| Gene Symbol | lin-45 |
| Entrez Gene ID | 177436 |
| Full Name | Raf homolog serine/threonine-protein kinase |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » lin-45 cDNA ORF clone
| Gene Symbol | lin-45 |
| Entrez Gene ID | 177436 |
| Full Name | Raf homolog serine/threonine-protein kinase |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_001306913.1 | NP_001293842.1 | Raf homolog serine/threonine-protein kinase |
| NM_171368.3 | NP_741431.2 | Raf homolog serine/threonine-protein kinase |
| NM_171367.6 | NP_741430.3 | Raf homolog serine/threonine-protein kinase |
| NM_001306913.2 | NP_001293842.1 | Raf homolog serine/threonine-protein kinase |
| NM_001372851.1 | NP_001360335.1 | Raf homolog serine/threonine-protein kinase |
| NM_171368.2 | NP_741431.2 | Raf homolog serine/threonine-protein kinase |
| NM_001306915.1 | NP_001293844.1 | Raf homolog serine/threonine-protein kinase |
| NM_171367.5 | NP_741430.3 | Raf homolog serine/threonine-protein kinase |
| NM_001306912.1 | NP_001293841.1 | Raf homolog serine/threonine-protein kinase |
| NM_001306914.1 | NP_001293843.1 | Raf homolog serine/threonine-protein kinase |
| NM_001306912.2 | NP_001293841.1 | Raf homolog serine/threonine-protein kinase |
| NM_001306914.2 | NP_001293843.1 | Raf homolog serine/threonine-protein kinase |
| Mus musculus (house mouse) | Braf | NP_647455.3 |
| Rattus norvegicus (Norway rat) | Braf | XP_006236418.1 |
| Gallus gallus (chicken) | BRAF | NP_990633.1 |
| Caenorhabditis elegans (roundworm) | lin-45 | NP_741430.3 |
| Pan troglodytes (chimpanzee) | BRAF | XP_003951208.1 |
| LOC693554 | XP_002803541.1 | |
| Bos taurus (cattle) | BRAF | XP_005205968.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP004699 | XP_318144.4 |
| Canis lupus familiaris (dog) | BRAF | XP_005629607.1 |
| Drosophila melanogaster (fruit fly) | phl | NP_525047.1 |
| Xenopus tropicalis (tropical clawed frog) | braf | XP_004912520.1 |
| Danio rerio (zebrafish) | braf | NP_991307.2 |
| Homo sapiens (human) | BRAF | NP_004324.2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Genetic analysis indicates that lin-45 and protein kinase C (PKC)-1 act together to regulate nose touch response; these results functionally link two conserved signaling pathways in adult C. elegans neurons and define distinct roles for PKC genes in vivo.
Title: PKC-1 acts with the ERK MAPK signaling pathway to regulate Caenorhabditis elegans mechanosensory response.
Connector/eNhancer of KSR promotes LIN-45 Raf activation at a step between the dephosphorylation of inhibitory sites in the regulatory domain and activating phosphorylation in the kinase domain
Title: Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling.
The following lin-45 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lin-45 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa342114 | |
| Clone ID Related Accession (Same CDS sequence) | NM_171368.3 , NM_171368.2 | |
| Accession Version | NM_171368.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2568bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_171368.2. COMPLETENESS: incomplete on the 5' end. | |
1 | ATGTCTGCAA TGGCTGTACT GTATTCAGTT TGTCACTTTC ATGGAGGCTG GAATCGTCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_741431.2 |
| CDS | 1..2568 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_171368.3 |
1 | ATGTCTGCAA TGGCTGTACT GTATTCAGTT TGTCACTTTC ATGGAGGCTG GAATCGTCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa342114 | |
| Clone ID Related Accession (Same CDS sequence) | NM_171368.3 , NM_171368.2 | |
| Accession Version | NM_171368.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2568bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Apr 20, 2015 this sequence version replaced NM_171368.1. COMPLETENESS: incomplete on both ends. | |
1 | ATGTCTGCAA TGGCTGTACT GTATTCAGTT TGTCACTTTC ATGGAGGCTG GAATCGTCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_741431.2 |
| CDS | 1..2568 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_171368.2 |
1 | ATGTCTGCAA TGGCTGTACT GTATTCAGTT TGTCACTTTC ATGGAGGCTG GAATCGTCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa343365 | |
| Clone ID Related Accession (Same CDS sequence) | NM_171367.6 , NM_171367.5 | |
| Accession Version | NM_171367.6 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2442bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_171367.5. | |
1 | ATGAGTCGGA TTAATTTCAA AAAGTCATCG GCGTCGACCA CCCCGACGAG CCCACATTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_741430.3 |
| CDS | 55..2496 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_171367.6 |
1 | ATGAGTCGGA TTAATTTCAA AAAGTCATCG GCGTCGACCA CCCCGACGAG CCCACATTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa343365 | |
| Clone ID Related Accession (Same CDS sequence) | NM_171367.6 , NM_171367.5 | |
| Accession Version | NM_171367.5 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2442bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_171367.4. COMPLETENESS: incomplete on both ends. | |
1 | ATGAGTCGGA TTAATTTCAA AAAGTCATCG GCGTCGACCA CCCCGACGAG CCCACATTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_741430.3 |
| CDS | 1..2442 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_171367.5 |
1 | ATGAGTCGGA TTAATTTCAA AAAGTCATCG GCGTCGACCA CCCCGACGAG CCCACATTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa353317 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001306912.1 , NM_001306912.2 | |
| Accession Version | NM_001306912.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2397bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. | |
1 | ATGTCTGCAA TGGCTGTACT GTATTCAGTT TGTCACTTTC ATGGAGGCTG GAATCGTCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001293841.1 |
| CDS | 1..2397 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001306912.1 |
1 | ATGTCTGCAA TGGCTGTACT GTATTCAGTT TGTCACTTTC ATGGAGGCTG GAATCGTCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa353317 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001306912.1 , NM_001306912.2 | |
| Accession Version | NM_001306912.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2397bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001306912.1. | |
1 | ATGTCTGCAA TGGCTGTACT GTATTCAGTT TGTCACTTTC ATGGAGGCTG GAATCGTCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001293841.1 |
| CDS | 149..2545 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001306912.2 |
1 | ATGTCTGCAA TGGCTGTACT GTATTCAGTT TGTCACTTTC ATGGAGGCTG GAATCGTCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa353318 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001306914.1 , NM_001306914.2 | |
| Accession Version | NM_001306914.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2346bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. | |
1 | ATGGAATGCT CTCGCGAAAC GGATCAAGCT TCGCCGATGG CAAGTCCTTC AACTCCTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001293843.1 |
| CDS | 1..2346 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001306914.1 |
1 | ATGGAATGCT CTCGCGAAAC GGATCAAGCT TCGCCGATGG CAAGTCCTTC AACTCCTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa353318 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001306914.1 , NM_001306914.2 | |
| Accession Version | NM_001306914.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2346bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001306914.1. | |
1 | ATGGAATGCT CTCGCGAAAC GGATCAAGCT TCGCCGATGG CAAGTCCTTC AACTCCTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001293843.1 |
| CDS | 164..2509 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001306914.2 |
1 | ATGGAATGCT CTCGCGAAAC GGATCAAGCT TCGCCGATGG CAAGTCCTTC AACTCCTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa353319 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001306913.1 , NM_001306913.2 | |
| Accession Version | NM_001306913.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2517bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. | |
1 | ATGGAATGCT CTCGCGAAAC GAAGTCACCT GTCACATCAT CTCAAACGCC ATCATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001293842.1 |
| CDS | 1..2517 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001306913.1 |
1 | ATGGAATGCT CTCGCGAAAC GAAGTCACCT GTCACATCAT CTCAAACGCC ATCATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa353319 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001306913.1 , NM_001306913.2 | |
| Accession Version | NM_001306913.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2517bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001306913.1. | |
1 | ATGGAATGCT CTCGCGAAAC GAAGTCACCT GTCACATCAT CTCAAACGCC ATCATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001293842.1 |
| CDS | 164..2680 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001306913.2 |
1 | ATGGAATGCT CTCGCGAAAC GAAGTCACCT GTCACATCAT CTCAAACGCC ATCATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa353320 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001372851.1 , NM_001306915.1 | |
| Accession Version | NM_001372851.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2310bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). | |
1 | ATGGCAAGTC CTTCAACTCC TCTTTATCCA AAGCACAGTG ATAGTCTTCA TTCGTTATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001360335.1 |
| CDS | 104..2413 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001372851.1 |
1 | ATGGCAAGTC CTTCAACTCC TCTTTATCCA AAGCACAGTG ATAGTCTTCA TTCGTTATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa353320 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001372851.1 , NM_001306915.1 | |
| Accession Version | NM_001306915.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2310bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Raf homolog serine/threonine-protein kinase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. | |
1 | ATGGCAAGTC CTTCAACTCC TCTTTATCCA AAGCACAGTG ATAGTCTTCA TTCGTTATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001293844.1 |
| CDS | 1..2310 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001306915.1 |
1 | ATGGCAAGTC CTTCAACTCC TCTTTATCCA AAGCACAGTG ATAGTCTTCA TTCGTTATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |