| Gene Symbol | PLAT |
| Entrez Gene ID | 397121 |
| Full Name | plasminogen activator, tissue type |
| Gene Type | protein-coding |
| Organism | Sus scrofa(Pig) |
| Genome |
ORF » Species Summary » Sus scrofa » PLAT cDNA ORF clone
| Gene Symbol | PLAT |
| Entrez Gene ID | 397121 |
| Full Name | plasminogen activator, tissue type |
| Gene Type | protein-coding |
| Organism | Sus scrofa(Pig) |
| Genome |
| mRNA | Protein | Name |
|---|---|---|
| NM_214054.1 | NP_999219.1 | tissue-type plasminogen activator precursor |
| XM_005657646.2 | XP_005657703.1 | tissue-type plasminogen activator isoform X1 |
| XM_005657647.2 | XP_005657704.1 | tissue-type plasminogen activator isoform X2 |
Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes.
Mond?jar I, Grull?n LA, Garc?a-V?zquez FA, Romar R, Coy P
Fertility and sterility97(2)453-61(2012 Feb)
Mild hypothermia markedly reduces ischemia related coronary t-PA release.
van der Pals J, G?tberg M, Olivecrona GK, Brogren H, Jern S, Erlinge D
Journal of thrombosis and thrombolysis29(3)289-95(2010 Apr)
The ADP receptor P2Y(1) mediates t-PA release in pigs during cardiac ischemia.
Olivecrona GK, G?tberg M, Harnek J, Jacobson KA, Jern S, Erlinge D
Journal of thrombosis and thrombolysis24(2)115-22(2007 Oct)
Proteomic and transcriptomic analyses of differential stress/inflammatory responses in mandibular lymph nodes and oropharyngeal tonsils of European wild boars naturally infected with Mycobacterium bovis.
Naranjo V, Villar M, Mart?n-Hernando MP, Vidal D, H?fle U, Gortazar C, Kocan KM, V?zquez J, de la Fuente J
Proteomics7(2)220-31(2007 Jan)
PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences.
Uenishi H, Eguchi-Ogawa T, Shinkai H, Okumura N, Suzuki K, Toki D, Hamasima N, Awata T
Nucleic acids research35(Database issue)D650-3(2007 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The plasminogen/plasminogen activator/plasmin system is activated during gamete interaction and regulates the sperm entry into the oocyte.
Title: Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes.
Mild experimental hypothermia markedly reduces ischemia-related coronary tissue plasminogen activator release, which may contribute to the cardioprotective effect of hypothermia.
Title: Mild hypothermia markedly reduces ischemia related coronary t-PA release.
ADP acting on the endothelial P2Y(1) M receptor may mediate release of t-PA during ischemia and post-ischemic hyperemia, an effect that may counteract some of the platelet activating effects of ADP
Title: The ADP receptor P2Y(1) mediates t-PA release in pigs during cardiac ischemia.
a fast beta2 agonist-mediated local release of t-PA into the coronary vasculature was demonstrated. For total t-PA, this response was characterised by a biphasic release profile
Title: Intracoronary beta2 receptor activation induces dynamic local t-PA release in the pig.
The following PLAT gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLAT cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe00807 | |
| Clone ID Related Accession (Same CDS sequence) | NM_214054.1 | |
| Accession Version | NM_214054.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1689bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-15 | |
| Organism | Sus scrofa(pig) | |
| Product | tissue-type plasminogen activator precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF364605.1. ##Evidence-Data-START## Transcript exon combination :: AF364605.1, AK234864.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1487398, SAMEA1487410 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGTATGCAC TGAAGAGAGA GCTCTGGTGT GTGCTCCTGC TGTGTGGGGC CATCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_999219.1 |
| CDS | 100..1788 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_214054.1 |
1 | ATGTATGCAC TGAAGAGAGA GCTCTGGTGT GTGCTCCTGC TGTGTGGGGC CATCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe24594 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005657646.2 | |
| Accession Version | XM_005657646.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1737bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2015-09-10 | |
| Organism | Sus scrofa(Pig) | |
| Product | tissue-type plasminogen activator isoform X1 | |
| Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003536616.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005657646.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTATGCAC TGAAGAGAGA GCTCTGGTGT GTGCTCCTGC TGTGTGGGGC CATCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_005657703.1 |
| CDS | 199..1935 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_005657646.2 |
1 | ATGTATGCAC TGAAGAGAGA GCTCTGGTGT GTGCTCCTGC TGTGTGGGGC CATCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe24595 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005657647.2 | |
| Accession Version | XM_005657647.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2015-09-10 | |
| Organism | Sus scrofa(Pig) | |
| Product | tissue-type plasminogen activator isoform X2 | |
| Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003536616.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005657647.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTATGCAC TGAAGAGAGA GCTCTGGTGT GTGCTCCTGC TGTGTGGGGC CATCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_005657704.1 |
| CDS | 203..1675 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_005657647.2 |
1 | ATGTATGCAC TGAAGAGAGA GCTCTGGTGT GTGCTCCTGC TGTGTGGGGC CATCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes. |
Mild hypothermia markedly reduces ischemia related coronary t-PA release. |
The ADP receptor P2Y(1) mediates t-PA release in pigs during cardiac ischemia. |
Proteomic and transcriptomic analyses of differential stress/inflammatory responses in mandibular lymph nodes and oropharyngeal tonsils of European wild boars naturally infected with Mycobacterium bovis. |
PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. |