cradd cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	cradd
Entrez Gene ID	450046
Full Name	CASP2 and RIPK1 domain containing adaptor with death domain
Synonyms	zgc:101717
General protein information	Preferred Names CASP2 and RIPK1 domain containing adaptor with death domain Names death domain-containing protein CRADD
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001006066.1	NP_001006066.1	death domain-containing protein CRADD

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cradd	NP_034080.1
Xenopus tropicalis (tropical clawed frog)	cradd.1	NP_001006911.1
	CRADD	XP_001105475.1
Canis lupus familiaris (dog)	CRADD	XP_005629283.1
Xenopus tropicalis (tropical clawed frog)	LOC100489885	XP_002944186.1
Homo sapiens (human)	CRADD	NP_003796.1
Pan troglodytes (chimpanzee)	CRADD	XP_509268.2
Gallus gallus (chicken)	CRADD	NP_001025919.1
Danio rerio (zebrafish)	cradd	NP_001006066.1

Gene Ontology
Bibliography

Related articles in PubMed

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Tissue factor pathway inhibitor-2: a novel gene involved in zebrafish central nervous system development.
Zhang Y, Wang L, Zhou W, Wang H, Zhang J, Deng S, Li W, Li H, Mao Z, Ma D
Developmental biology381(1)38-49(2013 Sep)

Evolution of JAK-STAT pathway components: mechanisms and role in immune system development.
Liongue C, O'Sullivan LA, Trengove MC, Ward AC
PloS one7(3)e32777(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following cradd gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cradd cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa03902	NM_001006066.1 Latest version!	Danio rerio CASP2 and RIPK1 domain containing adaptor with death domain (cradd), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

cradd ( NM_001006066.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001006066.1 Danio rerio CASP2 and RIPK1 domain containing adaptor with death domain (cradd), mRNA.

Price & Availability↑

CloneID	ODa03902
Clone ID Related Accession (Same CDS sequence)	NM_001006066.1
Accession Version	NM_001006066.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	death domain-containing protein CRADD
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083256.1. ##Evidence-Data-START## Transcript exon combination :: BC083256.1, EH539650.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGACCCAA AGCACAAAAA ACTGCTCCGA ACACAGCGGC TTTTTCTGTC CGAGGAGCTT 
TTAGTGGACG ATTTAATCAT TCAGTATTTA TATCAAGAGG AGATACTGAC GGAGAGCCAT 
TTAGAGGAGA TTCAGTCCGA GTCGTCAAGC AGAAATAAAA CGTTAAAGCT GCTGGATATT 
TTACCGAGCC GCGGAGCGAC AGCCTTCCAT CACTTCATAA AGTCACTGGA GAAAGACTTT 
CCCTGGATCA GAGACAAACT GCTGCAACTA AACGAGGAAG AAGAGTCTCC TCCTCCGCCC 
TTCACAGTTC AGTGTGGTGT TCCTGACCAC ATCCTTCTGA CCGTACCAAC CACCCTGCAT 
CTGAATCAGC TGGCATCCCG TCTGGGCTCA GAGTGGAAGT CTGTGCTGCT GGATCTGGGC 
CTGTCCTGTG CGGATCTGTA CCGGTGCTGC TCTGACCACC CGCTTGCTGT TCAGAGTCAG 
GTGCTCGCTG GGCTGGTGAT GTGGACGCAG AGGAACGGAA GAGGGGCCAC GGTGCAGCGG 
CTGATCCAGA GCCTGCAGGC TGCAGATGTC CCGCCATCTG TGCTCCAACA GGTGTTTAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001006066.1
CDS	194..796
Translation	MDPKHKKLLRTQRLFLSEELLVDDLIIQYLYQEEILTESHLEEIQSESSSRNKTLKLLDILPSRGATAFHHFIKSLEKDFPWIRDKLLQLNEEEESPPPPFTVQCGVPDHILLTVPTTLHLNQLASRLGSEWKSVLLDLGLSCADLYRCCSDHPLAVQSQVLAGLVMWTQRNGRGATVQRLIQSLQAADVPPSVLQQVFK

Target ORF information:

RefSeq Version	NM_001006066.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio CASP2 and RIPK1 domain containing adaptor with death domain (cradd), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001006066.1

ORF Insert Sequence:

ATGGACCCAA AGCACAAAAA ACTGCTCCGA ACACAGCGGC TTTTTCTGTC CGAGGAGCTT 
TTAGTGGACG ATTTAATCAT TCAGTATTTA TATCAAGAGG AGATACTGAC GGAGAGCCAT 
TTAGAGGAGA TTCAGTCCGA GTCGTCAAGC AGAAATAAAA CGTTAAAGCT GCTGGATATT 
TTACCGAGCC GCGGAGCGAC AGCCTTCCAT CACTTCATAA AGTCACTGGA GAAAGACTTT 
CCCTGGATCA GAGACAAACT GCTGCAACTA AACGAGGAAG AAGAGTCTCC TCCTCCGCCC 
TTCACAGTTC AGTGTGGTGT TCCTGACCAC ATCCTTCTGA CCGTACCAAC CACCCTGCAT 
CTGAATCAGC TGGCATCCCG TCTGGGCTCA GAGTGGAAGT CTGTGCTGCT GGATCTGGGC 
CTGTCCTGTG CGGATCTGTA CCGGTGCTGC TCTGACCACC CGCTTGCTGT TCAGAGTCAG 
GTGCTCGCTG GGCTGGTGAT GTGGACGCAG AGGAACGGAA GAGGGGCCAC GGTGCAGCGG 
CTGATCCAGA GCCTGCAGGC TGCAGATGTC CCGCCATCTG TGCTCCAACA GGTGTTTAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Tissue factor pathway inhibitor-2: a novel gene involved in zebrafish central nervous system development.
Developmental biology381(1)38-49(2013 Sep)
Zhang Y,Wang L,Zhou W,Wang H,Zhang J,Deng S,Li W,Li H,Mao Z,Ma D

Evolution of JAK-STAT pathway components: mechanisms and role in immune system development.
PloS one7(3)e32777(2012)
Liongue C,O'Sullivan LA,Trengove MC,Ward AC