CD40 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	CD40
Entrez Gene ID	286849
Full Name	CD40 molecule
Synonyms	TNFRSF5
General protein information	Preferred Names CD40 molecule Names tumor necrosis factor receptor superfamily member 5 B-cell surface antigen CD40 CD40 molecule, TNF receptor superfamily member 5 CD40L receptor tumor necrosis factor receptor superfamily, member 5
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
XM_015474118.1	XP_015329604.1	tumor necrosis factor receptor superfamily member 5 isoform X2
XM_010811368.2	XP_010809670.1	tumor necrosis factor receptor superfamily member 5 isoform X3
NM_001105611.2	NP_001099081.1	tumor necrosis factor receptor superfamily member 5 precursor
XM_015474118.2	XP_015329604.2	tumor necrosis factor receptor superfamily member 5 isoform X2
XM_005214504.3	XP_005214561.1	tumor necrosis factor receptor superfamily member 5 isoform X1
XM_005214504.4	XP_005214561.2	tumor necrosis factor receptor superfamily member 5 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CD40	XP_003317038.2
Canis lupus familiaris (dog)	CD40	NP_001002982.1
Bos taurus (cattle)	CD40	NP_001099081.1
Gallus gallus (chicken)	CD40	NP_989996.1
Homo sapiens (human)	CD40	NP_001241.1
	CD40	XP_001104333.1
Mus musculus (house mouse)	Cd40	NP_035741.2
Rattus norvegicus (Norway rat)	Cd40	NP_599187.1
Xenopus tropicalis (tropical clawed frog)	cd40	NP_001138688.1

Gene Ontology
Bibliography

Related articles in PubMed

Clinical disease upregulates expression of CD40 and CD40 ligand on peripheral blood mononuclear cells from cattle naturally infected with Mycobacterium avium subsp. paratuberculosis.
Khalifeh MS, Stabel JR
Clinical and vaccine immunology : CVI20(8)1274-82(2013 Aug)

Mycobacterium avium subspecies paratuberculosis suppresses expression of IL-12p40 and iNOS genes induced by signalling through CD40 in bovine monocyte-derived macrophages.
Sommer S, Pudrith CB, Colvin CJ, Coussens PM
Veterinary immunology and immunopathology128(1-3)44-52(2009 Mar)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Cloning, expression and biological function of the bovine CD40 homologue: role in B-lymphocyte growth and differentiation in cattle.
Hirano A, Brown WC, Estes DM
Immunology90(2)294-300(1997 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results demonstrated greater CD40 and CD40L expression on fresh mononuclear leukocytes obtained from animals in the clinical stage of Johne's Disease.
Title: Clinical disease upregulates expression of CD40 and CD40 ligand on peripheral blood mononuclear cells from cattle naturally infected with Mycobacterium avium subsp. paratuberculosis.

study investigated the hypothesis that CD40 signalling is impaired in Mycobacterium avium subspecies paratuberculosis-infected macrophages
Title: Mycobacterium avium subspecies paratuberculosis suppresses expression of IL-12p40 and iNOS genes induced by signalling through CD40 in bovine monocyte-derived macrophages.

The following CD40 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CD40 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa01212	NM_001105611.2 Latest version!	Bos taurus CD40 molecule (CD40), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OBa25292	XM_005214504.3 Latest version!	Bos taurus CD40 molecule (CD40), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OBa25293	XM_015474118.1 Latest version!	Bos taurus CD40 molecule (CD40), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OBa45522	XM_010811368.2 Latest version!	Bos taurus CD40 molecule (CD40), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa221453	XM_005214504.4 Latest version!	Bos taurus CD40 molecule (CD40), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OBa221454	XM_015474118.2 Latest version!	Bos taurus CD40 molecule (CD40), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CD40 ( NM_001105611.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001099081.1 Bos taurus CD40 molecule (CD40), mRNA.

Price & Availability↑

CloneID	OBa01212
Clone ID Related Accession (Same CDS sequence)	NM_001105611.2
Accession Version	NM_001105611.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Bos taurus(cattle)
Product	tumor necrosis factor receptor superfamily member 5 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC134765.1. On Aug 30, 2012 this sequence version replaced NM_001105611.1. ##Evidence-Data-START## Transcript exon combination :: BC134765.1, EV649311.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145415 [ECO:0000348] ##Evidence-Data-END##

ATGGTTCGTT TGCCACTGCA GTGTCTCTTC TGGGGCTTCT TTCTGACCGC CGTCCACTCA 
GAACCAGCCA CTGCTTGTGG AGAGAAGCAA TACCCAGTGA ACAGTCTTTG CTGTGATTTG 
TGCCCGCCGG GACAGAAACT GGTGAACGAC TGCACAGAGG TCAGCAAAAC AGAATGCCAG 
TCCTGCGGTA AAGGCGAATT CTTGTCCACC TGGAACAGAG AGAAATACTG TCACGAGCAC 
AGATACTGCA ACCCCAACCT AGGGCTCCGG ATCCAGAGCG AGGGCACCTT GAATACAGAC 
ACCACTTGTG TATGTGTCGA AGGCCAACAC TGTACCAGTC ACACCTGCGA AAGTTGCACG 
CCCCACAGCT TGTGTCTCCC TGGCTTCGGG GTCAAGCAGA TCGCTACAGG GCTTTTGGAT 
ACCGTCTGTG AACCCTGCCC GCTCGGCTTC TTCTCCAACG TGTCATCTGC TTTTGAAAAG 
TGTCACCGTT GGACAAGCTG CGAGAGAAAA GGCCTGGTGG AACAACACGT GGGGACGAAC 
AAGACAGATG TTGTCTGCGG TTTCCAGAGT CGGATGAGGA CCCTGGTGGT GATCCCCGTC 
ACGATGGGAG TCCTGTTTGC TGTCCTGTTG GTATCTGCCT GTATCAGGAA CATAACCAAG 
AAGCGGCAGG CTAAGGCCCT GCACCCTACG GCTGAAAGGC AGGATCCCGT GGAGACGATT 
GATCCGGAGG ATTTTCCCGG CCCCCACCCG CCTCCTCCGG TGCAAGAGAC CTTATGCTGG 
TGTCAGCCGG TCGCCCAGGA GGACGGCAAA GAGAGCCGCA TCTCCGTGCA GGAGCGAGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099081.1
CDS	47..889
Translation	MVRLPLQCLFWGFFLTAVHSEPATACGEKQYPVNSLCCDLCPPGQKLVNDCTEVSKTECQSCGKGEFLSTWNREKYCHEHRYCNPNLGLRIQSEGTLNTDTTCVCVEGQHCTSHTCESCTPHSLCLPGFGVKQIATGLLDTVCEPCPLGFFSNVSSAFEKCHRWTSCERKGLVEQHVGTNKTDVVCGFQSRMRTLVVIPVTMGVLFAVLLVSACIRNITKKRQAKALHPTAERQDPVETIDPEDFPGPHPPPPVQETLCWCQPVAQEDGKESRISVQERE

Target ORF information:

RefSeq Version	NM_001105611.2
Organism	Bos taurus(cattle)
Definition	Bos taurus CD40 molecule (CD40), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105611.2

ORF Insert Sequence:

ATGGTTCGTT TGCCACTGCA GTGTCTCTTC TGGGGCTTCT TTCTGACCGC CGTCCACTCA 
GAACCAGCCA CTGCTTGTGG AGAGAAGCAA TACCCAGTGA ACAGTCTTTG CTGTGATTTG 
TGCCCGCCGG GACAGAAACT GGTGAACGAC TGCACAGAGG TCAGCAAAAC AGAATGCCAG 
TCCTGCGGTA AAGGCGAATT CTTGTCCACC TGGAACAGAG AGAAATACTG TCACGAGCAC 
AGATACTGCA ACCCCAACCT AGGGCTCCGG ATCCAGAGCG AGGGCACCTT GAATACAGAC 
ACCACTTGTG TATGTGTCGA AGGCCAACAC TGTACCAGTC ACACCTGCGA AAGTTGCACG 
CCCCACAGCT TGTGTCTCCC TGGCTTCGGG GTCAAGCAGA TCGCTACAGG GCTTTTGGAT 
ACCGTCTGTG AACCCTGCCC GCTCGGCTTC TTCTCCAACG TGTCATCTGC TTTTGAAAAG 
TGTCACCGTT GGACAAGCTG CGAGAGAAAA GGCCTGGTGG AACAACACGT GGGGACGAAC 
AAGACAGATG TTGTCTGCGG TTTCCAGAGT CGGATGAGGA CCCTGGTGGT GATCCCCGTC 
ACGATGGGAG TCCTGTTTGC TGTCCTGTTG GTATCTGCCT GTATCAGGAA CATAACCAAG 
AAGCGGCAGG CTAAGGCCCT GCACCCTACG GCTGAAAGGC AGGATCCCGT GGAGACGATT 
GATCCGGAGG ATTTTCCCGG CCCCCACCCG CCTCCTCCGG TGCAAGAGAC CTTATGCTGG 
TGTCAGCCGG TCGCCCAGGA GGACGGCAAA GAGAGCCGCA TCTCCGTGCA GGAGCGAGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD40 ( XM_005214504.3 ) cDNA ORF clone, Bos taurus(cattle) -> XP_005214561.1 Bos taurus CD40 molecule (CD40), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa25292
Clone ID Related Accession (Same CDS sequence)	XM_005214504.3
Accession Version	XM_005214504.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	tumor necrosis factor receptor superfamily member 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104370.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005214504.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTCGTT TGCCACTGCA GTGTCTCTTC TGGGGCTTCT TTCTGACCGC CGTCCACTCA 
GAACCAGCCA CTGCTTGTGG AGAGAAGCAA TACCCAGTGA ACAGTCTTTG CTGTGATTTG 
TGCCCGCCGG GACAGAAACT GGTGAACGAC TGCACAGAGG TCAGCAAAAC AGAATGCCAG 
TCCTGCGGTA AAGGCGAATT CTTGTCCACC TGGAACAGAG AGAAATACTG TCACGAGCAC 
AGATACTGCA ACCCCAACCT AGGGCTCCGG ATCCAGAGCG AGGGCACCTT GAATACAGAC 
ACCACTTGTG TATGTGTCGA AGGCCAACAC TGTACCAGTC ACACCTGCGA AAGTTGCACG 
CCCCACAGCT TGTGTCTCCC TGGCTTCGGG GTCAAGCAGA TCGCTACAGG GCTTTTGGAT 
ACCGTCTGTG AACCCTGCCC GCTCGGCTTC TTCTCCAACG TGTCATCTGC TTTTGAAAAG 
TGTCACCGTT GGACAAGCTG CGAGAGAAAA GGCCTGGTGG AACAACACGT GGGGACGAAC 
AAGACAGATG TTGTCTGCGG TTTCCAGAGT CGGATGAGGA CCCTGGTGGT GATCCCCGTC 
ACGATGGGAG TCCTGTTTGC TGTCCTGTTG GTATCTGCCT GTATCAGTGA GTCCCCAGGG 
AACATAACCA AGAAGCGGCA GGCTAAGGCC CTGCACCCTA TGGCTGAAAG GCAGGATCCC 
GTGGAGACGA TTGATCCGGA GGATTTTCCC GGCCCCCACC CGCCTCCTCC GGTGCAAGAG 
ACCTTATGCT GGTGTCAGCC GGTCGCCCAG GAGGACGGCA AAGAGAGCCG CATCTCCGTG 
CAGGAGCGAG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005214561.1
CDS	94..948
Translation	MVRLPLQCLFWGFFLTAVHSEPATACGEKQYPVNSLCCDLCPPGQKLVNDCTEVSKTECQSCGKGEFLSTWNREKYCHEHRYCNPNLGLRIQSEGTLNTDTTCVCVEGQHCTSHTCESCTPHSLCLPGFGVKQIATGLLDTVCEPCPLGFFSNVSSAFEKCHRWTSCERKGLVEQHVGTNKTDVVCGFQSRMRTLVVIPVTMGVLFAVLLVSACISESPGNITKKRQAKALHPMAERQDPVETIDPEDFPGPHPPPPVQETLCWCQPVAQEDGKESRISVQERE

Target ORF information:

RefSeq Version	XM_005214504.3
Organism	Bos taurus(cattle)
Definition	Bos taurus CD40 molecule (CD40), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005214504.3

ORF Insert Sequence:

ATGGTTCGTT TGCCACTGCA GTGTCTCTTC TGGGGCTTCT TTCTGACCGC CGTCCACTCA 
GAACCAGCCA CTGCTTGTGG AGAGAAGCAA TACCCAGTGA ACAGTCTTTG CTGTGATTTG 
TGCCCGCCGG GACAGAAACT GGTGAACGAC TGCACAGAGG TCAGCAAAAC AGAATGCCAG 
TCCTGCGGTA AAGGCGAATT CTTGTCCACC TGGAACAGAG AGAAATACTG TCACGAGCAC 
AGATACTGCA ACCCCAACCT AGGGCTCCGG ATCCAGAGCG AGGGCACCTT GAATACAGAC 
ACCACTTGTG TATGTGTCGA AGGCCAACAC TGTACCAGTC ACACCTGCGA AAGTTGCACG 
CCCCACAGCT TGTGTCTCCC TGGCTTCGGG GTCAAGCAGA TCGCTACAGG GCTTTTGGAT 
ACCGTCTGTG AACCCTGCCC GCTCGGCTTC TTCTCCAACG TGTCATCTGC TTTTGAAAAG 
TGTCACCGTT GGACAAGCTG CGAGAGAAAA GGCCTGGTGG AACAACACGT GGGGACGAAC 
AAGACAGATG TTGTCTGCGG TTTCCAGAGT CGGATGAGGA CCCTGGTGGT GATCCCCGTC 
ACGATGGGAG TCCTGTTTGC TGTCCTGTTG GTATCTGCCT GTATCAGTGA GTCCCCAGGG 
AACATAACCA AGAAGCGGCA GGCTAAGGCC CTGCACCCTA TGGCTGAAAG GCAGGATCCC 
GTGGAGACGA TTGATCCGGA GGATTTTCCC GGCCCCCACC CGCCTCCTCC GGTGCAAGAG 
ACCTTATGCT GGTGTCAGCC GGTCGCCCAG GAGGACGGCA AAGAGAGCCG CATCTCCGTG 
CAGGAGCGAG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD40 ( XM_015474118.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_015329604.1 Bos taurus CD40 molecule (CD40), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OBa25293
Clone ID Related Accession (Same CDS sequence)	XM_015474118.1
Accession Version	XM_015474118.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	tumor necrosis factor receptor superfamily member 5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104370.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACATCT GCCTGATTTC TGAGCCAGCC TCTCAGATGG TCCACTCAGA ACCAGCCACT 
GCTTGTGGAG AGAAGCAATA CCCAGTGAAC AGTCTTTGCT GTGATTTGTG CCCGCCGGGA 
CAGAAACTGG TGAACGACTG CACAGAGGTC AGCAAAACAG AATGCCAGTC CTGCGGTAAA 
GGCGAATTCT TGTCCACCTG GAACAGAGAG AAATACTGTC ACGAGCACAG ATACTGCAAC 
CCCAACCTAG GGCTCCGGAT CCAGAGCGAG GGCACCTTGA ATACAGACAC CACTTGTGTA 
TGTGTCGAAG GCCAACACTG TACCAGTCAC ACCTGCGAAA GTTGCACGCC CCACAGCTTG 
TGTCTCCCTG GCTTCGGGGT CAAGCAGATC GCTACAGGGC TTTTGGATAC CGTCTGTGAA 
CCCTGCCCGC TCGGCTTCTT CTCCAACGTG TCATCTGCTT TTGAAAAGTG TCACCGTTGG 
ACAAGCTGCG AGAGAAAAGG CCTGGTGGAA CAACACGTGG GGACGAACAA GACAGATGTT 
GTCTGCGGTT TCCAGAGTCG GATGAGGACC CTGGTGGTGA TCCCCGTCAC GATGGGAGTC 
CTGTTTGCTG TCCTGTTGGT ATCTGCCTGT ATCAGTGAGT CCCCAGGGAA CATAACCAAG 
AAGCGGCAGG CTAAGGCCCT GCACCCTATG GCTGAAAGGC AGGATCCCGT GGAGACGATT 
GATCCGGAGG ATTTTCCCGG CCCCCACCCG CCTCCTCCGG TGCAAGAGAC CTTATGCTGG 
TGTCAGCCGG TCGCCCAGGA GGACGGCAAA GAGAGCCGCA TCTCCGTGCA GGAGCGAGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015329604.1
CDS	159..1001
Translation	MYICLISEPASQMVHSEPATACGEKQYPVNSLCCDLCPPGQKLVNDCTEVSKTECQSCGKGEFLSTWNREKYCHEHRYCNPNLGLRIQSEGTLNTDTTCVCVEGQHCTSHTCESCTPHSLCLPGFGVKQIATGLLDTVCEPCPLGFFSNVSSAFEKCHRWTSCERKGLVEQHVGTNKTDVVCGFQSRMRTLVVIPVTMGVLFAVLLVSACISESPGNITKKRQAKALHPMAERQDPVETIDPEDFPGPHPPPPVQETLCWCQPVAQEDGKESRISVQERE

Target ORF information:

RefSeq Version	XM_015474118.1
Organism	Bos taurus(cattle)
Definition	Bos taurus CD40 molecule (CD40), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015474118.1

ORF Insert Sequence:

ATGTACATCT GCCTGATTTC TGAGCCAGCC TCTCAGATGG TCCACTCAGA ACCAGCCACT 
GCTTGTGGAG AGAAGCAATA CCCAGTGAAC AGTCTTTGCT GTGATTTGTG CCCGCCGGGA 
CAGAAACTGG TGAACGACTG CACAGAGGTC AGCAAAACAG AATGCCAGTC CTGCGGTAAA 
GGCGAATTCT TGTCCACCTG GAACAGAGAG AAATACTGTC ACGAGCACAG ATACTGCAAC 
CCCAACCTAG GGCTCCGGAT CCAGAGCGAG GGCACCTTGA ATACAGACAC CACTTGTGTA 
TGTGTCGAAG GCCAACACTG TACCAGTCAC ACCTGCGAAA GTTGCACGCC CCACAGCTTG 
TGTCTCCCTG GCTTCGGGGT CAAGCAGATC GCTACAGGGC TTTTGGATAC CGTCTGTGAA 
CCCTGCCCGC TCGGCTTCTT CTCCAACGTG TCATCTGCTT TTGAAAAGTG TCACCGTTGG 
ACAAGCTGCG AGAGAAAAGG CCTGGTGGAA CAACACGTGG GGACGAACAA GACAGATGTT 
GTCTGCGGTT TCCAGAGTCG GATGAGGACC CTGGTGGTGA TCCCCGTCAC GATGGGAGTC 
CTGTTTGCTG TCCTGTTGGT ATCTGCCTGT ATCAGTGAGT CCCCAGGGAA CATAACCAAG 
AAGCGGCAGG CTAAGGCCCT GCACCCTATG GCTGAAAGGC AGGATCCCGT GGAGACGATT 
GATCCGGAGG ATTTTCCCGG CCCCCACCCG CCTCCTCCGG TGCAAGAGAC CTTATGCTGG 
TGTCAGCCGG TCGCCCAGGA GGACGGCAAA GAGAGCCGCA TCTCCGTGCA GGAGCGAGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD40 ( XM_010811368.2 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010809670.1 Bos taurus CD40 molecule (CD40), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OBa45522
Clone ID Related Accession (Same CDS sequence)	XM_010811368.2
Accession Version	XM_010811368.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	tumor necrosis factor receptor superfamily member 5 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104370.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_010811368.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTCGTT TGCCACTGCA GTGTCTCTTC TGGGGCTTCT TTCTGACCGC CGTCCACTCA 
GAACCAGCCA CTGCTTGTGG AGAGAAGCAA TACCCAGTGA ACAGTCTTTG CTGTGATTTG 
TGCCCGCCGG GACAGAAACT GGTGAACGAC TGCACAGAGG TCAGCAAAAC AGAATGCCAG 
TCCTGCGGTA AAGGCGAATT CTTGTCCACC TGGAACAGAG AGAAATACTG TCACGAGCAC 
AGATACTGCA ACCCCAACCT AGGGCTCCGG ATCCAGAGCG AGGGCACCTT GAATACAGAC 
ACCACTTGTG TATGTGTCGA AGGCCAACAC TGTACCAGTC ACACCTGCGA AAGTTGCACG 
CCCCACAGCT TGTGTCTCCC TGGCTTCGGG GTCAAGCAGA TCGCTACAGG GCTTTTGGAT 
ACCGTCTGTG AACCCTGCCC GCTCGGCTTC TTCTCCAACG TGTCATCTGC TTTTGAAAAG 
TGTCACCGTT GGACAAGGTT TCCAGAGTCG GATGAGGACC CTGGTGGTGA TCCCCGTCAC 
GATGGGAGTC CTGTTTGCTG TCCTGTTGGT ATCTGCCTGT ATCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010809670.1
CDS	93..680
Translation	MVRLPLQCLFWGFFLTAVHSEPATACGEKQYPVNSLCCDLCPPGQKLVNDCTEVSKTECQSCGKGEFLSTWNREKYCHEHRYCNPNLGLRIQSEGTLNTDTTCVCVEGQHCTSHTCESCTPHSLCLPGFGVKQIATGLLDTVCEPCPLGFFSNVSSAFEKCHRWTRFPESDEDPGGDPRHDGSPVCCPVGICLYQ

Target ORF information:

RefSeq Version	XM_010811368.2
Organism	Bos taurus(cattle)
Definition	Bos taurus CD40 molecule (CD40), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010811368.2

ORF Insert Sequence:

ATGGTTCGTT TGCCACTGCA GTGTCTCTTC TGGGGCTTCT TTCTGACCGC CGTCCACTCA 
GAACCAGCCA CTGCTTGTGG AGAGAAGCAA TACCCAGTGA ACAGTCTTTG CTGTGATTTG 
TGCCCGCCGG GACAGAAACT GGTGAACGAC TGCACAGAGG TCAGCAAAAC AGAATGCCAG 
TCCTGCGGTA AAGGCGAATT CTTGTCCACC TGGAACAGAG AGAAATACTG TCACGAGCAC 
AGATACTGCA ACCCCAACCT AGGGCTCCGG ATCCAGAGCG AGGGCACCTT GAATACAGAC 
ACCACTTGTG TATGTGTCGA AGGCCAACAC TGTACCAGTC ACACCTGCGA AAGTTGCACG 
CCCCACAGCT TGTGTCTCCC TGGCTTCGGG GTCAAGCAGA TCGCTACAGG GCTTTTGGAT 
ACCGTCTGTG AACCCTGCCC GCTCGGCTTC TTCTCCAACG TGTCATCTGC TTTTGAAAAG 
TGTCACCGTT GGACAAGGTT TCCAGAGTCG GATGAGGACC CTGGTGGTGA TCCCCGTCAC 
GATGGGAGTC CTGTTTGCTG TCCTGTTGGT ATCTGCCTGT ATCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD40 ( XM_005214504.4 ) cDNA ORF clone, Bos taurus(cattle) -> XP_005214561.2 Bos taurus CD40 molecule (CD40), transcript variant X1, mRNA.

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CloneID	OBa221453
Clone ID Related Accession (Same CDS sequence)	XM_005214504.4
Accession Version	XM_005214504.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	tumor necrosis factor receptor superfamily member 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037340.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005214504.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTCGTT TGCCACTGCA GTGTCTCTTC TGGGGCTTCT TTCTGACCGC CGTCCACTCA 
GAACCAGCCA CTGCTTGTGG AGAGAAGCAA TACCCAGTGA ACAGTCTTTG CTGTGATTTG 
TGCCCGCCGG GACAGAAACT GGTGAACGAC TGCACAGAGG TCAGCAAAAC AGAATGCCAG 
TCCTGCGGTA AAGGCGAATT CTTGTCCACC TGGAACAGAG AGAAATACTG TCACGAGCAC 
AGATACTGCA ACCCCAACCT AGGGCTCCGG ATCCAGAGCG AGGGCACCTT GAATACAGAC 
ACCACTTGTG TATGTGTCGA AGGCCAACAC TGTACCAGTC ACACCTGCGA AAGTTGCACG 
CCCCACAGCT TGTGTCTCCC TGGCTTCGGG GTCAAGCAGA TCGCTACAGG GCTTTTGGAT 
ACCGTCTGTG AACCCTGCCC GCTCGGCTTC TTCTCCAACG TGTCATCTGC TTTTGAAAAG 
TGTCACCGTT GGACAAGCTG CGAGAGAAAA GGCCTGGTGG AACAACACGT GGGGACGAAC 
AAGACAGATG TTGTCTGCGG TTTCCAGAGT CGGATGAGGA CCCTGGTGGT GATCCCCGTC 
ACGATGGGAG TCCTGTTTGC TGTCCTGTTG GTATCTGCCT GTATCAGTGA GTCCCCAGGG 
AACATAACCA AGAAGCGGCA GGCTAAGGCC CTGCACCCTA CGGCTGAAAG GCAGGATCCC 
GTGGAGACGA TTGATCCGGA GGATTTTCCC GGCCCCCACC CGCCTCCTCC GGTGCAAGAG 
ACCTTATGCT GGTGTCAGCC GGTCGCCCAG GAGGACGGCA AAGAGAGCCG CATCTCCGTG 
CAGGAGCGAG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005214561.2
CDS	105..959
Translation	MVRLPLQCLFWGFFLTAVHSEPATACGEKQYPVNSLCCDLCPPGQKLVNDCTEVSKTECQSCGKGEFLSTWNREKYCHEHRYCNPNLGLRIQSEGTLNTDTTCVCVEGQHCTSHTCESCTPHSLCLPGFGVKQIATGLLDTVCEPCPLGFFSNVSSAFEKCHRWTSCERKGLVEQHVGTNKTDVVCGFQSRMRTLVVIPVTMGVLFAVLLVSACISESPGNITKKRQAKALHPTAERQDPVETIDPEDFPGPHPPPPVQETLCWCQPVAQEDGKESRISVQERE

Target ORF information:

RefSeq Version	XM_005214504.4
Organism	Bos taurus(cattle)
Definition	Bos taurus CD40 molecule (CD40), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005214504.4

ORF Insert Sequence:

ATGGTTCGTT TGCCACTGCA GTGTCTCTTC TGGGGCTTCT TTCTGACCGC CGTCCACTCA 
GAACCAGCCA CTGCTTGTGG AGAGAAGCAA TACCCAGTGA ACAGTCTTTG CTGTGATTTG 
TGCCCGCCGG GACAGAAACT GGTGAACGAC TGCACAGAGG TCAGCAAAAC AGAATGCCAG 
TCCTGCGGTA AAGGCGAATT CTTGTCCACC TGGAACAGAG AGAAATACTG TCACGAGCAC 
AGATACTGCA ACCCCAACCT AGGGCTCCGG ATCCAGAGCG AGGGCACCTT GAATACAGAC 
ACCACTTGTG TATGTGTCGA AGGCCAACAC TGTACCAGTC ACACCTGCGA AAGTTGCACG 
CCCCACAGCT TGTGTCTCCC TGGCTTCGGG GTCAAGCAGA TCGCTACAGG GCTTTTGGAT 
ACCGTCTGTG AACCCTGCCC GCTCGGCTTC TTCTCCAACG TGTCATCTGC TTTTGAAAAG 
TGTCACCGTT GGACAAGCTG CGAGAGAAAA GGCCTGGTGG AACAACACGT GGGGACGAAC 
AAGACAGATG TTGTCTGCGG TTTCCAGAGT CGGATGAGGA CCCTGGTGGT GATCCCCGTC 
ACGATGGGAG TCCTGTTTGC TGTCCTGTTG GTATCTGCCT GTATCAGTGA GTCCCCAGGG 
AACATAACCA AGAAGCGGCA GGCTAAGGCC CTGCACCCTA CGGCTGAAAG GCAGGATCCC 
GTGGAGACGA TTGATCCGGA GGATTTTCCC GGCCCCCACC CGCCTCCTCC GGTGCAAGAG 
ACCTTATGCT GGTGTCAGCC GGTCGCCCAG GAGGACGGCA AAGAGAGCCG CATCTCCGTG 
CAGGAGCGAG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD40 ( XM_015474118.2 ) cDNA ORF clone, Bos taurus(cattle) -> XP_015329604.2 Bos taurus CD40 molecule (CD40), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OBa221454
Clone ID Related Accession (Same CDS sequence)	XM_015474118.2
Accession Version	XM_015474118.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	tumor necrosis factor receptor superfamily member 5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037340.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_015474118.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACATCT GCCTGATTTC TGAGCCAGCC TCTCAGATGG TCCACTCAGA ACCAGCCACT 
GCTTGTGGAG AGAAGCAATA CCCAGTGAAC AGTCTTTGCT GTGATTTGTG CCCGCCGGGA 
CAGAAACTGG TGAACGACTG CACAGAGGTC AGCAAAACAG AATGCCAGTC CTGCGGTAAA 
GGCGAATTCT TGTCCACCTG GAACAGAGAG AAATACTGTC ACGAGCACAG ATACTGCAAC 
CCCAACCTAG GGCTCCGGAT CCAGAGCGAG GGCACCTTGA ATACAGACAC CACTTGTGTA 
TGTGTCGAAG GCCAACACTG TACCAGTCAC ACCTGCGAAA GTTGCACGCC CCACAGCTTG 
TGTCTCCCTG GCTTCGGGGT CAAGCAGATC GCTACAGGGC TTTTGGATAC CGTCTGTGAA 
CCCTGCCCGC TCGGCTTCTT CTCCAACGTG TCATCTGCTT TTGAAAAGTG TCACCGTTGG 
ACAAGCTGCG AGAGAAAAGG CCTGGTGGAA CAACACGTGG GGACGAACAA GACAGATGTT 
GTCTGCGGTT TCCAGAGTCG GATGAGGACC CTGGTGGTGA TCCCCGTCAC GATGGGAGTC 
CTGTTTGCTG TCCTGTTGGT ATCTGCCTGT ATCAGTGAGT CCCCAGGGAA CATAACCAAG 
AAGCGGCAGG CTAAGGCCCT GCACCCTACG GCTGAAAGGC AGGATCCCGT GGAGACGATT 
GATCCGGAGG ATTTTCCCGG CCCCCACCCG CCTCCTCCGG TGCAAGAGAC CTTATGCTGG 
TGTCAGCCGG TCGCCCAGGA GGACGGCAAA GAGAGCCGCA TCTCCGTGCA GGAGCGAGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015329604.2
CDS	202..1044
Translation	MYICLISEPASQMVHSEPATACGEKQYPVNSLCCDLCPPGQKLVNDCTEVSKTECQSCGKGEFLSTWNREKYCHEHRYCNPNLGLRIQSEGTLNTDTTCVCVEGQHCTSHTCESCTPHSLCLPGFGVKQIATGLLDTVCEPCPLGFFSNVSSAFEKCHRWTSCERKGLVEQHVGTNKTDVVCGFQSRMRTLVVIPVTMGVLFAVLLVSACISESPGNITKKRQAKALHPTAERQDPVETIDPEDFPGPHPPPPVQETLCWCQPVAQEDGKESRISVQERE

Target ORF information:

RefSeq Version	XM_015474118.2
Organism	Bos taurus(cattle)
Definition	Bos taurus CD40 molecule (CD40), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015474118.2

ORF Insert Sequence:

ATGTACATCT GCCTGATTTC TGAGCCAGCC TCTCAGATGG TCCACTCAGA ACCAGCCACT 
GCTTGTGGAG AGAAGCAATA CCCAGTGAAC AGTCTTTGCT GTGATTTGTG CCCGCCGGGA 
CAGAAACTGG TGAACGACTG CACAGAGGTC AGCAAAACAG AATGCCAGTC CTGCGGTAAA 
GGCGAATTCT TGTCCACCTG GAACAGAGAG AAATACTGTC ACGAGCACAG ATACTGCAAC 
CCCAACCTAG GGCTCCGGAT CCAGAGCGAG GGCACCTTGA ATACAGACAC CACTTGTGTA 
TGTGTCGAAG GCCAACACTG TACCAGTCAC ACCTGCGAAA GTTGCACGCC CCACAGCTTG 
TGTCTCCCTG GCTTCGGGGT CAAGCAGATC GCTACAGGGC TTTTGGATAC CGTCTGTGAA 
CCCTGCCCGC TCGGCTTCTT CTCCAACGTG TCATCTGCTT TTGAAAAGTG TCACCGTTGG 
ACAAGCTGCG AGAGAAAAGG CCTGGTGGAA CAACACGTGG GGACGAACAA GACAGATGTT 
GTCTGCGGTT TCCAGAGTCG GATGAGGACC CTGGTGGTGA TCCCCGTCAC GATGGGAGTC 
CTGTTTGCTG TCCTGTTGGT ATCTGCCTGT ATCAGTGAGT CCCCAGGGAA CATAACCAAG 
AAGCGGCAGG CTAAGGCCCT GCACCCTACG GCTGAAAGGC AGGATCCCGT GGAGACGATT 
GATCCGGAGG ATTTTCCCGG CCCCCACCCG CCTCCTCCGG TGCAAGAGAC CTTATGCTGG 
TGTCAGCCGG TCGCCCAGGA GGACGGCAAA GAGAGCCGCA TCTCCGTGCA GGAGCGAGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clinical disease upregulates expression of CD40 and CD40 ligand on peripheral blood mononuclear cells from cattle naturally infected with Mycobacterium avium subsp. paratuberculosis.
Clinical and vaccine immunology : CVI20(8)1274-82(2013 Aug)
Khalifeh MS,Stabel JR

Mycobacterium avium subspecies paratuberculosis suppresses expression of IL-12p40 and iNOS genes induced by signalling through CD40 in bovine monocyte-derived macrophages.
Veterinary immunology and immunopathology128(1-3)44-52(2009 Mar)
Sommer S,Pudrith CB,Colvin CJ,Coussens PM

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Cloning, expression and biological function of the bovine CD40 homologue: role in B-lymphocyte growth and differentiation in cattle.
Immunology90(2)294-300(1997 Feb)
Hirano A,Brown WC,Estes DM

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CD40 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム