVDHLKTLDHWASSYDGERGWRPNSTWTGCLGETVDFPAFSFQTDCNLHTISPAQYD

Target ORF information:

RefSeq Version	NM_001040352.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio interferon regulatory factor 1a (irf1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040352.1

ORF Insert Sequence:

ATGCATCAGG GGCGTCTGCG CTTACGGCCC TGGCTGGAGG AACAGATCCA GTCCGGCAGA 
TACCCGGGAG TCCAGTGGCT GGACCAGTCG GCCAGAGTTT TCCAGATCCC CTGGAAACAT 
GCAGCGAGAC ACGGCTGGAA CATCGACAAG GACGCAACAC TGTTCAGGAA CTGGGCCATT 
CACACAGGCA GATATAAGCC TGGAATAGAC AAACCGGATC CTAAAACGTG GAAGGCGAAC 
TTCAGATGCG CTCTCAATTC CCTGACCGAC GTCAAAGAGC TGCAGGACAG AAGCATCAAG 
AAAGGCCACA ACGCCTTCAG GGTGTACGCG CTGCTGCCGC ACTGCAAAAC CATCAGGAGA 
CGCAAAGCAG CGTTACGGTA TTCAGACACA GACAGTAAAG AAGCTTCACC TGCAGCACAA 
ACACAGAGAA ACTCCCTGGA GAGATTCACA GAGGCCTTCT GGAAGTTTCC AGATGACCGA 
GGAGCGTCTG CTGGACTGAT GAAGGACTCA GAGGAGGAGC GAGCGCAGGG ACTGCAGATC 
AACAGAACAG ACGAACACGA GCAGACAGAA GCAGTGCTGA AGATTGTGGA TCATCTGAAG 
ACTCTGGATC ACTGGGCTTC CTCATATGAC GGCGAGCGAG GCTGGAGACC CAACTCCACA 
TGGACGGGGT GCCTGGGGGA GACGGTGGAC TTTCCAGCAT TCTCCTTCCA GACTGACTGT 
AATCTTCACA CTATTTCACC AGCACAGTAT GACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

irf1a ( XM_009307024.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_009305299.1 Danio rerio interferon regulatory factor 1a (irf1a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa46425
Clone ID Related Accession (Same CDS sequence)	XM_009307024.2 , XM_009307024.3
Accession Version	XM_009307024.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-23
Organism	Danio rerio(Zebrafish)
Product	interferon regulatory factor 1a isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007124.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_009307024.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATCAGG GGCGTCTGCG CTTACGGCCC TGGCTGGAGG AACAGATCCA GTCCGGCAGA 
TACCCGGGAG TCCAGTGGCT GGACCAGTCG GCCAGAGTTT TCCAGATCCC CTGGAAACAT 
GCAGCGAGAC ACGGCTGGAA CATTGACAAG GACGCAACAC TGTTCAGGAA CTGGGCCATT 
CACACAGGCA GATATAAGCC TGGAATAGAC AAACCGGATC CTAAAACGTG GAAGGCGAAC 
TTCAGATGCG CTCTCAATTC CCTGACCGAC GTCAAAGAGC TGCAGGACAG AAGCATCAAG 
AAAGGCCACA ACGCCTTCAG GGTGTACGCG CTGCTGCCGC ACTGCAAAAC CATCAGGAGA 
CGCAAAGCGT TACGGTATTC AGACACAGAC AGTAAAGAAG CTTCACCTGC AGCACAAACA 
CAGAGAAACT CCCTGGAGAG ATTCACAGAG GCCTTCTGGA AGTTTCCAGA TGACAGAGGA 
GCGTCTGCTG GACTGATGAA GGACTCAGAG GAGGAGCGAG CGCAGGGACT GCAGATCAAC 
AGAACAGACG AACACGAGCA GACAGAAGCA GTGCTGAAGA TTGTGGATCA TCTGAAGACT 
CTGGATCACT GGGCTTCCTC ATATGACGGC GAGCGAGGCT GGAGACCCAA CTCCACATGG 
ACGGGGTGCC TGGGAGAGAC GGTGGACTTT CCAGGATTCT CCTTTCAGAC TGACTGTAAT 
CTTCACACTA TTTCACCAGC ACAGTATGAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009305299.1
CDS	150..902
Translation	MHQGRLRLRPWLEEQIQSGRYPGVQWLDQSARVFQIPWKHAARHGWNIDKDATLFRNWAIHTGRYKPGIDKPDPKTWKANFRCALNSLTDVKELQDRSIKKGHNAFRVYALLPHCKTIRRRKALRYSDTDSKEASPAAQTQRNSLERFTEAFWKFPDDRGASAGLMKDSEEERAQGLQINRTDEHEQTEAVLKIVDHLKTLDHWASSYDGERGWRPNSTWTGCLGETVDFPGFSFQTDCNLHTISPAQYD

Target ORF information:

RefSeq Version	XM_009307024.2
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio interferon regulatory factor 1a (irf1a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009307024.2

ORF Insert Sequence:

ATGCATCAGG GGCGTCTGCG CTTACGGCCC TGGCTGGAGG AACAGATCCA GTCCGGCAGA 
TACCCGGGAG TCCAGTGGCT GGACCAGTCG GCCAGAGTTT TCCAGATCCC CTGGAAACAT 
GCAGCGAGAC ACGGCTGGAA CATTGACAAG GACGCAACAC TGTTCAGGAA CTGGGCCATT 
CACACAGGCA GATATAAGCC TGGAATAGAC AAACCGGATC CTAAAACGTG GAAGGCGAAC 
TTCAGATGCG CTCTCAATTC CCTGACCGAC GTCAAAGAGC TGCAGGACAG AAGCATCAAG 
AAAGGCCACA ACGCCTTCAG GGTGTACGCG CTGCTGCCGC ACTGCAAAAC CATCAGGAGA 
CGCAAAGCGT TACGGTATTC AGACACAGAC AGTAAAGAAG CTTCACCTGC AGCACAAACA 
CAGAGAAACT CCCTGGAGAG ATTCACAGAG GCCTTCTGGA AGTTTCCAGA TGACAGAGGA 
GCGTCTGCTG GACTGATGAA GGACTCAGAG GAGGAGCGAG CGCAGGGACT GCAGATCAAC 
AGAACAGACG AACACGAGCA GACAGAAGCA GTGCTGAAGA TTGTGGATCA TCTGAAGACT 
CTGGATCACT GGGCTTCCTC ATATGACGGC GAGCGAGGCT GGAGACCCAA CTCCACATGG 
ACGGGGTGCC TGGGAGAGAC GGTGGACTTT CCAGGATTCT CCTTTCAGAC TGACTGTAAT 
CTTCACACTA TTTCACCAGC ACAGTATGAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

irf1a ( XM_009307024.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_009305299.1 Danio rerio interferon regulatory factor 1a (irf1a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa46425
Clone ID Related Accession (Same CDS sequence)	XM_009307024.2 , XM_009307024.3
Accession Version	XM_009307024.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-14
Organism	Danio rerio(zebrafish)
Product	interferon regulatory factor 1a isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007124.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XM_009307024.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATCAGG GGCGTCTGCG CTTACGGCCC TGGCTGGAGG AACAGATCCA GTCCGGCAGA 
TACCCGGGAG TCCAGTGGCT GGACCAGTCG GCCAGAGTTT TCCAGATCCC CTGGAAACAT 
GCAGCGAGAC ACGGCTGGAA CATTGACAAG GACGCAACAC TGTTCAGGAA CTGGGCCATT 
CACACAGGCA GATATAAGCC TGGAATAGAC AAACCGGATC CTAAAACGTG GAAGGCGAAC 
TTCAGATGCG CTCTCAATTC CCTGACCGAC GTCAAAGAGC TGCAGGACAG AAGCATCAAG 
AAAGGCCACA ACGCCTTCAG GGTGTACGCG CTGCTGCCGC ACTGCAAAAC CATCAGGAGA 
CGCAAAGCGT TACGGTATTC AGACACAGAC AGTAAAGAAG CTTCACCTGC AGCACAAACA 
CAGAGAAACT CCCTGGAGAG ATTCACAGAG GCCTTCTGGA AGTTTCCAGA TGACAGAGGA 
GCGTCTGCTG GACTGATGAA GGACTCAGAG GAGGAGCGAG CGCAGGGACT GCAGATCAAC 
AGAACAGACG AACACGAGCA GACAGAAGCA GTGCTGAAGA TTGTGGATCA TCTGAAGACT 
CTGGATCACT GGGCTTCCTC ATATGACGGC GAGCGAGGCT GGAGACCCAA CTCCACATGG 
ACGGGGTGCC TGGGAGAGAC GGTGGACTTT CCAGGATTCT CCTTTCAGAC TGACTGTAAT 
CTTCACACTA TTTCACCAGC ACAGTATGAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009305299.1
CDS	138..890
Translation	MHQGRLRLRPWLEEQIQSGRYPGVQWLDQSARVFQIPWKHAARHGWNIDKDATLFRNWAIHTGRYKPGIDKPDPKTWKANFRCALNSLTDVKELQDRSIKKGHNAFRVYALLPHCKTIRRRKALRYSDTDSKEASPAAQTQRNSLERFTEAFWKFPDDRGASAGLMKDSEEERAQGLQINRTDEHEQTEAVLKIVDHLKTLDHWASSYDGERGWRPNSTWTGCLGETVDFPGFSFQTDCNLHTISPAQYD

Target ORF information:

RefSeq Version	XM_009307024.3
Organism	Danio rerio(zebrafish)
Definition	Danio rerio interferon regulatory factor 1a (irf1a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009307024.3

ORF Insert Sequence:

ATGCATCAGG GGCGTCTGCG CTTACGGCCC TGGCTGGAGG AACAGATCCA GTCCGGCAGA 
TACCCGGGAG TCCAGTGGCT GGACCAGTCG GCCAGAGTTT TCCAGATCCC CTGGAAACAT 
GCAGCGAGAC ACGGCTGGAA CATTGACAAG GACGCAACAC TGTTCAGGAA CTGGGCCATT 
CACACAGGCA GATATAAGCC TGGAATAGAC AAACCGGATC CTAAAACGTG GAAGGCGAAC 
TTCAGATGCG CTCTCAATTC CCTGACCGAC GTCAAAGAGC TGCAGGACAG AAGCATCAAG 
AAAGGCCACA ACGCCTTCAG GGTGTACGCG CTGCTGCCGC ACTGCAAAAC CATCAGGAGA 
CGCAAAGCGT TACGGTATTC AGACACAGAC AGTAAAGAAG CTTCACCTGC AGCACAAACA 
CAGAGAAACT CCCTGGAGAG ATTCACAGAG GCCTTCTGGA AGTTTCCAGA TGACAGAGGA 
GCGTCTGCTG GACTGATGAA GGACTCAGAG GAGGAGCGAG CGCAGGGACT GCAGATCAAC 
AGAACAGACG AACACGAGCA GACAGAAGCA GTGCTGAAGA TTGTGGATCA TCTGAAGACT 
CTGGATCACT GGGCTTCCTC ATATGACGGC GAGCGAGGCT GGAGACCCAA CTCCACATGG 
ACGGGGTGCC TGGGAGAGAC GGTGGACTTT CCAGGATTCT CCTTTCAGAC TGACTGTAAT 
CTTCACACTA TTTCACCAGC ACAGTATGAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Metagenomics analysis of gut microbiota and immune modulation in zebrafish (Danio rerio) fed chitosan silver nanocomposites.
Fish & shellfish immunology66173-184(2017 Jul)
Udayangani RMC,Dananjaya SHS,Nikapitiya C,Heo GJ,Lee J,De Zoysa M

Two type II IFN members, IFN-? and IFN-? related (rel), regulate differentially IRF1 and IRF11 in zebrafish.
Fish & shellfish immunology65103-110(2017 Jun)
Ruan BY,Chen SN,Hou J,Huang B,Laghari ZA,Li L,Nie P

Zebrafish STAT6 negatively regulates IFN?1 production by attenuating the kinase activity of TANK-binding kinase 1.
Developmental and comparative immunology67189-201(2017 Feb)
Li S,Lu LF,LaPatra SE,Chen DD,Zhang YA

Chronic alcohol exposure induces muscle atrophy (myopathy) in zebrafish and alters the expression of microRNAs targeting the Notch pathway in skeletal muscle.
Biochemical and biophysical research communications479(3)590-595(2016 Oct)
Khayrullin A,Smith L,Mistry D,Dukes A,Pan YA,Hamrick MW