Hmgb1 cDNA ORF clone, Crassostrea gigas(Pacific oyster)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hmgb1
Entrez Gene ID	105348423
Full Name	high mobility group box 1
Gene Type	protein-coding
Organism	Crassostrea gigas(Pacific oyster)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001305310.1	NP_001292239.1	uncharacterized protein LOC105348423

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

High mobility group box 1 can enhance NF-?B activation and act as a pro-inflammatory molecule in the Pacific oyster, Crassostrea gigas.
Li J, Zhang Y, Xiang Z, Xiao S, Yu F, Yu Z
Fish & shellfish immunology35(1)63-70(2013 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hmgb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hmgb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCr126241	NM_001305310.1 Latest version!	Crassostrea gigas high mobility group box 1 (Hmgb1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hmgb1 ( NM_001305310.1 ) cDNA ORF clone, Crassostrea gigas(Pacific oyster) -> NP_001292239.1 Crassostrea gigas high mobility group box 1 (Hmgb1), mRNA.

Price & Availability↑

CloneID	OCr126241
Clone ID Related Accession (Same CDS sequence)	NM_001305310.1
Accession Version	NM_001305310.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 609bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-04
Organism	Crassostrea gigas(Pacific oyster)
Product	uncharacterized protein LOC105348423
Comment	Comment: PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from KC516860.1. On Mar 7, 2015 this sequence version replaced XM_011457823.1. ##Evidence-Data-START## Transcript exon combination :: KC516860.1, HS114457.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00139188, SAMN00139189 [ECO:0000350] ##Evidence-Data-END##

ATGGGTCGCC CAAAAGCAGA AGGCAGCAGG AAGAGGAAAG CTAAGGACCC TAACAGACCA 
AAGAGGGCCA CATCTGCCTA TTTCTTCTTT CTTTCTAAAA TGAGGGAGGA TTCCAAAAAA 
GCAGGAAAAC CCATCACAAA AATTGCTGAA TTTACAAAAG AATGTTCAGC AAAATGGGCC 
AAAATGAATG AGAAAGATAA GGAGCCATTC GCCAAGAAGG CCCTAACAGA CAAGAATAGG 
TACGATGCTG AAATGGCCAT CTACAAGGGA AAAGACCCCA ACGATGCTGG CAAGCCCAAG 
AGACCACAAT CTGCGTATTT CTGCTTTTTG GCCGATTTCA GGTTAAAGAT GAAAGGAAAG 
GATATTGATC ACAAAGAAAT CATCAAAATG GCTGGTGAAG CCTGGAGAAA TCTGGATGAC 
AATGAGAAAA AGCCATTTGA AAAGTTAGCC CAGAAAGAAC AAGAGAAATA TGAACAAGCT 
CTTAGTGACT GGAGAAAGGG AGGCGGTGGT GCATCCCCAT CAAAGAAACC CAAACAGGAG 
GAGAATGGCG ATGAAGATGA GGAAGATGAA GAAGAGGAGG AAGATGATGA TGATGAAGAT 
GATGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001292239.1
CDS	146..754
Translation	MGRPKAEGSRKRKAKDPNRPKRATSAYFFFLSKMREDSKKAGKPITKIAEFTKECSAKWAKMNEKDKEPFAKKALTDKNRYDAEMAIYKGKDPNDAGKPKRPQSAYFCFLADFRLKMKGKDIDHKEIIKMAGEAWRNLDDNEKKPFEKLAQKEQEKYEQALSDWRKGGGGASPSKKPKQEENGDEDEEDEEEEEDDDDEDDE

Target ORF information:

RefSeq Version	NM_001305310.1
Organism	Crassostrea gigas(Pacific oyster)
Definition	Crassostrea gigas high mobility group box 1 (Hmgb1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001305310.1

ORF Insert Sequence:

ATGGGTCGCC CAAAAGCAGA AGGCAGCAGG AAGAGGAAAG CTAAGGACCC TAACAGACCA 
AAGAGGGCCA CATCTGCCTA TTTCTTCTTT CTTTCTAAAA TGAGGGAGGA TTCCAAAAAA 
GCAGGAAAAC CCATCACAAA AATTGCTGAA TTTACAAAAG AATGTTCAGC AAAATGGGCC 
AAAATGAATG AGAAAGATAA GGAGCCATTC GCCAAGAAGG CCCTAACAGA CAAGAATAGG 
TACGATGCTG AAATGGCCAT CTACAAGGGA AAAGACCCCA ACGATGCTGG CAAGCCCAAG 
AGACCACAAT CTGCGTATTT CTGCTTTTTG GCCGATTTCA GGTTAAAGAT GAAAGGAAAG 
GATATTGATC ACAAAGAAAT CATCAAAATG GCTGGTGAAG CCTGGAGAAA TCTGGATGAC 
AATGAGAAAA AGCCATTTGA AAAGTTAGCC CAGAAAGAAC AAGAGAAATA TGAACAAGCT 
CTTAGTGACT GGAGAAAGGG AGGCGGTGGT GCATCCCCAT CAAAGAAACC CAAACAGGAG 
GAGAATGGCG ATGAAGATGA GGAAGATGAA GAAGAGGAGG AAGATGATGA TGATGAAGAT 
GATGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High mobility group box 1 can enhance NF-?B activation and act as a pro-inflammatory molecule in the Pacific oyster, Crassostrea gigas.
Fish & shellfish immunology35(1)63-70(2013 Jul)
Li J,Zhang Y,Xiang Z,Xiao S,Yu F,Yu Z