ints12 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ints12
Entrez Gene ID	415251
Full Name	integrator complex subunit 12
Synonyms	wu:fi17f05,zgc:86602
General protein information	Preferred Names integrator complex subunit 12 Names integrator complex subunit 12 int12
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001002161.3	NP_001002161.2	integrator complex subunit 12

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	INTS12	XP_005639299.1
Rattus norvegicus (Norway rat)	Ints12	NP_001007641.1
Danio rerio (zebrafish)	ints12	NP_001002161.2
Danio rerio (zebrafish)	LOC100334713	XP_005159961.1
Gallus gallus (chicken)	INTS12	XP_420500.3
Pan troglodytes (chimpanzee)	INTS12	XP_003310450.1
Bos taurus (cattle)	INTS12	NP_001069221.1
Mus musculus (house mouse)	Ints12	NP_082203.1
Homo sapiens (human)	INTS12	NP_065128.2
	INTS12	XP_001084188.1
Xenopus tropicalis (tropical clawed frog)	ints12	NP_001072325.1

Gene Ontology
Bibliography

Related articles in PubMed

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model.
Ge L, Zhang RP, Wan F, Guo DY, Wang P, Xiang LX, Shao JZ
Molecular and cellular biology34(6)989-1002(2014 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ints12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ints12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa02116	NM_001002161.3 Latest version!	Danio rerio integrator complex subunit 12 (ints12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ints12 ( NM_001002161.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001002161.2 Danio rerio integrator complex subunit 12 (ints12), mRNA.

Price & Availability↑

CloneID	ODa02116
Clone ID Related Accession (Same CDS sequence)	NM_001002161.3
Accession Version	NM_001002161.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1440bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	integrator complex subunit 12
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC096989.1. On Aug 30, 2012 this sequence version replaced NM_001002161.2. ##Evidence-Data-START## Transcript exon combination :: BC096989.1, CT700053.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGGGA CAGTAAGTCT AGAGTTAGAC CCTATCTTTC TGAAGGGACT GGGGTATCTT 
CACTCCAAGA GCAAAGACTC GGCAGAGAAA CTCAAGGCCC TGCTAGATGA GTCTTTAGCC 
AGAGGCAGTG ACTCCATCTA TAGGAATTCA ATTAAGGAAG CTGAAGTGAG CAAAGTGTCA 
TTGCCAAAAA TGACAAAACA AGACTCCAAA TCCTCCTCAA GTTCCTCAGT GTCATCATCC 
ATCACCACCA GCAACAGCAG TAAATCAAGC ATCTCAGAGA AGTCCAAGAA AGAGAGCGAG 
AAAAGAACTT TGGAAAAAAT TAGGGTTGAT CCTGGAGAAG GAGTGGAGCC GCCTAAGAAA 
CCTCGTTTAG AGAAGCAGGA CAGTCATTCC TCTCCGATTG CTTTTCAAAC CAAGGACATT 
CCCATTCCAG ATTTCACAGA TATTGATGAA ACCAACGCTG ATGACTTTGC CATGGAAATG 
GGTCTTGCTT GTGTGGTTTG TCGACAAATG ACCGTCACTT CTGGGAATCA GCTTGTGGAG 
TGTCAAGAAT GTCATAATCT TTATCATCAA GAGTGTCACA AACCTCAGGT TACTGACAAG 
GATGTGAATG ACCCGCGACT GGTGTGGTAC TGTGCTCGGT GCACCAGGCA AATGAAACGA 
ATGGCCCAAA AGACTCAGAA ACCACCACAA AAGCCAGCTC CTGCTTTGGC AACAACAGTA 
CCTTTGTTGA AAGATCCGCT AGTCAAGAAA GCTGAACTAA AGCCAAAACC TGAAACGACA 
GGTTCATTCC AGGCCTTTAA GAGAACAGAA GTAAAGGCAA CTGCAGCATC AGGAAACTCA 
TCCAGCAGCA GTAGCAGCAG CTCGTCTTTG CCTCCGGGTC TTACAGGATG GGCCGCCTTC 
ACCAAGGCAA CCTCAAATGT AGGACCTTCC AGCACCAAGT TAAGCACCAG TCAATCAGGT 
AACAGTAAAA CATCCCCAGC TGCCTCAGGC TCCAAACCTG TGGGTCTCTC TGCTCTGGCC 
AATGTTAAAC CAGCTCTGGC CACTAAACCT TCAGGGGGAA GCAGTGCCGG AAGTGGCAAT 
GGAAACAATG GCTCTGGTAC GGTACCCTTA AAAGCACCTC CTCCGCTTAC TCTAGGTAAA 
CAGGTGTTGA GCCGCTCAGC GAGTGGAGAT AGTTTGGGGA AAATGACTGT GACGGGATCA 
TTGTCACCTG GAGCTGCACC TTCTAGCAGC CTGGGTGGCA ATGGTGGGTC AGGAGGCAAT 
GGAGCGGGCA ACGGTGGCAA TAGTGCTGGG AGTAGCAGCA GCAGTGGCAA CAACAACAAC 
AATGGAGCAA AAGCCTCGGC TGATGGCAAG GCACCCACTT CCCAAGAGTC TCAGCTCAAT 
GCTATGAAAC GCCTGCAGAT GGTGAAGAAG AAAGCGGCAC AGAAAAAACT GAAGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001002161.2
CDS	295..1734
Translation	MAGTVSLELDPIFLKGLGYLHSKSKDSAEKLKALLDESLARGSDSIYRNSIKEAEVSKVSLPKMTKQDSKSSSSSSVSSSITTSNSSKSSISEKSKKESEKRTLEKIRVDPGEGVEPPKKPRLEKQDSHSSPIAFQTKDIPIPDFTDIDETNADDFAMEMGLACVVCRQMTVTSGNQLVECQECHNLYHQECHKPQVTDKDVNDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPALATTVPLLKDPLVKKAELKPKPETTGSFQAFKRTEVKATAASGNSSSSSSSSSSLPPGLTGWAAFTKATSNVGPSSTKLSTSQSGNSKTSPAASGSKPVGLSALANVKPALATKPSGGSSAGSGNGNNGSGTVPLKAPPPLTLGKQVLSRSASGDSLGKMTVTGSLSPGAAPSSSLGGNGGSGGNGAGNGGNSAGSSSSSGNNNNNGAKASADGKAPTSQESQLNAMKRLQMVKKKAAQKKLKK

Target ORF information:

RefSeq Version	NM_001002161.3
Organism	Danio rerio(zebrafish)
Definition	Danio rerio integrator complex subunit 12 (ints12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001002161.3

ORF Insert Sequence:

ATGGCTGGGA CAGTAAGTCT AGAGTTAGAC CCTATCTTTC TGAAGGGACT GGGGTATCTT 
CACTCCAAGA GCAAAGACTC GGCAGAGAAA CTCAAGGCCC TGCTAGATGA GTCTTTAGCC 
AGAGGCAGTG ACTCCATCTA TAGGAATTCA ATTAAGGAAG CTGAAGTGAG CAAAGTGTCA 
TTGCCAAAAA TGACAAAACA AGACTCCAAA TCCTCCTCAA GTTCCTCAGT GTCATCATCC 
ATCACCACCA GCAACAGCAG TAAATCAAGC ATCTCAGAGA AGTCCAAGAA AGAGAGCGAG 
AAAAGAACTT TGGAAAAAAT TAGGGTTGAT CCTGGAGAAG GAGTGGAGCC GCCTAAGAAA 
CCTCGTTTAG AGAAGCAGGA CAGTCATTCC TCTCCGATTG CTTTTCAAAC CAAGGACATT 
CCCATTCCAG ATTTCACAGA TATTGATGAA ACCAACGCTG ATGACTTTGC CATGGAAATG 
GGTCTTGCTT GTGTGGTTTG TCGACAAATG ACCGTCACTT CTGGGAATCA GCTTGTGGAG 
TGTCAAGAAT GTCATAATCT TTATCATCAA GAGTGTCACA AACCTCAGGT TACTGACAAG 
GATGTGAATG ACCCGCGACT GGTGTGGTAC TGTGCTCGGT GCACCAGGCA AATGAAACGA 
ATGGCCCAAA AGACTCAGAA ACCACCACAA AAGCCAGCTC CTGCTTTGGC AACAACAGTA 
CCTTTGTTGA AAGATCCGCT AGTCAAGAAA GCTGAACTAA AGCCAAAACC TGAAACGACA 
GGTTCATTCC AGGCCTTTAA GAGAACAGAA GTAAAGGCAA CTGCAGCATC AGGAAACTCA 
TCCAGCAGCA GTAGCAGCAG CTCGTCTTTG CCTCCGGGTC TTACAGGATG GGCCGCCTTC 
ACCAAGGCAA CCTCAAATGT AGGACCTTCC AGCACCAAGT TAAGCACCAG TCAATCAGGT 
AACAGTAAAA CATCCCCAGC TGCCTCAGGC TCCAAACCTG TGGGTCTCTC TGCTCTGGCC 
AATGTTAAAC CAGCTCTGGC CACTAAACCT TCAGGGGGAA GCAGTGCCGG AAGTGGCAAT 
GGAAACAATG GCTCTGGTAC GGTACCCTTA AAAGCACCTC CTCCGCTTAC TCTAGGTAAA 
CAGGTGTTGA GCCGCTCAGC GAGTGGAGAT AGTTTGGGGA AAATGACTGT GACGGGATCA 
TTGTCACCTG GAGCTGCACC TTCTAGCAGC CTGGGTGGCA ATGGTGGGTC AGGAGGCAAT 
GGAGCGGGCA ACGGTGGCAA TAGTGCTGGG AGTAGCAGCA GCAGTGGCAA CAACAACAAC 
AATGGAGCAA AAGCCTCGGC TGATGGCAAG GCACCCACTT CCCAAGAGTC TCAGCTCAAT 
GCTATGAAAC GCCTGCAGAT GGTGAAGAAG AAAGCGGCAC AGAAAAAACT GAAGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model.
Molecular and cellular biology34(6)989-1002(2014 Mar)
Ge L,Zhang RP,Wan F,Guo DY,Wang P,Xiang LX,Shao JZ