ccdc151 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ccdc151
Entrez Gene ID	555601
Full Name	coiled-coil domain containing 151
Synonyms	zgc:152917
General protein information	Preferred Names coiled-coil domain containing 151 Names coiled-coil domain-containing protein 151 flanders unm ts272 unm_ts272
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001077369.2	NP_001070837.2	coiled-coil domain-containing protein 151

Pathways from BioSystems

Homologies

	CCDC151	XP_001106119.2
Canis lupus familiaris (dog)	CCDC151	XP_005632912.1
Bos taurus (cattle)	CCDC151	NP_001095517.1
Xenopus tropicalis (tropical clawed frog)	ccdc151	XP_004918954.1
Mus musculus (house mouse)	Ccdc151	NP_001157259.1
Danio rerio (zebrafish)	ccdc151	NP_001070837.2
Homo sapiens (human)	CCDC151	NP_659482.3
Pan troglodytes (chimpanzee)	CCDC151	XP_003316123.1
Rattus norvegicus (Norway rat)	Ccdc151	XP_006242749.1

Gene Ontology
Bibliography

Related articles in PubMed

Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature.
Grimes DT, Boswell CW, Morante NF, Henkelman RM, Burdine RD, Ciruna B
Science (New York, N.Y.)352(6291)1341-4(2016 Jun)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

CCDC151 mutations cause primary ciliary dyskinesia by disruption of the outer dynein arm docking complex formation.
Hjeij R, Onoufriadis A, Watson CM, Slagle CE, Klena NT, Dougherty GW, Kurkowiak M, Loges NT, Diggle CP, Morante NF, Gabriel GC, Lemke KL, Li Y, Pennekamp P, Menchen T, Konert F, Marthin JK, Mans DA, Letteboer SJ, Werner C, Burgoyne T, Westermann C, Rutman A, Carr IM, O'Callaghan C, Moya E, Chung EM, , Sheridan E, Nielsen KG, Roepman R, Bartscherer K, Burdine RD, Lo CW, Omran H, Mitchison HM
American journal of human genetics95(3)257-74(2014 Sep)

The coiled-coil domain containing protein CCDC151 is required for the function of IFT-dependent motile cilia in animals.
Jerber J, Baas D, Soulavie F, Chhin B, Cortier E, Vesque C, Thomas J, Durand B
Human molecular genetics23(3)563-77(2014 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ccdc151 is required for efficient cilia motility in the zebrafish.
Title: The coiled-coil domain containing protein CCDC151 is required for the function of IFT-dependent motile cilia in animals.

The following ccdc151 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ccdc151 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa00631	NM_001077369.2 Latest version!	Danio rerio coiled-coil domain containing 151 (ccdc151), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ccdc151 ( NM_001077369.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001070837.2 Danio rerio coiled-coil domain containing 151 (ccdc151), mRNA.

Price & Availability↑

CloneID	ODa00631
Clone ID Related Accession (Same CDS sequence)	NM_001077369.2
Accession Version	NM_001077369.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-07
Organism	Danio rerio(zebrafish)
Product	coiled-coil domain-containing protein 151
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR394534.6. On Aug 6, 2009 this sequence version replaced NM_001077369.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC124606.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGCCCGGCA CGTCGGTCTC TGGTGGCCTT ATGGTCCCTA TTCATGATAA AATTTCGGAG 
CTCCAAAGAA AAATCCAACT TCTTGAGGGA GACAGAAGCG CGTATTTCGA AAGCTCTCAG 
TCTGCCATTA AGAAGAACAG AGAGAGCATC CTACAGCTGA GACAAGAAAA CAAAAACCTG 
CACAAGAAAC TGGCTGAGAG CGATGAACAA GTTATCAAGG ATGTTTTTCA AGGCTATGGT 
GTGGAGAAAG CACCATTCAG GAACATGCCT GTGAAGGCAG CTCGTACAGT GCTGGAGAAG 
CAGGTGCGTG ATAAAATGAA GAAGTTGAAT GCTATGAAAC ACACCACTCA GAAACAGAGG 
CAGCGTTTAG AGGACCTGAA GCTGCAGTAC CAGAGCATGA AGCCACACAA CAAAAGCCCT 
CTGCCTGACA CCCAGAAACA GGAGGACGAG GAAAAGAAAT TGCGTATTCT TGAGAACCGT 
TTGGAGAAAA CGCAGCTGAA ATGCCATGAA GCGGAGCACA TAATGCGAGG ATACCTGAAA 
CTGAAGGAAC ATCTGCAGGA AGAGAGTCTT ACATTTCAGC CACAGCTAGA CAGGATGGAG 
ACAGAGATTC ACAGACAGAC ACAAGTGTTT AAAGACCTGC AGGTCATGAA CAGTGACGCT 
CATCTGTCTA AGGATGCTGC CAAGGCTGAG CTGCAGCTTC AGGAGGAGCA GGTGTACAGA 
GAGCGCAAAG AGAGAGAGAA AATCCTCTCC CGCTACAAAA AGCAGACGGT GGAGAGAATG 
AATCAGGCAG AGAGGATGAA GAGAAGACCT CAATGGGCCA CCATGCACCC CGATGAGCTG 
AGCAGCGAGG CCCAGCGCAG CGCCATCATA GTAGGAGAAG AAGCAGAAAC CACATCTACG 
TTTGAAGAAG CTTTCCAGCG CATCAAAGAA GCCACTGGAG TCACAGACTC ACAGGAAATA 
GTGGACAGGT TTGTCTCTCA GGGAGAAACT CATGGTCACT TGGAGAGGAT GAAAGCAGAA 
AATGAGAGAA TGCTGCAGGA ACTGAAAGAA GAGAGAAACA CACTACAGAC TCAGCTTCAG 
GATATGAAAT ACTCACGAGA GACGGAACTC TCAAGCGCGG AGCAGATGCT GCAGGAGTGT 
GAGCTTCGTC TACAGCAGGA GCAGCAGCGT CGTGATGCAG CTAAAGATCA TCTGGACAGA 
CTCACACACA TACTAAACAC TGTCAGAGCA GGAGTGCAGC AGCTCAGCGA CAAACTACAG 
CACATCCCAC CGATGAAGGG TCCGGAACCC CAGCTGTCTC CAGACTCAGA CGAGCACATA 
CTGGAGCTGA TGTCTGAGGC TGAGGAGAAA CTCATGCTGC TGAAAGAGGA ACTGCAGGGC 
AATGATCTGG CAACCATCAT GAAGGAGATG GAGGAGGAAG AGTTCCATGC CACTATAGCG 
AGAAAAATAC CCCAGTACAA CACTCGCATT CAGCTGCATG AGGCCCACAA ACAGGATCCT 
TTTGACGATG AGGAGGACAG CGGCGATGAT GAGGGCGATA TCATCACCCG ATTCAGCCTG 
AAGCATCAGT CGCAGGCAAT CATTGACGCA AATACCAAGA GGAAGACTCG CATCAAAAAG 
AGGAAGGGTA AACTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070837.2
CDS	97..1734
Translation	MPGTSVSGGLMVPIHDKISELQRKIQLLEGDRSAYFESSQSAIKKNRESILQLRQENKNLHKKLAESDEQVIKDVFQGYGVEKAPFRNMPVKAARTVLEKQVRDKMKKLNAMKHTTQKQRQRLEDLKLQYQSMKPHNKSPLPDTQKQEDEEKKLRILENRLEKTQLKCHEAEHIMRGYLKLKEHLQEESLTFQPQLDRMETEIHRQTQVFKDLQVMNSDAHLSKDAAKAELQLQEEQVYRERKEREKILSRYKKQTVERMNQAERMKRRPQWATMHPDELSSEAQRSAIIVGEEAETTSTFEEAFQRIKEATGVTDSQEIVDRFVSQGETHGHLERMKAENERMLQELKEERNTLQTQLQDMKYSRETELSSAEQMLQECELRLQQEQQRRDAAKDHLDRLTHILNTVRAGVQQLSDKLQHIPPMKGPEPQLSPDSDEHILELMSEAEEKLMLLKEELQGNDLATIMKEMEEEEFHATIARKIPQYNTRIQLHEAHKQDPFDDEEDSGDDEGDIITRFSLKHQSQAIIDANTKRKTRIKKRKGKL

Target ORF information:

RefSeq Version	NM_001077369.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio coiled-coil domain containing 151 (ccdc151), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077369.2

ORF Insert Sequence:

ATGCCCGGCA CGTCGGTCTC TGGTGGCCTT ATGGTCCCTA TTCATGATAA AATTTCGGAG 
CTCCAAAGAA AAATCCAACT TCTTGAGGGA GACAGAAGCG CGTATTTCGA AAGCTCTCAG 
TCTGCCATTA AGAAGAACAG AGAGAGCATC CTACAGCTGA GACAAGAAAA CAAAAACCTG 
CACAAGAAAC TGGCTGAGAG CGATGAACAA GTTATCAAGG ATGTTTTTCA AGGCTATGGT 
GTGGAGAAAG CACCATTCAG GAACATGCCT GTGAAGGCAG CTCGTACAGT GCTGGAGAAG 
CAGGTGCGTG ATAAAATGAA GAAGTTGAAT GCTATGAAAC ACACCACTCA GAAACAGAGG 
CAGCGTTTAG AGGACCTGAA GCTGCAGTAC CAGAGCATGA AGCCACACAA CAAAAGCCCT 
CTGCCTGACA CCCAGAAACA GGAGGACGAG GAAAAGAAAT TGCGTATTCT TGAGAACCGT 
TTGGAGAAAA CGCAGCTGAA ATGCCATGAA GCGGAGCACA TAATGCGAGG ATACCTGAAA 
CTGAAGGAAC ATCTGCAGGA AGAGAGTCTT ACATTTCAGC CACAGCTAGA CAGGATGGAG 
ACAGAGATTC ACAGACAGAC ACAAGTGTTT AAAGACCTGC AGGTCATGAA CAGTGACGCT 
CATCTGTCTA AGGATGCTGC CAAGGCTGAG CTGCAGCTTC AGGAGGAGCA GGTGTACAGA 
GAGCGCAAAG AGAGAGAGAA AATCCTCTCC CGCTACAAAA AGCAGACGGT GGAGAGAATG 
AATCAGGCAG AGAGGATGAA GAGAAGACCT CAATGGGCCA CCATGCACCC CGATGAGCTG 
AGCAGCGAGG CCCAGCGCAG CGCCATCATA GTAGGAGAAG AAGCAGAAAC CACATCTACG 
TTTGAAGAAG CTTTCCAGCG CATCAAAGAA GCCACTGGAG TCACAGACTC ACAGGAAATA 
GTGGACAGGT TTGTCTCTCA GGGAGAAACT CATGGTCACT TGGAGAGGAT GAAAGCAGAA 
AATGAGAGAA TGCTGCAGGA ACTGAAAGAA GAGAGAAACA CACTACAGAC TCAGCTTCAG 
GATATGAAAT ACTCACGAGA GACGGAACTC TCAAGCGCGG AGCAGATGCT GCAGGAGTGT 
GAGCTTCGTC TACAGCAGGA GCAGCAGCGT CGTGATGCAG CTAAAGATCA TCTGGACAGA 
CTCACACACA TACTAAACAC TGTCAGAGCA GGAGTGCAGC AGCTCAGCGA CAAACTACAG 
CACATCCCAC CGATGAAGGG TCCGGAACCC CAGCTGTCTC CAGACTCAGA CGAGCACATA 
CTGGAGCTGA TGTCTGAGGC TGAGGAGAAA CTCATGCTGC TGAAAGAGGA ACTGCAGGGC 
AATGATCTGG CAACCATCAT GAAGGAGATG GAGGAGGAAG AGTTCCATGC CACTATAGCG 
AGAAAAATAC CCCAGTACAA CACTCGCATT CAGCTGCATG AGGCCCACAA ACAGGATCCT 
TTTGACGATG AGGAGGACAG CGGCGATGAT GAGGGCGATA TCATCACCCG ATTCAGCCTG 
AAGCATCAGT CGCAGGCAAT CATTGACGCA AATACCAAGA GGAAGACTCG CATCAAAAAG 
AGGAAGGGTA AACTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature.
Science (New York, N.Y.)352(6291)1341-4(2016 Jun)
Grimes DT,Boswell CW,Morante NF,Henkelman RM,Burdine RD,Ciruna B

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

CCDC151 mutations cause primary ciliary dyskinesia by disruption of the outer dynein arm docking complex formation.
American journal of human genetics95(3)257-74(2014 Sep)
Hjeij R,Onoufriadis A,Watson CM,Slagle CE,Klena NT,Dougherty GW,Kurkowiak M,Loges NT,Diggle CP,Morante NF,Gabriel GC,Lemke KL,Li Y,Pennekamp P,Menchen T,Konert F,Marthin JK,Mans DA,Letteboer SJ,Werner C,Burgoyne T,Westermann C,Rutman A,Carr IM,O'Callaghan C,Moya E,Chung EM,,Sheridan E,Nielsen KG,Roepman R,Bartscherer K,Burdine RD,Lo CW,Omran H,Mitchison HM

The coiled-coil domain containing protein CCDC151 is required for the function of IFT-dependent motile cilia in animals.
Human molecular genetics23(3)563-77(2014 Feb)
Jerber J,Baas D,Soulavie F,Chhin B,Cortier E,Vesque C,Thomas J,Durand B