| Gene Symbol | amph-1 |
| Entrez Gene ID | 177797 |
| Full Name | AMPHiphysin homolog |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » amph-1 cDNA ORF clone
| Gene Symbol | amph-1 |
| Entrez Gene ID | 177797 |
| Full Name | AMPHiphysin homolog |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_069310.3 | NP_501711.1 | AMPHiphysin homolog |
| NM_069310.4 | NP_501711.1 | AMPHiphysin homolog |
| Pan troglodytes (chimpanzee) | AMPH | XP_003318313.1 |
| Rattus norvegicus (Norway rat) | Amph | NP_071553.1 |
| Rattus norvegicus (Norway rat) | LOC100910792 | XP_006254144.1 |
| Caenorhabditis elegans (roundworm) | amph-1 | NP_501711.1 |
| Xenopus tropicalis (tropical clawed frog) | amph | NP_001096507.1 |
| Homo sapiens (human) | AMPH | NP_001626.1 |
| Canis lupus familiaris (dog) | AMPH | XP_533085.3 |
| Mus musculus (house mouse) | Amph | NP_778172.1 |
| Danio rerio (zebrafish) | amph | NP_957125.1 |
| Gallus gallus (chicken) | AMPH | NP_001004398.1 |
| AMPH | XP_001100126.1 | |
| Bos taurus (cattle) | AMPH | NP_001091599.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
the loss of TBC-2 or AMPH-1 leads to abnormally high spatial overlap of RAB-5 and RAB-10. RAB-10 and AMPH-1 mediated down-regulation of RAB-5 is an important step in recycling, required for cargo exit from early endosomes
Title: Basolateral Endocytic Recycling Requires RAB-10 and AMPH-1 Mediated Recruitment of RAB-5 GAP TBC-2 to Endosomes.
show that endogenous C. elegans AMPH-1 colocalizes with RME-1 on recycling endosomes in vivo, that amph-1-deletion mutants are defective in recycling endosome morphology and function.
Title: AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling.
The following amph-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the amph-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa344384 | |
| Clone ID Related Accession (Same CDS sequence) | NM_069310.3 , NM_069310.4 | |
| Accession Version | NM_069310.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | AMPHiphysin homolog | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_069310.2. COMPLETENESS: incomplete on both ends. | |
1 | ATGGCTGACT TGTTCAACAA ACATCTGAAA AAAGCAACGA ATCGTACCAA GGAAAAACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_501711.1 |
| CDS | 1..1386 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_069310.3 |
1 | ATGGCTGACT TGTTCAACAA ACATCTGAAA AAAGCAACGA ATCGTACCAA GGAAAAACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa344384 | |
| Clone ID Related Accession (Same CDS sequence) | NM_069310.3 , NM_069310.4 | |
| Accession Version | NM_069310.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | AMPHiphysin homolog | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_069310.3. | |
1 | ATGGCTGACT TGTTCAACAA ACATCTGAAA AAAGCAACGA ATCGTACCAA GGAAAAACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_501711.1 |
| CDS | 195..1580 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_069310.4 |
1 | ATGGCTGACT TGTTCAACAA ACATCTGAAA AAAGCAACGA ATCGTACCAA GGAAAAACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |